TWI737285B - 二胺基嘧啶類化合物治療子宮內膜異位相關的疼痛的方法 - Google Patents
二胺基嘧啶類化合物治療子宮內膜異位相關的疼痛的方法 Download PDFInfo
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- TWI737285B TWI737285B TW109114698A TW109114698A TWI737285B TW I737285 B TWI737285 B TW I737285B TW 109114698 A TW109114698 A TW 109114698A TW 109114698 A TW109114698 A TW 109114698A TW I737285 B TWI737285 B TW I737285B
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- CAWZRIXWFRFUQB-IOSLPCCCSA-N α,β Methylene ATP Chemical compound C1=NC=2C(N)=NC=NC=2N1[C@@H]1O[C@H](COP(O)(=O)CP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O CAWZRIXWFRFUQB-IOSLPCCCSA-N 0.000 description 1
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
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- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| WOPCT/CN2019/085209 | 2019-04-30 | ||
| CN2019085209 | 2019-04-30 |
Publications (2)
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| TW202106303A TW202106303A (zh) | 2021-02-16 |
| TWI737285B true TWI737285B (zh) | 2021-08-21 |
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| TW109114698A TWI737285B (zh) | 2019-04-30 | 2020-04-30 | 二胺基嘧啶類化合物治療子宮內膜異位相關的疼痛的方法 |
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| JP (1) | JP7663508B2 (enExample) |
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| SG (1) | SG11202111960PA (enExample) |
| TW (1) | TWI737285B (enExample) |
| WO (1) | WO2020221277A1 (enExample) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN117186068A (zh) * | 2017-11-01 | 2023-12-08 | 北京泰德制药股份有限公司 | P2x3和/或p2x2/3受体拮抗剂、包含其的药物组合物及其用途 |
| WO2023081800A1 (en) * | 2021-11-05 | 2023-05-11 | The Regents Of The University Of California | Alpha-2a adrenergic receptor modulators and uses thereof |
Citations (2)
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|---|---|---|---|---|
| CN108779119A (zh) * | 2016-03-25 | 2018-11-09 | 传入制药公司 | 嘧啶及其变体、及其用途 |
| CN108834412A (zh) * | 2016-03-14 | 2018-11-16 | 传入制药公司 | 嘧啶及其变体、及其用途 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008104474A1 (en) * | 2007-02-28 | 2008-09-04 | F. Hoffmann-La Roche Ag | Diaminopyrimidines |
| CN117186068A (zh) * | 2017-11-01 | 2023-12-08 | 北京泰德制药股份有限公司 | P2x3和/或p2x2/3受体拮抗剂、包含其的药物组合物及其用途 |
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2020
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- 2020-04-29 WO PCT/CN2020/087689 patent/WO2020221277A1/zh not_active Ceased
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- 2020-04-29 US US17/607,475 patent/US12605381B2/en active Active
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- 2020-04-29 CA CA3138238A patent/CA3138238A1/en active Pending
- 2020-04-29 SG SG11202111960PA patent/SG11202111960PA/en unknown
- 2020-04-30 TW TW109114698A patent/TWI737285B/zh active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108834412A (zh) * | 2016-03-14 | 2018-11-16 | 传入制药公司 | 嘧啶及其变体、及其用途 |
| CN108779119A (zh) * | 2016-03-25 | 2018-11-09 | 传入制药公司 | 嘧啶及其变体、及其用途 |
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| WO2020221277A1 (zh) | 2020-11-05 |
| KR102935431B1 (ko) | 2026-03-05 |
| JP7663508B2 (ja) | 2025-04-16 |
| MX2021013347A (es) | 2022-01-24 |
| CN114007620A (zh) | 2022-02-01 |
| CA3138238A1 (en) | 2020-11-05 |
| AU2020266947B2 (en) | 2025-10-09 |
| SG11202111960PA (en) | 2021-12-30 |
| BR112021021838A8 (pt) | 2023-02-28 |
| BR112021021838A2 (pt) | 2022-01-04 |
| US12605381B2 (en) | 2026-04-21 |
| JP2022531570A (ja) | 2022-07-07 |
| AU2020266947A1 (en) | 2021-12-16 |
| KR20220008286A (ko) | 2022-01-20 |
| EP3960178A1 (en) | 2022-03-02 |
| US20220249478A1 (en) | 2022-08-11 |
| TW202106303A (zh) | 2021-02-16 |
| CN114007620B (zh) | 2024-08-06 |
| EP3960178B1 (en) | 2026-03-18 |
| EP3960178A4 (en) | 2023-01-25 |
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