TWI678205B - 治療ｈｃｖ的方法 - Google Patents
治療ｈｃｖ的方法 Download PDFInfo
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- TWI678205B TWI678205B TW103109528A TW103109528A TWI678205B TW I678205 B TWI678205 B TW I678205B TW 103109528 A TW103109528 A TW 103109528A TW 103109528 A TW103109528 A TW 103109528A TW I678205 B TWI678205 B TW I678205B
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- weeks
- compound
- hcv
- pharmaceutically acceptable
- acceptable salt
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- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
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- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
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- Gastroenterology & Hepatology (AREA)
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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| US11484534B2 (en) | 2013-03-14 | 2022-11-01 | Abbvie Inc. | Methods for treating HCV |
| EP3318258B1 (en) | 2013-03-14 | 2020-05-13 | AbbVie Inc. | Combination of direct acting antiviral agents and ribavirin for treating hcv patients |
| CN105658219A (zh) * | 2013-10-25 | 2016-06-08 | 艾伯维公司 | 用于治疗hcv的方法 |
| US20150174194A1 (en) * | 2013-12-19 | 2015-06-25 | Abbvie Inc. | Methods for treating liver transplant recipients |
| CA2943054A1 (en) * | 2014-04-02 | 2015-10-08 | Abbvie Inc. | Methods for treating hcv |
| US20160375017A1 (en) | 2015-06-26 | 2016-12-29 | Abbvie Inc. | Solid Pharmaceutical Compositions for Treating HCV |
| EP3383662B1 (en) | 2016-01-08 | 2020-09-02 | Entrust Datacard Corporation | Card printing mechanism with card return path |
| JP7129703B2 (ja) | 2016-04-28 | 2022-09-02 | エモリー ユニバーシティー | アルキン含有ヌクレオチド及びヌクレオシド治療組成物並びにそれらに関連した使用 |
| MA46292A (fr) * | 2016-09-23 | 2019-07-31 | Abbvie Inc | Réglage de dose |
| CA2994496A1 (en) * | 2017-02-14 | 2018-08-14 | Abbvie Inc. | Methods for treating hcv |
| CA2981993A1 (en) * | 2017-08-02 | 2019-02-02 | Abbvie Inc. | Methods for treating hcv |
| CN108329332A (zh) * | 2018-03-16 | 2018-07-27 | 安徽华昌高科药业有限公司 | 一种制备Glecaprevir的方法 |
| CN112351799A (zh) * | 2018-04-10 | 2021-02-09 | 阿堤亚制药公司 | 具有硬化的hcv感染患者的治疗 |
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| US20120004196A1 (en) * | 2009-06-11 | 2012-01-05 | Abbott Labaoratories | Anti-Viral Compounds |
| US20120070416A1 (en) * | 2010-09-21 | 2012-03-22 | Enanta Pharmaceuticals, Inc. | Macrocyclic Proline Derived HCV Serine Protease Inhibitors |
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| JP2011522862A (ja) * | 2008-06-10 | 2011-08-04 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | テラプレビル（Ｔｅｌａｐｒｅｖｉｒ）投薬養生法 |
| US9394279B2 (en) | 2009-06-11 | 2016-07-19 | Abbvie Inc. | Anti-viral compounds |
| EP2853531A3 (en) * | 2009-06-11 | 2015-08-12 | AbbVie Bahamas Ltd. | Antiviral compounds |
| CN104023726A (zh) | 2011-10-21 | 2014-09-03 | 艾伯维公司 | 用于治疗hcv的一种或多种daa的联合治疗(例如，与abt-072或abt-333) |
| DE112012003510T5 (de) | 2011-10-21 | 2015-03-19 | Abbvie Inc. | Verfahren zur Behandlung von HCV umfassend mindestens zwei direkt wirkende antivirale Wirkstoffe, Ribavirin aber nicht Interferon |
| EP3318258B1 (en) | 2013-03-14 | 2020-05-13 | AbbVie Inc. | Combination of direct acting antiviral agents and ribavirin for treating hcv patients |
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| US20120004196A1 (en) * | 2009-06-11 | 2012-01-05 | Abbott Labaoratories | Anti-Viral Compounds |
| US20120070416A1 (en) * | 2010-09-21 | 2012-03-22 | Enanta Pharmaceuticals, Inc. | Macrocyclic Proline Derived HCV Serine Protease Inhibitors |
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