TWI531650B - 用於預防及治療非酒精性脂肪肝疾病的腺病毒ad36 e4orf1蛋白 - Google Patents

用於預防及治療非酒精性脂肪肝疾病的腺病毒ad36 e4orf1蛋白 Download PDF

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Publication number
TWI531650B
TWI531650B TW100124173A TW100124173A TWI531650B TW I531650 B TWI531650 B TW I531650B TW 100124173 A TW100124173 A TW 100124173A TW 100124173 A TW100124173 A TW 100124173A TW I531650 B TWI531650 B TW I531650B
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TW
Taiwan
Prior art keywords
protein
adenovirus
nucleic acid
liver
seq
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TW100124173A
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English (en)
Chinese (zh)
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TW201217529A (en
Inventor
尼克西爾 度朗哈
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路易斯安那州立大學暨農業機械學院管委會
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/162Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/10011Adenoviridae
    • C12N2710/10311Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10333Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
TW100124173A 2010-07-08 2011-07-08 用於預防及治療非酒精性脂肪肝疾病的腺病毒ad36 e4orf1蛋白 TWI531650B (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US36244310P 2010-07-08 2010-07-08

Publications (2)

Publication Number Publication Date
TW201217529A TW201217529A (en) 2012-05-01
TWI531650B true TWI531650B (zh) 2016-05-01

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TW100124173A TWI531650B (zh) 2010-07-08 2011-07-08 用於預防及治療非酒精性脂肪肝疾病的腺病毒ad36 e4orf1蛋白

Country Status (11)

Country Link
US (2) US8951980B2 (enExample)
EP (1) EP2590665B1 (enExample)
JP (1) JP5965397B2 (enExample)
KR (1) KR101831638B1 (enExample)
CN (1) CN103052397B (enExample)
AU (1) AU2011274537B9 (enExample)
CA (1) CA2803787C (enExample)
ES (1) ES2550962T3 (enExample)
NZ (1) NZ606236A (enExample)
TW (1) TWI531650B (enExample)
WO (1) WO2012006512A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2618374T3 (es) 2012-10-17 2017-06-21 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Composiciones y métodos para mejorar la absorción de glucosa
US9354963B2 (en) * 2014-02-26 2016-05-31 Microsoft Technology Licensing, Llc Service metric analysis from structured logging schema of usage data
WO2015164312A1 (en) 2014-04-23 2015-10-29 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College SMALL MOLECULE ANALOGS OF E4orf1
GB201910299D0 (en) * 2019-07-18 2019-09-04 Aouadi Myriam Medical uses, methods and uses

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1626280B1 (en) * 2004-08-12 2007-02-14 Roche Diagnostics GmbH Method for diagnosing liver fibrosis
US20060045919A1 (en) 2004-08-27 2006-03-02 Samueli Institute Homeopathic compositions and methods for the treatment of cancer
JP2008105945A (ja) * 2005-02-07 2008-05-08 Ajinomoto Co Inc アディポネクチンの分泌促進又は誘導作用を有するアシルアミド化合物
EP1954131B1 (en) * 2005-11-30 2014-04-02 Board of Supervisors of Louisiana State University and Agricultural and Mechanical College Adenovirus 36 e4 orf 1 gene and protein and their uses
AU2006342053A1 (en) * 2005-12-27 2007-10-25 Obetech, Llc Adipogenic adenoviruses as a biomarker for disease
JP2008273938A (ja) * 2007-03-30 2008-11-13 Shiseido Co Ltd アディポネクチン産生促進剤

Also Published As

Publication number Publication date
ES2550962T3 (es) 2015-11-13
AU2011274537B2 (en) 2016-12-15
CN103052397B (zh) 2017-09-19
CN103052397A (zh) 2013-04-17
EP2590665A1 (en) 2013-05-15
CA2803787C (en) 2018-12-04
CA2803787A1 (en) 2012-01-12
HK1185261A1 (en) 2014-02-14
KR20130100262A (ko) 2013-09-10
AU2011274537A1 (en) 2013-02-14
JP5965397B2 (ja) 2016-08-03
EP2590665B1 (en) 2015-09-16
US20170340699A1 (en) 2017-11-30
NZ606236A (en) 2014-09-26
US20120027845A1 (en) 2012-02-02
AU2011274537B9 (en) 2017-02-23
US8951980B2 (en) 2015-02-10
JP2013531681A (ja) 2013-08-08
WO2012006512A1 (en) 2012-01-12
KR101831638B1 (ko) 2018-02-23
TW201217529A (en) 2012-05-01

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