TW202108190A - Hydrogen-dissolved water generating device and hydrogen-dissolved water generating method - Google Patents

Hydrogen-dissolved water generating device and hydrogen-dissolved water generating method Download PDF

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TW202108190A
TW202108190A TW109108996A TW109108996A TW202108190A TW 202108190 A TW202108190 A TW 202108190A TW 109108996 A TW109108996 A TW 109108996A TW 109108996 A TW109108996 A TW 109108996A TW 202108190 A TW202108190 A TW 202108190A
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TWI821544B (en
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仲西直樹
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日本多寧股份有限公司
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes

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Abstract

The present disclosure provides a technology capable of controlling generation of hydrogen-dissolved water based on hydrogen delivered to a patient's body in hemodialysis treatment using hydrogen-dissolved water. The hydrogen-dissolved water generating device (1) is a device for generating hydrogen-dissolved water obtained by dissolving hydrogen into water. The hydrogen-dissolved water generating device (1) includes: a hydrogen water generating unit (3) that is configured to generate hydrogen-dissolved water; a detection unit (12) that is configured to detect hydrogen contained in the breath of a patient (H) undergoing dialysis using a dialysate prepared with hydrogen-dissolved water; and a control unit (13) that is configured to control the hydrogen water generating unit (3) according to a detection result of the detection unit (12).

Description

溶氫水生成裝置以及溶氫水生成方法Hydrogen-dissolved water generating device and hydrogen-dissolved water generating method

本發明涉及用於生成在透析液的製備中使用的溶氫水的溶氫水生成裝置以及溶氫水生成方法。The present invention relates to a hydrogen-dissolved water generating device and a hydrogen-dissolved water generating method for generating hydrogen-dissolved water used in the preparation of dialysate.

在血液透析治療中,採用溶入有氫的溶氫水所製備的透析液有助於降低患者的氧化應激,因此近年備受關注(例如,參照專利文獻1)。In hemodialysis treatment, a dialysate prepared using hydrogen-dissolved water in which hydrogen is dissolved helps to reduce the oxidative stress of patients, and therefore has attracted attention in recent years (for example, refer to Patent Document 1).

在先技術文獻Prior Art Literature

專利文獻Patent literature

專利文獻1:JP特開5840248號公報Patent Document 1: JP Patent Laid-Open No. 5840248

有鑑於此,吾等發明人乃潛心進一步研究,並著手進行研發及改良,期以一較佳發明以解決上述問題,且在經過不斷試驗及修改後而有本發明之問世。In view of this, our inventors devoted themselves to further research, and proceeded to develop and improve, hoping to develop a better invention to solve the above problems, and after continuous experimentation and modification, the present invention came out.

(發明要解決的課題)(The problem to be solved by the invention)

在利用上述專利文獻1中所公開的裝置的透析治療中,氫以何種程度被送至患者的體內是不清楚的,期望建立一種根據送至體內的氫來控制溶氫的生成的技術。In the dialysis treatment using the device disclosed in Patent Document 1, it is not clear to what extent hydrogen is delivered to the patient's body, and it is desired to establish a technology for controlling the generation of dissolved hydrogen based on the hydrogen delivered to the body.

本發明鑑於以上事實而提出,主要目的在於,提供一種技術,用於在採用溶氫水的血液透析治療中,根據送至患者的體內的氫來控制溶氫的生成。The present invention is proposed in view of the above facts, and its main purpose is to provide a technique for controlling the generation of dissolved hydrogen based on the hydrogen delivered to the patient's body in hemodialysis treatment using hydrogen-dissolved water.

(用於解決課題的技術方案)(Technical solution to solve the problem)

本發明的第一發明是用於生成在水中溶入有氫而得到的溶氫水的溶氫水生成裝置,所述溶氫水生成裝置具備:氫水生成部,生成所述溶氫水;檢測部,用於使用以所述溶氫水所製備的透析液來檢測接受透析的患者的呼氣中所含的氫氣;控制部,用於根據所述檢測部的檢測結果來控制所述氫水生成部,以增大或減小所述溶氫水的溶氫濃度。The first invention of the present invention is a hydrogen-dissolved water generating device for generating hydrogen-dissolved water obtained by dissolving hydrogen in water, the hydrogen-dissolved water generating device including: a hydrogen water generating unit that generates the hydrogen-dissolved water; The detection unit is used to detect the hydrogen contained in the breath of the patient undergoing dialysis using the dialysate prepared with the hydrogen-dissolved water; the control unit is used to control the hydrogen according to the detection result of the detection unit The water generating part is used to increase or decrease the dissolved hydrogen concentration of the hydrogen dissolved water.

優選地,在本發明所涉及的所述溶氫水生成裝置中,所述控制部根據所述氫氣的有無來控制所述氫水生成部。Preferably, in the hydrogen-dissolved water generating device according to the present invention, the control unit controls the hydrogen water generating unit according to the presence or absence of the hydrogen gas.

優選地,在本發明所涉及的所述溶氫水生成裝置中,所述控制部根據所述呼氣的每單位體積的所述氫氣的量來控制所述氫水生成部。Preferably, in the hydrogen-dissolved water generating device according to the present invention, the control unit controls the hydrogen water generating unit based on the amount of the hydrogen gas per unit volume of the exhalation.

優選地,在本發明所涉及的所述溶氫水生成裝置中,所述控制部根據所述量的平均值來控制所述氫水生成部。Preferably, in the hydrogen-dissolved water generating device according to the present invention, the control unit controls the hydrogen water generating unit based on an average value of the amount.

優選地,在本發明所涉及的所述溶氫水生成裝置中,所述控制部根據所述量的累積值來控制所述氫水生成部。Preferably, in the hydrogen-dissolved water generating device according to the present invention, the control unit controls the hydrogen water generating unit based on a cumulative value of the amount.

優選地,在本發明所涉及的所述溶氫水生成裝置中,所述溶氫水生成裝置還具備通知部,所述通知部通知所述氫氣的所述量。Preferably, in the hydrogen-dissolved water generating device according to the present invention, the hydrogen-dissolved water generating device further includes a notification unit that notifies the amount of the hydrogen gas.

優選地,在本發明所涉及的所述溶氫水生成裝置中,所述氫水生成部包含用於對所述水進行電解的陽極供電體和陰極供電體,所述控制部控制向所述陽極供電體以及所述陰極供電體供給的用於所述電解的電流,以增大或減小所述溶氫水的溶氫濃度。Preferably, in the hydrogen-dissolved water generating device according to the present invention, the hydrogen-water generating unit includes an anode power supply body and a cathode power supply body for electrolyzing the water, and the control unit controls The current supplied by the anode power supply body and the cathode power supply body for the electrolysis is used to increase or decrease the dissolved hydrogen concentration of the hydrogen dissolved water.

優選地,在本發明所涉及的所述溶氫水生成裝置中,所述氫水生成部包含用於對所述水進行電解的陽極供電體和陰極供電體,在所述量小於預先設定的閾值時,所述控制部增大向所述陽極供電體以及所述陰極供電體供給的用於所述電解的電流。Preferably, in the hydrogen-dissolved water generator according to the present invention, the hydrogen-water generator includes an anode power supply body and a cathode power supply body for electrolyzing the water, and the amount is less than a preset amount. At the threshold value, the control unit increases the current for the electrolysis supplied to the anode power supply body and the cathode power supply body.

本發明的第二發明是一種溶氫水生成方法,用於生成在水中溶入有氫而得到的溶氫水,所述溶氫水生成方法包含:生成工序,通過對所述水進行電解來生成所述溶氫水;檢測工序,使用以所述溶氫水中所製備的透析液來檢測接受透析的患者的呼氣中所含的氫氣;以及控制工序,根據所述氫氣的檢測結果來控制所述溶氫水的溶氫濃度。The second invention of the present invention is a hydrogen-dissolved water generating method for generating hydrogen-dissolved water obtained by dissolving hydrogen in water. The hydrogen-dissolved water generating method includes a generating step of electrolyzing the water. Generating the hydrogen-dissolved water; a detection step of using the dialysate prepared from the hydrogen-dissolved water to detect hydrogen contained in the breath of a patient undergoing dialysis; and a control step of controlling based on the detection result of the hydrogen The dissolved hydrogen concentration of the hydrogen-dissolved water.

(發明效果)(Inventive effect)

本第一發明的所述溶氫水生成裝置具備:所述檢測部,檢測所述透析中的所述患者的所述呼氣中所含的所述氫氣;以及所述控制部,用於根據所述檢測部的檢測結果來控制所述氫水生成部。由此,能根據送至所述患者的體內的所述氫來適當地控制用於所述透析液的製備的所述溶氫水的生成。The hydrogen-dissolved water generating device according to the first aspect of the present invention includes: the detection unit that detects the hydrogen contained in the exhalation of the patient during the dialysis; and the control unit for detecting the The detection result of the detection unit controls the hydrogen water generating unit. Thus, the production of the hydrogen-dissolved water used for the preparation of the dialysate can be appropriately controlled based on the hydrogen delivered to the patient's body.

本第二發明的所述溶氫水生成方法包含:所述檢測工序,檢測所述透析中的患者的呼氣中所含的所述氫氣;以及控制工序,根據所述氫氣的所述檢測結果來控制所述溶氫水的溶氫濃度。由此,能根據送至所述患者的體內的所述氫來適當地控制用於所述透析液的製備的所述溶氫水的溶氫濃度。The method for producing hydrogen-dissolved water according to the second aspect of the present invention includes: the detecting step, detecting the hydrogen contained in the breath of the patient during dialysis; and a controlling step, based on the detection result of the hydrogen To control the dissolved hydrogen concentration of the hydrogen-dissolved water. Thereby, the dissolved hydrogen concentration of the hydrogen-dissolved water used for the preparation of the dialysate can be appropriately controlled based on the hydrogen delivered to the patient's body.

關於吾等發明人之技術手段,茲舉數種較佳實施例配合圖式於下文進行詳細說明,俾供  鈞上深入瞭解並認同本發明。Regarding the technical means of our inventors, several preferred embodiments are described in detail below in conjunction with the drawings, in order to provide a thorough understanding and approval of the present invention.

以下,基於附圖來說明本發明的一實施方式。Hereinafter, an embodiment of the present invention will be described based on the drawings.

圖1示出了包含本實施方式的溶氫水生成裝置1的透析系統100的概略構成。溶氫水生成裝置1是在使用以溶氫水所製備的透析液的透析系統100中用於生成溶氫水的裝置。Fig. 1 shows a schematic configuration of a dialysis system 100 including a hydrogen-dissolved water generator 1 of the present embodiment. The hydrogen-dissolved water generator 1 is a device for generating hydrogen-dissolved water in a dialysis system 100 that uses a dialysate prepared with hydrogen-dissolved water.

透析系統100包含反滲透膜處理裝置2、溶氫水生成裝置1、透析液製備裝置5以及透析裝置6。The dialysis system 100 includes a reverse osmosis membrane processing device 2, a hydrogen-dissolved water generating device 1, a dialysate preparation device 5, and a dialysis device 6.

反滲透膜處理裝置2通過反滲透處理對原水進行淨化,並供給至溶氫水生成裝置1。雖然原水一般採用自來水,但除此以外,能使用其他水,例如,井水、地下水等。The reverse osmosis membrane treatment device 2 purifies the raw water through reverse osmosis treatment, and supplies it to the hydrogen-dissolved water generator 1. Although tap water is generally used as raw water, other water, such as well water, ground water, etc., can be used in addition to this.

反滲透膜處理裝置2包含軟水化處理裝置21、活性碳處理裝置22以及反滲透膜模塊23。軟水化處理裝置21從原水中去除鈣離子以及鎂離子等的硬度成分而軟水化。活性碳處理裝置22具有作為微細的多孔質物質的活性碳,從軟水化處理裝置21供給的水中吸附或去除氯等。反滲透膜模塊23將從活性碳處理裝置22供給的水分離為由反滲透膜進行淨化後的處理水與包含雜質的濃縮水。由反滲透膜模塊23淨化後的處理水送至溶氫水生成裝置1。另一方面,未能透過反滲透膜的濃縮水排出至反滲透膜處理裝置2的外部。The reverse osmosis membrane treatment device 2 includes a water softening treatment device 21, an activated carbon treatment device 22 and a reverse osmosis membrane module 23. The water softening treatment device 21 removes hardness components such as calcium ions and magnesium ions from the raw water to soften the water. The activated carbon treatment device 22 has activated carbon as a fine porous substance, and adsorbs or removes chlorine and the like from the water supplied from the water softening treatment device 21. The reverse osmosis membrane module 23 separates the water supplied from the activated carbon treatment device 22 into treated water purified by the reverse osmosis membrane and concentrated water containing impurities. The treated water purified by the reverse osmosis membrane module 23 is sent to the hydrogen-dissolved water generator 1. On the other hand, the concentrated water that failed to pass through the reverse osmosis membrane is discharged to the outside of the reverse osmosis membrane treatment device 2.

溶氫水生成裝置1在由反滲透膜處理裝置2淨化處理後的水中加氫而生成溶氫水。溶氫水生成裝置1包含用於生成溶入有氫氣的溶氫水(含氫水)的氫水生成部3。在本實施方式中,應用了電解槽4作為氫水生成部3的一部分。關於電解槽4的細節將後述。由氫水生成部3生成的溶氫水作為透析液製備用水而被送至透析液製備裝置5。The hydrogen-dissolved water generator 1 hydrogenates the water purified by the reverse osmosis membrane treatment unit 2 to generate hydrogen-dissolved water. The hydrogen-dissolved water generator 1 includes a hydrogen-dissolved water generator 3 for generating hydrogen-dissolved water (hydrogen-containing water) in which hydrogen gas is dissolved. In this embodiment, the electrolytic cell 4 is applied as a part of the hydrogen water generator 3. The details of the electrolytic cell 4 will be described later. The hydrogen-dissolved water produced by the hydrogen water producing unit 3 is sent to the dialysate preparation device 5 as dialysate preparation water.

透析液製備裝置5使用從氫水生成部3供給的透析液製備用水,例如對液狀的透析原劑進行稀釋來製備透析液。由透析液製備裝置5製備的透析液被送至透析裝置6。The dialysate preparation device 5 uses the dialysate preparation water supplied from the hydrogen water generating unit 3 to, for example, dilute a liquid dialysis agent to prepare a dialysate. The dialysate prepared by the dialysate preparation device 5 is sent to the dialysis device 6.

透析裝置6包含透析液供給裝置61和透析器62。透析液供給裝置61將從透析液製備裝置5供給的透析液送出至透析器62。透析器62例如是包含由中空纖維等多孔質膜構成的透析膜62a的人工腎臟,使經由透析膜62a從透析液製備裝置5供給的透析液作用於接受透析治療的患者H的血液,從血液中去除代謝廢物以及水分。The dialysis device 6 includes a dialysate supply device 61 and a dialyzer 62. The dialysate supply device 61 sends out the dialysate supplied from the dialysate preparation device 5 to the dialyzer 62. The dialyzer 62 is, for example, an artificial kidney including a dialysis membrane 62a composed of a porous membrane such as hollow fibers, and causes the dialysate supplied from the dialysate preparation apparatus 5 via the dialysis membrane 62a to act on the blood of the patient H undergoing dialysis treatment. Remove metabolic waste and water.

患者H與透析器62通過血液回路63、64進行連接。血液回路63將從患者H採集的血液送至透析器62。在血液回路63設置有用於送出血液的泵65。血液回路64使由透析器62去除代謝廢物等後的血液返回患者H。The patient H and the dialyzer 62 are connected through blood circuits 63 and 64. The blood circuit 63 sends the blood collected from the patient H to the dialyzer 62. The blood circuit 63 is provided with a pump 65 for sending blood. The blood circuit 64 returns the blood from which metabolic wastes and the like have been removed by the dialyzer 62 to the patient H.

溶氫水生成裝置1除具備上述氫水生成部3以外,還具備用於採集患者H的呼氣的採集部11、用於檢測患者H的呼氣中所含的氫氣的檢測部12以及用於控制氫水生成部3的控制部13。The hydrogen-dissolved water generating device 1 includes, in addition to the above-mentioned hydrogen water generating unit 3, a collection unit 11 for collecting the exhalation of the patient H, a detection unit 12 for detecting the hydrogen contained in the exhalation of the patient H, and a In the control unit 13 that controls the hydrogen water generating unit 3.

採集部11安裝於患者H的鼻子以及嘴角,採集患者H的呼氣並送到檢測部12。The collection unit 11 is attached to the nose and the corner of the mouth of the patient H, collects the breath of the patient H, and sends it to the detection unit 12.

檢測部12檢測患者H的呼氣中所含的的氫氣的量,且將對應的電信號輸出至控制部13。檢測部12能採用已知的氫氣探測器等。在採用能從患者H的口內等的呼氣中檢測氫氣的檢測部12的形態中,採集部11是不需要的。The detection unit 12 detects the amount of hydrogen contained in the breath of the patient H, and outputs a corresponding electric signal to the control unit 13. The detection unit 12 can employ a known hydrogen gas detector or the like. In the form of adopting the detection unit 12 capable of detecting hydrogen gas from the breath of the patient H, etc., the collection unit 11 is unnecessary.

控制部13例如由具有執行各種運算處理、信息處理等的CPU(Central Processing Unit)以及對負責CPU的動作的程序以及各種信息進行存儲的存儲器等構成。控制部13負責溶氫水生成裝置1的各部的控制。The control unit 13 is composed of, for example, a CPU (Central Processing Unit) that executes various arithmetic processing, information processing, and the like, and a memory that stores programs and various information in charge of the operation of the CPU. The control unit 13 is responsible for the control of each unit of the hydrogen-dissolved water generator 1.

更具體而言,控制部13根據從檢測部12輸入的電信號,即,檢測部12的檢測結果,來控制氫水生成部3。例如,在從患者H的呼氣中檢測到氫氣的情況下,能確認由氫水生成部3附加的氫通過透析液以及血液確切地遍及患者H的體內而被吸收,因此使氫水生成部3的動作減弱或停止。More specifically, the control unit 13 controls the hydrogen water generating unit 3 based on the electrical signal input from the detection unit 12, that is, the detection result of the detection unit 12. For example, when hydrogen gas is detected in the breath of the patient H, it can be confirmed that the hydrogen added by the hydrogen water generator 3 is absorbed by the dialysate and blood throughout the body of the patient H. Therefore, the hydrogen water generator 3's actions are weakened or stopped.

另一方面,在未從患者H的呼氣中檢測到氫氣的情況下,能確認氫還未遍及患者H的體內,因此例如繼續氫水生成部3的動作,即,溶氫水的生成。在此情況下,控制部13也可以控制氫水生成部3的動作以增大溶氫濃度。On the other hand, if hydrogen is not detected in the breath of the patient H, it can be confirmed that the hydrogen has not spread throughout the body of the patient H. Therefore, for example, the operation of the hydrogen water generating unit 3, that is, the generation of hydrogen-dissolved water is continued. In this case, the control unit 13 may also control the operation of the hydrogen water generating unit 3 to increase the dissolved hydrogen concentration.

因此,根據溶氫水生成裝置1,能根據送至患者H的體內的氫來適當地控制用於透析液的製備的溶氫水的生成。Therefore, according to the hydrogen-dissolved water generator 1, it is possible to appropriately control the production of hydrogen-dissolved water used for the preparation of the dialysate in accordance with the hydrogen delivered to the body of the patient H.

在本溶氫水生成裝置1中,優選構成為:檢測部12檢測呼氣的每單位體積的氫氣的量,控制部13根據由檢測部12檢測出的氫氣的量來控制氫水生成部3。例如,控制部13通過計算呼氣的每單位體積的氫氣的量,並與預先設定的第一閾值進行比較,從而適當地控制氫水生成部3。第一閾值例如能通過以統計的方式處理與患者H的症狀的推移相關的信息來規定(以下,關於第二閾值至第六閾值也相同)。在這樣的構成中,能根據呼氣中的氫氣的濃度來適當地控制氫水生成部3。In the present hydrogen-dissolved water generating device 1, it is preferable that the detecting unit 12 detects the amount of hydrogen per unit volume of exhalation, and the control unit 13 controls the hydrogen water generating unit 3 based on the amount of hydrogen detected by the detecting unit 12 . For example, the control unit 13 calculates the amount of hydrogen gas per unit volume of exhalation and compares it with a first threshold set in advance, thereby appropriately controlling the hydrogen water generator 3. The first threshold value can be defined by, for example, statistically processing information related to the transition of the symptoms of the patient H (hereinafter, the same applies to the second threshold value to the sixth threshold value). In such a configuration, the hydrogen water generator 3 can be appropriately controlled in accordance with the concentration of hydrogen gas in the breath.

此外,作為上述氫氣的量,除了質量以外,也可以是體積、分子量等。另外,控制部13也可以構成為計算患者H單位時間呼出的呼氣中所含的氫氣的量。In addition, as the amount of the above-mentioned hydrogen, in addition to mass, volume, molecular weight, etc. may also be used. In addition, the control unit 13 may be configured to calculate the amount of hydrogen contained in the breath exhaled by the patient H per unit time.

另外,在本溶氫水生成裝置1中,控制部13也可以構成為根據呼氣的每單位體積的氫氣的量來控制氫水生成部3。例如,控制部13通過計算呼氣的每單位體積的氫氣的量的平均值並與預先設定的第二閾值進行比較,從而控制氫水生成部3。控制部13優選計算每段固定時間的移動平均值來作為上述平均值的形態。在這樣的構成中,不受呼氣中的氫氣的濃度的微小的變動影響,能適當地控制氫水生成部3。In addition, in the present hydrogen-dissolved water generator 1, the control unit 13 may be configured to control the hydrogen-water generator 3 based on the amount of hydrogen per unit volume of exhalation. For example, the control unit 13 controls the hydrogen water generator 3 by calculating the average value of the amount of hydrogen per unit volume of the exhalation and comparing it with a preset second threshold value. The control unit 13 preferably calculates a moving average value for each fixed period of time as the form of the above average value. In such a configuration, the hydrogen water generator 3 can be appropriately controlled without being affected by slight fluctuations in the concentration of hydrogen in the breath.

另外,在本溶氫水生成裝置1中,控制部13也可以構成為根據由檢測部12檢測出的氫氣的量的累積值來控制氫水生成部3。例如,控制部13通過計算由檢測部12檢測到的氫氣的量的累積值,並與預先設定的第三閾值進行比較,從而控制氫水生成部3。在這樣的構成中,能根據蓄積於患者H的體內的氫氣來適當地控制氫水生成部3。In addition, in the present hydrogen-dissolved water generating device 1, the control unit 13 may be configured to control the hydrogen water generating unit 3 based on the cumulative value of the amount of hydrogen detected by the detecting unit 12. For example, the control unit 13 calculates the cumulative value of the amount of hydrogen gas detected by the detection unit 12 and compares it with a preset third threshold value, thereby controlling the hydrogen water generating unit 3. In such a configuration, the hydrogen water generator 3 can be appropriately controlled based on the hydrogen gas accumulated in the body of the patient H.

在本溶氫水生成裝置1中,優選還具備通知部14,通知部14通知氫氣的量。通知部14例如除了採用輸出光信號的LED等以外,還採用輸出聲音信號的揚聲器裝置等。通知也可以兼用光信號和聲音信號。通知部14的動作例如由控制部13控制。通過在溶氫水生成裝置1中設置通知部14,醫師、護士或患者H能通過通知部14得知氫已到達患者H的體內。In the present hydrogen-dissolved water generating device 1, it is preferable to further include a notification unit 14 that notifies the amount of hydrogen gas. The notification unit 14 uses, for example, a speaker device that outputs a sound signal and the like, in addition to an LED that outputs a light signal and the like. The notification can also use both light and sound signals. The operation of the notification unit 14 is controlled by, for example, the control unit 13. By providing the notification unit 14 in the hydrogen-dissolved water generating device 1, the doctor, nurse or patient H can know through the notification unit 14 that hydrogen has reached the body of the patient H.

圖2示出了構成氫水生成部3的電解槽4。電解槽4通過對水進行電解來產生氫分子。通過使該氫分子溶入於水,來生成附加有第一氫的水即溶氫水。FIG. 2 shows the electrolytic cell 4 constituting the hydrogen water generating unit 3. The electrolytic cell 4 electrolyzes water to generate hydrogen molecules. By dissolving the hydrogen molecules in water, hydrogen-dissolved water that is water to which the first hydrogen is added is generated.

電解槽4具備電解室40,在電解室40內具有第一供電體41和第二供電體42。第一供電體41以及第二供電體42設置於電解室40。The electrolysis tank 4 includes an electrolysis chamber 40, and a first power supply body 41 and a second power supply body 42 are provided in the electrolysis chamber 40. The first power supply body 41 and the second power supply body 42 are installed in the electrolysis chamber 40.

在第一供電體41與第二供電體42之間設置有隔膜43。電解室40通過隔膜43而被劃分為配有第一供電體41的第一極室40a和配有第二供電體42的第二極室40b。A diaphragm 43 is provided between the first power supply body 41 and the second power supply body 42. The electrolysis chamber 40 is divided into a first electrode chamber 40 a provided with a first power supply body 41 and a second electrode chamber 40 b provided with a second power supply body 42 by a diaphragm 43.

第一供電體41以及第二供電體42的極性和施加於第一供電體41以及第二供電體42的電壓由控制部13進行控制。The polarities of the first power supply 41 and the second power supply 42 and the voltage applied to the first power supply 41 and the second power supply 42 are controlled by the control unit 13.

在供電體41、42與控制部13之間的電流供給線,設置有電流檢測器。電流檢測器對供給至第一供電體41、第二供電體42的電解電流進行檢測,並將相當於其值的電信號輸出至控制部13。The current supply line between the power supply bodies 41 and 42 and the control unit 13 is provided with a current detector. The current detector detects the electrolysis current supplied to the first power supply body 41 and the second power supply body 42 and outputs an electric signal corresponding to the value to the control unit 13.

控制部13例如根據從電流檢測器輸出的電信號來控制施加於第一供電體41以及第二供電體42的直流電壓。更具體而言,控制部13對施加於第一供電體41以及第二供電體42的直流電壓進行反饋控制,以使由電流檢測器檢測的電解電流成為預先設定的期望的值。例如,在電解電流過大的情況下,控制部13使上述電壓減少,在電解電流過小的情況下,控制部13使上述電壓增加。由此,對供給至第一供電體41以及第二供電體42的電解電流適當地進行控制。The control unit 13 controls the DC voltage applied to the first power supply body 41 and the second power supply body 42 based on the electrical signal output from the current detector, for example. More specifically, the control unit 13 performs feedback control on the DC voltage applied to the first power supply 41 and the second power supply 42 so that the electrolysis current detected by the current detector becomes a predetermined desired value. For example, when the electrolysis current is too large, the control unit 13 reduces the above-mentioned voltage, and when the electrolysis current is too small, the control unit 13 increases the above-mentioned voltage. Thereby, the electrolysis current supplied to the first power supply body 41 and the second power supply body 42 is appropriately controlled.

通過在電解室40內中對水進行電解來產生氫氣以及氧氣。例如,在陰極側的第二極室40b中產生氫氣,並生成溶入有該氫分子的溶氫水,且將該溶氫水供給至反滲透膜處理裝置2的反滲透膜模塊23。此外,伴隨這樣的電解而生成的溶氫水也稱為“電解氫水”,使用電解氫水的透析治療也稱為“電解水透析”。另一方面,在陽極側的第一極室40a中產生氧氣。Hydrogen and oxygen are generated by electrolyzing water in the electrolysis chamber 40. For example, hydrogen gas is generated in the second electrode chamber 40b on the cathode side, and hydrogen-dissolved water in which the hydrogen molecules are dissolved is generated, and the hydrogen-dissolved water is supplied to the reverse osmosis membrane module 23 of the reverse osmosis membrane treatment device 2. In addition, the hydrogen-dissolved water produced with such electrolysis is also called "electrolyzed hydrogen water", and the dialysis treatment using electrolyzed hydrogen water is also called "electrolyzed water dialysis". On the other hand, oxygen is generated in the first electrode chamber 40a on the anode side.

隔膜43例如酌情採用由具有磺酸基的氟系樹脂構成的固體高分子膜。固體高分子膜通過電解使在陽極側的第一極室40a中產生的氧鎓離子向陰極側的第二極室40b移動來作為氫氣的生成原料。因此,在電解時不產生氫氧化物離子,溶氫水的pH不變化。As the separator 43, for example, a solid polymer film made of a fluorine-based resin having a sulfonic acid group is used as appropriate. The solid polymer membrane uses electrolysis to move oxonium ions generated in the first electrode chamber 40a on the anode side to the second electrode chamber 40b on the cathode side as a raw material for hydrogen generation. Therefore, no hydroxide ions are generated during electrolysis, and the pH of the hydrogen-dissolved water does not change.

在本實施方式中,控制部13優選構成為:根據由檢測部12檢測到的呼氣的每單位體積的氫氣的量來控制供給至第一供電體41以及第二供電體42的用於電解的電流,以使溶氫水的溶氫濃度變大或變小。In this embodiment, the control unit 13 is preferably configured to control the amount of hydrogen supplied to the first power supply body 41 and the second power supply body 42 for electrolysis based on the amount of hydrogen per unit volume of the exhaled breath detected by the detection unit 12 The current to make the dissolved hydrogen concentration of the hydrogen-dissolved water increase or decrease.

更具體而言,在由檢測部12檢測到的呼氣的每單位體積的氫氣的量小於預先設定的閾值時,控制部13將供給至第一供電體41以及第二供電體42的用於電解的電流控制得較大。另一方面,在上述氫氣的量大於預先設定的閾值時,控制部13將供給至第一供電體41以及第二供電體42的用於電解的電流控制得較小。More specifically, when the amount of hydrogen per unit volume of the expiration detected by the detection unit 12 is less than a preset threshold, the control unit 13 will supply to the first power supply 41 and the second power supply 42 The electrolysis current is controlled to be larger. On the other hand, when the amount of the hydrogen gas is greater than the preset threshold value, the control unit 13 controls the current for electrolysis supplied to the first power supply body 41 and the second power supply body 42 to be small.

另外,在由檢測部12檢測到的上述氫氣的量的平均值或累積值小於預先設定的閾值時,控制部13可以構成為將供給至第一供電體41以及第二供電體42的用於電解的電流控制得較大。另一方面,在上述氫氣的量的平均值或累積值大於預先設定的閾值時,控制部13可以將供給至第一供電體41以及第二供電體42的用於電解的電流控制得較小。In addition, when the average value or the cumulative value of the hydrogen gas amount detected by the detection unit 12 is less than a preset threshold value, the control unit 13 may be configured to supply the power supply to the first power supply body 41 and the second power supply body 42. The electrolysis current is controlled to be larger. On the other hand, when the average value or cumulative value of the amount of hydrogen is greater than a preset threshold, the control unit 13 can control the current supplied to the first power supply body 41 and the second power supply body 42 for electrolysis to be small. .

另外,控制部13可以構成為:根據呼氣的每單位體積的氫氣的量的平均值以及累積值的組合,將供給至第一供電體41以及第二供電體42的用於電解的電流控制得較大。In addition, the control unit 13 may be configured to control the current for electrolysis supplied to the first power supply body 41 and the second power supply body 42 based on the combination of the average value and the cumulative value of the amount of hydrogen per unit volume of exhalation. It's bigger.

圖3示出了用於本溶氫水生成裝置1的溶氫水生成方法500的處理過程。溶氫水生成方法500在採用加氫的透析液的透析治療中執行,包含生成工序S1、檢測工序S21、S22以及控制工序S3、S4、S5。FIG. 3 shows the processing process of the hydrogen-dissolved water generating method 500 used in the hydrogen-dissolved water generating device 1. The hydrogen-dissolved water production method 500 is executed in a dialysis treatment using a hydrogenated dialysate, and includes a production step S1, a detection step S21, S22, and a control step S3, S4, and S5.

在生成工序S1中,由氫水生成部3生成溶氫水。在透析治療的執行過程中,原則上持續進行溶氫水的生成。In the production step S1, the hydrogen-dissolved water is produced by the hydrogen-water production unit 3. During the execution of dialysis treatment, in principle, the generation of hydrogen-dissolved water is continued.

在檢測工序S21中,安裝於患者H的嘴角的採集部11採集透析中的患者H的呼氣。在檢測工序S22中,檢測部12檢測在檢測工序S21中採集的呼氣中所含的氫氣。在控制工序S3、S4中,控制部13根據檢測工序S22中的檢測結果(氫氣的有無)來控制氫水生成部3。即,在從呼氣中檢測到氫氣的情況下(在S3中為“是”),能判斷氫氣已遍及患者H的體內,因此使氫水生成部3的動作減弱或停止(S4)。例如,在控制工序S4中,控制部13減弱或切斷用於電解的電流。In the detection step S21, the collection unit 11 attached to the corner of the mouth of the patient H collects the breath of the patient H during dialysis. In the detection step S22, the detection unit 12 detects the hydrogen contained in the breath collected in the detection step S21. In the control steps S3 and S4, the control unit 13 controls the hydrogen water generator 3 based on the detection result (the presence or absence of hydrogen) in the detection step S22. That is, when hydrogen gas is detected from the breath (Yes in S3), it can be judged that the hydrogen gas has spread throughout the body of the patient H, and therefore the operation of the hydrogen water generator 3 is weakened or stopped (S4). For example, in the control step S4, the control unit 13 weakens or cuts off the current used for electrolysis.

另一方面,在未從呼氣中檢測到氫氣的情況下(在S3中為“否”),控制氫水生成部3的動作(S5)以使溶氫濃度變大,並返回到S21。例如,在控制工序S5中,控制部13使用於電解的電流變大。On the other hand, when hydrogen is not detected from the breath (No in S3), the operation of the hydrogen water generator 3 is controlled (S5) to increase the dissolved hydrogen concentration, and the process returns to S21. For example, in the control step S5, the current used by the control unit 13 for electrolysis increases.

根據本溶氫水生成方法500,能根據送至患者H的體內的氫來適當地控制用於透析液的製備的溶氫水的生成。According to the present hydrogen-dissolved water production method 500, the production of hydrogen-dissolved water used for the preparation of dialysate can be appropriately controlled based on the hydrogen delivered to the body of the patient H.

圖4示出了作為圖3的溶氫水生成方法500的變形例的溶氫水生成方法500A。關於溶氫水生成方法500A當中的以下未說明的部分,能採用上述溶氫水生成方法500的處理過程。FIG. 4 shows a hydrogen-dissolved water generating method 500A as a modification of the hydrogen-dissolved water generating method 500 of FIG. 3. Regarding the parts not described below in the hydrogen-dissolved water generating method 500A, the treatment process of the above-mentioned hydrogen-dissolved water generating method 500 can be adopted.

在溶氫水生成方法500A中,在應用溶氫水生成方法500的控制工序S3、S4、S5的基礎上還應用控制工序S31、S32。在控制工序S3、S31、S32、S4、S5中,控制部13根據檢測工序S22中的檢測結果,計算呼氣的每單位體積的氫氣的量,從而控制氫水生成部3的動作。In the hydrogen-dissolved water production method 500A, the control steps S31 and S32 are applied in addition to the control steps S3, S4, and S5 of the hydrogen-dissolved water production method 500. In the control steps S3, S31, S32, S4, and S5, the control unit 13 calculates the amount of hydrogen gas per unit volume of exhalation based on the detection result in the detection step S22 to control the operation of the hydrogen water generator 3.

即,在控制工序S3中從呼氣中檢測到氫氣的情況下(在S3中為“是”),轉移至控制工序S31。在控制工序S31中,控制部13根據檢測工序S22中的檢測結果來計算呼氣的每單位體積的氫氣的量。而且,在氫氣的量為第一閾值以上的情況下(在S32中為“是”),轉移至S4。可以構成為:在執行S4後,返回到S21。That is, when hydrogen gas is detected from the breath in the control step S3 (YES in S3), the process proceeds to the control step S31. In the control step S31, the control unit 13 calculates the amount of hydrogen per unit volume of the breath based on the detection result in the detection step S22. Then, when the amount of hydrogen is equal to or greater than the first threshold value (YES in S32), the process proceeds to S4. It can be configured to return to S21 after executing S4.

另一方面,在氫氣的量小於第一閾值的情況下(在S32中為“否”),轉移至S5後,返回到S21。在溶氫水生成方法500A中,控制部13根據呼氣中的氫氣的濃度來控制氫水生成部3的動作,因此能適當地控制用於透析液的製備的溶氫水的生成。On the other hand, when the amount of hydrogen is less than the first threshold value (No in S32), after shifting to S5, it returns to S21. In the hydrogen-dissolved water production method 500A, the control unit 13 controls the operation of the hydrogen-water production unit 3 according to the concentration of hydrogen in the breath, and therefore can appropriately control the production of the hydrogen-dissolved water used for the preparation of the dialysate.

圖5示出了作為圖3的溶氫水生成方法500A的變形例的溶氫水生成方法500B。關於溶氫水生成方法500B當中的以下未說明的部分,能採用上述溶氫水生成方法500A等的處理過程。FIG. 5 shows a hydrogen-dissolved water production method 500B as a modification of the hydrogen-dissolved water production method 500A of FIG. 3. Regarding the parts that are not described below in the hydrogen-dissolved water generating method 500B, the treatment process of the above-mentioned hydrogen-dissolved water generating method 500A and the like can be adopted.

在溶氫水生成方法500B中,應用控制工序S33、S34來代替溶氫水生成方法500A的控制工序S31、S32。在控制工序S3、S33、S34、S4、S5中,控制部13根據檢測工序S22中的檢測結果來計算呼氣的每單位體積的氫氣的量的平均值,並控制氫水生成部3的動作。In the hydrogen-dissolved water production method 500B, the control steps S33 and S34 are applied instead of the control steps S31 and S32 of the hydrogen-dissolved water production method 500A. In the control steps S3, S33, S34, S4, and S5, the control unit 13 calculates the average value of the amount of hydrogen per unit volume of exhalation based on the detection result in the detection step S22, and controls the operation of the hydrogen water generator 3 .

即,在控制工序S3中從呼氣中檢測到氫氣的情況下(在S3中為“是”),轉移至控制工序S33。在控制工序S33中,控制部13根據檢測工序S22中的檢測結果來計算呼氣的每單位體積的氫氣的量的平均值。而且,在氫氣的量的平均值為第二閾值以上的情況下(在S34中為“是”),移動至S4。另一方面,在氫氣的量的平均值小於第二閾值的情況下(在S34中為“否”),移動至S5後,返回到S21。在溶氫水生成方法500B中,根據呼氣中的氫氣的濃度的平均值來控制氫水生成部3的動作,因此不受呼氣中的氫氣的濃度的微小的變動影響,而能適當地控制用於透析液的製備的溶氫水的生成。That is, when hydrogen gas is detected from the breath in the control step S3 (YES in S3), the process proceeds to the control step S33. In the control step S33, the control unit 13 calculates the average value of the amount of hydrogen per unit volume of the breath based on the detection result in the detection step S22. Then, when the average value of the amount of hydrogen is equal to or greater than the second threshold value (YES in S34), the process moves to S4. On the other hand, when the average value of the amount of hydrogen is less than the second threshold value (No in S34), after moving to S5, it returns to S21. In the hydrogen-dissolved water production method 500B, the operation of the hydrogen-water generator 3 is controlled based on the average value of the hydrogen concentration in the exhalation. Therefore, it is not affected by the slight fluctuation of the hydrogen concentration in the exhalation, and can be appropriately Control the generation of hydrogen-dissolved water used in the preparation of dialysate

圖6示出了作為圖3的溶氫水生成方法500A的另一變形例的溶氫水生成方法500C。關於溶氫水生成方法500C當中的以下未說明的部分,能採用上述溶氫水生成方法500A等處理過程。FIG. 6 shows a hydrogen-dissolved water generating method 500C as another modification of the hydrogen-dissolved water generating method 500A of FIG. 3. Regarding the following unexplained parts of the hydrogen-dissolved water production method 500C, treatment processes such as the above-mentioned hydrogen-dissolved water production method 500A can be used.

在溶氫水生成方法500C中,應用控制工序S35、S36來代替溶氫水生成方法500A的控制工序S31、S32。在控制工序S3、S35、S36、S4、S5中,控制部13根據檢測工序S22中的檢測結果來計算呼氣的每單位體積的氫氣的量的累積值,從而控制氫水生成部3的動作。In the hydrogen-dissolved water production method 500C, the control steps S35 and S36 are applied instead of the control steps S31 and S32 of the hydrogen-dissolved water production method 500A. In the control steps S3, S35, S36, S4, and S5, the control unit 13 calculates the cumulative value of the amount of hydrogen per unit volume of exhalation based on the detection result in the detection step S22, thereby controlling the operation of the hydrogen water generator 3 .

即,在控制工序S3中從呼氣中檢測到氫氣的情況下(在S3中為“是”),轉移至控制工序S35。在控制工序S35中,控制部13根據檢測工序S22中的檢測結果來計算上述氫氣的量的累積值。而且,在氫氣的量的累積值為第三閾值以上的情況下(在S35中為“是”),轉移至S4。另一方面,在氫氣的量的累積值小於第三閾值的情況下(在S36中為“否”),轉移至S5後,返回到S21。在溶氫水生成方法500C中,根據氫氣的量的累積值來控制氫水生成部3的動作,因此能根據蓄積於患者H的體內的氫氣來適當地控制用於透析液的製備的溶氫水的生成。That is, when hydrogen gas is detected from the breath in the control step S3 (YES in S3), the process proceeds to the control step S35. In the control step S35, the control unit 13 calculates the cumulative value of the hydrogen gas amount based on the detection result in the detection step S22. Then, when the cumulative value of the amount of hydrogen is equal to or greater than the third threshold (YES in S35), the process proceeds to S4. On the other hand, when the cumulative value of the amount of hydrogen is less than the third threshold (No in S36), after shifting to S5, it returns to S21. In the hydrogen-dissolved water production method 500C, the operation of the hydrogen-water production unit 3 is controlled based on the cumulative value of the amount of hydrogen. Therefore, the hydrogen dissolved in the preparation of the dialysate can be appropriately controlled based on the hydrogen accumulated in the body of the patient H The generation of water.

雖然以上詳細說明了本發明的溶氫水生成裝置1,但本發明不限於上述具體的實施方式而能變更為各種各樣的形態來實施。即,本溶氫水生成裝置1是用於生成在水中溶入有氫而得到的溶氫水的裝置,至少具備生成溶氫水的氫水生成部3、用於使用以溶氫水所製備的透析液來檢測接受透析的患者H的呼氣中所含的氫氣的檢測部12、以及用於根據檢測部12的檢測結果來控制氫水生成部3的控制部13即可。Although the hydrogen-dissolved water generator 1 of the present invention has been described in detail above, the present invention is not limited to the specific embodiment described above, and can be modified and implemented in various forms. That is, the present hydrogen-dissolved water generator 1 is a device for generating hydrogen-dissolved water obtained by dissolving hydrogen in water, and at least is equipped with a hydrogen-dissolved water generating part 3 for generating hydrogen-dissolved water, and is used to produce hydrogen-dissolved water. It is sufficient that the detection unit 12 that detects the hydrogen contained in the breath of the patient H undergoing dialysis and the control unit 13 that controls the hydrogen water generating unit 3 based on the detection result of the detection unit 12 are sufficient.

因此,例如,控制部13也可以構成為:在呼氣的每單位體積的氫氣的量或氫氣的量的上述平均值超過預先設定的第四閾值或第五閾值的情況下,判斷為透析完成。另外,控制部13也可以構成為:在氫氣的量的上述累積值超過預先設定的第六閾值的情況下,判斷為透析完成。Therefore, for example, the control unit 13 may be configured to determine that the dialysis is completed when the amount of hydrogen per unit volume of exhalation or the above average value of the amount of hydrogen exceeds a preset fourth threshold or fifth threshold. . In addition, the control unit 13 may be configured to determine that the dialysis is completed when the cumulative value of the amount of hydrogen exceeds a preset sixth threshold value.

另外,氫水生成部3不限於通過對水進行電解來生成溶氫水的電解槽4,例如可以是使通過水與鎂的化學反應等產生的氫分子溶解於水來生成溶氫水的裝置,或者可以是使從氫氣儲罐供給的氫氣(氫分子)溶解於水來生成溶氫水的裝置。In addition, the hydrogen water generator 3 is not limited to the electrolytic cell 4 that generates hydrogen-dissolved water by electrolyzing water, and may be, for example, a device that dissolves hydrogen molecules generated by the chemical reaction of water and magnesium in water to generate hydrogen-dissolved water. , Or it may be a device that dissolves hydrogen (hydrogen molecules) supplied from a hydrogen storage tank in water to generate hydrogen-dissolved water.

另外,本溶氫水生成方法500等是用於生成在水中溶入有氫而得到的溶氫水的方法,至少包含生成溶氫水的生成工序S1、使用以溶氫水所製備的透析液來檢測接受透析的患者H的呼氣中所含的氫氣的檢測工序S22、以及根據氫氣的檢測結果來控制溶氫水的溶氫濃度的控制工序S3至S5即可。In addition, the present hydrogen-dissolved water production method 500, etc., are methods for producing hydrogen-dissolved water obtained by dissolving hydrogen in water, and include at least the production step S1 of producing hydrogen-dissolved water, using a dialysate prepared with hydrogen-dissolved water The detection step S22 of detecting the hydrogen contained in the breath of the patient H undergoing dialysis and the control steps S3 to S5 of controlling the dissolved hydrogen concentration of the hydrogen-dissolved water based on the detection result of the hydrogen gas may be used.

綜上所述,本發明所揭露之技術手段確能有效解決習知等問題,並達致預期之目的與功效,且申請前未見諸於刊物、未曾公開使用且具長遠進步性,誠屬專利法所稱之發明無誤,爰依法提出申請,懇祈  鈞上惠予詳審並賜准發明專利,至感德馨。In summary, the technical means disclosed in the present invention can effectively solve the conventional problems and achieve the expected purpose and effect. It has not been seen in the publications, has not been used publicly, and has long-term progress before the application. The patent law claims that the invention is correct. Yan filed an application in accordance with the law and prayed that Jun Shanghui would give a detailed examination and grant a patent for invention.

惟以上所述者,僅為本發明之數種較佳實施例,當不能以此限定本發明實施之範圍,即大凡依本發明申請專利範圍及發明說明書內容所作之等效變化與修飾,皆應仍屬本發明專利涵蓋之範圍內。However, the above are only a few preferred embodiments of the present invention, and should not be used to limit the scope of implementation of the present invention, that is, all equivalent changes and modifications made in accordance with the scope of the patent application of the present invention and the content of the description of the invention are all It should still fall within the scope of the invention patent.

〔本發明〕 1:透析判定裝置 100:透析系統 11:採集部 12:檢測部 13:控制部 14:通知部 2:反滲透膜處理裝置 21:軟水化處理裝置 22:活性碳處理裝置 23:反滲透膜模塊 3:氫水生成部 4:電解槽 40:電解室 40a:第一極室 40b:第二極室 41:第一供電體 42:第二供電體 43:隔膜 5:透析液製備裝置 500:溶氫水生成方法 500A:溶氫水生成方法 500B:溶氫水生成方法 500C:溶氫水生成方法 6:透析裝置 61:透析液供給裝置 62:透析器 62a:透析膜 63、64:血液回路 65:泵 S1:生成工序 S21、S22:檢測工序 S3、S4、S5:控制工序 S31、S32、S33、S34、S35、S36:控制工序 H:患者〔this invention〕 1: Dialysis judging device 100: Dialysis system 11: Collection Department 12: Inspection Department 13: Control Department 14: Notification Department 2: Reverse osmosis membrane treatment device 21: Softening treatment device 22: Activated carbon treatment device 23: Reverse osmosis membrane module 3: Hydrogen water generation department 4: Electrolyzer 40: Electrolysis room 40a: first pole chamber 40b: second electrode chamber 41: The first power supply body 42: The second power supply body 43: Diaphragm 5: Dialysate preparation device 500: Hydrogen-dissolved water generation method 500A: Hydrogen-dissolved water generation method 500B: Method of generating dissolved hydrogen water 500C: Hydrogen-dissolved water generation method 6: Dialysis device 61: Dialysate supply device 62: Dialyzer 62a: dialysis membrane 63, 64: blood circuit 65: pump S1: Generation process S21, S22: Inspection process S3, S4, S5: control process S31, S32, S33, S34, S35, S36: control process H: Patient

[圖1]是表示包含本發明的溶氫水生成裝置的透析系統的概略構成的圖; [圖2]是表示作為圖1的溶氫水生成部的一例的電解槽的圖; [圖3]是表示用於圖1的溶氫水生成裝置的溶氫水生成方法的處理過程的流程圖; [圖4]是表示圖3的溶氫水生成方法的變形例的處理過程的流程圖; [圖5]是表示圖4的溶氫水生成方法的另一變形例的處理過程的流程圖; [圖6]是表示圖4的溶氫水生成方法的又一變形例的處理過程的流程圖。[Figure 1] is a diagram showing the schematic configuration of a dialysis system including the hydrogen-dissolved water generator of the present invention; [Figure 2] is a diagram showing an electrolytic cell as an example of the hydrogen-dissolved water generating section of Figure 1; [FIG. 3] is a flowchart showing the processing procedure of the hydrogen-dissolved water generating method used in the hydrogen-dissolved water generating device of FIG. 1; [FIG. 4] is a flowchart showing the processing procedure of a modification of the hydrogen-dissolved water generating method of FIG. 3; [FIG. 5] is a flowchart showing the processing procedure of another modification of the hydrogen-dissolved water generating method of FIG. 4; [Fig. 6] is a flowchart showing a processing procedure of still another modification of the hydrogen-dissolved water production method of Fig. 4.

1:透析判定裝置 1: Dialysis judging device

100:透析系統 100: Dialysis system

11:採集部 11: Collection Department

12:檢測部 12: Inspection Department

13:控制部 13: Control Department

14:通知部 14: Notification Department

2:反滲透膜處理裝置 2: Reverse osmosis membrane treatment device

21:軟水化處理裝置 21: Softening treatment device

22:活性碳處理裝置 22: Activated carbon treatment device

23:反滲透膜模塊 23: Reverse osmosis membrane module

3:氫水生成部 3: Hydrogen water generation department

5:透析液製備裝置 5: Dialysate preparation device

6:透析裝置 6: Dialysis device

61:透析液供給裝置 61: Dialysate supply device

62:透析器 62: Dialyzer

62a:透析膜 62a: dialysis membrane

63、64:血液回路 63, 64: blood circuit

65:泵 65: pump

H:患者 H: Patient

Claims (9)

一種溶氫水生成裝置,用於生成在水中溶入有氫而得到的溶氫水, 所述溶氫水生成裝置具備: 氫水生成部,生成所述溶氫水; 檢測部,用於使用以所述溶氫水所製備的透析液來檢測接受透析的患者的呼氣中所含的氫氣;以及 控制部,用於根據所述檢測部的檢測結果來控制所述氫水生成部。A hydrogen-dissolved water generator for generating hydrogen-dissolved water obtained by dissolving hydrogen in water, The hydrogen-dissolved water generator includes: A hydrogen water generating part, which generates the hydrogen-dissolved water; The detection unit is configured to use the dialysate prepared with the hydrogen-dissolved water to detect the hydrogen contained in the breath of the patient undergoing dialysis; and The control unit is configured to control the hydrogen water generating unit based on the detection result of the detection unit. 如請求項1所述之溶氫水生成裝置,其中, 所述控制部根據所述氫氣的有無來控制所述氫水生成部。The hydrogen-dissolved water generating device according to claim 1, wherein: The control unit controls the hydrogen water generating unit based on the presence or absence of the hydrogen gas. 如請求項1所述之溶氫水生成裝置,其中, 所述控制部根據所述呼氣的每單位體積的所述氫氣的量來控制所述氫水生成部。The hydrogen-dissolved water generating device according to claim 1, wherein: The control unit controls the hydrogen water generating unit based on the amount of the hydrogen gas per unit volume of the exhalation. 如請求項3所述之溶氫水生成裝置,其中, 所述控制部根據所述量的平均值來控制所述氫水生成部。The hydrogen-dissolved water generating device according to claim 3, wherein: The control unit controls the hydrogen water generating unit based on the average value of the amount. 如請求項3或4所述之溶氫水生成裝置,其中, 所述控制部根據所述量的累積值來控制所述氫水生成部。The hydrogen-dissolved water generating device according to claim 3 or 4, wherein: The control unit controls the hydrogen water generating unit based on the cumulative value of the amount. 如請求項1至4項中任一項所述之溶氫水生成裝置,其中, 所述溶氫水生成裝置還具備通知部,所述通知部通知所述氫氣的所述量。The hydrogen-dissolved water generating device according to any one of claims 1 to 4, wherein: The hydrogen-dissolved water generating device further includes a notification unit that notifies the amount of the hydrogen gas. 如請求項1至4項中任一項所述之溶氫水生成裝置,其中, 所述氫水生成部包含用於對所述水進行電解的陽極供電體和陰極供電體, 所述控制部控制向所述陽極供電體以及所述陰極供電體供給的用於所述電解的電流,以增大或減小所述溶氫水的溶氫濃度。The hydrogen-dissolved water generating device according to any one of claims 1 to 4, wherein: The hydrogen water generating unit includes an anode power supply body and a cathode power supply body for electrolyzing the water, The control unit controls the current supplied to the anode power supply body and the cathode power supply body for the electrolysis to increase or decrease the dissolved hydrogen concentration of the hydrogen dissolved water. 如請求項3或4所述之溶氫水生成裝置,其中, 所述氫水生成部包含用於對所述水進行電解的陽極供電體和陰極供電體,在所述量小於預先設定的閾值時,所述控制部增大向所述陽極供電體以及所述陰極供電體供給的用於所述電解的電流。The hydrogen-dissolved water generating device according to claim 3 or 4, wherein: The hydrogen water generating unit includes an anode power supply body and a cathode power supply body for electrolyzing the water, and when the amount is less than a preset threshold value, the control unit increases the power supply to the anode power supply body and the The current supplied by the cathode power supply body for the electrolysis. 一種溶氫水生成方法,用於生成在水中溶入有氫而得到的溶氫水, 所述溶氫水生成方法包含: 生成工序,生成所述溶氫水; 檢測工序,使用以所述溶氫水所製備的透析液,來檢測接受透析的患者的呼氣中所含的氫氣;以及 控制工序,根據所述氫氣的檢測結果,來控制所述溶氫水的溶氫濃度。A method for generating hydrogen-dissolved water, used to generate hydrogen-dissolved water obtained by dissolving hydrogen in water, The method for generating hydrogen-dissolved water includes: Generating process, generating the hydrogen-dissolved water; In the detection process, the dialysate prepared with the hydrogen-dissolved water is used to detect the hydrogen contained in the breath of the patient undergoing dialysis; and The control step controls the dissolved hydrogen concentration of the hydrogen-dissolved water based on the detection result of the hydrogen gas.
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