UA105516U - Способ остановки кровотечения из сосудов разного типа - Google Patents
Способ остановки кровотечения из сосудов разного типа Download PDFInfo
- Publication number
- UA105516U UA105516U UAU201508621U UAU201508621U UA105516U UA 105516 U UA105516 U UA 105516U UA U201508621 U UAU201508621 U UA U201508621U UA U201508621 U UAU201508621 U UA U201508621U UA 105516 U UA105516 U UA 105516U
- Authority
- UA
- Ukraine
- Prior art keywords
- bandage
- chitosan
- temperature
- bleeding
- freezing
- Prior art date
Links
- 230000000740 bleeding effect Effects 0.000 title claims abstract description 36
- 238000000034 method Methods 0.000 title claims abstract description 31
- 210000004204 blood vessel Anatomy 0.000 title claims abstract description 4
- 229920001661 Chitosan Polymers 0.000 claims abstract description 22
- 239000000463 material Substances 0.000 claims abstract description 17
- 238000001035 drying Methods 0.000 claims abstract description 9
- 230000002439 hemostatic effect Effects 0.000 claims abstract description 9
- 102000008186 Collagen Human genes 0.000 claims abstract description 6
- 108010035532 Collagen Proteins 0.000 claims abstract description 6
- 229920002678 cellulose Polymers 0.000 claims abstract description 6
- 239000001913 cellulose Substances 0.000 claims abstract description 6
- 229920001436 collagen Polymers 0.000 claims abstract description 6
- 230000007556 vascular defect Effects 0.000 claims abstract description 3
- 208000027418 Wounds and injury Diseases 0.000 claims description 22
- 238000007710 freezing Methods 0.000 claims description 18
- 230000008014 freezing Effects 0.000 claims description 18
- 206010052428 Wound Diseases 0.000 claims description 15
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims description 12
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 8
- 238000003825 pressing Methods 0.000 claims description 7
- 239000013543 active substance Substances 0.000 claims description 6
- 238000004108 freeze drying Methods 0.000 claims description 6
- 238000003980 solgel method Methods 0.000 claims description 6
- 239000000203 mixture Substances 0.000 claims description 5
- 238000001266 bandaging Methods 0.000 claims description 4
- 235000019441 ethanol Nutrition 0.000 claims description 4
- 239000003795 chemical substances by application Substances 0.000 claims description 3
- 238000001816 cooling Methods 0.000 claims description 3
- 239000004480 active ingredient Substances 0.000 abstract 1
- 238000001879 gelation Methods 0.000 abstract 1
- 208000032843 Hemorrhage Diseases 0.000 description 27
- 210000001105 femoral artery Anatomy 0.000 description 9
- 230000015572 biosynthetic process Effects 0.000 description 8
- 230000006378 damage Effects 0.000 description 8
- 208000007536 Thrombosis Diseases 0.000 description 7
- 208000014674 injury Diseases 0.000 description 7
- 210000001519 tissue Anatomy 0.000 description 7
- 241001465754 Metazoa Species 0.000 description 5
- 210000004369 blood Anatomy 0.000 description 5
- 239000008280 blood Substances 0.000 description 5
- 239000003814 drug Substances 0.000 description 5
- 230000000694 effects Effects 0.000 description 5
- 229940079593 drug Drugs 0.000 description 4
- 239000010410 layer Substances 0.000 description 4
- 230000009885 systemic effect Effects 0.000 description 4
- 241000283973 Oryctolagus cuniculus Species 0.000 description 3
- 238000010171 animal model Methods 0.000 description 3
- 210000000709 aorta Anatomy 0.000 description 3
- 230000023597 hemostasis Effects 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 229960002684 aminocaproic acid Drugs 0.000 description 2
- 210000003743 erythrocyte Anatomy 0.000 description 2
- RBTARNINKXHZNM-UHFFFAOYSA-K iron trichloride Chemical compound Cl[Fe](Cl)Cl RBTARNINKXHZNM-UHFFFAOYSA-K 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- 210000004872 soft tissue Anatomy 0.000 description 2
- 210000004304 subcutaneous tissue Anatomy 0.000 description 2
- 238000011477 surgical intervention Methods 0.000 description 2
- 238000005303 weighing Methods 0.000 description 2
- SLXKOJJOQWFEFD-UHFFFAOYSA-N 6-aminohexanoic acid Chemical compound NCCCCCC(O)=O SLXKOJJOQWFEFD-UHFFFAOYSA-N 0.000 description 1
- 102000004506 Blood Proteins Human genes 0.000 description 1
- 108010017384 Blood Proteins Proteins 0.000 description 1
- 208000009043 Chemical Burns Diseases 0.000 description 1
- 208000018380 Chemical injury Diseases 0.000 description 1
- 241000700112 Chinchilla Species 0.000 description 1
- 208000023329 Gun shot wound Diseases 0.000 description 1
- 241000594011 Leuciscus leuciscus Species 0.000 description 1
- 241000700159 Rattus Species 0.000 description 1
- 241000700157 Rattus norvegicus Species 0.000 description 1
- 229910021536 Zeolite Inorganic materials 0.000 description 1
- 210000000683 abdominal cavity Anatomy 0.000 description 1
- 230000004913 activation Effects 0.000 description 1
- 210000001367 artery Anatomy 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 230000036760 body temperature Effects 0.000 description 1
- 230000015271 coagulation Effects 0.000 description 1
- 238000005345 coagulation Methods 0.000 description 1
- 239000012141 concentrate Substances 0.000 description 1
- 238000012790 confirmation Methods 0.000 description 1
- HNPSIPDUKPIQMN-UHFFFAOYSA-N dioxosilane;oxo(oxoalumanyloxy)alumane Chemical compound O=[Si]=O.O=[Al]O[Al]=O HNPSIPDUKPIQMN-UHFFFAOYSA-N 0.000 description 1
- 208000009190 disseminated intravascular coagulation Diseases 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 230000017074 necrotic cell death Effects 0.000 description 1
- 206010033675 panniculitis Diseases 0.000 description 1
- 210000004738 parenchymal cell Anatomy 0.000 description 1
- 210000000505 parietal peritoneum Anatomy 0.000 description 1
- 230000008092 positive effect Effects 0.000 description 1
- 239000003805 procoagulant Substances 0.000 description 1
- 210000002254 renal artery Anatomy 0.000 description 1
- 239000002356 single layer Substances 0.000 description 1
- 210000003491 skin Anatomy 0.000 description 1
- 238000001179 sorption measurement Methods 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 239000003860 topical agent Substances 0.000 description 1
- 230000000472 traumatic effect Effects 0.000 description 1
- 210000000689 upper leg Anatomy 0.000 description 1
- 210000001835 viscera Anatomy 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
- 239000010457 zeolite Substances 0.000 description 1
Abstract
Способ остановки кровотечения из сосудов разного типа путем аппликации на место сосудистого дефекта средства местного назначения, а именно гемостатического материала, включающего хитозан, формированием многослойной повязки с последующим добавлением давления на нее при прижимании повязки на раневую поверхность. Хитозан, который используют в составе гемостатического материала, применяют в форме геля с концентрацией действующего вещества от 0,5 % до 5 % и молекулярной массой хитозана от 100 до 900 кДа. Многослойную повязку формируют толщиной от 0,5 до 5 см, осуществляя нанесения геля хитозана на основу, в частности марлю, целлюлозу, коллаген с последующим высушиванием, или с использованием золь-гель метода, стимулированного замораживанием (freeze-gelation). После добавления давления на многослойную повязку при ее прижимании к ране в течение не менее пяти минут осуществляют ее фиксацию, проводя тугое бинтование ею, или продолжают постоянное прижатие многослойной повязки до полной остановки кровотечения.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| UAU201508621U UA105516U (ru) | 2015-09-07 | 2015-09-07 | Способ остановки кровотечения из сосудов разного типа |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| UAU201508621U UA105516U (ru) | 2015-09-07 | 2015-09-07 | Способ остановки кровотечения из сосудов разного типа |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA105516U true UA105516U (ru) | 2016-03-25 |
Family
ID=55798813
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAU201508621U UA105516U (ru) | 2015-09-07 | 2015-09-07 | Способ остановки кровотечения из сосудов разного типа |
Country Status (1)
| Country | Link |
|---|---|
| UA (1) | UA105516U (ru) |
-
2015
- 2015-09-07 UA UAU201508621U patent/UA105516U/ru unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US10159762B2 (en) | Hemostatic compositions and dressings for bleeding | |
| US10314937B2 (en) | Biocompatible hemostatic product and preparation method thereof | |
| Bilgili et al. | Hemostatic efficacy of Ankaferd Blood Stopper® in a swine bleeding model | |
| Pusateri et al. | Advanced hemostatic dressing development program: animal model selection criteria and results of a study of nine hemostatic dressings in a model of severe large venous hemorrhage and hepatic injury in Swine | |
| US20220072192A1 (en) | Biocompatible carboxymethylcellulose matrix (bcm) for hemostasis, tissue barrier, wound healing, and cosmetology | |
| Takagi et al. | Two-layer sheet of gelatin: A new topical hemostatic agent | |
| JP2002515300A (ja) | 止血サンドウィッチ包帯 | |
| CN106581736B (zh) | 原料为娃娃鱼体表黏液的医用粘合剂及制备方法 | |
| CN101606949A (zh) | 一种以高比表面积微孔淀粉为主要原料的快速止血剂及其制备工艺 | |
| CN109689069A (zh) | 具有止血作用的伤口覆盖物及其产生方法 | |
| Pavliuk et al. | Characteristics of structured medical hemostatic sponges as a medical devices for stop bleeding and for close the wound | |
| Cannon et al. | Rate of epithelial regeneration: a clinical method of measurement, and the effect of various agents recommended in the treatment of burns | |
| UA105516U (ru) | Способ остановки кровотечения из сосудов разного типа | |
| CN109731128A (zh) | 一种可吸收降解的生物相容性止血材料及其制备方法 | |
| CN204723126U (zh) | 经皮冠状动脉介入治疗术后用止血带 | |
| RU2436527C1 (ru) | Способ многоэтапного хирургического лечения массивного внутреннего кровотечения из паренхиматозных органов при политравмах | |
| Fan et al. | Haemostatic efficacy of an ethyl-2-cyanoacrylate-based aerosol in combination with tourniquet application in a large wound model with an arterial injury | |
| RU2796161C1 (ru) | Гемостатичекий гель однократного местного применения | |
| CN110478510A (zh) | 一种急速止血绷带 | |
| CN110478513A (zh) | 一种壳聚糖复合敷料 | |
| Tucker et al. | Chitosan‐based agent use for hemostasis after cryptorchidectomy in a horse | |
| RU2806364C1 (ru) | Способ получения гемостатического средства на основе хитозана | |
| Dikme et al. | The effect of application of local oxidised cellulose powder on hemostasis time in a rat model with femoral artery bleeding | |
| RU2808182C1 (ru) | Способ лечения ожогов у животных | |
| CN114269350A (zh) | 局部止血组合物 |