TWI616528B - 應用人脂肪衍生的幹細胞增殖血清來源的c型肝炎病毒及其用途 - Google Patents
應用人脂肪衍生的幹細胞增殖血清來源的c型肝炎病毒及其用途 Download PDFInfo
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- TWI616528B TWI616528B TW104115953A TW104115953A TWI616528B TW I616528 B TWI616528 B TW I616528B TW 104115953 A TW104115953 A TW 104115953A TW 104115953 A TW104115953 A TW 104115953A TW I616528 B TWI616528 B TW I616528B
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
- C12N5/0667—Adipose-derived stem cells [ADSC]; Adipose stromal stem cells
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
- C12Q1/706—Specific hybridization probes for hepatitis
- C12Q1/707—Specific hybridization probes for hepatitis non-A, non-B Hepatitis, excluding hepatitis D
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
- G01N33/5073—Stem cells
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/576—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis
- G01N33/5767—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis non-A, non-B hepatitis
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/70—Non-animal cells
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
- C12N2770/24251—Methods of production or purification of viral material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/136—Screening for pharmacological compounds
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
- G01N2333/08—RNA viruses
- G01N2333/18—Togaviridae; Flaviviridae
- G01N2333/183—Flaviviridae, e.g. pestivirus, mucosal disease virus, bovine viral diarrhoea virus, classical swine fever virus (hog cholera virus) or border disease virus
- G01N2333/186—Hepatitis C; Hepatitis NANB
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- Physics & Mathematics (AREA)
- Communicable Diseases (AREA)
- General Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- Virology (AREA)
- Food Science & Technology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Developmental Biology & Embryology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Rheumatology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ??PCT/CN2015/070243 | 2015-01-07 | ||
| PCT/CN2015/070243 WO2016109947A1 (en) | 2015-01-07 | 2015-01-07 | Employing human adipose-derived stem cells to propagate serum-derived hepatitis c virus and use thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TW201625786A TW201625786A (zh) | 2016-07-16 |
| TWI616528B true TWI616528B (zh) | 2018-03-01 |
Family
ID=56355408
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW104115953A TWI616528B (zh) | 2015-01-07 | 2015-05-19 | 應用人脂肪衍生的幹細胞增殖血清來源的c型肝炎病毒及其用途 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US10273461B2 (enExample) |
| EP (1) | EP3242932A4 (enExample) |
| JP (1) | JP6670322B2 (enExample) |
| KR (1) | KR20170101998A (enExample) |
| CN (1) | CN107208060B (enExample) |
| AU (1) | AU2015376561A1 (enExample) |
| CA (1) | CA2973119A1 (enExample) |
| HK (1) | HK1246824A1 (enExample) |
| TW (1) | TWI616528B (enExample) |
| WO (1) | WO2016109947A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL272145A (en) * | 2020-01-20 | 2021-07-29 | Stem Cell Medicine Ltd | Cosmetic preparations with protein concentrate from a conditioned growth medium of stem cells from adipose tissue |
| IL278473A (en) | 2020-11-03 | 2022-06-01 | Yeda Res & Dev | Methods for diagnosing and determining treatment in multiple myeloma |
| CN114686517A (zh) * | 2020-12-25 | 2022-07-01 | 中国医学科学院病原生物学研究所 | 一种hcv四受体转基因合并stat1敲除小鼠的制备方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5786207A (en) | 1997-05-28 | 1998-07-28 | University Of Pittsburgh | Tissue dissociating system and method |
| CN1166773C (zh) | 1997-12-02 | 2004-09-15 | 泽恩比奥公司 | 分离的人脂肪组织衍生的基质细胞 |
| US6777231B1 (en) | 1999-03-10 | 2004-08-17 | The Regents Of The University Of California | Adipose-derived stem cells and lattices |
| US20050076396A1 (en) | 1999-03-10 | 2005-04-07 | Katz Adam J. | Adipose-derived stem cells and lattices |
| JP2009153383A (ja) * | 2006-04-03 | 2009-07-16 | Eci Inc | 成熟肝細胞様細胞の製造方法 |
| KR101224504B1 (ko) * | 2010-10-01 | 2013-01-22 | 가톨릭대학교 산학협력단 | 크립토탄신온의 신규 용도 |
| GB201119335D0 (en) * | 2011-11-09 | 2011-12-21 | Univ Leuven Kath | Hepatitis virus infectable stem cells |
| US20140179775A1 (en) * | 2012-02-29 | 2014-06-26 | Mead Johnson Nutrition Company | Neurogenesis screening method and uses thereof |
| US9402710B2 (en) * | 2012-07-16 | 2016-08-02 | The Board Of Trustees For The Leland Stanford Junior University | Macroporous 3-D scaffolds for tissue engineering |
-
2015
- 2015-01-07 EP EP15876456.3A patent/EP3242932A4/en not_active Withdrawn
- 2015-01-07 JP JP2017554627A patent/JP6670322B2/ja active Active
- 2015-01-07 US US15/541,913 patent/US10273461B2/en active Active
- 2015-01-07 CA CA2973119A patent/CA2973119A1/en not_active Abandoned
- 2015-01-07 AU AU2015376561A patent/AU2015376561A1/en not_active Abandoned
- 2015-01-07 HK HK18106252.0A patent/HK1246824A1/zh unknown
- 2015-01-07 WO PCT/CN2015/070243 patent/WO2016109947A1/en not_active Ceased
- 2015-01-07 CN CN201580072851.XA patent/CN107208060B/zh active Active
- 2015-01-07 KR KR1020177022015A patent/KR20170101998A/ko not_active Withdrawn
- 2015-05-19 TW TW104115953A patent/TWI616528B/zh active
Non-Patent Citations (5)
| Title |
|---|
| 內科學誌,20,309-319 * |
| 謝佩真等 (2009) C型肝炎病毒基因分型及其臨床重要性 * |
| 謝佩真等 (2009) C型肝炎病毒基因分型及其臨床重要性。內科學誌,20,309-319。 |
| 黃薪睿 (2013) 丙型肝炎病毒可感染人類脂肪幹細胞並做有效率的複製 高雄醫學大學碩士論文 * |
| 黃薪睿 (2013) 丙型肝炎病毒可感染人類脂肪幹細胞並做有效率的複製 高雄醫學大學碩士論文。 |
Also Published As
| Publication number | Publication date |
|---|---|
| EP3242932A4 (en) | 2018-05-30 |
| EP3242932A1 (en) | 2017-11-15 |
| CA2973119A1 (en) | 2016-07-14 |
| AU2015376561A1 (en) | 2017-07-27 |
| JP2018501820A (ja) | 2018-01-25 |
| KR20170101998A (ko) | 2017-09-06 |
| US10273461B2 (en) | 2019-04-30 |
| HK1246824A1 (zh) | 2018-09-14 |
| JP6670322B2 (ja) | 2020-03-18 |
| WO2016109947A1 (en) | 2016-07-14 |
| CN107208060A (zh) | 2017-09-26 |
| TW201625786A (zh) | 2016-07-16 |
| CN107208060B (zh) | 2021-06-18 |
| US20180023058A1 (en) | 2018-01-25 |
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