TW202108190A - Hydrogen-dissolved water generating device and hydrogen-dissolved water generating method - Google Patents
Hydrogen-dissolved water generating device and hydrogen-dissolved water generating method Download PDFInfo
- Publication number
- TW202108190A TW202108190A TW109108996A TW109108996A TW202108190A TW 202108190 A TW202108190 A TW 202108190A TW 109108996 A TW109108996 A TW 109108996A TW 109108996 A TW109108996 A TW 109108996A TW 202108190 A TW202108190 A TW 202108190A
- Authority
- TW
- Taiwan
- Prior art keywords
- hydrogen
- dissolved water
- water
- dissolved
- water generating
- Prior art date
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
Landscapes
- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Emergency Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Vascular Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- External Artificial Organs (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Description
本發明涉及用於生成在透析液的製備中使用的溶氫水的溶氫水生成裝置以及溶氫水生成方法。The present invention relates to a hydrogen-dissolved water generating device and a hydrogen-dissolved water generating method for generating hydrogen-dissolved water used in the preparation of dialysate.
在血液透析治療中,採用溶入有氫的溶氫水所製備的透析液有助於降低患者的氧化應激,因此近年備受關注(例如,參照專利文獻1)。In hemodialysis treatment, a dialysate prepared using hydrogen-dissolved water in which hydrogen is dissolved helps to reduce the oxidative stress of patients, and therefore has attracted attention in recent years (for example, refer to Patent Document 1).
在先技術文獻Prior Art Literature
專利文獻Patent literature
專利文獻1:JP特開5840248號公報Patent Document 1: JP Patent Laid-Open No. 5840248
有鑑於此,吾等發明人乃潛心進一步研究,並著手進行研發及改良,期以一較佳發明以解決上述問題,且在經過不斷試驗及修改後而有本發明之問世。In view of this, our inventors devoted themselves to further research, and proceeded to develop and improve, hoping to develop a better invention to solve the above problems, and after continuous experimentation and modification, the present invention came out.
(發明要解決的課題)(The problem to be solved by the invention)
在利用上述專利文獻1中所公開的裝置的透析治療中,氫以何種程度被送至患者的體內是不清楚的,期望建立一種根據送至體內的氫來控制溶氫的生成的技術。In the dialysis treatment using the device disclosed in Patent Document 1, it is not clear to what extent hydrogen is delivered to the patient's body, and it is desired to establish a technology for controlling the generation of dissolved hydrogen based on the hydrogen delivered to the body.
本發明鑑於以上事實而提出,主要目的在於,提供一種技術,用於在採用溶氫水的血液透析治療中,根據送至患者的體內的氫來控制溶氫的生成。The present invention is proposed in view of the above facts, and its main purpose is to provide a technique for controlling the generation of dissolved hydrogen based on the hydrogen delivered to the patient's body in hemodialysis treatment using hydrogen-dissolved water.
(用於解決課題的技術方案)(Technical solution to solve the problem)
本發明的第一發明是用於生成在水中溶入有氫而得到的溶氫水的溶氫水生成裝置,所述溶氫水生成裝置具備:氫水生成部,生成所述溶氫水;檢測部,用於使用以所述溶氫水所製備的透析液來檢測接受透析的患者的呼氣中所含的氫氣;控制部,用於根據所述檢測部的檢測結果來控制所述氫水生成部,以增大或減小所述溶氫水的溶氫濃度。The first invention of the present invention is a hydrogen-dissolved water generating device for generating hydrogen-dissolved water obtained by dissolving hydrogen in water, the hydrogen-dissolved water generating device including: a hydrogen water generating unit that generates the hydrogen-dissolved water; The detection unit is used to detect the hydrogen contained in the breath of the patient undergoing dialysis using the dialysate prepared with the hydrogen-dissolved water; the control unit is used to control the hydrogen according to the detection result of the detection unit The water generating part is used to increase or decrease the dissolved hydrogen concentration of the hydrogen dissolved water.
優選地,在本發明所涉及的所述溶氫水生成裝置中,所述控制部根據所述氫氣的有無來控制所述氫水生成部。Preferably, in the hydrogen-dissolved water generating device according to the present invention, the control unit controls the hydrogen water generating unit according to the presence or absence of the hydrogen gas.
優選地,在本發明所涉及的所述溶氫水生成裝置中,所述控制部根據所述呼氣的每單位體積的所述氫氣的量來控制所述氫水生成部。Preferably, in the hydrogen-dissolved water generating device according to the present invention, the control unit controls the hydrogen water generating unit based on the amount of the hydrogen gas per unit volume of the exhalation.
優選地,在本發明所涉及的所述溶氫水生成裝置中,所述控制部根據所述量的平均值來控制所述氫水生成部。Preferably, in the hydrogen-dissolved water generating device according to the present invention, the control unit controls the hydrogen water generating unit based on an average value of the amount.
優選地,在本發明所涉及的所述溶氫水生成裝置中,所述控制部根據所述量的累積值來控制所述氫水生成部。Preferably, in the hydrogen-dissolved water generating device according to the present invention, the control unit controls the hydrogen water generating unit based on a cumulative value of the amount.
優選地,在本發明所涉及的所述溶氫水生成裝置中,所述溶氫水生成裝置還具備通知部,所述通知部通知所述氫氣的所述量。Preferably, in the hydrogen-dissolved water generating device according to the present invention, the hydrogen-dissolved water generating device further includes a notification unit that notifies the amount of the hydrogen gas.
優選地,在本發明所涉及的所述溶氫水生成裝置中,所述氫水生成部包含用於對所述水進行電解的陽極供電體和陰極供電體,所述控制部控制向所述陽極供電體以及所述陰極供電體供給的用於所述電解的電流,以增大或減小所述溶氫水的溶氫濃度。Preferably, in the hydrogen-dissolved water generating device according to the present invention, the hydrogen-water generating unit includes an anode power supply body and a cathode power supply body for electrolyzing the water, and the control unit controls The current supplied by the anode power supply body and the cathode power supply body for the electrolysis is used to increase or decrease the dissolved hydrogen concentration of the hydrogen dissolved water.
優選地,在本發明所涉及的所述溶氫水生成裝置中,所述氫水生成部包含用於對所述水進行電解的陽極供電體和陰極供電體,在所述量小於預先設定的閾值時,所述控制部增大向所述陽極供電體以及所述陰極供電體供給的用於所述電解的電流。Preferably, in the hydrogen-dissolved water generator according to the present invention, the hydrogen-water generator includes an anode power supply body and a cathode power supply body for electrolyzing the water, and the amount is less than a preset amount. At the threshold value, the control unit increases the current for the electrolysis supplied to the anode power supply body and the cathode power supply body.
本發明的第二發明是一種溶氫水生成方法,用於生成在水中溶入有氫而得到的溶氫水,所述溶氫水生成方法包含:生成工序,通過對所述水進行電解來生成所述溶氫水;檢測工序,使用以所述溶氫水中所製備的透析液來檢測接受透析的患者的呼氣中所含的氫氣;以及控制工序,根據所述氫氣的檢測結果來控制所述溶氫水的溶氫濃度。The second invention of the present invention is a hydrogen-dissolved water generating method for generating hydrogen-dissolved water obtained by dissolving hydrogen in water. The hydrogen-dissolved water generating method includes a generating step of electrolyzing the water. Generating the hydrogen-dissolved water; a detection step of using the dialysate prepared from the hydrogen-dissolved water to detect hydrogen contained in the breath of a patient undergoing dialysis; and a control step of controlling based on the detection result of the hydrogen The dissolved hydrogen concentration of the hydrogen-dissolved water.
(發明效果)(Inventive effect)
本第一發明的所述溶氫水生成裝置具備:所述檢測部,檢測所述透析中的所述患者的所述呼氣中所含的所述氫氣;以及所述控制部,用於根據所述檢測部的檢測結果來控制所述氫水生成部。由此,能根據送至所述患者的體內的所述氫來適當地控制用於所述透析液的製備的所述溶氫水的生成。The hydrogen-dissolved water generating device according to the first aspect of the present invention includes: the detection unit that detects the hydrogen contained in the exhalation of the patient during the dialysis; and the control unit for detecting the The detection result of the detection unit controls the hydrogen water generating unit. Thus, the production of the hydrogen-dissolved water used for the preparation of the dialysate can be appropriately controlled based on the hydrogen delivered to the patient's body.
本第二發明的所述溶氫水生成方法包含:所述檢測工序,檢測所述透析中的患者的呼氣中所含的所述氫氣;以及控制工序,根據所述氫氣的所述檢測結果來控制所述溶氫水的溶氫濃度。由此,能根據送至所述患者的體內的所述氫來適當地控制用於所述透析液的製備的所述溶氫水的溶氫濃度。The method for producing hydrogen-dissolved water according to the second aspect of the present invention includes: the detecting step, detecting the hydrogen contained in the breath of the patient during dialysis; and a controlling step, based on the detection result of the hydrogen To control the dissolved hydrogen concentration of the hydrogen-dissolved water. Thereby, the dissolved hydrogen concentration of the hydrogen-dissolved water used for the preparation of the dialysate can be appropriately controlled based on the hydrogen delivered to the patient's body.
關於吾等發明人之技術手段,茲舉數種較佳實施例配合圖式於下文進行詳細說明,俾供 鈞上深入瞭解並認同本發明。Regarding the technical means of our inventors, several preferred embodiments are described in detail below in conjunction with the drawings, in order to provide a thorough understanding and approval of the present invention.
以下,基於附圖來說明本發明的一實施方式。Hereinafter, an embodiment of the present invention will be described based on the drawings.
圖1示出了包含本實施方式的溶氫水生成裝置1的透析系統100的概略構成。溶氫水生成裝置1是在使用以溶氫水所製備的透析液的透析系統100中用於生成溶氫水的裝置。Fig. 1 shows a schematic configuration of a
透析系統100包含反滲透膜處理裝置2、溶氫水生成裝置1、透析液製備裝置5以及透析裝置6。The
反滲透膜處理裝置2通過反滲透處理對原水進行淨化,並供給至溶氫水生成裝置1。雖然原水一般採用自來水,但除此以外,能使用其他水,例如,井水、地下水等。The reverse osmosis
反滲透膜處理裝置2包含軟水化處理裝置21、活性碳處理裝置22以及反滲透膜模塊23。軟水化處理裝置21從原水中去除鈣離子以及鎂離子等的硬度成分而軟水化。活性碳處理裝置22具有作為微細的多孔質物質的活性碳,從軟水化處理裝置21供給的水中吸附或去除氯等。反滲透膜模塊23將從活性碳處理裝置22供給的水分離為由反滲透膜進行淨化後的處理水與包含雜質的濃縮水。由反滲透膜模塊23淨化後的處理水送至溶氫水生成裝置1。另一方面,未能透過反滲透膜的濃縮水排出至反滲透膜處理裝置2的外部。The reverse osmosis
溶氫水生成裝置1在由反滲透膜處理裝置2淨化處理後的水中加氫而生成溶氫水。溶氫水生成裝置1包含用於生成溶入有氫氣的溶氫水(含氫水)的氫水生成部3。在本實施方式中,應用了電解槽4作為氫水生成部3的一部分。關於電解槽4的細節將後述。由氫水生成部3生成的溶氫水作為透析液製備用水而被送至透析液製備裝置5。The hydrogen-dissolved water generator 1 hydrogenates the water purified by the reverse osmosis
透析液製備裝置5使用從氫水生成部3供給的透析液製備用水,例如對液狀的透析原劑進行稀釋來製備透析液。由透析液製備裝置5製備的透析液被送至透析裝置6。The
透析裝置6包含透析液供給裝置61和透析器62。透析液供給裝置61將從透析液製備裝置5供給的透析液送出至透析器62。透析器62例如是包含由中空纖維等多孔質膜構成的透析膜62a的人工腎臟,使經由透析膜62a從透析液製備裝置5供給的透析液作用於接受透析治療的患者H的血液,從血液中去除代謝廢物以及水分。The dialysis device 6 includes a
患者H與透析器62通過血液回路63、64進行連接。血液回路63將從患者H採集的血液送至透析器62。在血液回路63設置有用於送出血液的泵65。血液回路64使由透析器62去除代謝廢物等後的血液返回患者H。The patient H and the dialyzer 62 are connected through
溶氫水生成裝置1除具備上述氫水生成部3以外,還具備用於採集患者H的呼氣的採集部11、用於檢測患者H的呼氣中所含的氫氣的檢測部12以及用於控制氫水生成部3的控制部13。The hydrogen-dissolved water generating device 1 includes, in addition to the above-mentioned hydrogen
採集部11安裝於患者H的鼻子以及嘴角,採集患者H的呼氣並送到檢測部12。The
檢測部12檢測患者H的呼氣中所含的的氫氣的量,且將對應的電信號輸出至控制部13。檢測部12能採用已知的氫氣探測器等。在採用能從患者H的口內等的呼氣中檢測氫氣的檢測部12的形態中,採集部11是不需要的。The
控制部13例如由具有執行各種運算處理、信息處理等的CPU(Central Processing Unit)以及對負責CPU的動作的程序以及各種信息進行存儲的存儲器等構成。控制部13負責溶氫水生成裝置1的各部的控制。The
更具體而言,控制部13根據從檢測部12輸入的電信號,即,檢測部12的檢測結果,來控制氫水生成部3。例如,在從患者H的呼氣中檢測到氫氣的情況下,能確認由氫水生成部3附加的氫通過透析液以及血液確切地遍及患者H的體內而被吸收,因此使氫水生成部3的動作減弱或停止。More specifically, the
另一方面,在未從患者H的呼氣中檢測到氫氣的情況下,能確認氫還未遍及患者H的體內,因此例如繼續氫水生成部3的動作,即,溶氫水的生成。在此情況下,控制部13也可以控制氫水生成部3的動作以增大溶氫濃度。On the other hand, if hydrogen is not detected in the breath of the patient H, it can be confirmed that the hydrogen has not spread throughout the body of the patient H. Therefore, for example, the operation of the hydrogen
因此,根據溶氫水生成裝置1,能根據送至患者H的體內的氫來適當地控制用於透析液的製備的溶氫水的生成。Therefore, according to the hydrogen-dissolved water generator 1, it is possible to appropriately control the production of hydrogen-dissolved water used for the preparation of the dialysate in accordance with the hydrogen delivered to the body of the patient H.
在本溶氫水生成裝置1中,優選構成為:檢測部12檢測呼氣的每單位體積的氫氣的量,控制部13根據由檢測部12檢測出的氫氣的量來控制氫水生成部3。例如,控制部13通過計算呼氣的每單位體積的氫氣的量,並與預先設定的第一閾值進行比較,從而適當地控制氫水生成部3。第一閾值例如能通過以統計的方式處理與患者H的症狀的推移相關的信息來規定(以下,關於第二閾值至第六閾值也相同)。在這樣的構成中,能根據呼氣中的氫氣的濃度來適當地控制氫水生成部3。In the present hydrogen-dissolved water generating device 1, it is preferable that the detecting
此外,作為上述氫氣的量,除了質量以外,也可以是體積、分子量等。另外,控制部13也可以構成為計算患者H單位時間呼出的呼氣中所含的氫氣的量。In addition, as the amount of the above-mentioned hydrogen, in addition to mass, volume, molecular weight, etc. may also be used. In addition, the
另外,在本溶氫水生成裝置1中,控制部13也可以構成為根據呼氣的每單位體積的氫氣的量來控制氫水生成部3。例如,控制部13通過計算呼氣的每單位體積的氫氣的量的平均值並與預先設定的第二閾值進行比較,從而控制氫水生成部3。控制部13優選計算每段固定時間的移動平均值來作為上述平均值的形態。在這樣的構成中,不受呼氣中的氫氣的濃度的微小的變動影響,能適當地控制氫水生成部3。In addition, in the present hydrogen-dissolved water generator 1, the
另外,在本溶氫水生成裝置1中,控制部13也可以構成為根據由檢測部12檢測出的氫氣的量的累積值來控制氫水生成部3。例如,控制部13通過計算由檢測部12檢測到的氫氣的量的累積值,並與預先設定的第三閾值進行比較,從而控制氫水生成部3。在這樣的構成中,能根據蓄積於患者H的體內的氫氣來適當地控制氫水生成部3。In addition, in the present hydrogen-dissolved water generating device 1, the
在本溶氫水生成裝置1中,優選還具備通知部14,通知部14通知氫氣的量。通知部14例如除了採用輸出光信號的LED等以外,還採用輸出聲音信號的揚聲器裝置等。通知也可以兼用光信號和聲音信號。通知部14的動作例如由控制部13控制。通過在溶氫水生成裝置1中設置通知部14,醫師、護士或患者H能通過通知部14得知氫已到達患者H的體內。In the present hydrogen-dissolved water generating device 1, it is preferable to further include a
圖2示出了構成氫水生成部3的電解槽4。電解槽4通過對水進行電解來產生氫分子。通過使該氫分子溶入於水,來生成附加有第一氫的水即溶氫水。FIG. 2 shows the electrolytic cell 4 constituting the hydrogen
電解槽4具備電解室40,在電解室40內具有第一供電體41和第二供電體42。第一供電體41以及第二供電體42設置於電解室40。The electrolysis tank 4 includes an
在第一供電體41與第二供電體42之間設置有隔膜43。電解室40通過隔膜43而被劃分為配有第一供電體41的第一極室40a和配有第二供電體42的第二極室40b。A diaphragm 43 is provided between the first
第一供電體41以及第二供電體42的極性和施加於第一供電體41以及第二供電體42的電壓由控制部13進行控制。The polarities of the
在供電體41、42與控制部13之間的電流供給線,設置有電流檢測器。電流檢測器對供給至第一供電體41、第二供電體42的電解電流進行檢測,並將相當於其值的電信號輸出至控制部13。The current supply line between the
控制部13例如根據從電流檢測器輸出的電信號來控制施加於第一供電體41以及第二供電體42的直流電壓。更具體而言,控制部13對施加於第一供電體41以及第二供電體42的直流電壓進行反饋控制,以使由電流檢測器檢測的電解電流成為預先設定的期望的值。例如,在電解電流過大的情況下,控制部13使上述電壓減少,在電解電流過小的情況下,控制部13使上述電壓增加。由此,對供給至第一供電體41以及第二供電體42的電解電流適當地進行控制。The
通過在電解室40內中對水進行電解來產生氫氣以及氧氣。例如,在陰極側的第二極室40b中產生氫氣,並生成溶入有該氫分子的溶氫水,且將該溶氫水供給至反滲透膜處理裝置2的反滲透膜模塊23。此外,伴隨這樣的電解而生成的溶氫水也稱為“電解氫水”,使用電解氫水的透析治療也稱為“電解水透析”。另一方面,在陽極側的第一極室40a中產生氧氣。Hydrogen and oxygen are generated by electrolyzing water in the
隔膜43例如酌情採用由具有磺酸基的氟系樹脂構成的固體高分子膜。固體高分子膜通過電解使在陽極側的第一極室40a中產生的氧鎓離子向陰極側的第二極室40b移動來作為氫氣的生成原料。因此,在電解時不產生氫氧化物離子,溶氫水的pH不變化。As the separator 43, for example, a solid polymer film made of a fluorine-based resin having a sulfonic acid group is used as appropriate. The solid polymer membrane uses electrolysis to move oxonium ions generated in the first electrode chamber 40a on the anode side to the
在本實施方式中,控制部13優選構成為:根據由檢測部12檢測到的呼氣的每單位體積的氫氣的量來控制供給至第一供電體41以及第二供電體42的用於電解的電流,以使溶氫水的溶氫濃度變大或變小。In this embodiment, the
更具體而言,在由檢測部12檢測到的呼氣的每單位體積的氫氣的量小於預先設定的閾值時,控制部13將供給至第一供電體41以及第二供電體42的用於電解的電流控制得較大。另一方面,在上述氫氣的量大於預先設定的閾值時,控制部13將供給至第一供電體41以及第二供電體42的用於電解的電流控制得較小。More specifically, when the amount of hydrogen per unit volume of the expiration detected by the
另外,在由檢測部12檢測到的上述氫氣的量的平均值或累積值小於預先設定的閾值時,控制部13可以構成為將供給至第一供電體41以及第二供電體42的用於電解的電流控制得較大。另一方面,在上述氫氣的量的平均值或累積值大於預先設定的閾值時,控制部13可以將供給至第一供電體41以及第二供電體42的用於電解的電流控制得較小。In addition, when the average value or the cumulative value of the hydrogen gas amount detected by the
另外,控制部13可以構成為:根據呼氣的每單位體積的氫氣的量的平均值以及累積值的組合,將供給至第一供電體41以及第二供電體42的用於電解的電流控制得較大。In addition, the
圖3示出了用於本溶氫水生成裝置1的溶氫水生成方法500的處理過程。溶氫水生成方法500在採用加氫的透析液的透析治療中執行,包含生成工序S1、檢測工序S21、S22以及控制工序S3、S4、S5。FIG. 3 shows the processing process of the hydrogen-dissolved
在生成工序S1中,由氫水生成部3生成溶氫水。在透析治療的執行過程中,原則上持續進行溶氫水的生成。In the production step S1, the hydrogen-dissolved water is produced by the hydrogen-
在檢測工序S21中,安裝於患者H的嘴角的採集部11採集透析中的患者H的呼氣。在檢測工序S22中,檢測部12檢測在檢測工序S21中採集的呼氣中所含的氫氣。在控制工序S3、S4中,控制部13根據檢測工序S22中的檢測結果(氫氣的有無)來控制氫水生成部3。即,在從呼氣中檢測到氫氣的情況下(在S3中為“是”),能判斷氫氣已遍及患者H的體內,因此使氫水生成部3的動作減弱或停止(S4)。例如,在控制工序S4中,控制部13減弱或切斷用於電解的電流。In the detection step S21, the
另一方面,在未從呼氣中檢測到氫氣的情況下(在S3中為“否”),控制氫水生成部3的動作(S5)以使溶氫濃度變大,並返回到S21。例如,在控制工序S5中,控制部13使用於電解的電流變大。On the other hand, when hydrogen is not detected from the breath (No in S3), the operation of the
根據本溶氫水生成方法500,能根據送至患者H的體內的氫來適當地控制用於透析液的製備的溶氫水的生成。According to the present hydrogen-dissolved
圖4示出了作為圖3的溶氫水生成方法500的變形例的溶氫水生成方法500A。關於溶氫水生成方法500A當中的以下未說明的部分,能採用上述溶氫水生成方法500的處理過程。FIG. 4 shows a hydrogen-dissolved
在溶氫水生成方法500A中,在應用溶氫水生成方法500的控制工序S3、S4、S5的基礎上還應用控制工序S31、S32。在控制工序S3、S31、S32、S4、S5中,控制部13根據檢測工序S22中的檢測結果,計算呼氣的每單位體積的氫氣的量,從而控制氫水生成部3的動作。In the hydrogen-dissolved
即,在控制工序S3中從呼氣中檢測到氫氣的情況下(在S3中為“是”),轉移至控制工序S31。在控制工序S31中,控制部13根據檢測工序S22中的檢測結果來計算呼氣的每單位體積的氫氣的量。而且,在氫氣的量為第一閾值以上的情況下(在S32中為“是”),轉移至S4。可以構成為:在執行S4後,返回到S21。That is, when hydrogen gas is detected from the breath in the control step S3 (YES in S3), the process proceeds to the control step S31. In the control step S31, the
另一方面,在氫氣的量小於第一閾值的情況下(在S32中為“否”),轉移至S5後,返回到S21。在溶氫水生成方法500A中,控制部13根據呼氣中的氫氣的濃度來控制氫水生成部3的動作,因此能適當地控制用於透析液的製備的溶氫水的生成。On the other hand, when the amount of hydrogen is less than the first threshold value (No in S32), after shifting to S5, it returns to S21. In the hydrogen-dissolved
圖5示出了作為圖3的溶氫水生成方法500A的變形例的溶氫水生成方法500B。關於溶氫水生成方法500B當中的以下未說明的部分,能採用上述溶氫水生成方法500A等的處理過程。FIG. 5 shows a hydrogen-dissolved
在溶氫水生成方法500B中,應用控制工序S33、S34來代替溶氫水生成方法500A的控制工序S31、S32。在控制工序S3、S33、S34、S4、S5中,控制部13根據檢測工序S22中的檢測結果來計算呼氣的每單位體積的氫氣的量的平均值,並控制氫水生成部3的動作。In the hydrogen-dissolved
即,在控制工序S3中從呼氣中檢測到氫氣的情況下(在S3中為“是”),轉移至控制工序S33。在控制工序S33中,控制部13根據檢測工序S22中的檢測結果來計算呼氣的每單位體積的氫氣的量的平均值。而且,在氫氣的量的平均值為第二閾值以上的情況下(在S34中為“是”),移動至S4。另一方面,在氫氣的量的平均值小於第二閾值的情況下(在S34中為“否”),移動至S5後,返回到S21。在溶氫水生成方法500B中,根據呼氣中的氫氣的濃度的平均值來控制氫水生成部3的動作,因此不受呼氣中的氫氣的濃度的微小的變動影響,而能適當地控制用於透析液的製備的溶氫水的生成。That is, when hydrogen gas is detected from the breath in the control step S3 (YES in S3), the process proceeds to the control step S33. In the control step S33, the
圖6示出了作為圖3的溶氫水生成方法500A的另一變形例的溶氫水生成方法500C。關於溶氫水生成方法500C當中的以下未說明的部分,能採用上述溶氫水生成方法500A等處理過程。FIG. 6 shows a hydrogen-dissolved
在溶氫水生成方法500C中,應用控制工序S35、S36來代替溶氫水生成方法500A的控制工序S31、S32。在控制工序S3、S35、S36、S4、S5中,控制部13根據檢測工序S22中的檢測結果來計算呼氣的每單位體積的氫氣的量的累積值,從而控制氫水生成部3的動作。In the hydrogen-dissolved
即,在控制工序S3中從呼氣中檢測到氫氣的情況下(在S3中為“是”),轉移至控制工序S35。在控制工序S35中,控制部13根據檢測工序S22中的檢測結果來計算上述氫氣的量的累積值。而且,在氫氣的量的累積值為第三閾值以上的情況下(在S35中為“是”),轉移至S4。另一方面,在氫氣的量的累積值小於第三閾值的情況下(在S36中為“否”),轉移至S5後,返回到S21。在溶氫水生成方法500C中,根據氫氣的量的累積值來控制氫水生成部3的動作,因此能根據蓄積於患者H的體內的氫氣來適當地控制用於透析液的製備的溶氫水的生成。That is, when hydrogen gas is detected from the breath in the control step S3 (YES in S3), the process proceeds to the control step S35. In the control step S35, the
雖然以上詳細說明了本發明的溶氫水生成裝置1,但本發明不限於上述具體的實施方式而能變更為各種各樣的形態來實施。即,本溶氫水生成裝置1是用於生成在水中溶入有氫而得到的溶氫水的裝置,至少具備生成溶氫水的氫水生成部3、用於使用以溶氫水所製備的透析液來檢測接受透析的患者H的呼氣中所含的氫氣的檢測部12、以及用於根據檢測部12的檢測結果來控制氫水生成部3的控制部13即可。Although the hydrogen-dissolved water generator 1 of the present invention has been described in detail above, the present invention is not limited to the specific embodiment described above, and can be modified and implemented in various forms. That is, the present hydrogen-dissolved water generator 1 is a device for generating hydrogen-dissolved water obtained by dissolving hydrogen in water, and at least is equipped with a hydrogen-dissolved
因此,例如,控制部13也可以構成為:在呼氣的每單位體積的氫氣的量或氫氣的量的上述平均值超過預先設定的第四閾值或第五閾值的情況下,判斷為透析完成。另外,控制部13也可以構成為:在氫氣的量的上述累積值超過預先設定的第六閾值的情況下,判斷為透析完成。Therefore, for example, the
另外,氫水生成部3不限於通過對水進行電解來生成溶氫水的電解槽4,例如可以是使通過水與鎂的化學反應等產生的氫分子溶解於水來生成溶氫水的裝置,或者可以是使從氫氣儲罐供給的氫氣(氫分子)溶解於水來生成溶氫水的裝置。In addition, the
另外,本溶氫水生成方法500等是用於生成在水中溶入有氫而得到的溶氫水的方法,至少包含生成溶氫水的生成工序S1、使用以溶氫水所製備的透析液來檢測接受透析的患者H的呼氣中所含的氫氣的檢測工序S22、以及根據氫氣的檢測結果來控制溶氫水的溶氫濃度的控制工序S3至S5即可。In addition, the present hydrogen-dissolved
綜上所述,本發明所揭露之技術手段確能有效解決習知等問題,並達致預期之目的與功效,且申請前未見諸於刊物、未曾公開使用且具長遠進步性,誠屬專利法所稱之發明無誤,爰依法提出申請,懇祈 鈞上惠予詳審並賜准發明專利,至感德馨。In summary, the technical means disclosed in the present invention can effectively solve the conventional problems and achieve the expected purpose and effect. It has not been seen in the publications, has not been used publicly, and has long-term progress before the application. The patent law claims that the invention is correct. Yan filed an application in accordance with the law and prayed that Jun Shanghui would give a detailed examination and grant a patent for invention.
惟以上所述者,僅為本發明之數種較佳實施例,當不能以此限定本發明實施之範圍,即大凡依本發明申請專利範圍及發明說明書內容所作之等效變化與修飾,皆應仍屬本發明專利涵蓋之範圍內。However, the above are only a few preferred embodiments of the present invention, and should not be used to limit the scope of implementation of the present invention, that is, all equivalent changes and modifications made in accordance with the scope of the patent application of the present invention and the content of the description of the invention are all It should still fall within the scope of the invention patent.
〔本發明〕
1:透析判定裝置
100:透析系統
11:採集部
12:檢測部
13:控制部
14:通知部
2:反滲透膜處理裝置
21:軟水化處理裝置
22:活性碳處理裝置
23:反滲透膜模塊
3:氫水生成部
4:電解槽
40:電解室
40a:第一極室
40b:第二極室
41:第一供電體
42:第二供電體
43:隔膜
5:透析液製備裝置
500:溶氫水生成方法
500A:溶氫水生成方法
500B:溶氫水生成方法
500C:溶氫水生成方法
6:透析裝置
61:透析液供給裝置
62:透析器
62a:透析膜
63、64:血液回路
65:泵
S1:生成工序
S21、S22:檢測工序
S3、S4、S5:控制工序
S31、S32、S33、S34、S35、S36:控制工序
H:患者〔this invention〕
1: Dialysis judging device
100: Dialysis system
11: Collection Department
12: Inspection Department
13: Control Department
14: Notification Department
2: Reverse osmosis membrane treatment device
21: Softening treatment device
22: Activated carbon treatment device
23: Reverse osmosis membrane module
3: Hydrogen water generation department
4: Electrolyzer
40: Electrolysis room
40a:
[圖1]是表示包含本發明的溶氫水生成裝置的透析系統的概略構成的圖; [圖2]是表示作為圖1的溶氫水生成部的一例的電解槽的圖; [圖3]是表示用於圖1的溶氫水生成裝置的溶氫水生成方法的處理過程的流程圖; [圖4]是表示圖3的溶氫水生成方法的變形例的處理過程的流程圖; [圖5]是表示圖4的溶氫水生成方法的另一變形例的處理過程的流程圖; [圖6]是表示圖4的溶氫水生成方法的又一變形例的處理過程的流程圖。[Figure 1] is a diagram showing the schematic configuration of a dialysis system including the hydrogen-dissolved water generator of the present invention; [Figure 2] is a diagram showing an electrolytic cell as an example of the hydrogen-dissolved water generating section of Figure 1; [FIG. 3] is a flowchart showing the processing procedure of the hydrogen-dissolved water generating method used in the hydrogen-dissolved water generating device of FIG. 1; [FIG. 4] is a flowchart showing the processing procedure of a modification of the hydrogen-dissolved water generating method of FIG. 3; [FIG. 5] is a flowchart showing the processing procedure of another modification of the hydrogen-dissolved water generating method of FIG. 4; [Fig. 6] is a flowchart showing a processing procedure of still another modification of the hydrogen-dissolved water production method of Fig. 4.
1:透析判定裝置 1: Dialysis judging device
100:透析系統 100: Dialysis system
11:採集部 11: Collection Department
12:檢測部 12: Inspection Department
13:控制部 13: Control Department
14:通知部 14: Notification Department
2:反滲透膜處理裝置 2: Reverse osmosis membrane treatment device
21:軟水化處理裝置 21: Softening treatment device
22:活性碳處理裝置 22: Activated carbon treatment device
23:反滲透膜模塊 23: Reverse osmosis membrane module
3:氫水生成部 3: Hydrogen water generation department
5:透析液製備裝置 5: Dialysate preparation device
6:透析裝置 6: Dialysis device
61:透析液供給裝置 61: Dialysate supply device
62:透析器 62: Dialyzer
62a:透析膜 62a: dialysis membrane
63、64:血液回路 63, 64: blood circuit
65:泵 65: pump
H:患者 H: Patient
Claims (9)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2019061116A JP7011619B2 (en) | 2019-03-27 | 2019-03-27 | Dissolved hydrogen water generator and dissolved hydrogen water generation method |
JP2019-061116 | 2019-03-27 |
Publications (2)
Publication Number | Publication Date |
---|---|
TW202108190A true TW202108190A (en) | 2021-03-01 |
TWI821544B TWI821544B (en) | 2023-11-11 |
Family
ID=72611846
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TW109108996A TWI821544B (en) | 2019-03-27 | 2020-03-18 | Hydrogen-dissolved water generating device and hydrogen-dissolved water generating method |
Country Status (4)
Country | Link |
---|---|
JP (1) | JP7011619B2 (en) |
CN (1) | CN113412128B (en) |
TW (1) | TWI821544B (en) |
WO (1) | WO2020195480A1 (en) |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2012088201A (en) | 2010-10-20 | 2012-05-10 | Japan Health Science Foundation | Device and method for measuring active oxygen amount |
KR20140129291A (en) * | 2012-07-06 | 2014-11-06 | 가부시키가이샤니혼트림 | Device for producing water for preparing dialysate |
JP5714060B2 (en) * | 2013-06-24 | 2015-05-07 | 株式会社日本トリム | Dialysate preparation water production equipment |
JP5901665B2 (en) * | 2014-01-27 | 2016-04-13 | 株式会社日本トリム | Dialysate preparation water production equipment |
JP2015177911A (en) | 2014-03-19 | 2015-10-08 | 株式会社日本トリム | Manufacturing apparatus of dialysate |
JP5840248B2 (en) * | 2014-03-19 | 2016-01-06 | 株式会社日本トリム | Dialysate production equipment |
JP2016077675A (en) * | 2014-10-20 | 2016-05-16 | 株式会社日本トリム | Peritoneal dialysis fluid manufacturing device |
DE102015012519A1 (en) * | 2015-09-26 | 2017-03-30 | Fresenius Medical Care Deutschland Gmbh | Determination in blood of dissolved gases in the extracorporeal circulation |
JP2017087168A (en) * | 2015-11-13 | 2017-05-25 | シャープ株式会社 | Hydrogen-containing water production device, and hydrogen-containing water production method |
CN109475674B (en) * | 2016-07-27 | 2021-01-15 | 日本多宁股份有限公司 | Method for cleaning dialysate production device |
-
2019
- 2019-03-27 JP JP2019061116A patent/JP7011619B2/en active Active
-
2020
- 2020-02-26 WO PCT/JP2020/007729 patent/WO2020195480A1/en active Application Filing
- 2020-02-26 CN CN202080013254.0A patent/CN113412128B/en active Active
- 2020-03-18 TW TW109108996A patent/TWI821544B/en active
Also Published As
Publication number | Publication date |
---|---|
JP7011619B2 (en) | 2022-01-26 |
TWI821544B (en) | 2023-11-11 |
CN113412128A (en) | 2021-09-17 |
CN113412128B (en) | 2024-08-06 |
WO2020195480A1 (en) | 2020-10-01 |
JP2020156884A (en) | 2020-10-01 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JP5901665B2 (en) | Dialysate preparation water production equipment | |
TW202033456A (en) | Hydrogenation method and hydrogenation device | |
WO2014006740A1 (en) | Device for producing water for preparing dialysate | |
JP2000350989A (en) | Production of medical treatment water | |
JP5714060B2 (en) | Dialysate preparation water production equipment | |
JP6836914B2 (en) | Water treatment equipment, dialysate preparation water production equipment and hydrogen water server | |
JP5840248B2 (en) | Dialysate production equipment | |
TW202033266A (en) | Hydrogenation device and method for determining a degree of consumption of a hydrogen-permeable membrane | |
JP5940689B1 (en) | Dialysate preparation water production equipment | |
TWI833931B (en) | Hydrogen-dissolved water generating device and hydrogen-dissolved water generating method | |
JP2015177911A (en) | Manufacturing apparatus of dialysate | |
TWI821544B (en) | Hydrogen-dissolved water generating device and hydrogen-dissolved water generating method | |
JP5940753B1 (en) | Equipment for producing hydrogen-containing peritoneal dialysis fluid | |
CN109475674B (en) | Method for cleaning dialysate production device | |
JP6479140B2 (en) | Cleaning method for dialysate production equipment | |
TW202100231A (en) | Hydrogenation device and method for determining degree of consumption of hydrogen-permeable membrane | |
JP7514191B2 (en) | Water treatment device and water treatment method | |
JP6276790B2 (en) | Electrolyzed water generating device, dialysate preparation water manufacturing apparatus using the same, and electrolyzed water generating method | |
TWI427189B (en) | Method and apparatus for producing high concentration hypochlorochloride sterilized water | |
JP7385616B2 (en) | Electrolyzed water generator |