TWI821544B - Hydrogen-dissolved water generating device and hydrogen-dissolved water generating method - Google Patents

Abstract

The present disclosure provides a technology capable of controlling generation of hydrogen-dissolved water based on hydrogen delivered to a patient's body in hemodialysis treatment using hydrogen-dissolved water. The hydrogen-dissolved water generating device (1) is a device for generating hydrogen-dissolved water obtained by dissolving hydrogen into water. The hydrogen-dissolved water generating device (1) includes: a hydrogen water generating unit (3) that is configured to generate hydrogen-dissolved water; a detection unit (12) that is configured to detect hydrogen contained in the breath of a patient (H) undergoing dialysis using a dialysate prepared with hydrogen-dissolved water; and a control unit (13) that is configured to control the hydrogen water generating unit (3) according to a detection result of the detection unit (12).

Description

Dissolved hydrogen water generating device and hydrogen dissolved water generating method

The present invention relates to a hydrogen-dissolved water generating device and a hydrogen-dissolved water generating method for generating hydrogen-dissolved water used in preparation of dialysate.

In hemodialysis treatment, dialysate prepared by using hydrogen-dissolved water dissolved in hydrogen helps reduce oxidative stress in patients, and has attracted much attention in recent years (see, for example, Patent Document 1).

Prior technical documents

patent documents

Patent Document 1: JP Patent Application Publication No. 5840248

In view of this, our inventors devoted themselves to further research, and began to carry out research and development and improvement, hoping to solve the above problems with a better invention, and after continuous testing and modification, the present invention came out.

(The problem to be solved by the invention)

In dialysis treatment using the device disclosed in the above-mentioned Patent Document 1, it is unclear to what extent hydrogen is delivered into the patient's body, and it is desired to establish a technology that controls the generation of dissolved hydrogen based on the hydrogen delivered into the body.

The present invention has been proposed in view of the above facts, and its main purpose is to provide a technology for controlling the generation of dissolved hydrogen based on the hydrogen delivered to the patient's body during hemodialysis treatment using hydrogen-dissolved water.

(Technical solutions to solve problems)

A first invention of the present invention is a hydrogen-dissolved water generating device for generating hydrogen-dissolved water obtained by dissolving hydrogen in water. The hydrogen-dissolved water generating device includes: a hydrogen water generating unit that generates the hydrogen-dissolved water; A detection part for detecting hydrogen contained in the breath of a patient undergoing dialysis using dialysate prepared with the hydrogen-dissolved water; a control part for controlling the hydrogen gas according to the detection result of the detection part A water generating part is used to increase or decrease the dissolved hydrogen concentration of the hydrogen-dissolved water.

Preferably, in the hydrogen-dissolved water generating device according to the present invention, the control unit controls the hydrogen water generating unit based on the presence or absence of the hydrogen gas.

Preferably, in the hydrogen-dissolved water generating device according to the present invention, the control unit controls the hydrogen water generating unit based on the amount of hydrogen gas per unit volume of the exhaled breath.

Preferably, in the hydrogen-dissolved water generating device according to the present invention, the control unit controls the hydrogen water generating unit based on an average value of the amounts.

Preferably, in the hydrogen-dissolved water generating device according to the present invention, the control unit controls the hydrogen water generating unit based on the accumulated value of the amount.

Preferably, in the hydrogen-dissolved water generating device according to the present invention, the hydrogen-dissolved water generating device further includes a notification unit that notifies the amount of the hydrogen gas.

Preferably, in the hydrogen-dissolved water generating device according to the present invention, the hydrogen water generating unit includes an anode power supply and a cathode power supply for electrolyzing the water, and the control unit controls the supply of water to the hydrogen water. The current supplied by the anode power supply and the cathode power supply for the electrolysis is used to increase or decrease the dissolved hydrogen concentration of the hydrogen-dissolved water.

Preferably, in the hydrogen-dissolved water generating device according to the present invention, the hydrogen water generating part includes an anode donor and a cathode donor for electrolyzing the water. When the amount is less than a preset When the threshold value is reached, the control unit increases the current supplied to the anode power supply and the cathode power supply for the electrolysis.

The second invention of the present invention is a hydrogen-dissolved water generating method for generating hydrogen-dissolved water obtained by dissolving hydrogen in water. The hydrogen-dissolved water generating method includes a generating step of electrolyzing the water. generating the hydrogen-dissolved water; a detection step of using the dialysate prepared in the hydrogen-dissolved water to detect hydrogen contained in the breath of a patient undergoing dialysis; and a control step of controlling based on the detection result of the hydrogen gas The dissolved hydrogen concentration of the hydrogen-dissolved water.

(Invention effect)

The hydrogen-dissolved water generating device according to the first aspect of the present invention includes: a detection unit for detecting the hydrogen gas contained in the exhaled breath of the patient during dialysis; and a control unit for detecting The hydrogen water generating part is controlled based on the detection result of the detection part. Thereby, the generation of the hydrogen-dissolved water used for preparation of the dialysate can be appropriately controlled based on the hydrogen delivered into the patient's body.

The hydrogen-dissolved water production method of the second invention includes: the detection step of detecting the hydrogen gas contained in the exhaled breath of the patient undergoing dialysis; and the control step of detecting the hydrogen gas based on the detection result of the hydrogen gas. To control the dissolved hydrogen concentration of the hydrogen-dissolved water. Thereby, the dissolved hydrogen concentration of the hydrogen-dissolved water used for preparation of the dialysate can be appropriately controlled based on the hydrogen delivered into the patient's body.

Regarding the technical means of our inventors, several preferred embodiments are described in detail below along with the drawings, so that everyone can have a thorough understanding and recognition of the present invention.

Hereinafter, one embodiment of the present invention will be described based on the drawings.

FIG. 1 shows the schematic structure of a dialysis system 100 including the hydrogen-dissolved water generating device 1 of this embodiment. The hydrogen-dissolved water generating device 1 is a device for generating hydrogen-dissolved water in the dialysis system 100 using dialysate prepared with hydrogen-dissolved water.

The dialysis system 100 includes a reverse osmosis membrane treatment device 2 , a hydrogen-dissolved water generating device 1 , a dialysate preparation device 5 and a dialysis device 6 .

The reverse osmosis membrane treatment device 2 purifies raw water through reverse osmosis treatment and supplies it to the hydrogen-dissolved water generating device 1 . Although tap water is generally used as raw water, other water, such as well water, groundwater, etc., can be used.

The reverse osmosis membrane treatment device 2 includes a water softening treatment device 21 , an activated carbon treatment device 22 and a reverse osmosis membrane module 23 . The water softening treatment device 21 removes hardness components such as calcium ions and magnesium ions from raw water to soften the water. The activated carbon treatment device 22 includes activated carbon as a fine porous material, and adsorbs or removes chlorine and the like from the water supplied from the water softening treatment device 21 . The reverse osmosis membrane module 23 separates the water supplied from the activated carbon treatment device 22 into treated water purified by the reverse osmosis membrane and concentrated water containing impurities. The treated water purified by the reverse osmosis membrane module 23 is sent to the hydrogen-dissolved water generating device 1 . On the other hand, the concentrated water that cannot pass through the reverse osmosis membrane is discharged to the outside of the reverse osmosis membrane treatment device 2 .

The hydrogen-dissolved water generating device 1 adds hydrogen to the water purified by the reverse osmosis membrane treatment device 2 to generate hydrogen-dissolved water. The hydrogen-dissolved water generating device 1 includes a hydrogen water generating unit 3 for generating hydrogen-dissolved water (hydrogen-containing water) in which hydrogen gas is dissolved. In this embodiment, the electrolytic cell 4 is used as a part of the hydrogen water generating unit 3 . Details of the electrolytic tank 4 will be described later. The hydrogen-dissolved water generated by the hydrogen water generating unit 3 is sent to the dialysate preparation device 5 as dialysate preparation water.

The dialysate preparation device 5 uses the dialysate preparation water supplied from the hydrogen water generating unit 3 to prepare a dialysate by diluting, for example, a liquid dialysis reagent. The dialysate prepared by the dialysate preparation device 5 is sent to the dialysis device 6 .

The dialysis device 6 includes a dialysate supply device 61 and a dialyzer 62 . The dialysate supply device 61 sends the dialysate supplied from the dialysate preparation device 5 to the dialyzer 62 . The dialyzer 62 is, for example, an artificial kidney including a dialysis membrane 62a made of a porous membrane such as a hollow fiber, and causes the dialysate supplied from the dialysate preparation device 5 via the dialysis membrane 62a to act on the blood of the patient H undergoing dialysis treatment, thereby removing the blood from the blood. Remove metabolic waste and water.

The patient H and the dialyzer 62 are connected through blood circuits 63 and 64 . The blood circuit 63 sends the blood collected from the patient H to the dialyzer 62 . The blood circuit 63 is provided with a pump 65 for sending blood. The blood circuit 64 returns the blood from which metabolic waste and the like has been removed by the dialyzer 62 to the patient H.

The hydrogen-dissolved water generating device 1 includes, in addition to the hydrogen water generating unit 3 described above, a collecting unit 11 for collecting the exhaled breath of the patient H, a detecting unit 12 for detecting hydrogen gas contained in the exhaled breath of the patient H, and a user unit. In the control unit 13 that controls the hydrogen water generating unit 3.

The collection unit 11 is installed on the nose and corners of the mouth of the patient H, collects the exhaled breath of the patient H, and sends it to the detection unit 12 .

The detection unit 12 detects the amount of hydrogen gas contained in the exhaled breath of the patient H, and outputs a corresponding electrical signal to the control unit 13 . The detection unit 12 can use a known hydrogen gas detector or the like. In the form using the detection unit 12 capable of detecting hydrogen gas from exhaled breath such as the mouth of the patient H, the collection unit 11 is unnecessary.

The control unit 13 is composed of, for example, a CPU (Central Processing Unit) that performs various calculation processes, information processing, and the like, and a memory that stores programs responsible for the operation of the CPU and various information. The control unit 13 is responsible for controlling each unit of the hydrogen-dissolved water generating device 1 .

More specifically, the control unit 13 controls the hydrogen water generation unit 3 based on the electrical signal input from the detection unit 12 , that is, the detection result of the detection unit 12 . For example, when hydrogen gas is detected from the exhaled breath of the patient H, it can be confirmed that the hydrogen added by the hydrogen water generating unit 3 passes through the dialysate and blood and is definitely absorbed through the body of the patient H. Therefore, the hydrogen water generating unit 3 3's movement weakens or stops.

On the other hand, when hydrogen gas is not detected from the exhaled breath of the patient H, it can be confirmed that hydrogen has not spread throughout the body of the patient H. Therefore, for example, the operation of the hydrogen water generating unit 3, that is, the generation of hydrogen-dissolved water, is continued. In this case, the control unit 13 may control the operation of the hydrogen water generating unit 3 to increase the dissolved hydrogen concentration.

Therefore, according to the hydrogen-dissolved water generating device 1, the generation of hydrogen-dissolved water used for preparation of dialysate can be appropriately controlled based on the hydrogen sent into the body of the patient H.

In the present hydrogen-dissolved water generating device 1 , it is preferable that the detection unit 12 detects the amount of hydrogen gas per unit volume of exhaled breath, and the control unit 13 controls the hydrogen water generating unit 3 based on the amount of hydrogen gas detected by the detection unit 12 . . For example, the control unit 13 calculates the amount of hydrogen gas per unit volume of exhaled breath and compares it with a preset first threshold, thereby appropriately controlling the hydrogen water generating unit 3 . The first threshold can be defined, for example, by statistically processing information on the progression of symptoms of the patient H (hereinafter, the same applies to the second to sixth thresholds). With such a configuration, the hydrogen water generating unit 3 can be appropriately controlled based on the concentration of hydrogen gas in exhaled breath.

In addition, the amount of hydrogen gas may be volume, molecular weight, etc. in addition to mass. In addition, the control unit 13 may be configured to calculate the amount of hydrogen gas contained in the breath exhaled by the patient H per unit time.

In addition, in the hydrogen-dissolved water generating device 1 of the present invention, the control unit 13 may be configured to control the hydrogen water generating unit 3 based on the amount of hydrogen gas per unit volume of exhaled breath. For example, the control unit 13 controls the hydrogen water generating unit 3 by calculating the average amount of hydrogen gas per unit volume of exhaled breath and comparing it with a preset second threshold. The control unit 13 preferably calculates a moving average for every fixed period of time as the above-mentioned average value. With such a configuration, the hydrogen water generating unit 3 can be appropriately controlled without being affected by minute fluctuations in the concentration of hydrogen gas in exhaled breath.

In addition, in the present hydrogen-dissolved water generating device 1 , the control unit 13 may be configured to control the hydrogen water generating unit 3 based on the integrated value of the amount of hydrogen detected by the detecting unit 12 . For example, the control unit 13 controls the hydrogen water generation unit 3 by calculating the integrated value of the amount of hydrogen gas detected by the detection unit 12 and comparing it with a preset third threshold value. With such a configuration, the hydrogen water generating unit 3 can be appropriately controlled based on the hydrogen gas accumulated in the body of the patient H.

The present hydrogen-dissolved water generating device 1 preferably further includes a notification unit 14 that notifies the amount of hydrogen gas. For example, the notification unit 14 may use a speaker device or the like that outputs an audio signal in addition to an LED that outputs a light signal. Notifications can also use both light and sound signals. The operation of the notification unit 14 is controlled by the control unit 13, for example. By providing the notification unit 14 in the hydrogen-dissolved water generating device 1 , the doctor, nurse, or patient H can know that hydrogen has reached the body of the patient H through the notification unit 14 .

FIG. 2 shows the electrolytic cell 4 constituting the hydrogen water generating unit 3. The electrolytic cell 4 generates hydrogen molecules by electrolyzing water. By dissolving this hydrogen molecule in water, water to which the first hydrogen is added, that is, dissolved hydrogen water, is generated.

The electrolytic cell 4 is provided with an electrolysis chamber 40, and a first power supply 41 and a second power supply 42 are provided in the electrolysis chamber 40. The first power supply 41 and the second power supply 42 are provided in the electrolysis chamber 40 .

A diaphragm 43 is provided between the first power supply body 41 and the second power supply body 42 . The electrolysis chamber 40 is divided into a first electrode chamber 40 a provided with a first power supply 41 and a second electrode chamber 40 b provided with a second power supply 42 by a separator 43 .

The polarities of the first power supply body 41 and the second power supply body 42 and the voltages applied to the first power supply body 41 and the second power supply body 42 are controlled by the control unit 13 .

A current detector is provided on the current supply line between the power supplies 41 and 42 and the control unit 13 . The current detector detects the electrolysis current supplied to the first power supply 41 and the second power supply 42 and outputs an electrical signal corresponding to the value to the control unit 13 .

The control unit 13 controls the DC voltage applied to the first power supply 41 and the second power supply 42 based on, for example, an electrical signal output from a current detector. More specifically, the control unit 13 performs feedback control on the DC voltage applied to the first power supply 41 and the second power supply 42 so that the electrolysis current detected by the current detector reaches a preset desired value. For example, when the electrolysis current is too large, the control unit 13 decreases the voltage, and when the electrolysis current is too small, the control unit 13 increases the voltage. Thereby, the electrolysis current supplied to the first power supply body 41 and the second power supply body 42 is appropriately controlled.

Hydrogen and oxygen are generated by electrolyzing water in the electrolysis chamber 40 . For example, hydrogen gas is generated in the second electrode chamber 40 b on the cathode side, and hydrogen-dissolved water in which the hydrogen molecules are dissolved is generated, and the hydrogen-dissolved water is supplied to the reverse osmosis membrane module 23 of the reverse osmosis membrane treatment device 2 . In addition, the dissolved hydrogen water produced by such electrolysis is also called "electrolyzed hydrogen water", and dialysis treatment using electrolyzed hydrogen water is also called "electrolyzed water dialysis". On the other hand, oxygen is generated in the first electrode chamber 40a on the anode side.

The separator 43 may be a solid polymer membrane made of a fluorine-based resin having a sulfonic acid group, for example. The solid polymer membrane moves oxonium ions generated in the first electrode chamber 40a on the anode side to the second electrode chamber 40b on the cathode side through electrolysis, thereby serving as a hydrogen gas generation raw material. Therefore, no hydroxide ions are generated during electrolysis, and the pH of the hydrogen-dissolved water does not change.

In the present embodiment, the control unit 13 is preferably configured to control the amount of hydrogen gas supplied to the first power supply body 41 and the second power supply body 42 for electrolysis based on the amount of hydrogen gas per unit volume of exhalation detected by the detection unit 12 . current to make the dissolved hydrogen concentration of hydrogen-dissolved water larger or smaller.

More specifically, when the amount of hydrogen gas per unit volume of exhalation detected by the detection unit 12 is less than a preset threshold, the control unit 13 supplies the first power supply 41 and the second power supply 42 to The electrolysis current is controlled to be larger. On the other hand, when the amount of the hydrogen gas is greater than the preset threshold, the control unit 13 controls the current supplied to the first power supply 41 and the second power supply 42 for electrolysis to be small.

In addition, when the average or cumulative value of the amount of hydrogen gas detected by the detection unit 12 is less than a preset threshold, the control unit 13 may be configured to supply the first power supply body 41 and the second power supply body 42 to the first power supply body 41 and the second power supply body 42 . The electrolysis current is controlled to be larger. On the other hand, when the average or cumulative value of the amount of hydrogen gas is greater than a preset threshold, the control unit 13 may control the current for electrolysis supplied to the first power supply 41 and the second power supply 42 to be smaller. .

In addition, the control unit 13 may be configured to control the current for electrolysis supplied to the first power supply 41 and the second power supply 42 based on a combination of an average value and a cumulative value of the amount of hydrogen gas per unit volume of exhaled breath. Got bigger.

FIG. 3 shows the processing procedure of the hydrogen-dissolved water generating method 500 used in the hydrogen-dissolved water generating device 1 of the present invention. The hydrogen-dissolved water generation method 500 is executed during dialysis treatment using hydrogenated dialysate, and includes a generation process S1, detection processes S21 and S22, and control processes S3, S4, and S5.

In the generation step S1, the hydrogen water generation unit 3 generates dissolved hydrogen water. During the execution of dialysis treatment, the generation of hydrogen-dissolved water is in principle continued.

In the detection step S21, the collection unit 11 attached to the corner of the patient H's mouth collects the exhaled breath of the patient H during dialysis. In the detection step S22, the detection unit 12 detects hydrogen gas contained in the breath collected in the detection step S21. In the control steps S3 and S4, the control unit 13 controls the hydrogen water generating unit 3 based on the detection result (presence or absence of hydrogen gas) in the detection step S22. That is, when hydrogen gas is detected from exhaled breath (YES in S3), it can be judged that hydrogen gas has spread throughout the body of patient H, and therefore the operation of the hydrogen water generating unit 3 is weakened or stopped (S4). For example, in the control step S4, the control unit 13 weakens or cuts off the electric current used for electrolysis.

On the other hand, when hydrogen gas is not detected from the exhaled breath (NO in S3), the operation of the hydrogen water generating unit 3 is controlled (S5) to increase the dissolved hydrogen concentration, and the process returns to S21. For example, in the control step S5, the control unit 13 increases the current used for electrolysis.

According to the hydrogen-dissolved water generating method 500 , the generation of hydrogen-dissolved water used for preparation of dialysate can be appropriately controlled based on the hydrogen sent into the body of patient H.

FIG. 4 shows a hydrogen-dissolved water generating method 500A as a modification of the hydrogen-dissolved water generating method 500 of FIG. 3 . Regarding the parts of the hydrogen-dissolved water generating method 500A that are not explained below, the processing procedure of the above-described hydrogen-dissolved water generating method 500 can be adopted.

In the hydrogen-dissolved water generating method 500A, in addition to the control steps S3, S4, and S5 of the hydrogen-dissolved water generating method 500, the control steps S31 and S32 are also applied. In the control steps S3, S31, S32, S4, and S5, the control unit 13 calculates the amount of hydrogen gas per unit volume of exhaled breath based on the detection result in the detection step S22, thereby controlling the operation of the hydrogen water generating unit 3.

That is, when hydrogen gas is detected from exhaled breath in control process S3 (YES in S3), the process proceeds to control process S31. In the control step S31, the control unit 13 calculates the amount of hydrogen gas per unit volume of exhaled breath based on the detection result in the detection step S22. And when the amount of hydrogen gas is equal to or greater than the first threshold (YES in S32), the process proceeds to S4. It can be configured as follows: after executing S4, return to S21.

On the other hand, when the amount of hydrogen gas is less than the first threshold (NO in S32 ), the process proceeds to S5 and then returns to S21 . In the hydrogen-dissolved water generating method 500A, the control unit 13 controls the operation of the hydrogen-water generating unit 3 based on the concentration of hydrogen gas in exhaled breath. Therefore, the generation of hydrogen-dissolved water used for preparation of dialysate can be appropriately controlled.

FIG. 5 shows a hydrogen-dissolved water generating method 500B as a modification of the hydrogen-dissolved water generating method 500A of FIG. 3 . Regarding the portions of the hydrogen-dissolved water generating method 500B that are not described below, the processing procedures of the above-described hydrogen-dissolved water generating method 500A and the like can be used.

In the hydrogen-dissolved water generating method 500B, the control steps S33 and S34 are applied in place of the control steps S31 and S32 of the hydrogen-dissolved water generating method 500A. In the control steps S3, S33, S34, S4, and S5, the control unit 13 calculates the average amount of hydrogen gas per unit volume of the exhaled breath based on the detection result in the detection step S22, and controls the operation of the hydrogen water generating unit 3 .

That is, when hydrogen gas is detected from exhaled breath in control process S3 (YES in S3), the process proceeds to control process S33. In the control step S33, the control unit 13 calculates an average value of the amount of hydrogen gas per unit volume of exhaled breath based on the detection result in the detection step S22. Furthermore, when the average value of the amount of hydrogen gas is equal to or greater than the second threshold (YES in S34 ), the process moves to S4 . On the other hand, when the average value of the amount of hydrogen gas is less than the second threshold (NO in S34 ), the process proceeds to S5 and then returns to S21 . In the hydrogen-dissolved water generating method 500B, the operation of the hydrogen water generating unit 3 is controlled based on the average concentration of hydrogen gas in the exhaled breath. Therefore, it is not affected by slight fluctuations in the concentration of hydrogen gas in the exhaled breath and can be appropriately Controlling the generation of hydrogen-dissolved water used in the preparation of dialysate.

FIG. 6 shows a hydrogen-dissolved water generating method 500C as another modification of the hydrogen-dissolved water generating method 500A of FIG. 3 . Regarding the portions of the hydrogen-dissolved water generating method 500C that are not explained below, processes such as the above-described hydrogen-dissolved water generating method 500A can be used.

In the hydrogen-dissolved water generating method 500C, the control steps S35 and S36 are applied in place of the control steps S31 and S32 of the hydrogen-dissolved water generating method 500A. In the control steps S3, S35, S36, S4, and S5, the control unit 13 calculates the cumulative value of the amount of hydrogen gas per unit volume of the exhaled breath based on the detection result in the detection step S22, thereby controlling the operation of the hydrogen water generating unit 3 .

That is, when hydrogen gas is detected from exhaled breath in control process S3 (YES in S3), the process proceeds to control process S35. In the control step S35, the control unit 13 calculates the integrated value of the amount of hydrogen gas based on the detection result in the detection step S22. Furthermore, when the accumulated value of the amount of hydrogen gas is equal to or greater than the third threshold (YES in S35 ), the process proceeds to S4 . On the other hand, when the accumulated value of the amount of hydrogen gas is less than the third threshold (NO in S36 ), the process proceeds to S5 and then returns to S21 . In the dissolved hydrogen water generating method 500C, the operation of the hydrogen water generating unit 3 is controlled based on the accumulated value of the amount of hydrogen gas. Therefore, the dissolved hydrogen used for preparation of the dialysate can be appropriately controlled based on the hydrogen gas accumulated in the body of the patient H. The production of water.

Although the hydrogen-dissolved water generating device 1 of the present invention has been described in detail above, the present invention is not limited to the specific embodiment described above and can be implemented in various forms. That is, the hydrogen-dissolved water generating device 1 is a device for generating hydrogen-dissolved water obtained by dissolving hydrogen in water. It is provided with at least a hydrogen water generating part 3 for generating dissolved hydrogen water, and is used for using the hydrogen-dissolved water prepared with hydrogen-dissolved water. A detection unit 12 for detecting hydrogen gas contained in the exhaled breath of the patient H undergoing dialysis using dialysate, and a control unit 13 for controlling the hydrogen water generation unit 3 based on the detection result of the detection unit 12 are sufficient.

Therefore, for example, the control unit 13 may be configured to determine that dialysis is completed when the amount of hydrogen gas per unit volume of exhalation or the above-mentioned average amount of hydrogen gas exceeds a preset fourth threshold or fifth threshold. . In addition, the control unit 13 may be configured to determine that dialysis is completed when the integrated value of the amount of hydrogen gas exceeds a preset sixth threshold.

In addition, the hydrogen water generating unit 3 is not limited to the electrolytic cell 4 that generates dissolved hydrogen water by electrolyzing water. For example, it may be a device that generates dissolved hydrogen water by dissolving hydrogen molecules generated by a chemical reaction between water and magnesium in water. , or it may be a device that dissolves hydrogen gas (hydrogen molecules) supplied from a hydrogen storage tank in water to generate hydrogen-dissolved water.

In addition, the present hydrogen-dissolved water generating method 500 and the like are methods for generating hydrogen-dissolved water obtained by dissolving hydrogen in water, and include at least a generating step S1 of generating dissolved hydrogen water, and using a dialysate prepared with hydrogen-dissolved water. It suffices to perform the detection step S22 of detecting the hydrogen gas contained in the exhaled breath of the patient H undergoing dialysis, and the control steps S3 to S5 of controlling the dissolved hydrogen concentration of the hydrogen-dissolved water based on the hydrogen gas detection result.

In summary, the technical means disclosed in the present invention can indeed effectively solve the problems of conventional knowledge and achieve the expected purposes and effects. They have not been published in publications or publicly used before the application and are of long-term progress. They are truly worthy of the title. The invention described in the Patent Law is correct, and I submit the application in accordance with the law. I sincerely pray that Jun will review it carefully and grant an invention patent. I am deeply grateful.

However, the above are only several preferred embodiments of the present invention, and should not be used to limit the scope of the present invention. That is, all equivalent changes and modifications made based on the patent scope of the present invention and the content of the invention specification are It should still fall within the scope of the patent of this invention.

[Invention] 1: Dialysis determination device 100:Dialysis system 11:Collection Department 12:Testing Department 13:Control Department 14:Notification Department 2: Reverse osmosis membrane treatment device 21:Water softening treatment device 22: Activated carbon treatment device 23:Reverse osmosis membrane module 3: Hydrogen water generation part 4:Electrolyzer 40:Electrolysis room 40a:First pole chamber 40b:Second pole chamber 41:First power supply 42:Second power supply 43: Diaphragm 5: Dialysate preparation device 500: Method for generating dissolved hydrogen water 500A: Method for generating dissolved hydrogen water 500B: Method for generating dissolved hydrogen water 500C: Method for generating dissolved hydrogen water 6: Dialysis device 61: Dialysate supply device 62:Dialyzer 62a: Dialysis membrane 63, 64: blood circuit 65:Pump S1: Generation process S21, S22: Inspection process S3, S4, S5: control process S31, S32, S33, S34, S35, S36: control process H:Patient

[Fig. 1] is a diagram showing the schematic structure of a dialysis system including the hydrogen-dissolved water generating device of the present invention; [Fig. 2] is a diagram showing an electrolytic cell as an example of the hydrogen-dissolved water generating unit in Fig. 1; [Fig. 3] is a flow chart showing the processing procedure of the hydrogen-dissolved water generating method used in the hydrogen-dissolved water generating device of Fig. 1; [Fig. 4] A flowchart showing a processing procedure of a modified example of the hydrogen-dissolved water generation method of Fig. 3; [Fig. 5] is a flowchart showing a processing procedure of another modification of the hydrogen-dissolved water generation method of Fig. 4; [FIG. 6] is a flowchart showing the processing procedure of still another modified example of the hydrogen-dissolved water generation method of FIG. 4. [FIG.

1: Dialysis determination device

100:Dialysis system

11:Collection Department

12:Testing Department

13:Control Department

14:Notification Department

2: Reverse osmosis membrane treatment device

21:Water softening treatment device

22: Activated carbon treatment device

23:Reverse osmosis membrane module

3: Hydrogen water generation part

5: Dialysate preparation device

6: Dialysis device

61: Dialysate supply device

62:Dialyzer

62a: Dialysis membrane

63, 64: blood circuit

65:Pump

H:Patient

Claims (7)

A hydrogen-dissolved water generating device for generating hydrogen-dissolved water obtained by dissolving hydrogen in water. The hydrogen-dissolved water generating device is provided with: a hydrogen water generating part for generating the hydrogen-dissolved water; and a detection part for use using the dialysate prepared by the hydrogen-dissolved water to detect hydrogen contained in the breath of the patient undergoing dialysis; and a control unit for controlling the hydrogen water generating unit based on the detection results of the detection unit, so The control unit controls the hydrogen water generating unit based on an accumulated value of the amount of hydrogen gas per unit volume of the exhaled breath. The hydrogen-dissolved water generating device according to claim 1, wherein the control unit controls the hydrogen water generating unit according to the presence or absence of the hydrogen gas. The hydrogen-dissolved water generating device according to claim 1, wherein the control unit controls the hydrogen water generating unit based on an average value of the amounts. The hydrogen-dissolved water generating device according to any one of claims 1 to 3, wherein the hydrogen-dissolved water generating device further includes a notification unit that notifies the amount of the hydrogen gas. The hydrogen-dissolved water generating device according to any one of claims 1 to 3, wherein the hydrogen water generating part includes an anode power supply and a cathode power supply for electrolyzing the water, and the control part The current supplied to the anode power supply and the cathode power supply for the electrolysis is controlled to increase or decrease the dissolved hydrogen concentration of the hydrogen-dissolved water. The hydrogen-dissolved water generating device as described in claim 1 or 3, wherein, The hydrogen water generating part includes an anode power supply and a cathode power supply for electrolyzing the water. When the amount is less than a preset threshold, the control part increases the amount of power supplied to the anode power supply and the cathode power supply. The cathode supplies the electrical current used for the electrolysis. A method for generating dissolved hydrogen water, which is used to generate dissolved hydrogen water obtained by dissolving hydrogen in water. The method for generating dissolved hydrogen water includes: a generating step to generate the dissolved hydrogen water; and a detecting step to use the dissolved hydrogen water. The dialysate prepared by hydrogen water is used to detect the hydrogen contained in the exhaled breath of the patient undergoing dialysis; and the control process is to control the dissolved hydrogen concentration of the hydrogen-dissolved water according to the detection result of the hydrogen, in the In the control step, the generation step is controlled based on an accumulated value of the amount of hydrogen gas per unit volume of the exhaled breath.