TWI577384B - 新穎利鈉尿胜肽受體-b(npr-b)同效劑 - Google Patents
新穎利鈉尿胜肽受體-b(npr-b)同效劑 Download PDFInfo
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- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/58—Atrial natriuretic factor complex; Atriopeptin; Atrial natriuretic peptide [ANP]; Cardionatrin; Cardiodilatin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/02—Linear peptides containing at least one abnormal peptide link
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
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- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
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- Proteomics, Peptides & Aminoacids (AREA)
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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| SI2510942T1 (sl) | 2005-04-07 | 2016-01-29 | Cardiorentis Ag | Uporaba natriuretskega peptida za zdravljenje srčne odpovedi |
| WO2008014733A1 (de) * | 2006-08-02 | 2008-02-07 | Johannes Gutenberg-Universität Mainz | Arzneimittel gegen lct-vergiftungen |
| BR112012006579A2 (pt) * | 2009-09-25 | 2016-11-22 | Alcon Res Ltd | agonistas de npr-b. |
| AR078446A1 (es) | 2009-12-18 | 2011-11-09 | Alcon Res Ltd | Agonistas de npr-b. uso. |
| US20150045301A1 (en) * | 2011-12-16 | 2015-02-12 | Kalos Therapeutics, Inc. | Methods and uses of anp (atrial natriuretic peptide), bnp (brain natriuretic peptide) and cnp (c-type natriuretic peptide)-related peptides and derivatives thereof for treatment of retinal disorders and diseases |
| WO2014115033A2 (en) * | 2013-01-25 | 2014-07-31 | Cardiorentis Ltd. | Methods of treating cardiovascular indications |
| CN109563144B (zh) | 2016-06-01 | 2023-03-28 | 雅斯娜 | 化合物 |
| JP2020505476A (ja) * | 2017-02-01 | 2020-02-20 | シャイアー ヒューマン ジェネティック セラピーズ インコーポレイテッド | 眼科障害の治療のための化合物および組成物 |
| US20210121534A1 (en) * | 2018-06-19 | 2021-04-29 | Cella Therapeutics, Llc | Sustained-release drug delivery systems comprising an intraocular pressure lowering agent, a cnp compound, an npr-b compound, a tie-2 agonist, or neurotrophic agent for use for treating glaucoma or ocular hypertension |
| CA3120196A1 (en) | 2018-11-16 | 2020-05-22 | Arcus Biosciences, Inc. | Inhibitors of arg1 and/or arg2 |
| KR20230024352A (ko) * | 2020-06-12 | 2023-02-20 | 파마인 코포레이션 | C형 나트륨이뇨 펩타이드 및 이의 급성 폐 손상의 치료에서의 방법 |
| KR102677730B1 (ko) * | 2023-03-27 | 2024-06-27 | 나인바이오팜 주식회사 | 지방 분해 효능을 갖는 펩타이드 및 이의 용도 |
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|---|---|---|---|---|
| US4757048A (en) * | 1985-11-05 | 1988-07-12 | Biotechnology Research Associates J.V. | Synthetic analogs of atrial natriuretic peptides |
| US20080153747A1 (en) * | 2004-07-15 | 2008-06-26 | The University Of Queensland | Proteinaceous compounds and uses therefor |
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| AU2927889A (en) * | 1987-12-24 | 1989-07-19 | California Biotechnology, Inc. | Linear analogs of atrial natriuretic peptides |
| AU4211989A (en) * | 1988-08-18 | 1990-03-23 | California Biotechnology, Inc. | Atrial natriuretic peptide clearance inhibitors |
| EP1118329A4 (en) | 1998-09-28 | 2004-12-15 | Santen Pharmaceutical Co Ltd | LACRYMAL SECRETION PROMOTERS OR OPHTHALMOLOGICAL DROPS CONTAINING NATRIURETIC PEPTIDES AS ACTIVE INGREDIENTS FOR TREATING KERATOCONJUNCTIVITY |
| US20040266673A1 (en) * | 2002-07-31 | 2004-12-30 | Peter Bakis | Long lasting natriuretic peptide derivatives |
| US6025198A (en) | 1999-06-25 | 2000-02-15 | Isis Pharmaceuticals Inc. | Antisense modulation of Ship-2 expression |
| US6436703B1 (en) * | 2000-03-31 | 2002-08-20 | Hyseq, Inc. | Nucleic acids and polypeptides |
| IL142118A0 (en) * | 2001-03-20 | 2002-03-10 | Prochon Biotech Ltd | Method and composition for treatment of skeletal dysplasias |
| TWI231759B (en) | 2001-06-27 | 2005-05-01 | Alcon Inc | Olopatadine formulations for topical administration |
| US7648962B2 (en) | 2002-11-26 | 2010-01-19 | Biocon Limited | Natriuretic compounds, conjugates, and uses thereof |
| US7297709B2 (en) | 2003-05-22 | 2007-11-20 | Abbott Laboratories | Indazole, benzisoxazole, and benzisothiazole kinase inhibitors |
| TW200640443A (en) | 2005-02-23 | 2006-12-01 | Alcon Inc | Methods for treating ocular angiogenesis, retinal edema, retinal ischemia, and diabetic retinopathy using selective RTK inhibitors |
| US20090035287A1 (en) * | 2005-09-26 | 2009-02-05 | Zurit Levine | Atrial natriuretic peptide (anp) splice variants and methods of using same |
| EP1951277A2 (en) * | 2005-10-14 | 2008-08-06 | Biorexis Pharmaceutical Corporation | Natriuretic peptide modified transferrin fusion proteins |
| KR101434612B1 (ko) | 2006-03-30 | 2014-08-26 | 팔라틴 테크놀로지스 인코포레이티드 | 사이클릭 나트륨 이뇨 펩타이드 구조물 |
| EP2004633A4 (en) * | 2006-03-30 | 2009-08-26 | Palatin Technologies Inc | LINEAR NATRIURETIC PEPTIDE CONSTRUCTS |
| AR069409A1 (es) * | 2007-11-21 | 2010-01-20 | Biomarin Pharm Inc | Variantes de peptidos natriureticos de tipo c |
| BR112012006579A2 (pt) * | 2009-09-25 | 2016-11-22 | Alcon Res Ltd | agonistas de npr-b. |
| WO2011038066A2 (en) | 2009-09-25 | 2011-03-31 | Alcon Research, Ltd. | Novel npr-b agonists |
| AR078446A1 (es) | 2009-12-18 | 2011-11-09 | Alcon Res Ltd | Agonistas de npr-b. uso. |
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- 2010-09-23 RU RU2015124607A patent/RU2636738C2/ru active
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4757048A (en) * | 1985-11-05 | 1988-07-12 | Biotechnology Research Associates J.V. | Synthetic analogs of atrial natriuretic peptides |
| US20080153747A1 (en) * | 2004-07-15 | 2008-06-26 | The University Of Queensland | Proteinaceous compounds and uses therefor |
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