UA42719C2 - Сполуки, композиції та способи, які інгібують протеази, для лікування та профілактики імуномедіаторних запальних хвороб - Google Patents

Сполуки, композиції та способи, які інгібують протеази, для лікування та профілактики імуномедіаторних запальних хвороб

Info

Publication number
UA42719C2
UA42719C2 UA95104466A UA95104466A UA42719C2 UA 42719 C2 UA42719 C2 UA 42719C2 UA 95104466 A UA95104466 A UA 95104466A UA 95104466 A UA95104466 A UA 95104466A UA 42719 C2 UA42719 C2 UA 42719C2
Authority
UA
Ukraine
Prior art keywords
compositions
treatment
methods
inflammatory disorders
immunomediated inflammatory
Prior art date
Application number
UA95104466A
Other languages
English (en)
Russian (ru)
Ukrainian (uk)
Inventor
Керрі Спеар
Керри Спеар
Чарльз Джонсон
Хайнц Гшвенд
Original Assignee
Аксіз Фармасьютікелз, Інк
Аксиз Фармасьютикелз, Инк
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Аксіз Фармасьютікелз, Інк, Аксиз Фармасьютикелз, Инк filed Critical Аксіз Фармасьютікелз, Інк
Publication of UA42719C2 publication Critical patent/UA42719C2/uk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06086—Dipeptides with the first amino acid being basic
    • C07K5/06095—Arg-amino acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06086—Dipeptides with the first amino acid being basic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
UA95104466A 1993-03-12 1994-03-11 Сполуки, композиції та способи, які інгібують протеази, для лікування та профілактики імуномедіаторних запальних хвороб UA42719C2 (uk)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US3077093A 1993-03-12 1993-03-12
US3118793A 1993-03-12 1993-03-12
PCT/US1994/002706 WO1994020527A1 (en) 1993-03-12 1994-03-11 Compositions and methods for the treatment of immunomediated inflammatory disorders

Publications (1)

Publication Number Publication Date
UA42719C2 true UA42719C2 (uk) 2001-11-15

Family

ID=26706445

Family Applications (1)

Application Number Title Priority Date Filing Date
UA95104466A UA42719C2 (uk) 1993-03-12 1994-03-11 Сполуки, композиції та способи, які інгібують протеази, для лікування та профілактики імуномедіаторних запальних хвороб

Country Status (11)

Country Link
EP (1) EP0688337A1 (zh)
JP (1) JPH08507768A (zh)
KR (1) KR100309616B1 (zh)
CN (2) CN1057772C (zh)
AU (1) AU683459B2 (zh)
CZ (1) CZ289930B6 (zh)
FI (1) FI954245A (zh)
PL (1) PL176941B1 (zh)
SK (1) SK282537B6 (zh)
UA (1) UA42719C2 (zh)
WO (1) WO1994020527A1 (zh)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0763016B1 (en) * 1994-06-01 2000-01-26 Axys Pharmaceuticals, Inc. Compositions and methods for treating mast-cell mediated conditions
US6022969A (en) 1994-09-23 2000-02-08 Axys Pharmaceuticals, Inc. Compositions and methods for treating mast-cell mediated conditions
US6388122B1 (en) 1996-04-10 2002-05-14 Ono Pharmaceutical Co., Ltd. Tryptase inhibitor and novel guanidino derivatives
CZ29799A3 (cs) * 1996-07-30 1999-06-16 Arris Pharmaceutical Corporation Disubstituovaná cyklická sloučenina, způsob její výroby, farmaceutický přípravek a způsob léčení onemocnění živočicha
WO1998024886A1 (en) * 1996-12-04 1998-06-11 Brigham And Women's Hospital, Inc. Mast cell protease that cleaves fibrinogen
WO1998033812A1 (en) * 1997-02-05 1998-08-06 Brigham And Women's Hospital, Inc. Mast cell protease peptide inhibitors
WO1999024407A1 (en) * 1997-11-10 1999-05-20 Array Biopharma, Inc. Compounds which inhibit tryptase activity
US6221914B1 (en) 1997-11-10 2001-04-24 Array Biopharma Inc. Sulfonamide bridging compounds that inhibit tryptase activity
WO1999026925A1 (fr) * 1997-11-26 1999-06-03 Yoshitomi Pharmaceutical Industries, Ltd. Inhibiteurs de tryptase comprenant des composants d'amide heterocycliques
SE9800729L (sv) * 1998-03-06 1999-09-07 Scotia Lipidteknik Ab Ny topikal formulering I
SE515982C2 (sv) * 1998-03-06 2001-11-05 Lipocore Holding Ab Användning av en olja-i-vatten emulsion som bärare för framställning av en topikal kräm eller lotion
DE19939910A1 (de) * 1999-08-23 2001-03-01 Morphochem Ag Neue Verbindungen, die Tryptase-Aktivität hemmen
GB0507577D0 (en) 2005-04-14 2005-05-18 Novartis Ag Organic compounds

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4201863A (en) * 1974-11-08 1980-05-06 Mitsubishi Chemical Industries, Limited N2 -Arylsulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof
US4456595A (en) * 1982-12-06 1984-06-26 E. R. Squibb & Sons, Inc. Carboxy and substituted carboxy aroly peptides

Also Published As

Publication number Publication date
AU683459B2 (en) 1997-11-13
CN1119019A (zh) 1996-03-20
FI954245A (fi) 1995-09-28
CN1057772C (zh) 2000-10-25
SK112995A3 (en) 1996-10-02
CZ232195A3 (en) 1996-07-17
WO1994020527A1 (en) 1994-09-15
CZ289930B6 (cs) 2002-04-17
EP0688337A1 (en) 1995-12-27
CN1234229A (zh) 1999-11-10
SK282537B6 (sk) 2002-10-08
JPH08507768A (ja) 1996-08-20
PL310559A1 (en) 1995-12-27
KR100309616B1 (ko) 2002-02-28
AU6364794A (en) 1994-09-26
FI954245A0 (fi) 1995-09-11
PL176941B1 (pl) 1999-08-31

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