UA83628C2 - Способ защиты эндотелиальных и эпителиальных клеток во время трансплантации алогенных стволовых клеток - Google Patents
Способ защиты эндотелиальных и эпителиальных клеток во время трансплантации алогенных стволовых клетокInfo
- Publication number
- UA83628C2 UA83628C2 UA20041109654A UA20041109654A UA83628C2 UA 83628 C2 UA83628 C2 UA 83628C2 UA 20041109654 A UA20041109654 A UA 20041109654A UA 20041109654 A UA20041109654 A UA 20041109654A UA 83628 C2 UA83628 C2 UA 83628C2
- Authority
- UA
- Ukraine
- Prior art keywords
- endothelial
- protection
- stem cell
- epithelial cells
- cell transplantation
- Prior art date
Links
- 230000000735 allogeneic effect Effects 0.000 title 1
- 210000002889 endothelial cell Anatomy 0.000 title 1
- 230000003511 endothelial effect Effects 0.000 title 1
- 210000002919 epithelial cell Anatomy 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 238000011476 stem cell transplantation Methods 0.000 title 1
- 108091034117 Oligonucleotide Proteins 0.000 abstract 1
- 229940124276 oligodeoxyribonucleotide Drugs 0.000 abstract 1
- 230000001681 protective effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
- A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Toxicology (AREA)
- Transplantation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Materials For Medical Uses (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US38411402P | 2002-05-31 | 2002-05-31 | |
| US38743802P | 2002-06-11 | 2002-06-11 | |
| PCT/EP2003/005753 WO2003101468A1 (en) | 2002-05-31 | 2003-06-02 | Method for the protection of endothelial and epithelial cells during chemotherapy |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA83628C2 true UA83628C2 (ru) | 2008-08-11 |
Family
ID=29715309
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UA20041109654A UA83628C2 (ru) | 2002-05-31 | 2003-06-02 | Способ защиты эндотелиальных и эпителиальных клеток во время трансплантации алогенных стволовых клеток |
Country Status (16)
| Country | Link |
|---|---|
| EP (1) | EP1509235A1 (sr) |
| JP (1) | JP2005527636A (sr) |
| CN (1) | CN1304011C (sr) |
| AU (1) | AU2003238189A1 (sr) |
| CA (1) | CA2487171A1 (sr) |
| EA (1) | EA008213B1 (sr) |
| HR (1) | HRP20041213A2 (sr) |
| IL (1) | IL165353A0 (sr) |
| IS (1) | IS7548A (sr) |
| MX (1) | MXPA04011941A (sr) |
| NO (1) | NO20045655L (sr) |
| NZ (1) | NZ536864A (sr) |
| PL (1) | PL374402A1 (sr) |
| RS (1) | RS102504A (sr) |
| UA (1) | UA83628C2 (sr) |
| WO (1) | WO2003101468A1 (sr) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ITMI20031714A1 (it) * | 2003-09-05 | 2005-03-06 | Gentium Spa | Formazioni ad azione antitumorale. |
| DK2637672T3 (en) | 2010-11-12 | 2018-10-22 | Gentium S R L | DEFIBROTID FOR USE IN PROPHYLAXY AND / OR TREATMENT OF GRAPHIC VERSUS HOST DISEASE (GVHD) |
| US9902952B2 (en) | 2012-06-22 | 2018-02-27 | Gentrum S.R.L. | Euglobulin-based method for determining the biological activity of defibrotide |
| EP3026122A1 (en) * | 2014-11-27 | 2016-06-01 | Gentium S.p.A. | Cellular-based method for determining the potency of defibrotide |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998048843A1 (en) * | 1997-04-28 | 1998-11-05 | Arsinur Burcoglu | Method of treating hiv infection and related secondary infections thereof |
-
2003
- 2003-06-02 NZ NZ536864A patent/NZ536864A/en unknown
- 2003-06-02 PL PL03374402A patent/PL374402A1/xx not_active Application Discontinuation
- 2003-06-02 CA CA002487171A patent/CA2487171A1/en not_active Abandoned
- 2003-06-02 JP JP2004508823A patent/JP2005527636A/ja active Pending
- 2003-06-02 WO PCT/EP2003/005753 patent/WO2003101468A1/en active Application Filing
- 2003-06-02 EP EP03735516A patent/EP1509235A1/en not_active Withdrawn
- 2003-06-02 RS YU102504A patent/RS102504A/sr unknown
- 2003-06-02 CN CNB038125013A patent/CN1304011C/zh not_active Expired - Fee Related
- 2003-06-02 EA EA200401448A patent/EA008213B1/ru not_active IP Right Cessation
- 2003-06-02 UA UA20041109654A patent/UA83628C2/ru unknown
- 2003-06-02 AU AU2003238189A patent/AU2003238189A1/en not_active Abandoned
- 2003-06-02 MX MXPA04011941A patent/MXPA04011941A/es unknown
-
2004
- 2004-11-23 IL IL16535304A patent/IL165353A0/xx unknown
- 2004-11-24 IS IS7548A patent/IS7548A/is unknown
- 2004-12-27 NO NO20045655A patent/NO20045655L/no not_active Application Discontinuation
- 2004-12-27 HR HR20041213A patent/HRP20041213A2/xx not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| NZ536864A (en) | 2008-08-29 |
| JP2005527636A (ja) | 2005-09-15 |
| EA008213B1 (ru) | 2007-04-27 |
| MXPA04011941A (es) | 2005-07-26 |
| AU2003238189A1 (en) | 2003-12-19 |
| IL165353A0 (en) | 2006-01-15 |
| WO2003101468A1 (en) | 2003-12-11 |
| NO20045655L (no) | 2004-12-27 |
| PL374402A1 (en) | 2005-10-17 |
| IS7548A (is) | 2004-11-24 |
| RS102504A (en) | 2006-12-15 |
| HRP20041213A2 (en) | 2006-04-30 |
| EA200401448A1 (ru) | 2005-06-30 |
| CA2487171A1 (en) | 2003-12-11 |
| EP1509235A1 (en) | 2005-03-02 |
| CN1304011C (zh) | 2007-03-14 |
| CN1655801A (zh) | 2005-08-17 |
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