TWM559152U - Breast sculpture filling containing high biocompatible micro-stents for minimally invasive medical cosmetic surgery - Google Patents

Breast sculpture filling containing high biocompatible micro-stents for minimally invasive medical cosmetic surgery Download PDF

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TWM559152U
TWM559152U TW106215384U TW106215384U TWM559152U TW M559152 U TWM559152 U TW M559152U TW 106215384 U TW106215384 U TW 106215384U TW 106215384 U TW106215384 U TW 106215384U TW M559152 U TWM559152 U TW M559152U
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Taiwan
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sculpture
breast
filling
body structure
micro
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TW106215384U
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Chinese (zh)
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Ching-Cheng Huang
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Parsd Medical Science And Technology Co Ltd
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Abstract

本創作揭示一種用於醫學美容微創含高生物相容性微支架之乳房雕塑填補物,其中包含一填補物主體結構;複數個設置於該填補物主體結構並貫穿該填補物主體結構之通孔;以及分布在該通孔周圍複數個高生物相容性微支架;其中該高生物相容性微支架具有一空隙空間,該空隙空間透過該高生物相容性微支架貫通該填補物主體結構。該填補物主體結構的中心區域進一步設置有中心突起結構,以及複數個設置並貫穿於該中心突起結構之中心突起結構通孔,該高生物相容性微支架具有一空隙空間,該空隙空間透過該高生物相容性微支架貫通該填補物主體結構。 The present invention discloses a breast sculpture filling for medical cosmetic minimally invasive micro-support with high biocompatibility, which comprises a filling body structure; a plurality of the main structure of the filling body and extending through the body structure of the filling body a plurality of highly biocompatible micro-scaffolds distributed around the through-hole; wherein the highly biocompatible micro-stent has a void space through the high biocompatible micro-stent through the filler body structure. The central region of the body structure of the filler is further provided with a central protrusion structure, and a plurality of through holes penetrating through the central protrusion structure of the center protrusion structure, the high biocompatibility micro-frame has a void space, and the space is transparent The highly biocompatible microstent extends through the filler body structure.

Description

用於醫學美容微創含高生物相容性微支架之乳房雕塑填補物 Used for medical cosmetic minimally invasive breast sculpture filling with high biocompatibility micro-scaffold

本創作係有關於一種用於醫學美容微創含高生物相容性微支架之乳房雕塑填補物。特別是本創作骨填補物包含有一種高生物相容性微支架結構,可以用於齒科、骨科、醫美顏面整型修飾整形外科重建修復延緩降解之骨填補物。 This creation is about a breast sculpture filling for medical cosmetic minimally invasive micro-stents with high biocompatibility. In particular, the bone filling of the present invention comprises a high biocompatibility micro-scaffold structure, which can be used for dental, orthopedic, medical cosmetic and facial plastic surgery to reconstruct and repair the bone filling material for delaying degradation.

本創作係指一種用於醫學美容微創含高生物相容性微支架之乳房雕塑填補物,尤指一種可以用於齒科、骨科、醫美顏面整型修飾整形外科重建修復延緩降解之乳房雕塑填補物。在臨床手術中,常需對組織缺損進行修補,然而自體移植的有限來源,而異體與異種移植則具高傳染風險。因此,現今有越來越多不同的有機、無機、金屬材料應用於組織工程。此外為了避免二次手術,使用生物可降解材料有其必要性。目前所使用之不同材料皆有其優缺點,為了解決醫療上不同問題,開發新的功能性複合材料仍是研究重點之一。組織工程是連接工程和生物學的一個跨學科領域。組織工程發展生物基材,它可以修復,恢復或改善組織之功能。其中組織工程涉及三個主要策略:利用體外細胞或細胞替代物,取代有限的組織功能;誘導組織生成,例如生長因子(growth factors)的利用;發展生物支架 (scaffold)有利於組織修補與再生。因此,支架的發展關鍵因素是模仿細胞外基質(ECM)的物理和生物功能設計而成之生長環境,是在細胞培養基材重要發展技術。應用於微創外科手術中,不同形式的缺損以不同修補方式,開發不同功能性支架應用於臨床是必要的。申請人有鑑於此,乃秉持從事生物醫學工程及材料之多年經驗,經不斷研究、實驗,遂研發創作一種用於重建修復高生物相容性微支架結構之醫療器材及生物醫學材料,祈使供應用於臨床使用。 This creation refers to a breast sculpture filling for medical cosmetic minimally invasive micro-stent with high biocompatibility, especially a kind of dental surgery, orthopedics, medical beauty, face modification, plastic surgery reconstruction, delayed degradation of breast Sculpture fills. In clinical surgery, it is often necessary to repair tissue defects, but the limited source of autologous transplantation, while allogeneic and xenotransplantation have a high risk of infection. Therefore, more and more different organic, inorganic, and metallic materials are used in tissue engineering today. In addition, in order to avoid secondary surgery, it is necessary to use biodegradable materials. The different materials currently used have their advantages and disadvantages. In order to solve different medical problems, the development of new functional composite materials is still one of the research priorities. Tissue engineering is an interdisciplinary field that connects engineering and biology. Tissue engineering develops biological substrates that can repair, restore or improve the function of tissues. Among them, tissue engineering involves three main strategies: using in vitro cells or cell substitutes to replace limited tissue functions; inducing tissue production, such as the utilization of growth factors; developing biological scaffolds (scaffold) is good for tissue repair and regeneration. Therefore, the key factor in the development of scaffolds is the growth environment designed by mimicking the physical and biological functions of extracellular matrix (ECM), which is an important development technique in cell culture media. In minimally invasive surgery, different forms of defects are differently repaired, and it is necessary to develop different functional stents for clinical application. In view of this, the applicant has been engaged in biomedical engineering and materials for many years of experience, through continuous research and experimentation, and has developed a medical device and biomedical materials for reconstruction and repair of highly biocompatible micro-scaffold structures. Supplied for clinical use.

本創作係提供一種用於醫學美容微創含高生物相容性微支架之乳房雕塑填補物。特別是本創作涉及含高生物相容性微支架結構之醫療器材及生物醫學材料,其中該乳房雕塑填補物包含一填補物主體結構;複數個設置於該填補物主體結構並貫穿該填補物主體結構之通孔;以及分布在該通孔周圍複數個高生物相容性微支架;其中該高生物相容性微支架具有一空隙空間,該空隙空間透過該高生物相容性微支架貫通該填補物主體結構。優選地,該填補物主體結構的中心區域進一步設置有中心突起結構,以及複數個設置並貫穿於該中心突起結構之中心突起結構通孔,該高生物相容性微支架具有一空隙空間,該空隙空間透過該高生物相容性微支架貫通該填補物主體結構。優選地,該高生物相容性微支架係由一選自由膠原蛋白,膠原胜肽,明膠, 海藻酸鈉,纖維素,多醣體,甲殼素,聚乳酸,聚乳酸酯及其組合之生物可分解高分子所組成。 This creation provides a breast sculpture fill for medical cosmetic minimally invasive micro-stents with high biocompatibility. In particular, the present invention relates to a medical device and a biomedical material comprising a highly biocompatible micro-scaffold structure, wherein the breast sculpture filler comprises a filler body structure; a plurality of the body structure disposed in the filler body and extending through the body of the filler a through hole of the structure; and a plurality of highly biocompatible micro-stents distributed around the through-hole; wherein the highly biocompatible micro-stent has a void space through which the high-biocompatible micro-stent passes Fill the main structure of the object. Preferably, the central region of the filler body structure is further provided with a central protrusion structure, and a plurality of central protruding structure through holes disposed through the central protrusion structure, the high biocompatibility micro-bracket having a void space, The void space penetrates the filler body structure through the highly biocompatible microstent. Preferably, the highly biocompatible microscaffold is selected from the group consisting of collagen, collagen peptide, gelatin, A biodegradable polymer composed of sodium alginate, cellulose, polysaccharide, chitin, polylactic acid, polylactic acid ester and combinations thereof.

優選地,該高生物相容性微支架係由一選自由膠原蛋白,膠原胜肽,明膠及其組合之生物可分解高分子所組成。 Preferably, the highly biocompatible microscaffold consists of a biodegradable polymer selected from the group consisting of collagen, collagen peptide, gelatin and combinations thereof.

優選地,該高生物相容性微支架為一種利用親水性震動切削動物真皮及超臨界二氧化碳脫脂,酶處理所得的膠原蛋白結構體。 Preferably, the highly biocompatible micro-scaffold is a collagen structure obtained by enzymatically treating the dermis of the animal and the supercritical carbon dioxide degreasing by hydrophilic vibration.

優選地,該填補物主體結構係由一選自由膠原蛋白,膠原胜肽,明膠,海藻酸鈉,纖維素,多醣體,甲殼素,聚乳酸,聚乳酸酯及其組合之生物可分解高分子所組成。 Preferably, the filler body structure is biodegradable high from a selected from the group consisting of collagen, collagen peptide, gelatin, sodium alginate, cellulose, polysaccharide, chitin, polylactic acid, polylactic acid and combinations thereof. Made up of molecules.

1,1’‧‧‧乳房雕塑填補物 1,1’‧‧‧ Breast Sculpture Filler

10,10’‧‧‧高生物相容性微支架 10,10’‧‧‧High biocompatible micro scaffold

15,15’‧‧‧空隙空間 15,15’‧‧‧ void space

20,20’‧‧‧填補物主體結構 20,20’‧‧‧Fat main structure

30,30’‧‧‧通孔 30,30’‧‧‧through hole

35’‧‧‧中心突起結構通孔 35’‧‧‧Center protruding structure through hole

第1圖係為本創作含高生物相容性微支架之乳房雕塑填補物示意圖。 The first picture is a schematic diagram of a breast sculpture filling with a high biocompatibility micro-stent.

第2圖係為本創作之具有中心突起結構之乳房雕塑填補物示意圖。 The second picture is a schematic diagram of the breast sculpture filling with the central protruding structure of the creation.

第1實施例-含高生物相容性微支架之乳房雕塑填補物 First Embodiment - Breast Sculpture Filler with High Biocompatibility Microscaffold

本創作用於醫學美容微創含高生物相容性微支架之乳房雕塑填補之第1實施例將參閱第1圖加以說明。本創作用於醫學美容微創含高生物相容性微支架之乳房雕塑填補物,其中該乳房雕塑填補物包含一填補物主體結構20;複數個設置於該填補物主體結構20並貫穿該填補物主體結構20之通孔30;以及分布在該通孔30周圍複數個高生物相容性微支架10;其中該高生物相容性微支架10具有一空隙空間15,該空隙空間15透過該高生物相 容性微支架10貫通該填補物主體結構20。優選地,該高生物相容性微支架係由一選自由膠原蛋白、膠原胜肽、海藻酸鈉,纖維素,多醣體,甲殼素,聚乳酸,聚乳酸酯及其組合之生物可分解高分子所組成。優選地,該高生物相容性微支架係由一選自由膠原蛋白、膠原胜肽及其組合之生物可分解高分子所組成。優選地,該高生物相容性微支架為一種利用親水性震動切削動物真皮及超臨界二氧化碳脫脂,酶處理所得的膠原蛋白結構體。優選地,該填補物主體結構係由一選自由膠原蛋白,膠原胜肽,明膠,海藻酸鈉,纖維素,多醣體,甲殼素,聚乳酸,聚乳酸酯及其組合之生物可分解高分子所組成。 The first embodiment of the present invention for the medical cosmetic minimally invasive breast sculpture filling with a highly biocompatible microscaffold will be described with reference to FIG. The invention is used for medical cosmetic minimally invasive breast sculpture filling with high biocompatibility micro-scaffold, wherein the breast sculpture filling comprises a filling body structure 20; a plurality of filling body structures 20 are disposed and penetrated through the filling a through hole 30 of the main body structure 20; and a plurality of highly biocompatible micro-scaffolds 10 distributed around the through-hole 30; wherein the highly biocompatible micro-stent 10 has a void space 15 through which the void space 15 High biological phase The capacitive microstent 10 extends through the filler body structure 20. Preferably, the highly biocompatible microscaffold is biodegradable from a substance selected from the group consisting of collagen, collagen peptide, sodium alginate, cellulose, polysaccharide, chitin, polylactic acid, polylactic acid ester and combinations thereof. Composition of polymers. Preferably, the highly biocompatible microscaffold consists of a biodegradable polymer selected from the group consisting of collagen, collagen peptides, and combinations thereof. Preferably, the highly biocompatible micro-scaffold is a collagen structure obtained by enzymatically treating the dermis of the animal and the supercritical carbon dioxide degreasing by hydrophilic vibration. Preferably, the filler body structure is biodegradable high from a selected from the group consisting of collagen, collagen peptide, gelatin, sodium alginate, cellulose, polysaccharide, chitin, polylactic acid, polylactic acid and combinations thereof. Made up of molecules.

第2實施例-一種具有中心突起結構用於醫學美容微創含高生物相容性微支架之乳房雕塑填補物 Second Embodiment - a breast sculpture filling with a central protrusion structure for medical cosmetic minimally invasive micro-stent with high biocompatibility

本創作用於醫學美容微創含高生物相容性微支架之乳房雕塑填補物之第2實施例將參閱第2圖加以說明。本創作具有中心突起結構用於用於醫學美容微創含高生物相容性微支架之乳房雕塑填補物1’,其中該乳房雕塑填補物包含一填補物主體結構20’;複數個設置於該填補物主體結構20並貫穿該填補物主體結構20’之通孔30’;以及分布在該通孔30周圍複數個高生物相容性微支架10’;其中該高生物相容性微支架10’具有一空隙空間15’,該空隙空間15透過該高生物相容性微支架10’貫通該填補物主體結構20’。本實施例之創作在該填補物主體結構的中心區域進一步設置有中心突起結構25’,以及複數個設置並貫穿於該中心突起結構之中心突 構通孔35’,該高生物相容性微支架具有一空隙空間15’,該空隙空間15’透過該高生物相容性微支架10’貫通該填補物主體結構20’。優選地,該高生物相容性微支架係由一選自由膠原蛋白,膠原胜肽,明膠,海藻酸鈉,纖維素,多醣體,甲殼素,聚乳酸,聚乳酸酯及其組合之生物可分解高分子所組成。優選地,該高生物相容性微支架係由一選自由膠原蛋白、膠原胜肽及其組合之生物可分解高分子所組成。更優選地,該高生物相容性微支架為一種利用親水性震動切削動物真皮及超臨界二氧化碳脫脂,酶處理所得的膠原蛋白結構體。優選地,該填補物主體結構係由一選自由膠原蛋白,膠原胜肽,明膠,海藻酸鈉,纖維素,多醣體,甲殼素,聚乳酸,聚乳酸酯及其組合之生物可分解高分子所組成。 The second embodiment of the present invention for use in medical cosmetic minimally invasive breast sculpture fillings containing highly biocompatible micro-scaffolds will be described with reference to FIG. The present invention has a central protruding structure for medical cosmetic minimally invasive breast sculpture filling 1' containing a highly biocompatible micro-stent, wherein the breast sculpture filling comprises a filling body structure 20'; a filler body structure 20 and a through hole 30 ′ extending through the filler body structure 20 ′; and a plurality of highly biocompatible micro-frames 10 ′ distributed around the through-hole 30 ; wherein the highly biocompatible micro-frame 10 'Having a void space 15', the void space 15 penetrates the filler body structure 20' through the highly biocompatible micro-frame 10'. The creation of this embodiment is further provided with a central protrusion structure 25' in the central region of the filler body structure, and a plurality of central protrusions disposed and penetrating through the center protrusion structure A through hole 35' is formed which has a void space 15' which penetrates the filler body structure 20' through the highly biocompatible micro-frame 10'. Preferably, the highly biocompatible microscaffold is composed of an organism selected from the group consisting of collagen, collagen peptide, gelatin, sodium alginate, cellulose, polysaccharide, chitin, polylactic acid, polylactate and combinations thereof. It can be composed of decomposable polymers. Preferably, the highly biocompatible microscaffold consists of a biodegradable polymer selected from the group consisting of collagen, collagen peptides, and combinations thereof. More preferably, the highly biocompatible microscaffold is a collagen structure obtained by hydrolyzing animal dermis and supercritical carbon dioxide degreasing and enzymatic treatment. Preferably, the filler body structure is biodegradable high from a selected from the group consisting of collagen, collagen peptide, gelatin, sodium alginate, cellulose, polysaccharide, chitin, polylactic acid, polylactic acid and combinations thereof. Made up of molecules.

上所述者,僅為本創作之較佳實施例,當不能以此限定本創作實施之範圍,即大凡依本創作申請專利範圍及新型說明書內容所作之等效變化與修飾,皆應仍屬本創作專利涵蓋之範圍內。綜觀上述,本創作之構造特徵確實具有實用價值及進步性,以其整體結構而言,誠已符合專利法之法定要件,爰依法提出新型專利申請。 The above description is only a preferred embodiment of the present invention. When it is not possible to limit the scope of the creation of the present invention, the equivalent changes and modifications made by the applicant in accordance with the scope of the patent application and the contents of the new manual should remain This creative patent covers the scope. Looking at the above, the structural features of this creation do have practical value and progressiveness. In terms of its overall structure, Cheng has already complied with the statutory requirements of the Patent Law and has filed a new type of patent application according to law.

Claims (6)

一種用於醫學美容微創含高生物相容性微支架之乳房雕塑填補物,包含一填補物主體結構;複數個設置於該填補物主體結構並貫穿該填補物主體結構之通孔;以及分布在該通孔周圍複數個高生物相容性微支架;其中該高生物相容性微支架具有一空隙空間,該空隙空間透過該高生物相容性微支架貫通該填補物主體結構。 A breast sculpture filling for medically invasive minimally invasive micro-support with high biocompatibility, comprising a filler body structure; a plurality of through holes disposed in the body structure of the filler and extending through the body structure of the filler; and distribution A plurality of highly biocompatible micro-scaffolds are disposed around the through-hole; wherein the highly biocompatible micro-stent has a void space through the high biocompatible micro-stent through the filler body structure. 如申請專利範圍第1項所述之乳房雕塑填補物,其中該填補物主體結構的中心區域進一步設置有中心突起結構,以及複數個設置並貫穿於該中心突起結構之中心突起結構通孔,該高生物相容性微支架具有一空隙空間,該空隙空間透過該高生物相容性微支架貫通該填補物主體結構。 The breast sculpture filler according to claim 1, wherein a central region of the filler body structure is further provided with a central protrusion structure, and a plurality of through holes penetrating through the central protrusion structure of the center protrusion structure, The highly biocompatible microscaffold has a void space that penetrates the filler body structure through the highly biocompatible microstent. 如申請專利範圍第1項所述之乳房雕塑填補物,其中該高生物相容性微支架係由一選自由膠原蛋白,膠原胜肽,明膠,海藻酸鈉,纖維素,多醣體,甲殼素,聚乳酸,聚乳酸酯及其組合之生物可分解高分子所組成。 The breast sculpture filling according to claim 1, wherein the highly biocompatible microscaffold is selected from the group consisting of collagen, collagen peptide, gelatin, sodium alginate, cellulose, polysaccharide, chitin. Polylactic acid, polylactic acid ester and a combination thereof are composed of biodegradable polymers. 如申請專利範圍第3項所述之乳房雕塑填補物,其中該高生物相容性微支架係由一選自由膠原蛋白,膠原胜肽,明膠及其組合之生物可分解高分子所組成。 The breast sculpture filling of claim 3, wherein the highly biocompatible microscaffold is composed of a biodegradable polymer selected from the group consisting of collagen, collagen peptide, gelatin and combinations thereof. 如申請專利範圍第4項所述之乳房雕塑填補物,其中該高生物相容性微支 架為一種利用親水性震動切削動物真皮及超臨界二氧化碳脫脂,酶處理所得的膠原蛋白結構體。 The breast sculpture filling of claim 4, wherein the high biocompatibility microtubule The rack is a collagen structure obtained by using hydrophilic vibration to cut animal dermis and supercritical carbon dioxide degreasing and enzymatic treatment. 如申請專利範圍第2項所述之乳房雕塑填補物,其中該填補物主體結構係由一選自由膠原蛋白,膠原胜肽,明膠,海藻酸鈉,纖維素,多醣體,甲殼素,聚乳酸,聚乳酸酯及其組合之生物可分解高分子所組成。 The breast sculpture filling according to claim 2, wherein the filling body structure is selected from the group consisting of collagen, collagen peptide, gelatin, sodium alginate, cellulose, polysaccharide, chitin, polylactic acid. Polylactic acid ester and a combination thereof are composed of biodegradable polymers.
TW106215384U 2017-10-19 2017-10-19 Breast sculpture filling containing high biocompatible micro-stents for minimally invasive medical cosmetic surgery TWM559152U (en)

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