TWI701051B - Makeup cosmetic composition comprising lamellar structure - Google Patents

Abstract

Disclosed is an oil-in-water type makeup cosmetic composition containing an aqueous phase and an oil phase.  The composition comprises inorganic powder surface-treated with a hydrophilic coating agent and dispersed in the aqueous phase, and has a ceramide-containing multilayer lamellar structure.  The makeup cosmetic composition shows excellent formulation stability, and has an excellent skin moisturizing effect when applied to the skin.

Description

Makeup cosmetic composition containing layered structure

The reference of the present invention is Korean Patent KR10-2011-0093634 A.

This specification is about a cosmetic composition in which ceramide is stabilized by using inorganic powder surface-treated with a hydrophilic coating agent.

Ceramide occupies at least 40% of the keratinocyte lipids that form the stratum corneum. It is an essential component for forming the stratum corneum structure or displaying the function of the stratum corneum, and has an excellent moisturizing effect and barrier function enhancement effect. However, when ceramide is incorporated into cosmetic formulations in large amounts, it is slightly soluble and is therefore used after reducing its particle size. In this case, however, the formulation will experience decreased stability and gelation.

When encapsulated ceramide is used to solve this problem, the disadvantage is that a large amount of encapsulating agent will reduce the actual amount of ceramide and the encapsulating agent based on sugar or polymer will make the feeling of use worse.

Particle agglomeration causes gelling of ceramide, which is avoided by increasing the particle size by multilayer lamellar liquid crystals to stabilize the surface energy. Here, when the cosmetic powder is introduced into the generated particles, the particles become undesirably unstable.

The purpose of this specification is to provide a cosmetic composition for cosmetics, which is stabilized while remaining liquid crystal by using a powder that has been surface-treated with silica.

This specification solves a technical problem by providing an oil-in-water cosmetic composition, which includes stable lamellar liquid crystal while avoiding gelation of ceramide.

This specification solves another technical problem by providing an oil-in-water cosmetic composition including an aqueous phase and an oil phase. The composition includes inorganic powder surface-treated with a hydrophilic coating agent and has a ceramide-containing composition. Multi-layered structure.

This specification solves yet another technical problem by providing a method for preparing an oil-in-water cosmetic composition, which includes an inorganic powder surface-treated with a hydrophilic coating agent and a layered form of multilayer ceramide structure.

In a general aspect, an oil-in-water cosmetic cosmetic composition comprising an aqueous phase and an oil phase is provided. The composition includes an inorganic surface-treated with a hydrophilic coating agent and dispersed in the aqueous phase. Powder, and it has a multi-layered structure containing ceramide.

According to a specific embodiment, the hydrophilic coating agent includes one selected from silica and cellulose.

According to another embodiment, the multi-layer structure includes a glucoside surfactant. Particularly, the glucoside surfactant may be at least one selected from the group consisting of behenyl alcohol, arachidyl alcohol, arachidyl glucoside, C14-22 alcohol and C12-20 alkyl glucoside The group formed.

According to still another specific embodiment, the ceramide may be at least one selected from natural ceramide and pseudo-ceramide.

According to still another specific embodiment, the natural ceramide may be at least one selected from ceramide 1, ceramide 2, ceramide 3, ceramide 4, ceramide 5, ceramide 6, Ceramide 7 and Ceramide 8.

According to yet another specific embodiment, the ceramide may be at least one compound selected from the following chemical formulas 1-6:

(Where R is C9-C21 saturated or unsaturated fatty chain)

(Where n is 1 or 2; and each R and R'is a C9-C21 saturated or unsaturated fatty chain)

[Where m and n are the same or different and each represents an integer of 1-3; k and l are the same or different and each represents 1 or 2; j is 0 or 1; R and R'are the same or different and each represents C1-C31 straight Chain or branched saturated or unsaturated alkyl group, which contains or does not contain a hydroxyl group; A ¹ , A ² and A ^{3 are the} same or different and each represents H or any substituent represented by the following structure , Provided that A ¹ , A ² and A ³ cannot simultaneously represent H:

(Wherein each of M, M ¹ and M ² is selected from alkali metal, lysine, arginine, histidine, triethanolamine, amine, polyquaternium-4, poly Quaternium-6, Polyquaternium-7, Polyquaternium-10, Polyquaternium-11, Polyquaternium-16, Lauryldimethylbenzylammonium chloride (lauryldimethylbenzylammonium chloride) And stearyldimethylbenzylammonium chloride (stearyldimethylbenzylammonium chloride), and L is an alkaline earth metal)]

[Where R and R'are the same or different and each represents a C10-C32 linear or branched saturated or unsaturated alkyl group, which contains or does not contain a hydroxyl group; R ³ and R ^{4 are the} same or different and each Represents H or a C1-C4 alkyl group or a hydroxyalkyl group; and R ⁵ is -A or -CH ₂ CH ₂ OA, where A is any substituent represented by the following structure:

(Wherein each of M, M ¹ and M ² is selected from the group consisting of alkaline metal, lysine, arginine, histidine, triethanolamine, amine, polyquaternium-4, polyquaternium -6, polyquaternium-7, polyquaternium-10, polyquaternium-11, polyquaternium-16, dodecyldimethylbenzylammonium chloride and octadecyldimethyl Benzyl ammonium chloride, and L is an alkaline earth metal)]

[Where m and n are the same or different and each represents an integer of 1-4; R and R'are the same or different and each represents a C1-C31 linear or branched saturated or unsaturated alkyl group, which contains or does not contain A hydroxyl group; and A ₁ and A _{2 are the} same or different and each represents H or any substituent represented by the following structure:

(Wherein M, M ¹ and M ² are selected from alkaline metals, lysine, arginine, histidine, triethanolamine, amine, polyquaternium-4, polyquaternium- 6. Polyquaternium-7, Polyquaternium-10, Polyquaternium-11, Polyquaternium-16, Dodecyldimethylbenzylammonium chloride and octadecyldimethyl The group consisting of benzyl ammonium chloride, and L is an alkaline earth metal)]

[Chemical formula 6]

[Where m and n are the same or different and each represents an integer of 1-3; k and l are the same or different and each represents 1 or 2; j is 0 or 1; A ¹ , A ² and A ^{3 are the} same or different and each represents H or any substituent represented by the following structure:

(Wherein each of M, M ¹ and M ² is an alkaline metal or nitrogen-containing organic base, and L is an alkaline earth metal); R is a substituent with the following structure:

(B is the methyl group at 5-, 7- or 8-position of tocopherol, m is an integer of 1-3, and D is -CH ₂ (CH ₃ )-CH- or -CH(CH ₃ )=C -)].

According to still another embodiment, the inorganic powder surface-treated with a hydrophilic coating agent includes at least one selected from titanium dioxide surface-treated with a hydrophilic coating agent and surface treated with a hydrophilic coating agent Treated iron oxide.

According to yet another specific embodiment, the inorganic powder surface-treated with a hydrophilic coating agent is used in an amount of 0.01-25 wt% based on the total weight of the composition.

According to yet another specific embodiment, the ceramide is used in an amount of 0.01-20 wt% based on the total weight of the composition.

According to yet another specific embodiment, the layered structure has a size of 2 μm-30 μm.

In another general aspect, a method for preparing an oil-in-water cosmetic cosmetic composition is provided, which includes the following steps: preparing an oil phase including ceramide and glucoside surfactant; making an aqueous phase Mixing with the inorganic powder surface-treated with a hydrophilic coating agent to disperse the powder; mixing the prepared oil phase with the water phase to form a mixture; and placing the mixture at 45°C-60°C.

In still another general aspect, a method for preparing an oil-in-water cosmetic cosmetic composition is provided, which includes the following steps: preparing an oil phase including ceramide and glucoside surfactant; preparing a water Phase; mixing the prepared oil phase with the water phase to form a mixture; placing the mixture at 45°C-60°C; and mixing the mixture with the inorganic powder surface-treated with a hydrophilic coating agent for dispersion The powder.

The cosmetic composition for cosmetics in one aspect of this specification has excellent formulation stability.

The cosmetic composition of one aspect of this specification includes an inorganic powder and also a stable ceramide lamellar liquid crystal.

The cosmetic composition of one aspect of this specification shows an excellent moisturizing effect when applied to the skin.

The cosmetic composition of one aspect of this specification shows the effect of restoring the barrier function when applied to the skin.

The cosmetic composition of one aspect of this specification shows an excellent effect of improving dry skin when applied to the skin.

Best embodiment

Exemplary specific embodiments will now be described more fully below in order to fully convey the scope of this specification to those skilled in the art.

According to one aspect, there is provided an oil-in-water cosmetic cosmetic composition comprising an aqueous phase and an oil phase, the composition comprising inorganic powder surface-treated with a hydrophilic coating agent and dispersed in the water phase, and It has a multi-layered structure containing ceramide.

According to a specific embodiment, the ceramide layered structure includes a glucoside surfactant and the hydrophilic coating agent includes at least one of silicon dioxide and cellulose, in order to provide an excellent moisturizing effect and a recovery barrier One of the functional effects is a cosmetic composition for makeup.

According to another embodiment, silicon dioxide and cellulose can be obtained through traditional methods. However, for those skilled in the art, silicon dioxide is obviously not limited to a specific category, as long as it is within the scope of this specification.

According to yet another embodiment, an oil-in-water cosmetic composition is provided, wherein the inorganic powder surface-treated with a hydrophilic coating agent may include an amount of 2-15 wt% based on the weight of the inorganic powder One coating agent.

In particular, the inorganic powder surface-treated with a hydrophilic coating agent may include the following amount of coating agent: at least 2wt%, at least 3wt%, at least 4wt%, at least 5wt%, at least 6wt%, at least 7wt%, At least 8wt%, at least 9wt% or at least 10wt%.

Moreover, the inorganic powder surface-treated with a hydrophilic coating agent may include one of the following amounts of coating agent: at most 12wt%, at most 11wt%, at most 10wt%, at most 9wt%, at most 8wt%, at most 7wt%, At most 6wt%, at most 5wt%, at most 4wt% or at most 3wt%.

When the coating agent is used within the above range, the cosmetic composition may include the inorganic powder and at the same time contain the stable ceramide lamellar liquid crystal.

According to yet another specific embodiment, when the coating agent is a silicon dioxide coating, the titanium dioxide and yellow iron oxide in the inorganic powder may be coated at a ratio of 8-12wt%, and red or black iron oxide It may be coated at a ratio of 10-15wt%. According to another specific embodiment, when the coating agent is a cellulose coating, titanium dioxide, yellow iron oxide, red or black iron oxide may be coated at a ratio of 2-8 wt%.

According to yet another specific embodiment, an oil-in-water cosmetic cosmetic composition is provided, wherein the multi-layered structure may include a glucoside surfactant. In particular, the glucoside surfactant may be at least one selected from the group consisting of behenyl alcohol, arachidyl alcohol, arachidyl glucoside, C14-C22 alcohol and C12-C20 alkyl glucoside group.

The multilayer ceramide layered structure used herein may further include wax or oil. The wax can be at least one selected from the group consisting of alcohol, fatty acid, vegetable wax, synthetic wax, paraffin, cetyl palmitate, beeswax, lipid, and lipid peptides. The oil can be ester oil, hydrocarbon oil or silicone oil.

According to still another specific embodiment, the ceramide may be at least one of natural ceramide and ceramide-like.

The ceramide used herein may be at least one of natural ceramide and ceramide-like. The natural ceramide is a naturally occurring ceramide and contains ceramide 1, ceramide 2, ceramide 3, ceramide 4, ceramide 5, ceramide 6, ceramide 7, nerve Amide 8 and so on. Ceramides of this type include Ceramide 104 and Ceramide 102. The type of ceramide used herein generally encompasses a compound having a double-stranded layered structure, which is the structure of natural ceramide.

According to this specification, the layered structure avoids gelation of ceramides in its outer layer. When the macroemulsion is formed with two or more layered structures surrounded by multiple layers, it can help stabilize the ceramide and provide excellent pick-up properties and refreshing use sense.

When the curvature decreases and the radius of curvature increases, it is known that most rod-type surfactants (SAAs) (including ceramide) are more stable. Therefore, a macroemulsion with a smaller curvature is more stable than a small particle emulsion with a greater curvature.

According to still another specific embodiment, an oil-in-water cosmetic cosmetic composition is provided, wherein the ceramide is at least one of the compounds represented by the following chemical formulas 1-6.

(Where R is C9-C21 saturated or unsaturated fatty chain)

(Where n is 1 or 2; and each R and R'is a C9-C21 saturated or unsaturated fatty chain)

[Chemical formula 3]

[Where m and n are the same or different and each represents an integer of 1-3; k and l are the same or different and each represents 1 or 2; j is 0 or 1; R and R'are the same or different and each represents C1-C31 straight Chain or branched saturated or unsaturated alkyl group, which contains or does not contain a hydroxyl group; A ¹ , A ² and A ^{3 are the} same or different and each represents H or any substituent represented by the following structure , Provided that A ¹ , A ² and A ³ cannot simultaneously represent H:

(Wherein each of M, M ¹ and M ² is selected from the group consisting of alkaline metal, lysine, arginine, histidine, triethanolamine, amine, polyquaternium-4, polyquaternium -6, polyquaternium-7, polyquaternium-10, polyquaternium-11, polyquaternium-16, dodecyldimethylbenzylammonium chloride and octadecyldimethyl Benzyl ammonium chloride, and L is an alkaline earth metal)]

[Where R and R'are the same or different and each represents a C10-C32 linear or branched saturated or unsaturated alkyl group, which contains or does not contain a hydroxyl group; R ³ and R ^{4 are the} same or different and each Represents H or a C1-C4 alkyl group or a hydroxyalkyl group; and R ⁵ is -A or -CH ₂ CH ₂ OA, where A is any substituent represented by the following structure:

(Wherein each of M, M ¹ and M ² is selected from the group consisting of alkaline metal, lysine, arginine, histidine, triethanolamine, amine, polyquaternium-4, polyquaternium -6, polyquaternium-7, polyquaternium-10, polyquaternium-11, polyquaternium-16, dodecyldimethylbenzylammonium chloride and octadecyldimethyl Benzyl ammonium chloride, and L is an alkaline earth metal)]

[Where m and n are the same or different and each represents an integer of 1-4; R and R'are the same or different and each represents a C1-C31 linear or branched saturated or unsaturated alkyl group, which contains or does not contain A hydroxyl group; and A ₁ and A _{2 are the} same or different and each represents H or any substituent represented by the following structure:

(Wherein M, M ¹ and M ² are selected from alkaline metals, lysine, arginine, histidine, triethanolamine, amine, polyquaternium-4, polyquaternium- 6. Polyquaternium-7, polyquaternium-10, polyquaternium-11, polyquaternium-16, dodecyldimethylbenzylammonium chloride and octadecyldimethyl The group consisting of benzyl ammonium chloride, and L is an alkaline earth metal)]

[Where m and n are the same or different and each represents an integer of 1-3; k and l are the same or different and each represents 1 or 2; j is 0 or 1; A ¹ , A ² and A ^{3 are the} same or different and each represents H or any substituent represented by the following structure:

(Wherein each of M, M ¹ and M ² is an alkaline metal or nitrogen-containing organic base, and L is an alkaline earth metal); R is a substituent with the following structure:

(B is the methyl group at 5-, 7- or 8-position of tocopherol, m is an integer of 1-3, and D is -CH ₂ (CH ₃ )-CH- or -CH(CH ₃ )=C -)].

The compounds represented by chemical formulas 1-6 are ceramides that have excellent skin moisturizing properties and skin barrier function recovery effects.

As used herein, the multilayer ceramide layer structure, that is, the multilayer layered liquid crystal refers to the macroemulsion. Preferably, the multilayer ceramide layer structure, that is, the multilayer liquid crystal may have an average particle size of 2 μm-30 μm. In particular, the multilayer liquid crystal may have an average particle size of at least 2μm, at least 3μm, at least 4μm, at least 5μm, at least 6μm, at least 7μm, at least 8μm, at least 9μm, at least 10μm, at least 11μm, at least 12μm, at least 13 μm, at least 14 μm, at least 15 μm, at least 16 μm, at least 17 μm, or at least 18 μm.

Furthermore, the multilayer ceramide layered structure may have the following average particle diameters: at most 30 μm, at most 29 μm, at most 28 μm, at most 27 μm, at most 26 μm, at most 25 μm, at most 24 μm, at most 23 μm, at most 22 μm, at most 21 μm, at most 20 μm , Up to 19μm, up to 18μm, up to 17μm, up to 16μm or up to 15μm.

When the multilayered ceramide layered structure has an average particle size of at least 2 μm, it may stabilize the ceramide-like structure, realize the characteristics of water-bursting use and provide improved moisturizing effect. Moreover, when the average particle size is greater than 30 μm, the stability decreases. Therefore, it is preferable to maintain the above range.

According to yet another embodiment, there is provided a cosmetic composition, wherein the inorganic powder surface-treated with a hydrophilic coating agent comprises at least one titanium dioxide selected from the group consisting of titanium dioxide surface-treated with a hydrophilic coating agent and Iron oxide surface-treated with a hydrophilic coating agent.

According to yet another embodiment, a cosmetic composition is provided, wherein the inorganic powder surface-treated with a hydrophilic coating agent is used in an amount of 0.01-25 wt% based on the total weight of the composition.

In particular, the inorganic powder surface-treated with a hydrophilic coating agent may be used in the following amounts based on the total weight of the composition: at least 0.01 wt%, at least 0.5 wt%, at least 1 wt%, at least 2 wt%, At least 3wt%, at least 4wt%, at least 5wt%, at least 6wt%, at least 7wt%, at least 8wt%, At least 9wt%, at least 10wt%, at least 11wt%, at least 12wt%, at least 13wt%, at least 14wt%, at least 15wt%, at least 16wt%, at least 17wt%, at least 18wt%, at least 19wt%, at least 20wt% or at least 21wt %.

Moreover, the inorganic powder surface-treated with a hydrophilic coating agent may be used in the following amounts: at most 25wt%, at most 24wt%, at most 23wt%, at most 22wt%, at most 21wt%, at most 20wt%, at most 19wt%, At most 18wt%, at most 17wt%, at most 16wt%, at most 14wt%, at most 13wt%, at most 12wt% or at most 11wt%.

When the amount of the inorganic powder surface-treated with a hydrophilic coating agent is in the above range, it may provide an excellent coating effect, so that the titanium dioxide is within the limits of its formulation, and the display is not too dark nor too bright The color.

According to still another specific embodiment, the inorganic pigment surface-treated with silica or cellulose may be obtained by a person skilled in the art by a known method without specific restrictions. Usually, inorganic pigments are dispersed and a precursor of silicon dioxide (such as tetraethoxysilane) is added to it, and then hydrolyzed by heat treatment at a temperature of 50-400°C for 1-6 hours to make the inorganic The pigment may be surface treated with silica. Specific examples of the inorganic pigment may include titanium dioxide and yellow, red and black iron oxides, but are not limited thereto.

According to yet another embodiment, it is possible to use titanium dioxide and yellow, red and black iron oxides surface-treated with silicon dioxide or cellulose. In the case of titanium dioxide surface-treated with silicon dioxide or cellulose, it preferably has a particle size of 400-600nm to provide coating effects and it is preferably 0.5-25wt% based on the total weight of the composition量用。 The amount of use. When the amount is less than 0.5wt%, it may provide sufficient coating effect. When the amount is greater than 25wt%, it exceeds the titanium dioxide formulation limit.

Moreover, the yellow, red and black iron oxide surface-treated with silica or cellulose are used in an amount determined by the color, and it is preferably used in a combined amount of 0.01-10 wt% based on the total weight of the composition. When the amount is less than 0.01wt%, it is possible to achieve the desired color. When the amount is greater than 10 wt%, the composition is too dark and therefore unsuitable for cosmetic compositions.

According to yet another specific embodiment, a cosmetic composition is provided, wherein the ceramide is used in an amount of 0.01-20 wt% based on the total weight of the composition.

In particular, the ceramide may be used in the following amounts based on the total weight of the composition: at least 0.01 wt%, at least 0.5 wt%, at least 1 wt%, at least 2 wt%, at least 3 wt%, at least 4 wt%, at least 5 wt% , At least 6wt%, at least 7wt%, at least 8wt%, at least 9wt%, at least 10wt%, at least 11wt%, at least 12wt%, at least 13wt%, at least 14wt%, at least 15wt%, at least 16wt% or at least 17wt%.

Moreover, the ceramide may be used in the following amounts based on the total weight of the composition: at most 20wt%, at most 19wt%, at most 18wt%, at most 17wt%, at most 16wt%, at most 15wt%, at most 14wt%, at most 13wt %, up to 12wt% or up to 11wt%.

When the ceramide is used in the above range, it may provide excellent skin moisturizing effect and improve skin dryness when applied to the skin.

In another aspect, a method for preparing an oil-in-water cosmetic cosmetic composition is provided, which includes the following steps: preparing an oil phase, which includes ceramide and glucoside surfactant; and preparing an aqueous phase Mixing with inorganic powder surface-treated with a hydrophilic coating agent to disperse the powder; mixing the prepared oil phase with the water phase to form a mixture; and placing the mixture at 45°C-60°C.

In still another aspect, a method for preparing an oil-in-water cosmetic composition is provided, which includes the following steps: preparing an oil phase, which includes a ceramide and a glucoside surface Active agent; preparing an aqueous phase; mixing the prepared oil phase with the water phase to form a mixture; placing the mixture at 45°C-60°C; and surface-treating the mixture with a hydrophilic coating agent The inorganic powder is mixed to disperse the powder.

According to a specific embodiment, the step of allowing the mixture to stand still plays an important role in forming the layered structure.

In particular, the step of allowing the mixture to stand may be performed at the following temperatures: at least 45°C, at least 46°C, at least 47°C, at least 48°C, at least 49°C, at least 50°C, at least 51°C, at least 52°C, at least 53°C ℃ or at least 54℃.

Moreover, the step of allowing the mixture to stand may be carried out at the following temperatures: at most 60°C, at most 59°C, at most 58°C, at most 57°C, at most 56°C, at most 55°C, at most 54°C, at most 53°C, at most 52°C , Up to 51°C or up to 50°C.

When the temperature is in the above range, a layered structure will be formed stably.

According to another specific embodiment, the step of allowing the mixture to stand may be performed for at least 20 minutes, at least 25 minutes, at least 30 minutes, at least 35 minutes, at least 40 minutes, at least 50 minutes, at least 60 minutes, at least 70 minutes, at least 80 minutes. Minutes or at least 100 minutes.

When the time is within the above range, a layered structure will form stably.

According to yet another embodiment, the hydrophilic coating agent includes at least one selected from silica and cellulose.

According to yet another specific embodiment, the glucoside surfactant is selected from the group consisting of behenyl alcohol, arachidyl alcohol, arachidyl glucoside, C14-22 alcohol and C12-20 alkyl glucoside At least one of the groups.

The cosmetic composition of the present specification may be formulated as an oil-in-water makeup base or foundation containing a coloring agent, but it is not limited thereto.

Invention embodiment

Hereinafter, this specification will describe in detail with reference to Examples and Comparative Examples. However, the following examples are for illustrative purposes only, and are not intended to limit the scope of this specification. Those skilled in the art should understand that the following examples and test examples can be substituted and inserted without departing from the spirit and scope of this specification as defined by the appended claims.

Examples 1 and 2 and Comparative Examples 1 and 2

The oil-in-water cosmetic cosmetic compositions of Examples 1 and 2 and Comparative Examples 1 and 2 were prepared according to the compositions shown in Table 1 below. Inorganic powder surface-treated with alkyl silanes (OTS series can be obtained from Daito Kasei, in all cases with 2% coating) / silicon dioxide (Sympholight series can be obtained from JGC Catalysts and Chemicals Ltd., in titanium dioxide and yellow iron oxide In the case of 10% coating, in the case of red/black iron oxide, 12% coating)/cellulose (C2 series can be obtained from Daito Kasei, in all cases 5% coating) is commercially available的产品。 The product.

1) An oil phase solution is prepared according to the composition in Table 1 at 75°C. For ceramides, hydroxypropyl dipalmitamide MEA (Pc104) and hydroxypropyl dipaluramide MEA (Pc102) are used.

2) In a separate container, an aqueous phase solution is prepared at 75°C, mixed with a colorant and dispersed in the aqueous phase solution (in the case of the alkyl silane of Comparative Example 2, it is mixed with a colorant Mix and disperse in the oil phase solution).

3) The oil phase solution of step 1) is added to the water phase solution of step 2), and the resulting mixture is stirred and mixed using a homomixer.

4) The mixture is kept at a cooling temperature of about 52°C for about 35 minutes, cooled to 30°C, and then completely degassed to obtain an oil-in-water cosmetic composition.

Examples 3 and 4 and Comparative Examples 3-5

The oil-in-water cosmetic cosmetic compositions of Examples 3 and 4 and Comparative Examples 3, 4, and 5 were prepared according to the compositions shown in Table 2 below.

1) An oil phase solution was prepared according to the composition in Table 2 at 75°C. For ceramides, hydroxypropyl dipalmitamide MEA (Pc104) and hydroxypropyl dipaluramide MEA (Pc102) are used.

2) In a separate container, an aqueous solution is prepared at 75°C.

3) The oil phase solution of step 1) is added to the water phase solution of step 2), and the resulting mixture is stirred and mixed using a homomixer.

4) The mixture is kept at a cooling temperature of about 52°C for about 35 minutes, mixed with a colorant and dispersed in the mixture.

5) The temperature of the mixture is lowered to 3°C, and then completely degassed to obtain an oil-in-water cosmetic composition.

[Test Example 1] Comparison of stability

In order to determine the stability of the cosmetic composition formulation of this specification, 10g of each of Examples 1-4 and Comparative Examples 1-5 was taken out and each sample was introduced into a cryostat (4°C), 30°C), a high temperature thermostat (45°C) and a cycle chamber (cycle chamber) that cycles from -10°C to 45°C for 24 hours. Observe the changes in the formulation to determine the stability. The results are shown in Tables 3 and 4 below.

As can be seen from the results in Table 3, Comparative Example 1 shows poor stability because the layered structure is destroyed by the uncoated (unsurface-treated) inorganic powder, resulting in demulsification. Coating ratio of hydrophobic alkyl silane Compared with Example 2, the formulation itself cannot be formed because of the phase inversion during the preparation process. Examples 1 and 2 coated with hydrophilic cellulose and silicon dioxide formed multilayer lamellar liquid crystals, which had a particle size of 2 μm or more, but were slightly unstable in terms of long-term stability at 45°C.

A different method is used to prepare multilayer lamellar liquid crystals by keeping the reaction mixture at about 52°C for about 35 minutes and dispersing a different type of pigment in it. The results are shown in Table 4. It can be seen that Comparative Example 3 shows a low output value because the previously formed multilayer layered structure is destroyed by the non-surface-treated inorganic powder and the particle size is excessively reduced, resulting in gelation at 45°C. Comparative Example 4 had no output value because the inorganic powder coated with hydrophobic alkylsilane was introduced after forming the oil-in-water emulsion, and the powder could not be uniformly dispersed in the emulsion. In contrast, Examples 3 and 4 coated with hydrophilic cellulose and silicon dioxide maintained the previously formed multilayer lamellar liquid crystal and were stable at 45° C. for 6 months, thus exhibiting excellent phase stability. This shows that the use of hydrophilic materials in the ceramide-like composition The surface-treated inorganic powder provides the excellent effect of avoiding the gelation of this type of ceramide while maintaining the multilayer lamellar liquid crystal.

Comparative Example 5 has no gelation and is stable because it does not contain ceramide.

[Test Example 2] Evaluation of skin moisture retention

In order to determine the moisture retention of the skin after applying the cosmetic composition, 80 adult men and women in their thirties or forties were each applied the cosmetic composition of Examples 3 and 4 and Comparative Example 5 Place objects on his face and inner forearm. Then, a corneometer (CM820 courage Khazaka electronic GmbH, Germany) was used to measure the skin water content for 24 hours. Before applying each composition, the skin moisture content was measured using the epidermal moisture tester under constant temperature and humidity conditions (24°C, humidity 40%), and the measured value was taken as a reference value. Furthermore, the change in skin water content was measured at the time after use, after 2 hours of use, 4 hours after use, and 8 hours after use. The results are shown in Table 5 below.

<Measured value by epidermal moisture tester>

Principle: The amount of water in the epidermis is determined by the following methods to determine the moisturizing effect: measuring the ionic strength of the water with a sensor, digitizing the ionic strength, and calculating the water amount.

1) An epidermal moisture tester probe is placed on a predetermined position of the skin.

2) When the probe is pressed against the skin, the capacitance of the skin is digitized by the sensor and displayed on the screen.

3) Once confirmed, wipe the sensor with a wipe paper (such as Kim Wipe) and use it repeatedly in different positions to confirm.

[table 5]

From the results in Table 5, it can be seen that the cosmetic cosmetic compositions of Examples 3 and 4 containing ceramide in this specification, compared to Comparative Example 5 without ceramide, show a higher increase in skin water content after use , And such increased skin moisturizing effect can be maintained for at least 8 hours.

Furthermore, after completing the test, the test group was investigated to check the effect of improving skin dryness after using each cosmetic composition. The evaluation results of the average value are shown in Table 6 below (5-point scale).

The results in Table 6 show that, compared with Comparative Example 5, the cosmetic composition of Examples 3 and 4 that stabilized ceramide by using inorganic powder surface-treated with a hydrophilic material showed improvement in dry skin Significantly higher effect.

Claims (14)

An oil-in-water cosmetic cosmetic composition, comprising an aqueous phase and an oil phase, the composition comprising inorganic powder surface-treated with a hydrophilic coating agent and dispersed in the aqueous phase, and has a nerve-containing A multi-layered structure of amide; wherein the hydrophilic coating agent includes at least one selected from silica and cellulose. The oil-in-water cosmetic composition according to claim 1, wherein the inorganic powder surface-treated with a hydrophilic coating agent includes a coating agent in a proportion of 2-15 wt% based on the total weight of the inorganic powder. The oil-in-water cosmetic composition according to claim 1, wherein the multi-layered structure includes a glucoside surfactant. The oil-in-water cosmetic cosmetic composition according to claim 3, wherein the glucoside surfactant is at least one selected from the group consisting of C14-22 alcohol and C12-20 alkyl glucoside. The oil-in-water cosmetic composition according to claim 3, wherein the glucoside surfactant is selected from the group consisting of behenyl alcohol, arachidyl alcohol, and arachidyl glucoside At least one. The oil-in-water cosmetic composition according to claim 1, wherein the ceramide is selected from at least one of natural ceramide and ceramide-like ceramide. The oil-in-water cosmetic cosmetic composition according to claim 6, wherein the natural ceramide is selected from ceramide 1, ceramide 2, ceramide 3, ceramide 4, ceramide 5 , At least one of ceramide 6, ceramide 7, and ceramide 8. The oil-in-water cosmetic composition according to claim 6, wherein the ceramide is selected from at least one of the compounds represented by the following chemical formulas 1-6:

(Where R is C9-C21 saturated or unsaturated fatty chain)

(Where n is 1 or 2; and each R and R'is a C9-C21 saturated or unsaturated fatty chain)

[Where m and n are the same or different and each represents an integer of 1-3; k and l are the same or different and each represents 1 or 2; j is 0 or 1; R and R'are the same or different and each represents C1-C31 straight Chain or branched saturated or unsaturated alkyl group, which contains or does not contain a hydroxyl group; A ¹ , A ² and A ^{3 are the} same or different and each represents H or any substituent represented by the following structure , Provided that A ¹ , A ² and A ³ cannot simultaneously represent H:

(Wherein each of M, M ¹ and M ² is selected from the group consisting of alkaline metal, lysine, arginine, histidine, triethanolamine, amine, polyquaternium-4, polyquaternium -6, polyquaternium-7, polyquaternium-10, polyquaternium-11, polyquaternium-16, dodecyldimethylbenzylammonium chloride and octadecyldimethyl Benzyl ammonium chloride, and L is an alkaline earth metal)]

[Where R and R'are the same or different and each represents a C10-C32 linear or branched saturated or unsaturated alkyl group, which contains or does not contain a hydroxyl group; R ³ and R ^{4 are the} same or different and each Represents H or a C1-C4 alkyl group or a hydroxyalkyl group; and R ⁵ is -A or -CH ₂ CH ₂ OA, where A is any substituent represented by the following structure:

(Wherein each of M, M ¹ and M ² is selected from the group consisting of alkaline metal, lysine, arginine, histidine, triethanolamine, amine, polyquaternium-4, polyquaternium -6, polyquaternium-7, polyquaternium-10, polyquaternium-11, polyquaternium-16, dodecyldimethylbenzylammonium chloride and octadecyldimethyl Benzyl ammonium chloride, and L is an alkaline earth metal)]

[Where m and n are the same or different and each represents an integer of 1-4; R and R'are the same or different and each represents a C1-C31 linear or branched saturated or unsaturated alkyl group, which contains or does not contain A hydroxyl group; and A ₁ and A _{2 are the} same or different and each represents H or any substituent represented by the following structure:

(Wherein M, M ¹ and M ² are selected from alkaline metals, lysine, arginine, histidine, triethanolamine, amine, polyquaternium-4, polyquaternium- 6. Polyquaternium-7, Polyquaternium-10, Polyquaternium-11, Polyquaternium-16, Dodecyldimethylbenzylammonium chloride and octadecyldimethyl The group consisting of benzyl ammonium chloride, and L is an alkaline earth metal)]

[Where m and n are the same or different and each represents an integer of 1-3; k and l are the same or different and each represents 1 or 2; j is 0 or 1; A ¹ , A ² and A ^{3 are the} same or different and each represents H or any substituent represented by the following structure:

(Wherein each of M, M ¹ and M ² is an alkaline metal or nitrogen-containing organic base, and L is an alkaline earth metal); R is a substituent with the following structure:

(B is the methyl group at 5-, 7- or 8-position of tocopherol, m is an integer of 1-3, and D is -CH ₂ (CH ₃ )-CH- or -CH(CH ₃ )=C -)]. The oil-in-water cosmetic cosmetic composition according to claim 1, wherein the inorganic powder surface-treated with a hydrophilic coating agent includes at least one selected from titanium dioxide that has been surface-treated with a hydrophilic coating agent and Iron oxide surface-treated with a hydrophilic coating agent. The oil-in-water cosmetic cosmetic composition according to claim 1, wherein the inorganic powder surface-treated with a hydrophilic coating agent is used in an amount of 0.01-25 wt% based on the total weight of the composition. The oil-in-water cosmetic composition according to claim 1, wherein the ceramide is used in an amount of 0.01-20 wt% based on the total weight of the composition. The oil-in-water cosmetic cosmetic composition according to claim 1, wherein the layered structure has a size of 2 μm-30 μm. A method for preparing any one of the oil-in-water cosmetic cosmetic compositions according to claims 1 to 12, which comprises the following steps: 1. An oil phase is prepared, which includes a ceramide and a glucoside surface Active agent; 2. Mix an aqueous phase with an inorganic powder surface-treated with a hydrophilic coating agent to disperse the powder; 3. Mix the prepared oil phase with the water phase to form a mixture; and 4 . Put the mixture at 45°C-60°C. A method for preparing any one of the oil-in-water cosmetic cosmetic compositions according to claims 1 to 12, which comprises the following steps: 1. An oil phase is prepared, which includes a ceramide and a glucoside surface Active agent; 2. preparing an aqueous phase; 3. mixing the prepared oil phase with the aqueous phase to form a mixture; 4. placing the mixture at 45°C-60°C; and 5. making the mixture and The inorganic powder surface-treated with the hydrophilic coating agent is mixed to disperse the powder.