TWI754225B - 治療低血壓之方法 - Google Patents

治療低血壓之方法 Download PDF

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Publication number
TWI754225B
TWI754225B TW109105582A TW109105582A TWI754225B TW I754225 B TWI754225 B TW I754225B TW 109105582 A TW109105582 A TW 109105582A TW 109105582 A TW109105582 A TW 109105582A TW I754225 B TWI754225 B TW I754225B
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TW
Taiwan
Prior art keywords
angiotensin
patient
blood pressure
arterial blood
mean arterial
Prior art date
Application number
TW109105582A
Other languages
English (en)
Chinese (zh)
Other versions
TW202038927A (zh
Inventor
喬治 堤馬許
拉克摩爾 齊瓦拉
Original Assignee
美商拉荷亞製藥公司
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Publication date
Application filed by 美商拉荷亞製藥公司 filed Critical 美商拉荷亞製藥公司
Publication of TW202038927A publication Critical patent/TW202038927A/zh
Application granted granted Critical
Publication of TWI754225B publication Critical patent/TWI754225B/zh

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A61K38/085—Angiotensins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Emergency Medicine (AREA)
  • Vascular Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
TW109105582A 2014-07-08 2015-07-08 治療低血壓之方法 TWI754225B (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462022054P 2014-07-08 2014-07-08
US62/022,054 2014-07-08

Publications (2)

Publication Number Publication Date
TW202038927A TW202038927A (zh) 2020-11-01
TWI754225B true TWI754225B (zh) 2022-02-01

Family

ID=55064810

Family Applications (3)

Application Number Title Priority Date Filing Date
TW109105582A TWI754225B (zh) 2014-07-08 2015-07-08 治療低血壓之方法
TW104122255A TWI688385B (zh) 2014-07-08 2015-07-08 治療低血壓之方法
TW110149288A TW202214219A (zh) 2014-07-08 2015-07-08 治療低血壓之方法

Family Applications After (2)

Application Number Title Priority Date Filing Date
TW104122255A TWI688385B (zh) 2014-07-08 2015-07-08 治療低血壓之方法
TW110149288A TW202214219A (zh) 2014-07-08 2015-07-08 治療低血壓之方法

Country Status (14)

Country Link
US (3) US20160074465A1 (en:Method)
EP (2) EP3381465A1 (en:Method)
JP (2) JP2017519799A (en:Method)
KR (1) KR20170026486A (en:Method)
CN (1) CN106794224A (en:Method)
AU (2) AU2015287955A1 (en:Method)
BR (1) BR112017000303A2 (en:Method)
CA (1) CA2954016A1 (en:Method)
EA (2) EA036514B1 (en:Method)
IL (1) IL249936A0 (en:Method)
MX (1) MX2017000306A (en:Method)
SG (2) SG11201610897VA (en:Method)
TW (3) TWI754225B (en:Method)
WO (1) WO2016007589A1 (en:Method)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9572856B2 (en) 2009-12-16 2017-02-21 The George Washington University a Congressionally Chartered Not-for-Profit Corporation Method of treating low blood pressure
WO2015095535A1 (en) 2013-12-18 2015-06-25 The George Washington University, A Congressional Chartered Not-For-Profit Corporation Angiotensin ii alone or in combination for the treatment of hypotension
US9925233B2 (en) 2015-01-30 2018-03-27 Par Pharmaceutical, Inc. Vasopressin formulations for use in treatment of hypotension
CA3010781A1 (en) 2016-01-07 2017-07-13 La Jolla Pharmaceutical Company Methods for administering angiotensin ii
WO2018191678A1 (en) * 2017-04-14 2018-10-18 La Jolla Pharmaceutical Company Methods for administering angiotensin ii
TW201927331A (zh) * 2017-12-15 2019-07-16 美商拉荷亞製藥公司 血管收縮素組合物及與其相關之方法
US10653646B2 (en) 2018-03-23 2020-05-19 Nevakar Inc. Epinephrine compositions and containers
KR102258546B1 (ko) 2018-10-26 2021-06-01 양성심 유기농 케일을 주 성분으로 하는 건강기능식품 조성물

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7115266B2 (en) 2001-10-05 2006-10-03 Cytos Biotechnology Ag Angiotensin peptide-carrier conjugates and uses thereof
DE602006021600D1 (de) * 2005-09-29 2011-06-09 Fibrogen Inc Verfahren zur senkung des blutdrucks
CA2742791A1 (en) * 2008-11-28 2010-06-03 Abbott Laboratories Stable antibody compositions and methods for stabilizing same
US9572856B2 (en) * 2009-12-16 2017-02-21 The George Washington University a Congressionally Chartered Not-for-Profit Corporation Method of treating low blood pressure
WO2015095535A1 (en) * 2013-12-18 2015-06-25 The George Washington University, A Congressional Chartered Not-For-Profit Corporation Angiotensin ii alone or in combination for the treatment of hypotension

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
LW Busse et al., Angiotensin II may be useful for the treatment of hypotension in distributive shock, but a safe and efficacious dose is unknown, Crit Care.,vol.18, 20140317, pp.S57; *
Yunge M et al., Angiotensin for septic shock unresponsive to noradrenaline,Arch Dis Child., vol.82, 2000, pp.388-389 *

Also Published As

Publication number Publication date
SG10201804034QA (en) 2018-07-30
US20160074465A1 (en) 2016-03-17
CN106794224A (zh) 2017-05-31
WO2016007589A1 (en) 2016-01-14
KR20170026486A (ko) 2017-03-08
US20200237853A1 (en) 2020-07-30
JP2017519799A (ja) 2017-07-20
EP3381465A1 (en) 2018-10-03
TW202214219A (zh) 2022-04-16
EA201692534A1 (ru) 2017-06-30
TWI688385B (zh) 2020-03-21
US20180311306A1 (en) 2018-11-01
TW201625231A (zh) 2016-07-16
JP2020143139A (ja) 2020-09-10
EP3007722A4 (en) 2016-05-25
IL249936A0 (en) 2017-03-30
EA202091873A2 (ru) 2020-11-30
CA2954016A1 (en) 2016-01-14
AU2021201669A1 (en) 2021-04-08
EA036514B1 (ru) 2020-11-18
AU2015287955A1 (en) 2017-02-02
EA202091873A3 (ru) 2021-01-29
SG11201610897VA (en) 2017-01-27
BR112017000303A2 (pt) 2017-11-07
EP3007722A1 (en) 2016-04-20
MX2017000306A (es) 2017-07-10
TW202038927A (zh) 2020-11-01

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