TWI856048B - 多聚體ｔ細胞調節多肽及其使用方法 - Google Patents
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/20011—Papillomaviridae
- C12N2710/20033—Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
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- Pharmacology & Pharmacy (AREA)
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- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
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- Biophysics (AREA)
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- Developmental Biology & Embryology (AREA)
- Gynecology & Obstetrics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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| US201862782205P | 2018-12-19 | 2018-12-19 | |
| US62/782,205 | 2018-12-19 | ||
| US201962814707P | 2019-03-06 | 2019-03-06 | |
| US62/814,707 | 2019-03-06 |
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| TW202031680A TW202031680A (zh) | 2020-09-01 |
| TWI856048B true TWI856048B (zh) | 2024-09-21 |
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| TW108146527A TWI856048B (zh) | 2018-12-19 | 2019-12-18 | 多聚體ｔ細胞調節多肽及其使用方法 |
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| EP (1) | EP3897746A4 (enExample) |
| JP (2) | JP7481342B2 (enExample) |
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| MX (1) | MX2021007479A (enExample) |
| TW (1) | TWI856048B (enExample) |
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| ES2973548T3 (es) | 2016-12-22 | 2024-06-20 | Cue Biopharma Inc | Polipéptidos multiméricos moduladores de linfocitos T y métodos para su uso |
| US20200010528A1 (en) | 2017-03-15 | 2020-01-09 | Cue Biopharma, Inc. | Methods for modulating an immune response |
| JP2020534352A (ja) | 2017-09-07 | 2020-11-26 | キュー バイオファーマ，インコーポレーテッド | コンジュゲーション部位を有するｔ細胞調節多量体ポリペプチド及びその使用方法 |
| MX2021007479A (es) * | 2018-12-19 | 2021-09-23 | Cue Biopharma Inc | Polipeptidos multimericos moduladores de linfocitos t y metodos de uso de estos. |
| WO2021127487A2 (en) | 2019-12-20 | 2021-06-24 | Regeneron Pharmaceuticals, Inc. | Novel il2 agonists and methods of use thereof |
| WO2021231376A2 (en) | 2020-05-12 | 2021-11-18 | Cue Biopharma, Inc. | Multimeric t-cell modulatory polypeptides and methods of use thereof |
| EP4210736A4 (en) * | 2020-09-09 | 2024-10-23 | Cue Biopharma, Inc. | MULTIMERIC POLYPEPTIDES MODULATING MHC CLASS II T CELLS AND METHODS OF USE THEREOF |
| WO2022056014A1 (en) * | 2020-09-09 | 2022-03-17 | Cue Biopharma, Inc. | Mhc class ii t-cell modulatory multimeric polypeptides for treating type 1 diabetes mellitus (t1d) and methods of use thereof |
| TW202317623A (zh) | 2021-06-14 | 2023-05-01 | 美商再生元醫藥公司 | 基於il2之治療劑及其使用方法 |
| US20260097105A1 (en) * | 2022-09-30 | 2026-04-09 | The Children's Hospital Of Philadelphia | Systems, formulations and methods for generating universal peptide/mhc complexes with engineered disulfide connecting the heavy and light chains |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015195531A2 (en) * | 2014-06-18 | 2015-12-23 | Albert Einstein College Of Medicine, Inc. | Syntac polypeptides and uses thereof |
| WO2017008844A1 (en) * | 2015-07-14 | 2017-01-19 | Biontech Ag | Peptide mimotopes of the cd3 t-cell co-receptor epsilon chain and uses thereof |
| WO2017201210A1 (en) * | 2016-05-18 | 2017-11-23 | Cue Biopharma, Inc. | T-cell modulatory multimeric polypeptides and methods of use thereof |
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| DK3186283T3 (da) * | 2014-08-29 | 2020-03-02 | Hoffmann La Roche | Kombinationsbehandling med tumormålrettede IL-2- immuncytokinervarianter og antistoffer mod humant PD-L1 |
| ES2973548T3 (es) * | 2016-12-22 | 2024-06-20 | Cue Biopharma Inc | Polipéptidos multiméricos moduladores de linfocitos T y métodos para su uso |
| MX2021007479A (es) * | 2018-12-19 | 2021-09-23 | Cue Biopharma Inc | Polipeptidos multimericos moduladores de linfocitos t y metodos de uso de estos. |
| KR20220015382A (ko) * | 2019-05-29 | 2022-02-08 | 큐 바이오파마, 인크. | 다량체 t-세포 조절 폴리펩타이드 및 이의 사용 방법 |
| JP2022536581A (ja) * | 2019-06-19 | 2022-08-18 | キュー バイオファーマ， インコーポレイテッド | 多量体ｔ細胞調節性ポリペプチド及びその使用方法 |
| CA3146917A1 (en) * | 2019-10-23 | 2021-04-29 | Anish SURI | T-cell modulatory chimeric molecules and methods of use thereof |
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2019
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- 2019-12-18 CN CN201980080704.5A patent/CN113286621A/zh active Pending
- 2019-12-18 KR KR1020217017809A patent/KR20210104700A/ko not_active Ceased
- 2019-12-18 TW TW108146527A patent/TWI856048B/zh active
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2021
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015195531A2 (en) * | 2014-06-18 | 2015-12-23 | Albert Einstein College Of Medicine, Inc. | Syntac polypeptides and uses thereof |
| WO2017008844A1 (en) * | 2015-07-14 | 2017-01-19 | Biontech Ag | Peptide mimotopes of the cd3 t-cell co-receptor epsilon chain and uses thereof |
| WO2017201210A1 (en) * | 2016-05-18 | 2017-11-23 | Cue Biopharma, Inc. | T-cell modulatory multimeric polypeptides and methods of use thereof |
Also Published As
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| IL282250A (en) | 2021-05-31 |
| KR20210104700A (ko) | 2021-08-25 |
| JP7481342B2 (ja) | 2024-05-10 |
| EP3897746A1 (en) | 2021-10-27 |
| MX2021007479A (es) | 2021-09-23 |
| US20250092113A1 (en) | 2025-03-20 |
| WO2020132138A1 (en) | 2020-06-25 |
| CN113286621A (zh) | 2021-08-20 |
| AU2019401183A1 (en) | 2021-08-12 |
| US20220389079A1 (en) | 2022-12-08 |
| BR112021011838A2 (pt) | 2021-08-31 |
| EP3897746A4 (en) | 2022-10-26 |
| CA3113096A1 (en) | 2020-06-25 |
| JP2024105344A (ja) | 2024-08-06 |
| JP2022515331A (ja) | 2022-02-18 |
| TW202031680A (zh) | 2020-09-01 |
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