TWI902659B - Ｐｅｄｆ衍生之短肽在肌腱癒合中的應用 - Google Patents

Ｐｅｄｆ衍生之短肽在肌腱癒合中的應用

Info

Publication number
TWI902659B
TWI902659B TW108112195A TW108112195A TWI902659B TW I902659 B TWI902659 B TW I902659B TW 108112195 A TW108112195 A TW 108112195A TW 108112195 A TW108112195 A TW 108112195A TW I902659 B TWI902659 B TW I902659B
Authority
TW
Taiwan
Prior art keywords
tendon
mer
pedf
pdsp
derived
Prior art date
Application number
TW108112195A
Other languages
English (en)
Chinese (zh)
Other versions
TW202010513A (zh
Inventor
文機 李
李元銘
曹友平
何宗權
Original Assignee
全福生物科技股份有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 全福生物科技股份有限公司 filed Critical 全福生物科技股份有限公司
Publication of TW202010513A publication Critical patent/TW202010513A/zh
Application granted granted Critical
Publication of TWI902659B publication Critical patent/TWI902659B/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biomedical Technology (AREA)
  • Dermatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
TW108112195A 2018-04-08 2019-04-08 Ｐｅｄｆ衍生之短肽在肌腱癒合中的應用 TWI902659B (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862654466P 2018-04-08 2018-04-08
US62/654,466 2018-04-08

Publications (2)

Publication Number Publication Date
TW202010513A TW202010513A (zh) 2020-03-16
TWI902659B true TWI902659B (zh) 2025-11-01

Family

ID=68163751

Family Applications (1)

Application Number Title Priority Date Filing Date
TW108112195A TWI902659B (zh) 2018-04-08 2019-04-08 Ｐｅｄｆ衍生之短肽在肌腱癒合中的應用

Country Status (10)

Country Link
US (1) US20210244791A1 (enExample)
EP (1) EP3761959A4 (enExample)
JP (2) JP7481261B2 (enExample)
KR (1) KR20200142521A (enExample)
CN (1) CN113038929A (enExample)
AU (2) AU2019251091A1 (enExample)
EA (1) EA202092368A1 (enExample)
IL (1) IL277689B2 (enExample)
TW (1) TWI902659B (enExample)
WO (1) WO2019199661A1 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL277689B2 (en) * 2018-04-08 2024-12-01 Brim Biotechnology Inc Application of pedf-derived short peptides in tendon healing

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUE035655T2 (en) * 2005-08-05 2018-05-28 Araim Pharmaceuticals Inc Tissue protective peptides and their use
WO2007095350A2 (en) * 2006-02-15 2007-08-23 Yale University Compositions and methods for use of pigment epithelial derived factor (pedf) peptide fragments
ES2329636B2 (es) * 2006-02-17 2010-07-26 Universitat De Valencia, Estudi General (Participa Con El 70%) Uso del factor pedf para inducir la auto-renovacion de celulas madre.
EP2508196B1 (en) * 2011-03-23 2018-09-26 Mackay Memorial Hospital Use of PEDF-derived polypeptides for promoting stem cells proliferation and wound healing
TWI491616B (zh) * 2012-08-09 2015-07-11 Mackay Memorial Hospital 色素上皮衍生因子衍生之多胜肽於促進肌肉或肌腱再生或動脈血管生成之用途
KR101801198B1 (ko) * 2012-08-09 2017-11-24 맥케이 메모리얼 호스피탈 근육 또는 힘줄 재생 또는 동맥형성을 촉진하기 위해 사용되는 pedf-유도 폴리펩티드의 용도
EA037698B1 (ru) * 2016-10-07 2021-05-12 Брим Байотекнолоджи, Инк. Композиции, содержащие короткие пептиды, полученные из pedf, и их применение
IL277689B2 (en) * 2018-04-08 2024-12-01 Brim Biotechnology Inc Application of pedf-derived short peptides in tendon healing

Also Published As

Publication number Publication date
CN113038929A (zh) 2021-06-25
WO2019199661A1 (en) 2019-10-17
EA202092368A1 (ru) 2021-01-18
IL277689A (en) 2020-11-30
EP3761959A1 (en) 2021-01-13
JP2021521113A (ja) 2021-08-26
AU2025201569A1 (en) 2025-05-22
JP7481261B2 (ja) 2024-05-10
IL277689B2 (en) 2024-12-01
EP3761959A4 (en) 2022-03-02
KR20200142521A (ko) 2020-12-22
US20210244791A1 (en) 2021-08-12
IL277689B1 (en) 2024-08-01
JP2024054273A (ja) 2024-04-16
AU2019251091A1 (en) 2020-11-26
TW202010513A (zh) 2020-03-16

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