UA66930C2 - Похідні 4'-демікарозил-8а-аза-8а-гомотилозину - Google Patents

Похідні 4'-демікарозил-8а-аза-8а-гомотилозину

Info

Publication number
UA66930C2
UA66930C2 UA2001129085A UA2001129085A UA66930C2 UA 66930 C2 UA66930 C2 UA 66930C2 UA 2001129085 A UA2001129085 A UA 2001129085A UA 2001129085 A UA2001129085 A UA 2001129085A UA 66930 C2 UA66930 C2 UA 66930C2
Authority
UA
Ukraine
Prior art keywords
derivatives
homotylosin
demycarosyl
aza
acyl
Prior art date
Application number
UA2001129085A
Other languages
English (en)
Russian (ru)
Inventor
Невенка ЛОПОТАР
Амалія Нарандя
Стєпан Мутак
Original Assignee
Пліва Д.Д.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Пліва Д.Д. filed Critical Пліва Д.Д.
Publication of UA66930C2 publication Critical patent/UA66930C2/uk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)

Abstract

Цей винахід стосується похідних 4'-демікарозил-8a-аза-8a-гомотилозину формули I , де R означає CHO, CH(OCH3)2 або CH2N[CH2(C6H5)]2, R1 означає H або С1-C3 ацил, R2 означає OR6, і R6 означає H або С1-C3 ацил, R3 означає H, або R2 і R3 разом означають =О, R4 означає OH, R5 означає H, або R4 і R5 разом означають =O, та способу їх одержання. Нові похідні виявляють протимікробну дію і можуть також використовуватись як проміжні сполуки при одержанні нових 17-членних азалідних антибіотиків.
UA2001129085A 1999-06-11 2000-06-06 Похідні 4'-демікарозил-8а-аза-8а-гомотилозину UA66930C2 (uk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HR990192A HRP990192A2 (en) 1999-06-11 1999-06-11 4'-DEMICAROZYL-8a-AZA-8a-HOMOTHILOSINE DERIVATIVES
PCT/HR2000/000018 WO2000077016A1 (en) 1999-06-11 2000-06-06 DERIVATIVES OF 4'-DEMYCAROSYL-8a-AZA-8a-HOMOTYLOSIN

Publications (1)

Publication Number Publication Date
UA66930C2 true UA66930C2 (uk) 2004-06-15

Family

ID=10946940

Family Applications (1)

Application Number Title Priority Date Filing Date
UA2001129085A UA66930C2 (uk) 1999-06-11 2000-06-06 Похідні 4'-демікарозил-8а-аза-8а-гомотилозину

Country Status (13)

Country Link
EP (1) EP1189914A1 (uk)
JP (1) JP2003502338A (uk)
AU (1) AU767543B2 (uk)
CA (1) CA2375812A1 (uk)
CZ (1) CZ20014362A3 (uk)
EA (1) EA200200026A1 (uk)
HR (1) HRP990192A2 (uk)
HU (1) HUP0201610A3 (uk)
NO (1) NO322424B1 (uk)
SK (1) SK17572001A3 (uk)
UA (1) UA66930C2 (uk)
WO (1) WO2000077016A1 (uk)
YU (1) YU87401A (uk)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR043050A1 (es) 2002-09-26 2005-07-13 Rib X Pharmaceuticals Inc Compuestos heterociclicos bifuncionales y metodos para preparar y usar los mismos
JP2006523229A (ja) * 2003-03-05 2006-10-12 リブ−エックス ファーマシューティカルズ，インコーポレイテッド 二官能性複素環式化合物ならびにその製造および使用方法
JPWO2005019238A1 (ja) 2003-08-22 2006-10-19 明治製菓株式会社 新規アザライド及びアザラクタム誘導体とその製造法
EP2716647A3 (en) 2004-02-27 2014-08-20 Rib-X Pharmaceuticals, Inc. Macrocyclic compounds and methods of making and using the same

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
YU45033B (en) * 1987-04-14 1991-06-30 Pliva Zagreb Process for preparing 10,11,12,13-tetrahydro derivative
YU149889A (en) * 1989-07-26 1991-02-28 Pliva Zagreb Process for preparing biologically active derivatives of tylozine
CZ211798A3 (cs) * 1997-07-16 1999-02-17 Pliva, Farmaceutska, Kemijska, Prehrambena I Kozmetička Industrije, Dioničko Društvo Lineární 8a-sekoazalidy a způsob jejich výroby

Also Published As

Publication number Publication date
CA2375812A1 (en) 2000-12-21
NO20016030D0 (no) 2001-12-10
AU5558300A (en) 2001-01-02
AU767543B2 (en) 2003-11-13
HRP990192A2 (en) 2001-04-30
HUP0201610A3 (en) 2003-03-28
NO20016030L (no) 2002-01-30
WO2000077016A1 (en) 2000-12-21
YU87401A (sh) 2004-07-15
JP2003502338A (ja) 2003-01-21
NO322424B1 (no) 2006-10-02
HUP0201610A2 (en) 2002-10-28
SK17572001A3 (sk) 2002-04-04
EA200200026A1 (ru) 2002-06-27
CZ20014362A3 (cs) 2002-04-17
EP1189914A1 (en) 2002-03-27

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