TWI635862B - 使用ｔｏｒ激酶抑制劑之癌症治療 - Google Patents

Info

Publication number

TWI635862B

TWI635862B TW102109151A TW102109151A TWI635862B TW I635862 B TWI635862 B TW I635862B TW 102109151 A TW102109151 A TW 102109151A TW 102109151 A TW102109151 A TW 102109151A TW I635862 B TWI635862 B TW I635862B

Authority

TW

Taiwan

Prior art keywords

substituted

unsubstituted

methyl

pyrazine

dihydropyrazino

Prior art date

2012-03-15

Links

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• 206010028980 Neoplasm Diseases 0.000 title claims description 67
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• 208000003721 Triple Negative Breast Neoplasms Diseases 0.000 claims abstract description 68
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• 238000000034 method Methods 0.000 claims abstract description 38
• -1 2-methyl-6- (1H-1,2,4-triazol-3-yl) pyridin-3-yl Chemical group 0.000 claims description 393
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• GMYLVKUGJMYTFB-UHFFFAOYSA-N 5-ethyl-3-[2-methyl-6-(1h-1,2,4-triazol-5-yl)pyridin-3-yl]-7,8-dihydropyrazino[2,3-b]pyrazin-6-one Chemical compound N1=C2N(CC)C(=O)CNC2=NC=C1C(C(=N1)C)=CC=C1C1=NN=CN1 GMYLVKUGJMYTFB-UHFFFAOYSA-N 0.000 claims description 13
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