UA64186A - Disinfectant - Google Patents

Abstract

The disinfectant comprises bischofite salt and the water.

Description

Description of the invention

Recently (from 1995 to 2001), many substances have been proposed for disinfection of facilities 2 and cleaning of medical devices. These are Chlorantoin (TU U 22902465. 004-95) (1995), Aerodesin 2000 (1996), Lysoformin 2000 (1994), Desactin (2000), and Lysoformin 3000 (2001). These dosage forms are approved

by the Ministry of Health of Ukraine (2, Z, 4, 5). Each of them has its own disadvantages, such as high cost, high acute toxicity, and others.

As a prototype (Ministry of Health of Ukraine. Guidelines for the use of 70 Lisoformin 3000 for the purpose of disinfection, pre-sterilization cleaning and sterilization. - Kyiv, 2001) we use Lisoformin 3000, which is produced by a Swiss company. The drug is a transparent blue liquid. 100g of concentrate contains: gutaraldehyde - 9.5g, glyoxal - 7.5g, dididyldimethylammonium chloride - 9.bg, the rest - nonionic surfactants, corrosion inhibitors, stabilizers, dyes and water. 12 Lisoformin ZO00 has some disadvantages: it belongs to the Z class of acute toxicity, irritates the skin, mucous membrane of the eyes, and upper respiratory tract. In addition, it is a foreign drug with a high cost.

The proposed solution of bischofite, for which a diploma of scientific discovery in the field of medicine was obtained according to Mo 75 "Properties of bischofite will suppress the growth and reproduction of pathogenic and conditionally pathogenic microorganisms", does not have these shortcomings (1). As proven by laboratory and clinical studies, it is characterized by inhibiting the growth and reproduction of pathogenic, opportunistic pathogens and possessing immunomodulatory properties. This bischofite solution (3095) has an acute toxicity of class 4, does not irritate the human skin upon contact, does not irritate the mucous layers. Therefore, its use for disinfection differs from previously used substances. The results of laboratory and clinical studies proved that the 3095 bischofite solution exhibits antagonistic activity, which was detected in relation to the following microorganisms (table.). "

The presence of an antagonistic, and for fungi, bacteriostatic effect makes the use of this solution promising as an antiseptic.

The antagonistic activity of the bischofite solution was proven when it was applied to the infected urine of patients with urolithiasis. The immunomodulating properties of bischofite solution were studied at the Lyon clinic (France) under the auspices of professors N. Miiop and 0. Kogop. with

Studies have shown that: -Aqueous solution of bishofit ip mygo is capable in the concentration range from 710" to 10"bg/l, to activate - redox metabolism of phagocytes and, as a result, to increase the phagocytic activity of cells. ChI - Both populations of phagocytes-monocytes and neutrophils are subject to an activating effect: with a more intensive effect on monocytes at a concentration of 10 g/l with a duration of preincubation of at least 45 minutes, and for neutrophils at a concentration of 10 g/l and an incubation period of no less than 60 minutes. -Aqueous bischofite solution probably increases the spontaneous level of phagocyte activation.

Thus, it was established that bischofite solution has bacteriostatic, bactericidal and immunomodulating properties. This makes it possible to formulate the formula of the invention in the following wording: -o

An antiseptic solution containing salt and water, which differs in that bischophyte salt is used as the active ingredient. ;"

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References 1. Dzyak G.V., Zorin A.N., Muntyan S.A., Kremenchutskyi H.M. etc. The properties of bischofite suppress the growth and reproduction of pathogenic and conditionally pathogenic microorganisms. Discovery M 75 .// Bull. Mr. VAK of the Russian Federation, 1998. -

P 11. 2. Use of lysoformin 3000 for the purpose of pre-sterilization cleaning, disinfection, sterilization /

Methodical instructions. Ministry of Health of Ukraine.-Kyiv, 1999.-vs. 60 3. Use of azrodezin 2000 for disinfection purposes / Methodological instructions. Ministry of Health of Ukraine. - Kyiv, 1996. - From p. 4. Chlorantoin. Disinfectants of domestic manufacturers // Disinfection and hygiene. - Kyiv, 1999 -- Zs. 5. Regarding the use of desactin for the purpose of disinfection of objects and pre-sterilization cleaning of medical products / Methodological instructions. Ministry of Health of Ukraine, Kyiv, 2000 - 20 p. b5

Claims (1)

The formula of the invention Antiseptic solution containing salt and water, which differs in that 2 vil bischofite is used as an active substance. Official bulletin "Industrial Property". Book 1 "Inventions, useful models, topographies of integrated microcircuits", 2004, M 2, 15.02.2004. State Department of Intellectual Property of the Ministry of Education and Science of Ukraine. « (Se) s "- " (Se) - s ;" (22) sh» - at 50 42) 60 b5