TWI468679B - 決定樣本中之待測物濃度的方法及使用該方法的手持式測量裝置和生物感測器系統 - Google Patents
決定樣本中之待測物濃度的方法及使用該方法的手持式測量裝置和生物感測器系統 Download PDFInfo
- Publication number
- TWI468679B TWI468679B TW97143312A TW97143312A TWI468679B TW I468679 B TWI468679 B TW I468679B TW 97143312 A TW97143312 A TW 97143312A TW 97143312 A TW97143312 A TW 97143312A TW I468679 B TWI468679 B TW I468679B
- Authority
- TW
- Taiwan
- Prior art keywords
- seconds
- sample
- pulse
- excitation pulse
- current
- Prior art date
Links
- 239000012491 analyte Substances 0.000 title claims description 57
- 238000000034 method Methods 0.000 title claims description 48
- 238000005259 measurement Methods 0.000 title description 19
- 230000005284 excitation Effects 0.000 claims description 66
- 238000009792 diffusion process Methods 0.000 claims description 22
- 230000004044 response Effects 0.000 claims description 17
- 238000012360 testing method Methods 0.000 claims description 17
- 230000004888 barrier function Effects 0.000 claims description 16
- 239000013060 biological fluid Substances 0.000 claims description 15
- 238000004891 communication Methods 0.000 claims description 14
- 239000000126 substance Substances 0.000 claims description 11
- 230000001052 transient effect Effects 0.000 claims description 10
- 238000012545 processing Methods 0.000 claims description 5
- 230000000977 initiatory effect Effects 0.000 claims 1
- 239000000523 sample Substances 0.000 description 78
- 210000004369 blood Anatomy 0.000 description 32
- 239000008280 blood Substances 0.000 description 32
- 241000894007 species Species 0.000 description 25
- 238000004458 analytical method Methods 0.000 description 20
- 239000004020 conductor Substances 0.000 description 16
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 15
- 239000008103 glucose Substances 0.000 description 15
- 239000003153 chemical reaction reagent Substances 0.000 description 10
- 230000003287 optical effect Effects 0.000 description 10
- 230000008859 change Effects 0.000 description 8
- 230000000694 effects Effects 0.000 description 8
- 238000005534 hematocrit Methods 0.000 description 8
- 108090000790 Enzymes Proteins 0.000 description 7
- 102000004190 Enzymes Human genes 0.000 description 7
- 229940088598 enzyme Drugs 0.000 description 7
- 239000007788 liquid Substances 0.000 description 6
- 238000006479 redox reaction Methods 0.000 description 5
- BPYKTIZUTYGOLE-IFADSCNNSA-N Bilirubin Chemical compound N1C(=O)C(C)=C(C=C)\C1=C\C1=C(C)C(CCC(O)=O)=C(CC2=C(C(C)=C(\C=C/3C(=C(C=C)C(=O)N\3)C)N2)CCC(O)=O)N1 BPYKTIZUTYGOLE-IFADSCNNSA-N 0.000 description 4
- 108090000854 Oxidoreductases Proteins 0.000 description 4
- 102000004316 Oxidoreductases Human genes 0.000 description 4
- 238000004082 amperometric method Methods 0.000 description 4
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 4
- 238000000840 electrochemical analysis Methods 0.000 description 4
- 210000003743 erythrocyte Anatomy 0.000 description 4
- 230000003647 oxidation Effects 0.000 description 4
- 238000007254 oxidation reaction Methods 0.000 description 4
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 3
- 230000006870 function Effects 0.000 description 3
- 238000000691 measurement method Methods 0.000 description 3
- 229920000642 polymer Polymers 0.000 description 3
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 2
- JVTAAEKCZFNVCJ-UHFFFAOYSA-M Lactate Chemical compound CC(O)C([O-])=O JVTAAEKCZFNVCJ-UHFFFAOYSA-M 0.000 description 2
- LEHOTFFKMJEONL-UHFFFAOYSA-N Uric Acid Chemical compound N1C(=O)NC(=O)C2=C1NC(=O)N2 LEHOTFFKMJEONL-UHFFFAOYSA-N 0.000 description 2
- TVWHNULVHGKJHS-UHFFFAOYSA-N Uric acid Natural products N1C(=O)NC(=O)C2NC(=O)NC21 TVWHNULVHGKJHS-UHFFFAOYSA-N 0.000 description 2
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 2
- 229910052799 carbon Inorganic materials 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 2
- 235000012000 cholesterol Nutrition 0.000 description 2
- 238000007796 conventional method Methods 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 238000002848 electrochemical method Methods 0.000 description 2
- YAGKRVSRTSUGEY-UHFFFAOYSA-N ferricyanide Chemical compound [Fe+3].N#[C-].N#[C-].N#[C-].N#[C-].N#[C-].N#[C-] YAGKRVSRTSUGEY-UHFFFAOYSA-N 0.000 description 2
- 239000003292 glue Substances 0.000 description 2
- 210000002977 intracellular fluid Anatomy 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 239000002184 metal Substances 0.000 description 2
- 238000001208 nuclear magnetic resonance pulse sequence Methods 0.000 description 2
- 238000006722 reduction reaction Methods 0.000 description 2
- 230000000630 rising effect Effects 0.000 description 2
- 229940116269 uric acid Drugs 0.000 description 2
- 241001522296 Erithacus rubecula Species 0.000 description 1
- 108010015776 Glucose oxidase Proteins 0.000 description 1
- 239000004366 Glucose oxidase Substances 0.000 description 1
- COLNVLDHVKWLRT-QMMMGPOBSA-N L-phenylalanine Chemical compound OC(=O)[C@@H](N)CC1=CC=CC=C1 COLNVLDHVKWLRT-QMMMGPOBSA-N 0.000 description 1
- 230000005856 abnormality Effects 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000011230 binding agent Substances 0.000 description 1
- 239000007795 chemical reaction product Substances 0.000 description 1
- 238000012937 correction Methods 0.000 description 1
- 230000002596 correlated effect Effects 0.000 description 1
- 230000000875 corresponding effect Effects 0.000 description 1
- 238000003869 coulometry Methods 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 206010012601 diabetes mellitus Diseases 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 230000037213 diet Effects 0.000 description 1
- 235000005911 diet Nutrition 0.000 description 1
- 235000014113 dietary fatty acids Nutrition 0.000 description 1
- 239000003085 diluting agent Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 230000005279 excitation period Effects 0.000 description 1
- 210000003722 extracellular fluid Anatomy 0.000 description 1
- 229930195729 fatty acid Natural products 0.000 description 1
- 239000000194 fatty acid Substances 0.000 description 1
- 150000004665 fatty acids Chemical class 0.000 description 1
- 239000000706 filtrate Substances 0.000 description 1
- 229940116332 glucose oxidase Drugs 0.000 description 1
- 235000019420 glucose oxidase Nutrition 0.000 description 1
- 150000004677 hydrates Chemical class 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 150000002576 ketones Chemical class 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- COLNVLDHVKWLRT-UHFFFAOYSA-N phenylalanine Natural products OC(=O)C(N)CC1=CC=CC=C1 COLNVLDHVKWLRT-UHFFFAOYSA-N 0.000 description 1
- 210000002381 plasma Anatomy 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
- 230000003334 potential effect Effects 0.000 description 1
- 238000004313 potentiometry Methods 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 239000000376 reactant Substances 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 239000013074 reference sample Substances 0.000 description 1
- 210000003296 saliva Anatomy 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 239000013049 sediment Substances 0.000 description 1
- 239000004065 semiconductor Substances 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 150000003626 triacylglycerols Chemical class 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
- 238000013022 venting Methods 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/28—Electrolytic cell components
- G01N27/30—Electrodes, e.g. test electrodes; Half-cells
- G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/28—Electrolytic cell components
- G01N27/30—Electrodes, e.g. test electrodes; Half-cells
- G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
- G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
- G01N27/3273—Devices therefor, e.g. test element readers, circuitry
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pathology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Electrochemistry (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1272907P | 2007-12-10 | 2007-12-10 | |
| PCT/US2008/080865 WO2009075951A1 (en) | 2007-12-10 | 2008-10-23 | Rapid-read gated amperometry |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TW200925592A TW200925592A (en) | 2009-06-16 |
| TWI468679B true TWI468679B (zh) | 2015-01-11 |
Family
ID=40120419
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW97143312A TWI468679B (zh) | 2007-12-10 | 2008-11-10 | 決定樣本中之待測物濃度的方法及使用該方法的手持式測量裝置和生物感測器系統 |
Country Status (10)
| Country | Link |
|---|---|
| US (5) | US8147674B2 (https=) |
| EP (3) | EP3395954B1 (https=) |
| JP (1) | JP5455924B2 (https=) |
| CN (2) | CN101896619B (https=) |
| BR (1) | BRPI0820718A2 (https=) |
| CA (1) | CA2707300C (https=) |
| MX (1) | MX2010006393A (https=) |
| RU (1) | RU2491549C2 (https=) |
| TW (1) | TWI468679B (https=) |
| WO (1) | WO2009075951A1 (https=) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1914331A (zh) | 2004-02-06 | 2007-02-14 | 拜尔健康护理有限责任公司 | 作为生物传感器的内部参照的可氧化种类和使用方法 |
| WO2007013915A1 (en) * | 2005-07-20 | 2007-02-01 | Bayer Healthcare Llc | Gated amperometry |
| EP3543348B1 (en) | 2006-09-22 | 2020-11-18 | Ascensia Diabetes Care Holdings AG | Biosensor system having enhanced stability and hematocrit performance |
| EP3395954B1 (en) * | 2007-12-10 | 2020-07-01 | Ascensia Diabetes Care Holdings AG | Rapid-read gated amperometry |
| WO2009076302A1 (en) | 2007-12-10 | 2009-06-18 | Bayer Healthcare Llc | Control markers for auto-detection of control solution and methods of use |
| JP5773883B2 (ja) | 2008-12-08 | 2015-09-02 | バイエル・ヘルスケア・エルエルシーＢａｙｅｒ ＨｅａｌｔｈＣａｒｅＬＬＣ | バイオセンサのための低全塩試薬組成物およびシステム |
| US9233788B2 (en) | 2010-01-22 | 2016-01-12 | Bayer Healthcare Llc | Biosensor desiccant system having enhanced measurement performance |
| TWI565943B (zh) | 2011-07-22 | 2017-01-11 | 拜耳保健公司 | 具有增進測量性能之生物感測器乾燥劑系統 |
| US9816957B2 (en) | 2012-12-12 | 2017-11-14 | Panasonic Healthcare Holdings Co., Ltd. | Blood component measuring device, method for measuring blood component, and bio-sensor |
| EP3388823B1 (en) | 2013-03-15 | 2024-07-10 | Roche Diabetes Care GmbH | Method of scaling data used to construct biosensor algorithms |
| WO2014140172A1 (en) | 2013-03-15 | 2014-09-18 | Roche Diagnostics Gmbh | Methods of failsafing electrochemical measurements of an analyte as well as devices, apparatuses and systems incorporating the same |
| WO2014140173A1 (en) | 2013-03-15 | 2014-09-18 | Roche Diagnostics Gmbh | Descriptor-based methods of electrochemically measuring an analyte as well as devices, apparatuses and systems incoporating the same |
| JP6356708B2 (ja) | 2013-03-15 | 2018-07-11 | エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ | パルスｄｃブロックを有するテスト・シーケンスで分析物を電気化学的に測定する方法およびデバイス、装置とそれらを組み込むシステム |
| KR101736651B1 (ko) | 2013-03-15 | 2017-05-16 | 에프. 호프만-라 로슈 아게 | 전기화학적 분석물질 측정에서 회복 펄스로부터 정보를 이용하는 방법들 뿐만 아니라 이를 통합한 기기들, 장치들 및 시스템들 |
| EP2972269B1 (en) | 2013-03-15 | 2018-07-11 | Roche Diabetes Care GmbH | Methods of detecting high antioxidant levels during electrochemical measurements and failsafing an analyte concentration therefrom |
| US9738916B2 (en) | 2013-07-08 | 2017-08-22 | Panasonic Healthcare Holdings Co., Ltd. | Blood component measurement device and blood component measurement method |
| KR101666978B1 (ko) | 2014-09-17 | 2016-10-24 | 주식회사 아이센스 | 생체시료 내 분석대상물질의 농도측정방법 및 측정장치 |
| EP3485265B1 (en) | 2016-07-12 | 2025-03-12 | Ascensia Diabetes Care Holdings AG | Method for electrochemical analysis by use of alternating output signals from two electrodes |
| JP7074753B2 (ja) * | 2016-12-05 | 2022-05-24 | アセンシア・ダイアベティス・ケア・ホールディングス・アーゲー | リスク因子モニタリング |
| CN110954687B (zh) * | 2019-11-18 | 2022-06-07 | 深圳微点生物技术股份有限公司 | 一种用于凝血检测的方法与设备 |
| WO2022130229A1 (en) * | 2020-12-17 | 2022-06-23 | S2G Technologies S.R.L. Startup Costituita Ai Sensi Dell'art. 4, Comma10-Bis D.L. 3/2015 Convertito Con Legge 33/2015 | Device for analysing a biological fluid |
| US12141240B2 (en) * | 2021-01-20 | 2024-11-12 | Rutgers, The State University Of New Jersey | Method of calibration using master calibration function |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6413411B1 (en) * | 1995-02-09 | 2002-07-02 | Tall Oak Ventures | Method and apparatus for amperometric diagnostic analysis |
| TW200630070A (en) * | 2004-10-21 | 2006-09-01 | Bayer Healthcare Llc | Method of determining the concentration of an analyte in a body fluid and system therefor |
| TW200716965A (en) * | 2005-05-25 | 2007-05-01 | Bayer Healthcare Llc | Methods of using raman spectral information in determining analyte concentrations |
Family Cites Families (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4994167A (en) | 1986-04-15 | 1991-02-19 | Markwell Medical Institute, Inc. | Biological fluid measuring device |
| US4897162A (en) | 1986-11-14 | 1990-01-30 | The Cleveland Clinic Foundation | Pulse voltammetry |
| EP0359831B2 (en) | 1988-03-31 | 2007-06-20 | Matsushita Electric Industrial Co., Ltd. | Biosensor and process for its production |
| US5131999A (en) | 1990-01-16 | 1992-07-21 | The National University Of Singapore | Voltammetric detector for flow analysis |
| EP1357481A3 (en) | 1991-03-07 | 2005-04-27 | Masimo Corporation | Signal processing apparatus and method |
| US5756362A (en) | 1993-10-12 | 1998-05-26 | Cornell Research Foundation, Inc. | Liposome-enhanced immunoaggregation assay and test device |
| IE72524B1 (en) | 1994-11-04 | 1997-04-23 | Elan Med Tech | Analyte-controlled liquid delivery device and analyte monitor |
| US5620579A (en) | 1995-05-05 | 1997-04-15 | Bayer Corporation | Apparatus for reduction of bias in amperometric sensors |
| AUPN661995A0 (en) | 1995-11-16 | 1995-12-07 | Memtec America Corporation | Electrochemical cell 2 |
| US5708247A (en) | 1996-02-14 | 1998-01-13 | Selfcare, Inc. | Disposable glucose test strips, and methods and compositions for making same |
| CA2225334A1 (en) | 1996-04-22 | 1997-10-30 | Imra Japan Kabushikikaisha | Co gas sensor and method of measuring the concentration of co gas |
| US6391558B1 (en) * | 1997-03-18 | 2002-05-21 | Andcare, Inc. | Electrochemical detection of nucleic acid sequences |
| AU8031898A (en) | 1997-06-16 | 1999-01-04 | Elan Medical Technologies Limited | Methods of calibrating and testing a sensor for (in vivo) measurement of an analyte and devices for use in such methods |
| WO1999060391A1 (fr) | 1998-05-20 | 1999-11-25 | Arkray, Inc. | Procede et appareil de mesures electrochimiques recourant a des methodes statistiques |
| JP4352108B2 (ja) * | 1998-12-15 | 2009-10-28 | アークレイ株式会社 | 基質の定量方法 |
| US6475372B1 (en) | 2000-02-02 | 2002-11-05 | Lifescan, Inc. | Electrochemical methods and devices for use in the determination of hematocrit corrected analyte concentrations |
| JP2001021525A (ja) * | 1999-07-02 | 2001-01-26 | Akebono Brake Res & Dev Center Ltd | バイオセンサを用いた測定方法 |
| JP4288775B2 (ja) | 1999-07-29 | 2009-07-01 | 株式会社エクォス・リサーチ | Ｃｏガスセンサ |
| AU7590300A (en) * | 1999-09-20 | 2001-04-24 | Roche Diagnostics Corporation | Small volume biosensor for continuous analyte monitoring |
| JP4050434B2 (ja) | 1999-11-29 | 2008-02-20 | 松下電器産業株式会社 | サンプルの弁別方法 |
| JP3972063B2 (ja) | 2001-01-17 | 2007-09-05 | アークレイ株式会社 | センサを用いる定量分析方法および定量分析装置 |
| WO2002077633A1 (en) | 2001-03-23 | 2002-10-03 | The Regents Of The University Of California | Open circuit potential amperometry and voltammetry |
| DE10119527A1 (de) | 2001-04-12 | 2002-11-07 | Sitec Sensortechnik Gmbh | Verfahren zur mobilen oder stationären Erfassung von Körperfunktions- und Stoffwechseldaten eines lebenden Körpers und Einrichtung zur Durchführung des Verfahrens |
| US6721586B2 (en) | 2001-06-12 | 2004-04-13 | Lifescan, Inc. | Percutaneous biological fluid sampling and analyte measurement devices and methods |
| US20030113933A1 (en) | 2001-12-18 | 2003-06-19 | Rasmus Jansson | Analysis of components in liquids |
| CA2472584A1 (en) | 2002-01-15 | 2003-07-24 | Agamatrix, Inc. | Method and apparatus for processing electrochemical signals |
| WO2004011921A1 (ja) | 2002-07-25 | 2004-02-05 | Arkray, Inc. | 試料分析方法および試料分析装置 |
| AU2003283935A1 (en) | 2002-12-09 | 2004-06-30 | Otre Ab | Simplified signal processing method for voltammetry |
| JP4449431B2 (ja) | 2003-11-19 | 2010-04-14 | パナソニック株式会社 | 基質濃度の測定方法 |
| WO2005073708A2 (de) | 2004-01-29 | 2005-08-11 | Siemens Aktiengesellschaft | Verfahren zur messung der konzentration oder konzentrationsänderung einer redoxaktiven substanz und zugehörige vorrichtung |
| WO2005114164A2 (en) * | 2004-05-14 | 2005-12-01 | Bayer Healthcare Llc | Voltammetric systems for assaying biological analytes |
| JP4988581B2 (ja) | 2004-10-12 | 2012-08-01 | バイエル・ヘルスケア・エルエルシー | 拡散隔膜レイヤーにおける濃度測定 |
| WO2007013915A1 (en) * | 2005-07-20 | 2007-02-01 | Bayer Healthcare Llc | Gated amperometry |
| WO2007040913A1 (en) * | 2005-09-30 | 2007-04-12 | Bayer Healthcare Llc | Gated voltammetry |
| US7468125B2 (en) | 2005-10-17 | 2008-12-23 | Lifescan, Inc. | System and method of processing a current sample for calculating a glucose concentration |
| CN101437443B (zh) * | 2006-05-08 | 2011-11-30 | 拜尔健康护理有限责任公司 | 生物传感器用的异常输出检测系统 |
| EP3543348B1 (en) * | 2006-09-22 | 2020-11-18 | Ascensia Diabetes Care Holdings AG | Biosensor system having enhanced stability and hematocrit performance |
| EP3753481B1 (en) * | 2006-10-24 | 2024-07-17 | Ascensia Diabetes Care Holdings AG | Transient decay amperometry device |
| ATE523777T1 (de) | 2007-07-26 | 2011-09-15 | Nipro Diagnostics Inc | System und verfahren zur bestimmung der analytkonzentration mittels zeitaufgelöster amperometrie |
| US8101062B2 (en) | 2007-07-26 | 2012-01-24 | Nipro Diagnostics, Inc. | System and methods for determination of analyte concentration using time resolved amperometry |
| EP3395954B1 (en) * | 2007-12-10 | 2020-07-01 | Ascensia Diabetes Care Holdings AG | Rapid-read gated amperometry |
-
2008
- 2008-10-23 EP EP18176551.2A patent/EP3395954B1/en active Active
- 2008-10-23 RU RU2010128649/15A patent/RU2491549C2/ru active
- 2008-10-23 WO PCT/US2008/080865 patent/WO2009075951A1/en not_active Ceased
- 2008-10-23 EP EP20165626.1A patent/EP3690058B1/en active Active
- 2008-10-23 MX MX2010006393A patent/MX2010006393A/es active IP Right Grant
- 2008-10-23 BR BRPI0820718-6A patent/BRPI0820718A2/pt not_active Application Discontinuation
- 2008-10-23 EP EP08860137.2A patent/EP2222867B1/en active Active
- 2008-10-23 JP JP2010538008A patent/JP5455924B2/ja active Active
- 2008-10-23 CA CA2707300A patent/CA2707300C/en not_active Expired - Fee Related
- 2008-10-23 CN CN200880120045.5A patent/CN101896619B/zh active Active
- 2008-10-23 CN CN201710080974.9A patent/CN107091870B/zh active Active
- 2008-11-10 TW TW97143312A patent/TWI468679B/zh not_active IP Right Cessation
- 2008-11-14 US US12/271,032 patent/US8147674B2/en active Active
-
2012
- 2012-02-21 US US13/401,222 patent/US9034160B2/en active Active
-
2015
- 2015-04-16 US US14/688,055 patent/US10345255B2/en active Active
-
2019
- 2019-05-22 US US16/419,957 patent/US10908112B2/en active Active
-
2021
- 2021-01-13 US US17/148,293 patent/US20210148851A1/en not_active Abandoned
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6413411B1 (en) * | 1995-02-09 | 2002-07-02 | Tall Oak Ventures | Method and apparatus for amperometric diagnostic analysis |
| TW200630070A (en) * | 2004-10-21 | 2006-09-01 | Bayer Healthcare Llc | Method of determining the concentration of an analyte in a body fluid and system therefor |
| TW200716965A (en) * | 2005-05-25 | 2007-05-01 | Bayer Healthcare Llc | Methods of using raman spectral information in determining analyte concentrations |
Also Published As
| Publication number | Publication date |
|---|---|
| EP2222867A1 (en) | 2010-09-01 |
| CA2707300A1 (en) | 2009-06-18 |
| US20190331630A1 (en) | 2019-10-31 |
| CN107091870B (zh) | 2019-10-08 |
| EP3395954A1 (en) | 2018-10-31 |
| US10345255B2 (en) | 2019-07-09 |
| EP3690058B1 (en) | 2021-12-29 |
| EP3395954B1 (en) | 2020-07-01 |
| CN101896619B (zh) | 2017-04-05 |
| TW200925592A (en) | 2009-06-16 |
| US20210148851A1 (en) | 2021-05-20 |
| CA2707300C (en) | 2017-09-26 |
| US9034160B2 (en) | 2015-05-19 |
| BRPI0820718A2 (pt) | 2015-06-16 |
| US20120211361A1 (en) | 2012-08-23 |
| US20150219586A1 (en) | 2015-08-06 |
| WO2009075951A1 (en) | 2009-06-18 |
| US10908112B2 (en) | 2021-02-02 |
| EP2222867B1 (en) | 2018-07-11 |
| CN107091870A (zh) | 2017-08-25 |
| MX2010006393A (es) | 2010-06-25 |
| RU2491549C2 (ru) | 2013-08-27 |
| CN101896619A (zh) | 2010-11-24 |
| JP5455924B2 (ja) | 2014-03-26 |
| US8147674B2 (en) | 2012-04-03 |
| JP2011506964A (ja) | 2011-03-03 |
| EP3690058A1 (en) | 2020-08-05 |
| US20090145779A1 (en) | 2009-06-11 |
| RU2010128649A (ru) | 2012-01-20 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| TWI468679B (zh) | 決定樣本中之待測物濃度的方法及使用該方法的手持式測量裝置和生物感測器系統 | |
| US10921278B2 (en) | Slope-based compensation including secondary output signals | |
| CN101999073B (zh) | 斜率式补偿 | |
| EP1839571A1 (en) | Methods for analyzing a sample in the presence of interferents | |
| JP2009536744A (ja) | バイオセンサ用異常出力検出システム | |
| ES2823199T3 (es) | Amperometría de pulsos con lectura rápida | |
| HK1146302B (en) | Rapid-read gated amperometry | |
| HK1243163A1 (en) | Measurement device, biosensor system and method for determining concentration of analyte | |
| HK1146302A (en) | Rapid-read gated amperometry | |
| HK1243163B (zh) | 确定分析物浓度的测量装置、生物传感器系统和方法 | |
| HK1151704B (en) | Methods for analyzing a sample in the presence of interferents |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | Annulment or lapse of patent due to non-payment of fees |