TWI736243B - 二胺基嘧啶類化合物治療咳嗽的方法 - Google Patents
二胺基嘧啶類化合物治療咳嗽的方法 Download PDFInfo
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- TWI736243B TWI736243B TW109114696A TW109114696A TWI736243B TW I736243 B TWI736243 B TW I736243B TW 109114696 A TW109114696 A TW 109114696A TW 109114696 A TW109114696 A TW 109114696A TW I736243 B TWI736243 B TW I736243B
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- 206010011224 Cough Diseases 0.000 title claims abstract description 80
- 238000000034 method Methods 0.000 title abstract description 17
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- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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| CN1930135B (zh) * | 2004-03-05 | 2011-12-28 | 弗·哈夫曼-拉罗切有限公司 | 作为p2x3和p2x2/3拮抗剂的二氨基嘧啶 |
| CA2619919C (en) * | 2005-09-01 | 2014-04-01 | F. Hoffmann-La Roche Ag | Diaminopyrimidines as p2x3 and p2x2/3 modulators |
| AU2007304280B2 (en) | 2006-10-04 | 2013-01-31 | F. Hoffmann-La Roche Ag | Process for synthesis of phenoxy diaminopyrimidine derivatives |
| RU2650118C2 (ru) * | 2013-08-23 | 2018-04-09 | Афферент Фармасьютикалз Инк. | Способ лечения острого, хронического и подострого кашля и непреодолимого желания откашляться |
| KR20180054843A (ko) * | 2015-09-29 | 2018-05-24 | 애퍼런트 파마슈티컬스 인크. | 기침 치료에 사용하기 위한 디아미노피리미딘 p2x3 및 p2x2/3 수용체 조정제 |
| MA43821A (fr) * | 2016-03-14 | 2018-11-28 | Afferent Pharmaceuticals Inc | Pyrimidines et variantes de celles-ci, et leurs utilisations |
| JP7207634B2 (ja) | 2017-11-01 | 2023-01-18 | ベイジン タイド ファーマシューティカル カンパニー リミテッド | Ｐ２ｘ３及び／又はｐ２ｘ２／３受容体アンタゴニスト、それを含む医薬組成物及びその使用 |
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- 2020-04-29 JP JP2021564189A patent/JP7665529B2/ja active Active
- 2020-04-29 SG SG11202111877TA patent/SG11202111877TA/en unknown
- 2020-04-29 WO PCT/CN2020/087686 patent/WO2020221274A1/zh not_active Ceased
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- 2020-04-29 BR BR112021021600A patent/BR112021021600A2/pt unknown
- 2020-04-29 US US17/607,438 patent/US20220211703A1/en active Pending
- 2020-04-29 MX MX2021013338A patent/MX2021013338A/es unknown
- 2020-04-29 AU AU2020265327A patent/AU2020265327B2/en active Active
- 2020-04-29 KR KR1020217038551A patent/KR102935436B1/ko active Active
- 2020-04-30 TW TW109114696A patent/TWI736243B/zh active
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108779119A (zh) * | 2016-03-25 | 2018-11-09 | 传入制药公司 | 嘧啶及其变体、及其用途 |
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| Publication number | Publication date |
|---|---|
| JP7665529B2 (ja) | 2025-04-21 |
| EP3960179A4 (en) | 2023-01-25 |
| US20220211703A1 (en) | 2022-07-07 |
| CN114007619A (zh) | 2022-02-01 |
| SG11202111877TA (en) | 2021-11-29 |
| TW202106302A (zh) | 2021-02-16 |
| CA3138780A1 (en) | 2020-11-05 |
| KR102935436B1 (ko) | 2026-03-05 |
| EP3960179A1 (en) | 2022-03-02 |
| BR112021021600A2 (pt) | 2022-01-04 |
| EP3960179B1 (en) | 2026-03-18 |
| CN114007619B (zh) | 2024-08-06 |
| MX2021013338A (es) | 2022-01-24 |
| AU2020265327B2 (en) | 2025-09-11 |
| AU2020265327A1 (en) | 2021-12-16 |
| KR20220007620A (ko) | 2022-01-18 |
| JP2022530890A (ja) | 2022-07-04 |
| WO2020221274A1 (zh) | 2020-11-05 |
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