TWI818168B - 治療眼疾的方法 - Google Patents

治療眼疾的方法 Download PDF

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Publication number
TWI818168B
TWI818168B TW109111356A TW109111356A TWI818168B TW I818168 B TWI818168 B TW I818168B TW 109111356 A TW109111356 A TW 109111356A TW 109111356 A TW109111356 A TW 109111356A TW I818168 B TWI818168 B TW I818168B
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TW
Taiwan
Prior art keywords
eye
diabetic retinopathy
beauvericin
administration
day
Prior art date
Application number
TW109111356A
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English (en)
Chinese (zh)
Other versions
TW202102252A (zh
Inventor
李水盛
蘇銘嘉
林隆誌
徐兆民
Original Assignee
資元堂生物科技股份有限公司
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Publication of TW202102252A publication Critical patent/TW202102252A/zh
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Publication of TWI818168B publication Critical patent/TWI818168B/zh

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/15Depsipeptides; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
TW109111356A 2019-04-03 2020-04-01 治療眼疾的方法 TWI818168B (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201962828616P 2019-04-03 2019-04-03
US62/828,616 2019-04-03
US201962899279P 2019-09-12 2019-09-12
US62/899,279 2019-09-12

Publications (2)

Publication Number Publication Date
TW202102252A TW202102252A (zh) 2021-01-16
TWI818168B true TWI818168B (zh) 2023-10-11

Family

ID=72662774

Family Applications (1)

Application Number Title Priority Date Filing Date
TW109111356A TWI818168B (zh) 2019-04-03 2020-04-01 治療眼疾的方法

Country Status (8)

Country Link
US (1) US11033603B2 (https=)
EP (1) EP3946414B1 (https=)
JP (1) JP7461663B2 (https=)
KR (1) KR20210149087A (https=)
CN (1) CN113795268B (https=)
SG (1) SG11202110659SA (https=)
TW (1) TWI818168B (https=)
WO (1) WO2020200241A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI788083B (zh) * 2021-11-03 2022-12-21 葡萄王生技股份有限公司 蟬花菌絲體活性物質用於治療黃斑部病變之用途
CN120936366A (zh) * 2023-03-20 2025-11-11 资元堂生物科技股份有限公司 一种白殭菌素用于制备抑制血管新生药物的用途

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140371158A1 (en) * 2013-06-14 2014-12-18 Georgia Regents University Beauvericin compositions and methods thereof for inhibiting the hsp90 chaperone pathway

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0327316A (ja) * 1989-06-23 1991-02-05 Kitasato Inst:The 高脂血症治療剤
KR20080031474A (ko) * 2005-07-27 2008-04-08 유니버시티 오브 플로리다 리서치 파운데이션, 아이엔씨. 안구 질환의 치료를 위한 열충격의 사용
CN101669939A (zh) * 2009-09-22 2010-03-17 中山大学 恩镰孢菌素类化合物在制备抗耐药结核菌药物中的应用
US20140275091A1 (en) * 2013-03-15 2014-09-18 Coyote Pharmaceuticals, Inc. Ocular formulations comprising geranylgeranylacetone derivatives for intraocular delivery
CN109200066A (zh) * 2017-07-07 2019-01-15 葡萄王生技股份有限公司 蝉花活性物质及其用于预防、延缓或治疗白内障的用途

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140371158A1 (en) * 2013-06-14 2014-12-18 Georgia Regents University Beauvericin compositions and methods thereof for inhibiting the hsp90 chaperone pathway

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
期刊 José Norberto Vásquez-Bonilla et al., "Biological activity of mycotoxin beauvericin in cancer cells", Rev Mex Cienc Farm, 48(4), 2017, 17-27. *

Also Published As

Publication number Publication date
EP3946414A4 (en) 2022-12-07
US20200316165A1 (en) 2020-10-08
JP7461663B2 (ja) 2024-04-04
KR20210149087A (ko) 2021-12-08
JP2022528566A (ja) 2022-06-14
CN113795268B (zh) 2025-04-08
WO2020200241A1 (en) 2020-10-08
TW202102252A (zh) 2021-01-16
EP3946414A1 (en) 2022-02-09
EP3946414B1 (en) 2025-12-03
CA3132137A1 (en) 2020-10-08
EP3946414C0 (en) 2025-12-03
CN113795268A (zh) 2021-12-14
US11033603B2 (en) 2021-06-15
SG11202110659SA (en) 2021-10-28

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