TWI807804B - 高透氧矽水膠組成物、使用高透氧矽水膠組成物製作的隱形眼鏡及其製作方法 - Google Patents
高透氧矽水膠組成物、使用高透氧矽水膠組成物製作的隱形眼鏡及其製作方法 Download PDFInfo
- Publication number
- TWI807804B TWI807804B TW111116293A TW111116293A TWI807804B TW I807804 B TWI807804 B TW I807804B TW 111116293 A TW111116293 A TW 111116293A TW 111116293 A TW111116293 A TW 111116293A TW I807804 B TWI807804 B TW I807804B
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- Prior art keywords
- hydrogel composition
- silicone hydrogel
- contact lens
- oxygen
- high oxygen
- Prior art date
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- 239000000017 hydrogel Substances 0.000 title claims abstract description 58
- 229920001296 polysiloxane Polymers 0.000 title claims abstract description 51
- 239000001301 oxygen Substances 0.000 title claims abstract description 25
- 229910052760 oxygen Inorganic materials 0.000 title claims abstract description 25
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 title claims abstract description 21
- 230000035699 permeability Effects 0.000 title claims abstract description 18
- 238000004519 manufacturing process Methods 0.000 title abstract description 13
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 claims abstract description 46
- 229910052710 silicon Inorganic materials 0.000 claims abstract description 46
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- AMQJEAYHLZJPGS-UHFFFAOYSA-N N-Pentanol Chemical compound CCCCCO AMQJEAYHLZJPGS-UHFFFAOYSA-N 0.000 claims description 6
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- CYIGRWUIQAVBFG-UHFFFAOYSA-N 1,2-bis(2-ethenoxyethoxy)ethane Chemical compound C=COCCOCCOCCOC=C CYIGRWUIQAVBFG-UHFFFAOYSA-N 0.000 claims description 5
- SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 claims description 5
- NIXOWILDQLNWCW-UHFFFAOYSA-N 2-Propenoic acid Natural products OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims description 5
- CERQOIWHTDAKMF-UHFFFAOYSA-N Methacrylic acid Chemical compound CC(=C)C(O)=O CERQOIWHTDAKMF-UHFFFAOYSA-N 0.000 claims description 5
- KYIKRXIYLAGAKQ-UHFFFAOYSA-N abcn Chemical compound C1CCCCC1(C#N)N=NC1(C#N)CCCCC1 KYIKRXIYLAGAKQ-UHFFFAOYSA-N 0.000 claims description 5
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- KOMNUTZXSVSERR-UHFFFAOYSA-N 1,3,5-tris(prop-2-enyl)-1,3,5-triazinane-2,4,6-trione Chemical compound C=CCN1C(=O)N(CC=C)C(=O)N(CC=C)C1=O KOMNUTZXSVSERR-UHFFFAOYSA-N 0.000 claims description 4
- ZSZRUEAFVQITHH-UHFFFAOYSA-N 2-(2-methylprop-2-enoyloxy)ethyl 2-(trimethylazaniumyl)ethyl phosphate Chemical compound CC(=C)C(=O)OCCOP([O-])(=O)OCC[N+](C)(C)C ZSZRUEAFVQITHH-UHFFFAOYSA-N 0.000 claims description 4
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- QRIMLDXJAPZHJE-UHFFFAOYSA-N 2,3-dihydroxypropyl 2-methylprop-2-enoate Chemical compound CC(=C)C(=O)OCC(O)CO QRIMLDXJAPZHJE-UHFFFAOYSA-N 0.000 claims description 3
- MSXVEPNJUHWQHW-UHFFFAOYSA-N 2-methylbutan-2-ol Chemical compound CCC(C)(C)O MSXVEPNJUHWQHW-UHFFFAOYSA-N 0.000 claims description 3
- OHLUUHNLEMFGTQ-UHFFFAOYSA-N N-methylacetamide Chemical compound CNC(C)=O OHLUUHNLEMFGTQ-UHFFFAOYSA-N 0.000 claims description 3
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- PNLUGRYDUHRLOF-UHFFFAOYSA-N n-ethenyl-n-methylacetamide Chemical compound C=CN(C)C(C)=O PNLUGRYDUHRLOF-UHFFFAOYSA-N 0.000 claims description 2
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- 238000005406 washing Methods 0.000 claims 2
- PUPZLCDOIYMWBV-UHFFFAOYSA-N (+/-)-1,3-Butanediol Chemical compound CC(O)CCO PUPZLCDOIYMWBV-UHFFFAOYSA-N 0.000 claims 1
- CDDDRVNOHLVEED-UHFFFAOYSA-N 1-cyclohexyl-3-[1-[[1-(cyclohexylcarbamoylamino)cyclohexyl]diazenyl]cyclohexyl]urea Chemical compound C1CCCCC1(N=NC1(CCCCC1)NC(=O)NC1CCCCC1)NC(=O)NC1CCCCC1 CDDDRVNOHLVEED-UHFFFAOYSA-N 0.000 claims 1
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- 108050008265 La-related protein 6 Proteins 0.000 claims 1
- ZBGFFOJGTVCHFT-UHFFFAOYSA-N N,N-dimethylprop-2-enamide Chemical compound CN(C(C=C)=O)C.CN(C(C=C)=O)C ZBGFFOJGTVCHFT-UHFFFAOYSA-N 0.000 claims 1
- VBWIZSYFQSOUFQ-UHFFFAOYSA-N cyclohexanecarbonitrile Chemical compound N#CC1CCCCC1 VBWIZSYFQSOUFQ-UHFFFAOYSA-N 0.000 claims 1
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- 238000001029 thermal curing Methods 0.000 description 3
- QNODIIQQMGDSEF-UHFFFAOYSA-N (1-hydroxycyclohexyl)-phenylmethanone Chemical compound C=1C=CC=CC=1C(=O)C1(O)CCCCC1 QNODIIQQMGDSEF-UHFFFAOYSA-N 0.000 description 2
- RIWRBSMFKVOJMN-UHFFFAOYSA-N 2-methyl-1-phenylpropan-2-ol Chemical compound CC(C)(O)CC1=CC=CC=C1 RIWRBSMFKVOJMN-UHFFFAOYSA-N 0.000 description 2
- XOJWAAUYNWGQAU-UHFFFAOYSA-N 4-(2-methylprop-2-enoyloxy)butyl 2-methylprop-2-enoate Chemical compound CC(=C)C(=O)OCCCCOC(=O)C(C)=C XOJWAAUYNWGQAU-UHFFFAOYSA-N 0.000 description 2
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- HWSSEYVMGDIFMH-UHFFFAOYSA-N 2-[2-[2-(2-methylprop-2-enoyloxy)ethoxy]ethoxy]ethyl 2-methylprop-2-enoate Chemical compound CC(=C)C(=O)OCCOCCOCCOC(=O)C(C)=C HWSSEYVMGDIFMH-UHFFFAOYSA-N 0.000 description 1
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- 239000004971 Cross linker Substances 0.000 description 1
- MBJXYAMXWSRFKC-UHFFFAOYSA-N N-[3-tris(trimethylsilyloxy)silylpropyl]penta-2,4-dienamide Chemical compound C(=C)C=CC(=O)NCCC[Si](O[Si](C)(C)C)(O[Si](C)(C)C)O[Si](C)(C)C MBJXYAMXWSRFKC-UHFFFAOYSA-N 0.000 description 1
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- NBOCBWJUDBATAS-UHFFFAOYSA-N [2-hydroxy-3-[3-[methyl-bis(trimethylsilyloxy)silyl]propoxy]propyl] 2-methylprop-2-enoate Chemical compound CC(=C)C(=O)OCC(O)COCCC[Si](C)(O[Si](C)(C)C)O[Si](C)(C)C NBOCBWJUDBATAS-UHFFFAOYSA-N 0.000 description 1
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- XAASNKQYFKTYTR-UHFFFAOYSA-N tris(trimethylsilyloxy)silicon Chemical compound C[Si](C)(C)O[Si](O[Si](C)(C)C)O[Si](C)(C)C XAASNKQYFKTYTR-UHFFFAOYSA-N 0.000 description 1
- 238000009281 ultraviolet germicidal irradiation Methods 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L83/00—Compositions of macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon only; Compositions of derivatives of such polymers
- C08L83/10—Block- or graft-copolymers containing polysiloxane sequences
- C08L83/12—Block- or graft-copolymers containing polysiloxane sequences containing polyether sequences
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F283/00—Macromolecular compounds obtained by polymerising monomers on to polymers provided for in subclass C08G
- C08F283/12—Macromolecular compounds obtained by polymerising monomers on to polymers provided for in subclass C08G on to polysiloxanes
- C08F283/124—Macromolecular compounds obtained by polymerising monomers on to polymers provided for in subclass C08G on to polysiloxanes on to polysiloxanes having carbon-to-carbon double bonds
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F290/00—Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups
- C08F290/02—Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups on to polymers modified by introduction of unsaturated end groups
- C08F290/06—Polymers provided for in subclass C08G
- C08F290/068—Polysiloxanes
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L51/00—Compositions of graft polymers in which the grafted component is obtained by reactions only involving carbon-to-carbon unsaturated bonds; Compositions of derivatives of such polymers
- C08L51/08—Compositions of graft polymers in which the grafted component is obtained by reactions only involving carbon-to-carbon unsaturated bonds; Compositions of derivatives of such polymers grafted on to macromolecular compounds obtained otherwise than by reactions only involving unsaturated carbon-to-carbon bonds
- C08L51/085—Compositions of graft polymers in which the grafted component is obtained by reactions only involving carbon-to-carbon unsaturated bonds; Compositions of derivatives of such polymers grafted on to macromolecular compounds obtained otherwise than by reactions only involving unsaturated carbon-to-carbon bonds on to polysiloxanes
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B1/00—Optical elements characterised by the material of which they are made; Optical coatings for optical elements
- G02B1/04—Optical elements characterised by the material of which they are made; Optical coatings for optical elements made of organic materials, e.g. plastics
- G02B1/041—Lenses
- G02B1/043—Contact lenses
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G77/00—Macromolecular compounds obtained by reactions forming a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon in the main chain of the macromolecule
- C08G77/42—Block-or graft-polymers containing polysiloxane sequences
- C08G77/46—Block-or graft-polymers containing polysiloxane sequences containing polyether sequences
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- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Eyeglasses (AREA)
- Macromonomer-Based Addition Polymer (AREA)
- Compositions Of Macromolecular Compounds (AREA)
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| TW111116293A TWI807804B (zh) | 2022-04-28 | 2022-04-28 | 高透氧矽水膠組成物、使用高透氧矽水膠組成物製作的隱形眼鏡及其製作方法 |
| EP23166668.6A EP4269458B1 (en) | 2022-04-28 | 2023-04-05 | High oxygen permeability silicone hydrogel composition, contact lens made from high oxygen permeability silicone hydrogel composition and manufacturing method thereof |
| JP2023070837A JP7446025B2 (ja) | 2022-04-28 | 2023-04-24 | 高酸素透過性シリコーンハイドロゲル組成物、高酸素透過性シリコーンハイドロゲル組成物から製造されたコンタクトレンズ及びその製造方法 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| TW111116293A TWI807804B (zh) | 2022-04-28 | 2022-04-28 | 高透氧矽水膠組成物、使用高透氧矽水膠組成物製作的隱形眼鏡及其製作方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TWI807804B true TWI807804B (zh) | 2023-07-01 |
| TW202342646A TW202342646A (zh) | 2023-11-01 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW111116293A TWI807804B (zh) | 2022-04-28 | 2022-04-28 | 高透氧矽水膠組成物、使用高透氧矽水膠組成物製作的隱形眼鏡及其製作方法 |
Country Status (3)
| Country | Link |
|---|---|
| EP (1) | EP4269458B1 (enExample) |
| JP (1) | JP7446025B2 (enExample) |
| TW (1) | TWI807804B (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN118638279B (zh) * | 2024-08-14 | 2024-12-03 | 吉林爱惠瞳医用科技有限公司 | 一种高透氧硅水凝胶材料及其制备方法和应用 |
| CN119638919B (zh) * | 2024-12-13 | 2025-11-28 | 江苏丽雯光学有限公司 | 一种高透氧硅水凝胶隐形眼镜及其制备方法 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW201502172A (zh) * | 2013-07-02 | 2015-01-16 | Hoya Corp | 製造具親水性表面之含聚矽氧之共聚物成形品之方法及具親水性表面之聚矽氧水凝膠隱形眼鏡 |
| TWI477560B (zh) * | 2013-02-07 | 2015-03-21 | Benq Materials Corp | 隱形眼鏡材料、隱形眼鏡的製造方法與由此方法所製造出之隱形眼鏡 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3572144B2 (ja) * | 1996-05-31 | 2004-09-29 | 名糖産業株式会社 | デキストランエステル共重合体 |
| JP2018193492A (ja) * | 2017-05-18 | 2018-12-06 | 信越化学工業株式会社 | 重合性基含有オルガノポリシロキサンの製造方法 |
| US20210017383A1 (en) * | 2019-07-19 | 2021-01-21 | Mcmaster University | Silicone co-polymers and methods of use thereof to modify silicone elastomers |
| CN112898506B (zh) * | 2020-12-31 | 2023-03-24 | 江苏海伦隐形眼镜有限公司 | 一种高透氧性硅水凝胶及角膜接触镜 |
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2022
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2023
- 2023-04-05 EP EP23166668.6A patent/EP4269458B1/en active Active
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| Publication number | Priority date | Publication date | Assignee | Title |
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| TWI477560B (zh) * | 2013-02-07 | 2015-03-21 | Benq Materials Corp | 隱形眼鏡材料、隱形眼鏡的製造方法與由此方法所製造出之隱形眼鏡 |
| TW201502172A (zh) * | 2013-07-02 | 2015-01-16 | Hoya Corp | 製造具親水性表面之含聚矽氧之共聚物成形品之方法及具親水性表面之聚矽氧水凝膠隱形眼鏡 |
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| TW202342646A (zh) | 2023-11-01 |
| EP4269458C0 (en) | 2024-09-11 |
| JP7446025B2 (ja) | 2024-03-08 |
| EP4269458A1 (en) | 2023-11-01 |
| EP4269458B1 (en) | 2024-09-11 |
| JP2023164345A (ja) | 2023-11-10 |
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