TWI701053B - Emulsified composition - Google Patents

Abstract

The purpose of the present invention is to provide an emulsified composition that contains more than 5 wt% of clay minerals while improving the feeling of use of the skin (extensibility, adhesion to the skin, uneven color, residual white matter).

The present invention is an emulsified composition containing an acid selected from the group consisting of hydrochloric acid, sulfuric acid, nitric acid, and phosphoric acid, and at least 5% by weight of clay minerals.

Description

Emulsified composition

The present invention relates to emulsified compositions.

Previously, there are known compositions for other than clay minerals such as kaolin and bentonite. However, since clay minerals have a large specific gravity and are easy to precipitate, when these substances are mixed in a large amount of 5 wt% or more, a stable composition cannot be prepared. Therefore, as a method to solve this problem, methods such as surface treatment of clay minerals to improve the dispersibility have been proposed previously (see, for example, Patent Documents 1 and 2). However, the surface treatment of clay minerals has the problem of complicated and time-consuming operations.

In addition, an external composition containing a large amount of clay minerals at more than 5% by weight will not only have poor adhesion to the skin and not easily spread on the skin, but also have problems such as uneven color and white residue. A satisfying sense of use.

For external skin preparations such as emulsions, a method of mixing fatty acid metal soaps is known for the purpose of preventing the sedimentation (caking, caking) of powders (Patent Document 3). However, in an external composition containing a large amount of clay minerals as a powder at 5% by weight or more, even by mixing fatty acid gold The genus soap improves the dispersibility, but the feeling of use of the external agent (adhesion to the skin, degree of easy spreading, uneven color, white residue) is not good, and it is difficult to prepare the external composition that can give the user full satisfaction Things.

[Prior Technical Document]

[Patent Document]

[Patent Document 1] International Publication No. 2007/111335 Specification

[Patent Document 2] JP 8-208218 Bulletin

[Patent Document 3] JP 2002-193739 No.

The present invention is to provide an emulsified composition that has a good feeling of use on the skin (adhesion to the skin, easy extensibility, no color unevenness and/or white residue) even though it contains more than 5% by weight of clay minerals. purpose. Specifically, the purpose is to provide an emulsified composition that has good adhesion to the skin, easily spreads on the skin, and has no color unevenness and/or white residue.

Furthermore, the present invention provides an emulsified composition containing 5% by weight or more of clay minerals, and provides an improved feeling of use on the skin (adhesion to the skin, easy spreadability, no color unevenness and/or white residue) The method is the purpose. Specifically, for the above-mentioned emulsified composition, a method for improving the degree of adhesion to the skin is provided, The purpose is to improve the spreading feeling, improve the uneven color, and/or improve the white residue.

In order to solve the above-mentioned problems, the team of the present invention found that in the emulsified composition containing clay minerals, by mixing at least one acid selected from the group of hydrochloric acid, sulfuric acid, nitric acid, and phosphoric acid, even if the amount is more than 5 wt% When a large amount of clay minerals are mixed, it can be made into a composition that has a good fit to the skin, and is easy to spread on the skin during use, and has no uneven color and white residue.

In addition, the team of the present invention found in the above review process that when the emulsified composition is further mixed with metal oxides and heparinoid substances, the dispersion stability of clay minerals and powders in the emulsified composition can be improved, thereby also improving the coloring properties. .

The present invention was completed on the basis of these findings, and has the following embodiments.

(I) Emulsified composition

(I-1) An emulsified composition containing at least one acid selected from the group consisting of hydrochloric acid, sulfuric acid, nitric acid, and phosphoric acid, and at least 5% by weight of clay minerals.

(I-2) The emulsified composition as in (I-1), which further contains metal oxides, and more preferably contains iron oxide.

(I-3) The emulsified composition of (I-1) or (I-2), in which clay minerals The content is 5-15% by weight.

(I-4) The emulsified composition as in any one of (I-1) to (I-3) has a pH of 4 to 8, preferably pH 4 to 7.

(I-5) The emulsified composition of any one of (I-1) to (I-4), which does not contain a thickener.

(I-6) The emulsified composition of any one of (I-1) to (I-5), which further contains a white pigment.

(I-7) The emulsified composition of any one of (I-1) to (I-6), which further contains a heparinoid substance.

(II) Methods to improve skin feeling

(II-1) A method for improving the feeling of use of the skin, which is in an emulsified composition containing at least 5% by weight of clay minerals, and at least one acid selected from the group consisting of hydrochloric acid, sulfuric acid, nitric acid and phosphoric acid .

(II-2) The method as in (II-1), wherein the clay mineral content is 5-15% by weight.

(II-3) The method as (II-1) or (II-2), wherein in the emulsified composition containing at least 5% by weight of clay minerals, the above-mentioned acids are combined and the pH is 4 to 8, more preferably It has steps to adjust pH 4~7.

(II-4) The method according to any one of (II-1) to (II-3), wherein the emulsified composition does not contain a thickener.

(II-5) The method according to any one of (II-1) to (II-4), wherein the emulsified composition system further contains a white pigment.

(II-6) The method of any one of (II-1) to (II-5), wherein the above The emulsified composition system further contains metal oxides, and more preferably contains iron oxide.

(II-7) The method according to any one of (II-1) to (II-6), wherein the emulsified composition system further contains a heparinoid substance.

(II-8) As in the method of any one of (II-1) to (II-7), the skin use feeling is the degree of adhesion to the skin and/or the degree of easy extension to the skin.

(II-9) As in the method of any one of (II-1) to (II-8), the skin feeling is not easy to have uneven color and/or white residue on the skin.

(III) Dispersion stabilization method/improving coloring method

(III-1) A method for dispersing and stabilizing the clay minerals of the above-mentioned emulsified composition, which is based on the emulsified composition containing at least 5% by weight of clay minerals, at least one selected from hydrochloric acid, sulfuric acid, nitric acid and phosphoric acid Groups of acids, metal oxides, and heparinoid substances coexist.

(III-2) The method according to (III-1), wherein the metal oxide is iron oxide.

(III-3) The method as (III-1) or (III-2), wherein the clay mineral content is 5-15% by weight.

(III-4) The method of any one of (III-1) to (III-3), wherein in the emulsified composition containing at least 5 wt% clay minerals, the above-mentioned acids are combined and the pH is 4-8 , It is better to have steps to adjust pH 4~7.

(III-5) The method according to any one of (III-1) to (III-4), wherein the emulsified composition system does not contain a thickener.

Although the emulsified composition of the present invention contains a large amount of clay minerals of 5 wt% or more, at least one acid selected from the group consisting of hydrochloric acid, sulfuric acid, nitric acid and phosphoric acid is used to adjust the pH (pH 4~8, more preferably pH 4~ 7) As a result, the feeling of use when applied to the skin as an external composition is significantly improved and improved compared to the emulsified composition (control emulsified composition) whose pH is adjusted by using organic acids instead of the aforementioned acids. Specifically, compared with the aforementioned control emulsion composition, the emulsified composition of the present invention is characterized by better adhesion to the skin and/or easy extension to the skin. In addition, compared with the aforementioned control emulsion composition, the emulsified composition of the present invention is characterized in that it is less prone to color unevenness and/or less likely to remain white. From this result, it can be seen that the emulsified composition of the present invention can improve the feeling in use when applied to the skin, and from the viewpoint of feeling in use, it is possible to provide a high-quality emulsified composition.

In addition to adding at least one acid selected from the group consisting of hydrochloric acid, sulfuric acid, nitric acid and phosphoric acid, the emulsified composition of the present invention can improve the dispersion stability of clay minerals and other powders by blending metal oxides and heparins, and / Or, can improve the coloring of metal oxides (iron oxide, etc.). Therefore, it can be seen that the emulsified composition of the present invention can improve the feeling of use and appearance when applied to the skin. As a result, it is possible to provide a high-quality emulsified composition from the viewpoint of feeling of use and appearance.

(I) Emulsified composition

The emulsified composition of the present invention is characterized by containing at least 5% by weight of clay minerals and at least one acid selected from the group consisting of hydrochloric acid, sulfuric acid, nitric acid and phosphoric acid (hereinafter referred to as "mineral acid"). In addition, the emulsified composition is formed of a water phase containing an aqueous component and an oil phase containing an oil component.

Hereinafter, each component constituting the emulsified composition of the present invention will be described.

(1-1) Essential ingredients

(a) Clay minerals

The emulsified composition of the present invention is characterized by containing clay minerals. It is sufficient if the content of the clay mineral is at least 5% by weight. It is not particularly limited, but is preferably about 5 to 20% by weight, more preferably 5 to 15% by weight.

The types of clay minerals that can be used in the present invention are not particularly limited. Examples include bentonite group clay minerals such as bentonite, montmorillonite, saponite, hectorite, and zeolite; vermiculite clay minerals such as vermiculite; Kaolin, hydrokaolin, pearl clay, double kaolin, white asbestos and other kaolin clay minerals. These minerals may be used singly or in combination of two or more types. The clay minerals used can be appropriately selected from the clay minerals according to the type and quantity of mineral acids used in combination. Preferably, it is bentonite in the clay mineral of the bentonite group, and kaolin in the clay mineral of the kaolin system. These clay minerals can be purchased through commercial models. For example, bentonite is commercially available as Bengeru (manufactured by Japan Organoclay Co., Ltd.), BenntoraitoH (manufactured by Southern Clay Products), BentonnMA, BenntonnEW and BenntonnLT (manufactured by Elementis Corporation), etc. Kaolin is commercially available as kaolin (manufactured by Katsukoyama Mining Co., Ltd.), KaorinnJP-100 (manufactured by Takehara Chemical Industry Co., Ltd.), and NN Kaorinnkure (manufactured by Dongshin Chemical Co., Ltd.).

(b) Mineral acid

As mentioned earlier, the emulsified composition is characterized by not only clay minerals but also specific mineral acids.

The mineral acid used in the present invention includes hydrochloric acid, sulfuric acid, nitric acid, and phosphoric acid. These acids can be used individually by 1 type, and can also be used in combination of 2 or more types arbitrarily. Preferred are hydrochloric acid and phosphoric acid, and more preferred is hydrochloric acid.

Mineral acid acts as a pH adjuster. Therefore, the blending ratio of mineral acid in the emulsified composition of the present invention may include that the pH of the emulsified composition is finally pH 4~8, preferably pH 4~7, and more preferably pH The ratio of 4~6.

In addition, when a general acid is blended in the aforementioned clay mineral-containing composition, the clay mineral may easily aggregate and become hard. Therefore, there is a tendency that it is not easy to extend on the skin (the extensibility is reduced), and the adhesion to the skin becomes poor. In view of this defect, by using the above-mentioned specific mineral acid as the acid, even if the pH of the emulsified composition is 7 or less, especially when the acidic condition is adjusted to pH 6 or less, it is not only easy to stretch (improve ductility), but also affects the skin. With good adhesion, it can prepare a good emulsified composition that suppresses uneven color and white residue.

(c) Water-based ingredients

The aqueous component forming the water phase of the emulsion composition of the present invention includes water, monohydric alcohol, polyhydric alcohol, and the like.

The type of water is not particularly limited. Without limitation, pure water, distilled water, ion-exchange water, sterilized water, physiological saline, and deep ocean water can be used. Preferably it is pure water. The content of water in the emulsified composition of the present invention is generally selected to be adjusted to a range of about 10 to 90% by weight, preferably about 20 to 80% by weight, more preferably about 30 to 70% by weight.

Examples of monohydric alcohols include monohydric alcohols having 1 to 4 carbon atoms. Specifically, for example, methanol, ethanol, propanol, isopropanol, etc. are mentioned. Monohydric alcohols may be used alone or in combination of two or more types.

Examples of polyols include polyols having 2 to 6 carbon atoms and 2 to 3 oxygen numbers. Specifically, for example, ethylene glycol, diethylene glycol, propylene glycol, 1,3-propanediol, dipropylene glycol, 1,3-butanediol, 1,2-pentanediol, 1,2-hexanediol Alcohol, 3-methyl-1,3-butanediol, glycerin, and sorbitol, etc. Among them, propylene glycol, dipropylene glycol, 1,3-butanediol, 1,2-pentanediol are preferred, and 1,3-butanediol is more preferred. A polyhydric alcohol may be used individually by 1 type, and may be used combining two or more types arbitrarily.

The content of monohydric alcohol or polyhydric alcohol in the emulsified composition is generally selected to be adjusted to a range of about 1 to 10% by weight, preferably about 1 to 8% by weight, and more preferably about 1 to 5% by weight.

(d) Oily ingredients

The oily components that form the oil phase of the emulsified composition of the present invention include common The temperature (25°C) is liquid, oily components, etc.

The oily ingredients that are liquid at room temperature are not particularly limited if they are permitted to be used in the fields of medicines, quasi-drugs, cosmetics, and food. For example, it is better to use aliphatic alcohols which are liquid at room temperature. Examples of oily components that are liquid at room temperature include liquid alcohols such as hexyldecanol, octyldodecanol, decyltetradecyl alcohol, oleyl alcohol, and lauryl alcohol. Preferred are hexyldecanol and octyldodecanol, and more preferred are hexyldecanol. Oily components that are liquid at room temperature. Silicon dioxide oil, mineral oil, vegetable oil, liquid paraffin, and ester oil can also be used.

These oily components can be used individually by 1 type, and can also be used combining two or more types arbitrarily.

The content of the oily component that is liquid at room temperature in the emulsified composition is generally selected and adjusted to the range of about 1 to 30% by weight. Preferably it is about 5-20% by weight, more preferably about 7-15% by weight. By making the emulsified composition contain an oily component that is liquid at room temperature in this content, the emulsified state can be stabilized, and a good emulsified state can also be maintained over a long period of time.

In addition, the emulsified composition of the present invention may further contain an oily component that is solid at room temperature (25°C). Thereby, the dispersibility of clay minerals, metal oxides (iron oxide, etc.), white pigments, etc. in the emulsified composition can be improved, and the colorability can be further improved. The oily component that is solid at room temperature functions as a base when the emulsified composition is used as a medicine such as a concealer and cosmetics such as a foundation.

Oily ingredients that are solid at room temperature. There are no special restrictions if they are approved for use in pharmaceuticals, quasi-drugs, cosmetics, and food. system. For example, it is better to use alcohols that are solid at room temperature.

Specific examples include fatty acids such as lauric acid, myristic acid, palmitic acid, stearic acid, oleic acid, and behenic acid, waxes such as beeswax, carnauba wax, lanolin wax, lanolin wax ester, and candelilla wax, Solid alcohols such as cetearyl alcohol, stearyl alcohol, cetyl alcohol (palmityl alcohol), myristyl alcohol, isostearyl alcohol, behenyl alcohol, and ovine alcohol. Preferably, cetearyl alcohol, stearyl alcohol, cetyl alcohol (palmityl alcohol), behenyl alcohol and the like are preferred.

In addition, hydrocarbon oils such as microcrystalline wax, α-olefin oligomer, gelled hydrocarbon, ozokerite, paraffin wax, and petrolatum can also be used for oily components that are solid at room temperature. Among them, it is better to use microcrystalline wax.

The oily component that is solid at room temperature may be used alone or in combination of two or more types.

The content of the oily component that is solid at room temperature in the emulsified composition of the present invention is generally selected and adjusted to the range of about 0.5 to 30% by weight. Preferably it is about 1-20% by weight, more preferably about 2-18% by weight. By making the emulsified composition contain an oily component that is solid at room temperature in this content, the emulsified state can be stabilized, and a good emulsified state can also be maintained over a long period of time. In addition, the dispersibility of metal oxides (iron oxide, etc.) and white pigments in the emulsified composition can be improved, and the colorability can be further improved.

The content of the oily component (liquid or solid at room temperature) in the emulsified composition of the present invention is generally about 1 to 60% by weight, preferably about 5 to 40% by weight, and about 10 to 35% by weight for the above reasons. %optimal.

(1-2) Arbitrary ingredients

(a) Coloring agent

When the emulsified composition is prepared into pharmaceuticals such as concealer and cosmetics such as foundation, the emulsified composition of the present invention preferably contains a coloring agent. Examples of colorants include white pigments and colored pigments that are permitted to be blended into external compositions (medical compositions, cosmetic compositions).

(a-1) Colored pigment

The purpose of using colored pigments is to color the emulsified composition of the present invention into pharmaceuticals such as concealer and cosmetics such as foundation, and to make the composition color and develop color. The colored pigments include preferably metal oxides including iron oxide.

Examples of the iron oxide include iron trioxide (red shell color), yellow iron oxide, yellow iron trioxide, and black iron oxide. These various iron oxides can be used alone or in combination of two or more in any combination.

The particle size and shape of the iron oxide are not limited, and the previously known iron oxide can be appropriately used according to the purpose. For example, the particle size of iron oxide is about 0.01 to 10 μm. It is preferably about 0.1 to 1 μm, more preferably about 0.1 to 0.8 μm. And can use laser refraction analysis to determine the particle size of iron oxide. In addition, the shape of iron oxide is preferably powder.

When a colored pigment (iron oxide) is blended in the emulsified composition of the present invention, its content (a total amount when two or more are used in combination) can be appropriately selected according to the clay mineral content used in combination, the type and content of the white pigment, and the like. The emulsified composition of the present invention is prepared as an emulsified composition suitable for skin In general, it can be selected from the range of about 0.01 to 8% by weight according to the color of the applicable skin. It is preferably about 0.1 to 5 wt%, more preferably about 1 to 3 wt%.

(a-2) White pigment

When the emulsified composition of the present invention is used as a concealer and other medicines and foundations and other cosmetics, the white pigment functions as a modulator for coloring the skin by colored pigments.

Examples of white pigments include color pigments and extender pigments. Specifically, metal oxides other than the aforementioned mineral acid and iron oxide, mica, and the like can be mentioned. Examples of metal oxides include chromium oxide, zinc oxide, titanium oxide, aluminum oxide, talc, crown talc, and the like. The white pigment is preferably titanium oxide and crown talc. In addition, ultrafine particles such as titanium oxide and zinc oxide can also be used to prevent ultraviolet rays. Titanium oxide coated mica (titanium mica) can be used as a pearl luster pigment. Titanium oxide can be used as an ultraviolet scatterer in the cosmetics field, and can be used in sunscreens, foundations, etc. Talc is mostly used to adjust gloss and feeling of use. The white pigment can be used alone according to its purpose, or two or more of them can be used in any combination.

The particle size and shape of the white pigment are not limited, and the previously known white pigments can be appropriately used according to the purpose. The particle size of the white pigment can generally be selected from the range of 0.01~10μm. It is preferably about 0.1 to 1 μm, more preferably about 0.1 to 0.8 μm. And can use laser refraction analysis to determine the particle size of the white pigment. In addition, the shape of the white pigment is preferably powder.

When white pigment is blended into the emulsified composition of the present invention, The content of the white pigment (the total amount when two or more types are used in combination) can be appropriately selected according to the content of the clay mineral to be used in combination, the type and content of colored pigments (iron oxide, etc.). When the emulsified composition of the present invention is prepared as an emulsified composition suitable for skin, it can generally be selected from the range of about 1 to 35% by weight according to the color of the applicable skin. Preferably, it is about 1 to 30% by weight, more preferably about 1 to 25% by weight.

The content (total amount) of the colored pigment (iron oxide) and the white pigment in the emulsified composition of the present invention is preferably about 1-40% by weight for the above reasons. More preferably, it is about 1 to 35% by weight, most preferably about 1 to 30% by weight.

(b) Heparinoid substances

The emulsified composition of the present invention can be blended with heparin-like substances. The heparin-like substance is a polysulfate of mucopolysaccharide, and it is better to use the one listed in the Japanese Pharmacopoeia Quasi-Drug Specification (1993).

When the emulsified composition of the present invention is used in pharmaceuticals such as concealers and cosmetics such as foundations, heparinoid substances have skin moisturizing effects and blood flow promotion effects. By blending heparin-like substances in the emulsified composition, it can be expected to restore the skin barrier function, restore the skin's luster, protect against external stimulation (moisturizing effect), activate skin metabolism, and promote skin regeneration (promoting blood circulation) ), inhibit skin inflammation and lead rough skin to a normal state (anti-inflammatory effect).

The content of the heparinoid substance in the emulsified composition of the present invention can be appropriately selected according to the type and content of the colored pigment (iron oxide) used in combination. Generally, it can be selected from the range of about 0.0005 to 10% by weight. Better line 0.001 to 3% by weight, more preferably 0.01 to 3% by weight, most preferably 0.01 to 1% by weight.

The blending ratio of the heparinoid substance and iron oxide in the emulsified composition of the present invention (the total amount when two or more kinds are used in combination) is based on 1 part by weight of the heparinoid substance, such that the iron oxide is 0.001 to 16000 parts by weight The mixing ratio is better, it is better to mix the iron oxide in the ratio of 0.02 to 5000 parts by weight, and it is also better to mix the iron oxide in the ratio of 0.2 to 30 parts by weight, and the iron oxide is mixed in the ratio of 1 to 15 parts by weight. Mix the best.

When iron oxide is contained in the emulsified composition of the present invention, the blending ratio of the total amount of heparin-like substance, iron oxide and clay minerals in the emulsified composition (the total amount when two or more are used in combination) is relative to 1 part by weight For heparin-like substances, the total amount of iron oxide and clay minerals is preferably blended in a ratio of 0.01 to 80,000 parts by weight, preferably in a ratio of 0.2 to 35,000 parts by weight, and preferably in a ratio of 1 to 300 parts by weight. , The best blending ratio is 10~75 parts by weight.

By blending the heparinoid substance in the emulsified composition of the present invention in the aforementioned ratio, the dispersion stability of iron oxide can be improved. As a result, it is possible to significantly reduce the iron oxide and other components in the emulsified composition, and also to effectively solve the color unevenness and the different performance effects of the components contained in the emulsified composition.

In the emulsified composition of the present invention, by further blending the heparinoid substance in the aforementioned ratio, the heparinoid substance can enhance the keratin moisture retention effect and anti-inflammatory effect (improving the effect of poor blood circulation). Furthermore, by using the aforementioned iron oxide in combination, the effect of the heparinoid substance and the effect of the iron oxide can be multiplied.

(c) Other ingredients blended in the emulsified composition

In the emulsified composition of the present invention, within a range that does not hinder the effects of the present invention, a target medicinal ingredient may be blended. The medicinal ingredients are not particularly limited, and it is preferable to use, for example, steroids, local anesthetics, anti-inflammatory agents, antiseptics, antipruritic agents, skin protectants, blood circulation promoting ingredients, vitamins, etc.

The emulsified composition of the present invention may contain surfactants (glyceryl monostearate, polyoxyethylene behenyl ether, etc.), stabilizers (ethylene diglyceride, etc.), as needed, within a range that does not hinder the effects of the present invention. Amine tetraethyl sodium, etc.), absorption promoting agents, sorbents, fillers, antioxidants, preservatives (methyl paraben, propyl paraben), emulsifiers, solubilizers, fungicides, Humectants, pH adjusters, fragrances, deodorants and dispersants, the aforementioned iron oxide, white pigments, and pigments other than bentonite.

Moreover, when the dispersibility of the composition containing clay minerals is not good, a method has been previously known to improve the dispersibility after blending a thickener. In contrast, the emulsified composition of the present invention does not necessarily incorporate a tackifier, and even if no tackifier is blended, the desired effect of the present invention can be obtained.

The pH of the emulsified composition of the present invention is not particularly limited, and can be appropriately set according to the purpose of use. For example, the pH value in the weakly acidic to neutral range can be cited. From the viewpoint of improving the feeling of use (the degree of adhesion to the skin, the degree of easy spreading, uneven color, and/or white residue), the pH value is 4 ~8 is better, pH 4~7 is better, and pH 4~6 is the best.

(2) Preparation method of emulsified composition

The emulsified composition of the present invention can be manufactured according to general emulsification methods in the relevant industry.

The types, contents, blending ratios, etc. of various components (essential components, optional components) used in the preparation method of the emulsified composition are described in the same manner as described above. In the preparation process of the emulsified composition, the components constituting the water phase or the components constituting the oil phase are mixed separately, heated to a temperature of about 50 to 90°C, and then a homogenizer, homomixer, or mixer, etc., is used to specify conditions It is better to mix. By this, it is possible to prepare a water-phase composition consisting of only the water phase and an oil composition consisting of only the oil phase. Next, after mixing the aqueous composition and the oily composition, emulsification is performed to prepare an emulsified composition. In addition, mixers such as the above-mentioned homogenizer, homomixer, and mixer can also be used for mixing.

At this time, if the emulsified composition of the present invention is a composition from a liquid state to a semi-solid state, the viscosity is not particularly limited. When the emulsified composition is liquid, the viscosity at room temperature is 1mPa. s~20,000mPa. S is better. When the emulsified composition is semi-solid, the viscosity at room temperature is 20,000 mPa. s~2,000,000mPa. S is better.

(3) Applicable objects of emulsified composition

The applicable object of the emulsified composition of the present invention is preferably external application, that is, application to skin (including scalp). For the purpose of applying the emulsified composition to the skin, if it is suitable for cosmetics and quasi-medicine for external use on the skin Drugs and external skin medicines are equivalent to the type of skin application, etc., and there are no special restrictions. For example, ointment, cream, paste, mousse, gel, suspension, emulsion, etc. are suitable for various desired external preparations.

When the emulsified composition of the present invention is applied to human skin, for example, the amount and frequency of the emulsified composition applied to the skin are not particularly limited. For example, depending on the type and concentration of the physiologically active substance contained, the age, gender, degree of symptoms, application type, degree of expectation, etc., an appropriate amount can be applied to the skin once to several times a day ( Particularly where symptoms occur) is better.

Although the emulsified composition of the present invention contains a large amount of clay minerals of 5 wt% or more, it has a good skin feeling. Specifically, it has good extensibility on the skin and is easy to adhere to the skin. In addition, it is not easy to cause color unevenness and white residue.

In addition, when the emulsified composition of the present invention contains heparinoid substances and iron oxide, the dispersion stability of clay minerals and powders (iron oxide, etc.) in the emulsified composition can be improved. As a result, the bias of the components contained in the emulsified composition of the present invention can be significantly reduced. As a result, the occurrence of color unevenness can be suppressed, and the effect of each component can be effectively resolved. This also improves the appearance of the emulsified composition. As a result, the quality of the emulsified composition containing iron oxide can be significantly improved.

(4) Ways to improve skin feeling

The method of the present invention for improving the feeling of use of the skin is to contain at least 5 weights In the emulsified composition of clay minerals, at least one mineral acid selected from the group consisting of hydrochloric acid, sulfuric acid, nitric acid, and phosphoric acid is coexisted. By blending related mineral acids, the emulsified composition is preferably adjusted to pH 4~8, pH 4~7 is better, and pH 4~6 is the best.

In this method, the types, contents, blending ratios, etc., of the components (essential components, optional components), etc., of the target emulsion composition are as described in (1). The record in (1) can be used here.

According to the method for improving the feeling of use of the skin according to the present invention, as shown in the following examples, compared with an emulsified composition prepared with an acid other than the above-mentioned acid (for example, an organic acid), it is possible to improve the extensibility (easy to stretch) on the skin. The degree of adhesion), and/or the degree of adhesion to the skin, and can provide an emulsified composition with good skin feeling. In addition, according to this method, it is possible to provide an emulsified composition that is less likely to produce color unevenness and/or white residue than the emulsified composition described above, and has a good feeling in use.

(5) Dispersion and stabilization method

The dispersion and stabilization method of the present invention is based on an emulsified composition containing at least 5% by weight of clay minerals, and at least one mineral acid, metal oxide, and the like are selected from the group consisting of hydrochloric acid, sulfuric acid, nitric acid and phosphoric acid. Heparin substances coexist and implement. By blending related mineral acids, the emulsified composition is preferably adjusted to pH 4~8, pH 4~7 is better, and pH 4~6 is the best.

In this method, the types, contents, blending ratios, etc., of the components (essential components, optional components), etc., of the target emulsion composition are as described in (1). The record in (1) can be used here.

The dispersion and stabilization method of the emulsified composition can be carried out according to the aforementioned emulsified composition preparation method.

According to the dispersion and stabilization method of the present invention, the dispersion stability of powders such as clay minerals and iron oxide in the emulsified composition can be improved as shown in the following examples. Therefore, according to the present invention, the bias of the components in the emulsified composition can be significantly reduced, the unequal effect performance can be effectively solved, and the appearance can also be improved. Therefore, it can be seen that the quality of the emulsified composition can be significantly improved. Furthermore, when produced as an emulsified composition, the emulsified state (emulsion-like) can be stably maintained over a long period of time.

[Example]

The present invention is specifically explained based on the embodiments, but the present invention is not limited to these embodiments.

Examples 1 to 2, Comparative Examples 1 to 4, and Reference Example 1

(1) Modulation method

According to the formula described in Table 1, the emulsified composition was prepared by the following method.

First, the clay minerals, powders, and water phase components described in Table 1 were individually weighed and mixed while heating at 80°C to uniformly dissolve the components in water to prepare an aqueous composition. Next, the oil phase components described in Table 1 were individually weighed and mixed while heating at 80°C to uniformly dissolve each component to prepare an oily composition. The oily composition and the aqueous composition prepared by mixing are mixed, and the emulsified composition is prepared after stirring. After cooling, when the temperature drops below 35°C, a pH regulator is added to adjust the pH to 5.

(2) Evaluation of usability

With respect to the obtained emulsified compositions (Examples 1 to 2, Comparative Examples 1 to 4, and Reference Example 1), ten evaluators were used as subjects, and the feeling of use was evaluated by the following method.

Approximately 0.2 g of each emulsified composition was applied to the wrist of the evaluator, and the feeling of use during application (degree of adhesion to the skin, degree of easy spreading, uneven color, white residue) was evaluated. The evaluation is based on the results of the average questionnaire of the Visual Analogue Scale (hereinafter referred to as "VAS") evaluated from 1 to 10 points based on the following criteria. The obtained result (average) is rounded to the second decimal place as the evaluation point .

The results are combined in Table 1. In addition, the evaluation points (relative) shown in Table 1 are relative values based on the actual evaluation points of Comparative Example 1 (100). That is, the actual evaluation points of Examples 1 to 2, Comparative Examples 2 to 4, and Reference Example 1 are divided by the actual evaluation points of Comparative Example 1, and then multiplied by 100 and expressed as a percentage (the first decimal place is rounded to the nearest whole number). ).

<The degree of adhesion to the skin>

1 point: poor adhesion to the skin during application

10 points: Excellent adhesion to the skin during application

<Easy to extend>

1: Poor degree of extension during coating

10 points: excellent extension during coating

<Uneven color>

1 point: uneven color after coating

10 points: no uneven color after coating

<White residue>

1 point: white residue after coating

10 points: no white residue after coating

As shown in Table Comparative Examples 3 and 4, there is no oil phase at all In the water-based composition, the clay minerals are precipitated, and a composition in which the clay minerals and powders are uniformly dispersed and stabilized cannot be obtained.

On the other hand, the emulsified composition containing clay minerals in a total amount of 5 wt% or more, the emulsified composition adjusted to pH 5 with mineral acid (hydrochloric acid, phosphoric acid) (Examples 1 and 2), did not find the precipitation of clay minerals. In addition, compared with the emulsified composition (Comparative Examples 1 and 2) whose pH was adjusted with lactic acid or citric acid, it was confirmed that the feeling of use was significantly improved in all evaluation items. In particular, it was found that the color was not all significantly improved (upgraded).

In addition, as shown in Reference Example 1, an emulsified composition with a clay mineral content of less than 5% by weight exhibits dispersion and stability, and has a feeling of use during application (degree of adhesion to skin, degree of easy spreading, uneven color , White residue) is no problem, it is good in any project.

Example 3 and Comparative Example 5

According to the formula described in Table 2, the emulsified composition was prepared by the same method as in Example 1. However, the difference is that the pH of the final emulsified composition is adjusted to 4 using a pH adjuster. With respect to the emulsified composition (pH 4) prepared in this way, the feeling of use on the skin was evaluated by the same method as in Example 1.

The results are shown in Table 2.

As shown in Table 2, by using hydrochloric acid instead of lactic acid as a pH adjuster, it was found that the feeling of use on the skin (the degree of adhesion to the skin, the degree of easy spreading, uneven color, and white residue) was significantly improved. . In particular, it was found that the color was not all significantly improved (upgraded).

Example 4 and Comparative Example 6

According to the formula described in Table 3, it was prepared by the same method as in Example 1. Emulsified composition. However, the difference is that the pH of the final emulsified composition is adjusted to 8 using a pH adjuster. With respect to the emulsified composition (pH 8) prepared in this way, the feeling of use on the skin was evaluated by the same method as in Example 1.

The results are shown in Table 3.

As shown in Table 3, by using hydrochloric acid instead as pH adjustment The lactic acid of the agent has been found to have a significant improvement in the feeling of use on the skin (the degree of adhesion to the skin, the degree of easy spreading, uneven color, and white residue). In particular, it was found that the color was not all significantly improved (upgraded).

Examples 5 to 6, Comparative Examples 7 and 8

According to the formula described in Table 4, the emulsified composition (pH 5) was prepared by the same method as in Example 1. With respect to the emulsified composition prepared in this way, the feeling of use on the skin was evaluated by the same method as in Example 1.

In all items of the feeling of use on the skin (degree of adhesion to skin, degree of easy spreading, uneven color, white residue), the emulsified composition of Examples 5 and 6 and the emulsified composition of Comparative Examples 7 and 8, respectively Compared with objects, they are all good. In addition, compared with Example 6, Example 5 is Easy to extend, uneven color and white residue items are more excellent.

Examples 7~9

According to the formula described in Table 5, the emulsified composition (pH 5.5) was prepared by the same method as in Example 1. With respect to the emulsified composition prepared in this way, the feeling of use on the skin was evaluated by the same method as in Example 1. In addition, the dispersion stability of the mineral clay and powder in the emulsified composition, and the coloration of the emulsified composition were evaluated according to the following method.

(1) Dispersion stability of clay minerals and powder

Take 20ml of the prepared emulsified composition and put it into a transparent ampoule (volume: 30ml), and place it at 25°C for 1 hour. According to the following standards, visually evaluate the dispersion of clay minerals and powders and their time-dependent properties Variety.

◎: Clay minerals and powders are uniformly dispersed in the emulsified composition in a stable state

○: Although clay minerals and powders are roughly dispersed in the emulsified composition, some unevenness of density appears on the wall surface

△: Clay minerals and powders are hardly dispersed in the emulsified composition, and precipitation occurs within a short period of time from the beginning, and a part of the supernatant becomes transparent

×: Clay minerals and powders are not dispersed, and precipitation occurs within a short period of time since the beginning of storage, and the supernatant becomes transparent

(2) Coloring properties of emulsified composition

The coloring properties (appearance) of the prepared emulsion composition were evaluated by visual observation.

◎: The color of the clay minerals and powders used is the same or almost the same color

○: The color of the clay mineral and powder used shows the same system color

△: The color is different from the clay mineral and powder used

×: A color completely different from the color of the clay mineral and powder used

The results related to dispersion stability and coloration are shown in Table 5.

From the results in Table 5, even if it is an emulsified composition containing clay minerals and a total of 5 wt% or more of powder, the dispersion stability and coloring properties are improved by blending iron oxide (ferric oxide) and heparinoid substances .

The feeling of use on the skin (the degree of adhesion to the skin, the degree of easy spreading, uneven color, and white residue) was as excellent as the aforementioned Example 1 in all items. The degree of easy extension on the skin is particularly excellent.

Formulation example 1~14

Tables 6 and 7 show the formulation examples of the emulsified composition of the present invention. Any of the emulsified compositions (formulation examples 1 to 14) also has an excellent usability (degree of adhesion to the skin, degree of easy spreading, uneven color, and white residue) compared to the emulsified composition of Comparative Example 1 described in Table 1.物). In addition, in addition to the formulation examples 1 to 14 described in Table 7, the formulations of the formulation examples 5 to 8 were prepared to contain 1g each of iron oxide yellow and iron oxide black and 0.3g of heparin-like substances.物(102.3g in total). Any of the emulsified compositions has excellent dispersion stability and coloring properties.

Claims (6)

An emulsified composition containing acids and heparinoid substances selected from the group consisting of hydrochloric acid, sulfuric acid, nitric acid and phosphoric acid, and 5-20% by weight of clay minerals. Such as the emulsified composition of claim 1, which further contains iron oxide. Such as the emulsified composition of claim 1 or 2, wherein the content of clay minerals is 5-15% by weight. For example, the emulsified composition of claim 1 or 2 has a pH of 4-7. Such as the emulsified composition of claim 1 or 2, which does not contain a thickener. Such as the emulsified composition of claim 1 or 2, which contains 0.01 to 3% by weight of heparinoid substances.