UA85528C2 - Днк, кодирующая растительную липазу, трансгенные растения и способ контроля старения у растений - Google Patents
Днк, кодирующая растительную липазу, трансгенные растения и способ контроля старения у растенийInfo
- Publication number
- UA85528C2 UA85528C2 UA2003010421A UA2003010421A UA85528C2 UA 85528 C2 UA85528 C2 UA 85528C2 UA 2003010421 A UA2003010421 A UA 2003010421A UA 2003010421 A UA2003010421 A UA 2003010421A UA 85528 C2 UA85528 C2 UA 85528C2
- Authority
- UA
- Ukraine
- Prior art keywords
- plants
- ageing
- dna coding
- transgenic plants
- plant lipase
- Prior art date
Links
- 230000032683 aging Effects 0.000 title abstract 5
- 239000004367 Lipase Substances 0.000 title abstract 3
- 108090001060 Lipase Proteins 0.000 title abstract 3
- 102000004882 Lipase Human genes 0.000 title abstract 3
- 235000019421 lipase Nutrition 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 230000009261 transgenic effect Effects 0.000 title abstract 2
- 241000196324 Embryophyta Species 0.000 abstract 3
- 108090000623 proteins and genes Proteins 0.000 abstract 3
- 241000219194 Arabidopsis Species 0.000 abstract 1
- 235000009355 Dianthus caryophyllus Nutrition 0.000 abstract 1
- 240000006497 Dianthus caryophyllus Species 0.000 abstract 1
- 230000000692 anti-sense effect Effects 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 230000004048 modification Effects 0.000 abstract 1
- 238000012986 modification Methods 0.000 abstract 1
- 239000002773 nucleotide Substances 0.000 abstract 1
- 125000003729 nucleotide group Chemical group 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
- C12N15/8262—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield involving plant development
- C12N15/8266—Abscission; Dehiscence; Senescence
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
- C12N15/8249—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving ethylene biosynthesis, senescence or fruit development, e.g. modified tomato ripening, cut flower shelf-life
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
- C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
- C12N15/8273—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for drought, cold, salt resistance
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
- C12N9/18—Carboxylic ester hydrolases (3.1.1)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
- C12N9/18—Carboxylic ester hydrolases (3.1.1)
- C12N9/20—Triglyceride splitting, e.g. by means of lipase
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
- C12Q1/6895—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for plants, fungi or algae
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- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B30/00—Methods of screening libraries
- C40B30/04—Methods of screening libraries by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/04—Libraries containing only organic compounds
- C40B40/06—Libraries containing nucleotides or polynucleotides, or derivatives thereof
- C40B40/08—Libraries containing RNA or DNA which encodes proteins, e.g. gene libraries
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Plant Pathology (AREA)
- Cell Biology (AREA)
- Analytical Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Mycology (AREA)
- Botany (AREA)
- Nutrition Science (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
Заявлена регуляция экспрессии старения у растений путем введения гена или фрагмента гена, кодирующего старение-индуцированную липазу, в растительный геном в антисмысловой ориентации. Идентифицированы гены гвоздики и Arabidopsis, кодирующие старение-индуцированную липазу, и нуклеотидные последовательности, использованные для модификации процесса старения у трансгенных растений.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US25028099A | 1999-02-16 | 1999-02-16 | |
| US59777400A | 2000-06-19 | 2000-06-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA85528C2 true UA85528C2 (ru) | 2009-02-10 |
Family
ID=22947104
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UA2003010421A UA85528C2 (ru) | 1999-02-16 | 2001-06-19 | Днк, кодирующая растительную липазу, трансгенные растения и способ контроля старения у растений |
Country Status (14)
| Country | Link |
|---|---|
| US (6) | US6774284B1 (ru) |
| EP (1) | EP1155134B1 (ru) |
| JP (1) | JP4885359B2 (ru) |
| KR (1) | KR20020010119A (ru) |
| CN (1) | CN1354797A (ru) |
| AT (1) | ATE313636T1 (ru) |
| AU (1) | AU778437B2 (ru) |
| CA (1) | CA2362546C (ru) |
| DE (1) | DE60024971D1 (ru) |
| HK (1) | HK1047299A1 (ru) |
| IL (2) | IL144835A0 (ru) |
| NZ (1) | NZ514123A (ru) |
| UA (1) | UA85528C2 (ru) |
| WO (1) | WO2000049164A1 (ru) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6936289B2 (en) | 1995-06-07 | 2005-08-30 | Danisco A/S | Method of improving the properties of a flour dough, a flour dough improving composition and improved food products |
| ES2350891T3 (es) | 1997-04-09 | 2011-01-28 | Danisco A/S | Lipasa y utilización de la misma para mejorar las masas y los productos horneados. |
| WO2001098510A2 (en) * | 2000-06-19 | 2001-12-27 | Senesco Technologies, Inc. | Dna encoding a plant lipase, transgenic plants and a method for controlling senescence in plants |
| IL144835A0 (en) | 1999-02-16 | 2002-06-30 | Senesco Inc | Dna encoding a plant lipase, transgenic plants and a method for controlling senescence in plants |
| AUPQ994600A0 (en) | 2000-09-06 | 2000-09-28 | Agriculture Victoria Services Pty Ltd | Manipulation of plant senescene |
| EP1387616B1 (en) | 2001-05-18 | 2007-05-16 | Danisco A/S | Method of preparing a dough with an enzyme |
| DE602004030000D1 (de) | 2003-01-17 | 2010-12-23 | Danisco | Verfahren zur in-situ-herstellung eines emulgators in einem nahrungsmittel |
| AU2004219649A1 (en) * | 2003-03-10 | 2004-09-23 | Broin And Associates, Inc. | Method for producing ethanol using raw starch |
| US20050233030A1 (en) | 2004-03-10 | 2005-10-20 | Broin And Associates, Inc. | Methods and systems for producing ethanol using raw starch and fractionation |
| US20050239181A1 (en) * | 2004-03-10 | 2005-10-27 | Broin And Associates, Inc. | Continuous process for producing ethanol using raw starch |
| GB0405637D0 (en) | 2004-03-12 | 2004-04-21 | Danisco | Protein |
| EP1776455B1 (en) | 2004-07-16 | 2015-03-18 | DuPont Nutrition Biosciences ApS | Lipolytic enzyme, uses thereof in the food industry |
| US20070037267A1 (en) * | 2005-05-02 | 2007-02-15 | Broin And Associates, Inc. | Methods and systems for producing ethanol using raw starch and fractionation |
| US7919289B2 (en) | 2005-10-10 | 2011-04-05 | Poet Research, Inc. | Methods and systems for producing ethanol using raw starch and selecting plant material |
| US7309602B2 (en) * | 2006-04-13 | 2007-12-18 | Ambrozea, Inc. | Compositions and methods for producing fermentation products and residuals |
| US20070243235A1 (en) * | 2006-04-13 | 2007-10-18 | David Peter R | Compositions and methods for producing fermentation products and residuals |
| US20070244719A1 (en) * | 2006-04-13 | 2007-10-18 | David Peter R | Compositions and methods for producing fermentation products and residuals |
| BRPI0810083B8 (pt) | 2007-03-28 | 2020-10-06 | Monsanto Technology Llc | métodos para estabelecer onde uma planta de soja ou semente de soja deve ser cultivada, de melhoramento da planta de soja, para selecionar uma semente de soja, de distribuição de uma planta de soja, para isolar sementes de soja de maturidade precoce indeterminada, e para determinar se uma planta de soja tem um grupo de maturidade |
| US9049823B2 (en) | 2007-09-11 | 2015-06-09 | Monsanto Technology Llc | Increased alpha-prime beta-conglycinin soybeans |
| WO2010102060A2 (en) * | 2009-03-03 | 2010-09-10 | Poet Research, Inc. | System for pre-treatment of biomass for the production of ethanol |
| US9068206B1 (en) | 2009-03-03 | 2015-06-30 | Poet Research, Inc. | System for treatment of biomass to facilitate the production of ethanol |
| MX2011009269A (es) | 2009-03-03 | 2011-09-26 | Poet Res Inc | Fermentacion de biomasa para la produccion de etanol. |
| US8450094B1 (en) | 2009-03-03 | 2013-05-28 | Poet Research, Inc. | System for management of yeast to facilitate the production of ethanol |
| US8839078B2 (en) * | 2010-03-05 | 2014-09-16 | Samsung Electronics Co., Ltd. | Application layer FEC framework for WiGig |
| WO2014041116A1 (en) | 2012-09-17 | 2014-03-20 | F. Hoffmann-La Roche Ag | Method for the production of polypeptides in the periplasm of prokaryotic cells |
| EP2958713B1 (en) | 2013-02-20 | 2019-05-08 | Benchmade Knife Co., Inc. | Folding knife with dual operational modes |
| WO2019055431A1 (en) * | 2017-09-12 | 2019-03-21 | The Regents Of The University Of California | PEPTIDE INHIBITORS OF INSULIN DEGRADATION ENZYME |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9318927D0 (en) * | 1993-09-13 | 1993-10-27 | Zeneca Ltd | Regulation of senescence |
| FR2722798B1 (fr) | 1994-07-25 | 1996-09-13 | Toulouse Inst Nat Polytech | 1procede de production d'acides gras2plantes oleagineuses |
| US5689042A (en) | 1995-03-29 | 1997-11-18 | Wisconsin Alumni Research Foundation | Transgenic plants with altered senescence characteristics |
| AUPN286295A0 (en) * | 1995-05-09 | 1995-07-06 | Allrad No.1 Pty Ltd | Transgenic carnations exhibit prolonged post-harvest life |
| CA2234107A1 (en) * | 1995-10-13 | 1997-04-17 | Purdue Research Foundation | Improvement of fruit quality by inhibiting production of lipoxygenase in fruits |
| US5824875A (en) | 1996-10-01 | 1998-10-20 | Colorado State University Through Its Agent Colorado State University Research Foundation | 1-aminocyclopropane-1-carboxylate synthase genes from pelargonium |
| GB9817909D0 (en) | 1998-08-17 | 1998-10-14 | Zeneca Ltd | DNA constructs |
| IL144835A0 (en) | 1999-02-16 | 2002-06-30 | Senesco Inc | Dna encoding a plant lipase, transgenic plants and a method for controlling senescence in plants |
| EP1033405A3 (en) | 1999-02-25 | 2001-08-01 | Ceres Incorporated | Sequence-determined DNA fragments and corresponding polypeptides encoded thereby |
-
2000
- 2000-02-14 IL IL14483500A patent/IL144835A0/xx unknown
- 2000-02-14 EP EP00914569A patent/EP1155134B1/en not_active Expired - Lifetime
- 2000-02-14 AU AU35942/00A patent/AU778437B2/en not_active Ceased
- 2000-02-14 JP JP2000599888A patent/JP4885359B2/ja not_active Expired - Fee Related
- 2000-02-14 WO PCT/US2000/003494 patent/WO2000049164A1/en not_active Ceased
- 2000-02-14 KR KR1020017010405A patent/KR20020010119A/ko not_active Ceased
- 2000-02-14 DE DE60024971T patent/DE60024971D1/de not_active Expired - Lifetime
- 2000-02-14 HK HK02108970.5A patent/HK1047299A1/zh unknown
- 2000-02-14 CA CA2362546A patent/CA2362546C/en not_active Expired - Fee Related
- 2000-02-14 NZ NZ514123A patent/NZ514123A/en not_active IP Right Cessation
- 2000-02-14 CN CN00806296A patent/CN1354797A/zh active Pending
- 2000-02-14 AT AT00914569T patent/ATE313636T1/de not_active IP Right Cessation
- 2000-07-05 US US09/610,104 patent/US6774284B1/en not_active Expired - Fee Related
-
2001
- 2001-06-19 UA UA2003010421A patent/UA85528C2/ru unknown
- 2001-08-09 IL IL144835A patent/IL144835A/en not_active IP Right Cessation
-
2003
- 2003-10-01 US US10/674,540 patent/US7087419B2/en not_active Expired - Fee Related
-
2006
- 2006-07-14 US US11/486,250 patent/US20070011778A1/en not_active Abandoned
-
2007
- 2007-10-10 US US11/870,229 patent/US20080039335A1/en not_active Abandoned
-
2011
- 2011-04-04 US US13/079,563 patent/US20110196143A1/en not_active Abandoned
-
2012
- 2012-07-18 US US13/551,847 patent/US20130184449A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20130184449A1 (en) | 2013-07-18 |
| HK1047299A1 (zh) | 2003-02-14 |
| US20070011778A1 (en) | 2007-01-11 |
| NZ514123A (en) | 2003-10-31 |
| US20110196143A1 (en) | 2011-08-11 |
| IL144835A0 (en) | 2002-06-30 |
| WO2000049164A9 (en) | 2002-04-11 |
| AU3594200A (en) | 2000-09-04 |
| CA2362546A1 (en) | 2000-08-24 |
| ATE313636T1 (de) | 2006-01-15 |
| IL144835A (en) | 2014-07-31 |
| EP1155134B1 (en) | 2005-12-21 |
| KR20020010119A (ko) | 2002-02-02 |
| EP1155134A1 (en) | 2001-11-21 |
| WO2000049164A1 (en) | 2000-08-24 |
| JP4885359B2 (ja) | 2012-02-29 |
| DE60024971D1 (de) | 2006-01-26 |
| US20080039335A1 (en) | 2008-02-14 |
| CA2362546C (en) | 2012-05-15 |
| US6774284B1 (en) | 2004-08-10 |
| JP2002536979A (ja) | 2002-11-05 |
| AU778437B2 (en) | 2004-12-02 |
| CN1354797A (zh) | 2002-06-19 |
| US7087419B2 (en) | 2006-08-08 |
| US20040158891A1 (en) | 2004-08-12 |
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