TWI418353B - ３－（咪唑基）－吡唑并〔３，４－ｂ〕吡啶化物 - Google Patents

Info

Publication number

TWI418353B

TWI418353B TW097118925A TW97118925A TWI418353B TW I418353 B TWI418353 B TW I418353B TW 097118925 A TW097118925 A TW 097118925A TW 97118925 A TW97118925 A TW 97118925A TW I418353 B TWI418353 B TW I418353B

Authority

TW

Taiwan

Prior art keywords

compound

pyrazolo

ccr1

pyridin

chloro

Prior art date

2007-05-22

Links

• Espacenet
• Global Dossier
• Discuss

• HBWCPEPIJATHEA-UHFFFAOYSA-N 3-(1H-imidazol-2-yl)-2H-pyrazolo[3,4-b]pyridine Chemical class N1C(=NC=C1)C1=NNC2=NC=CC=C21 HBWCPEPIJATHEA-UHFFFAOYSA-N 0.000 title description 3
• 150000001875 compounds Chemical class 0.000 claims description 162
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• 239000003112 inhibitor Substances 0.000 claims description 28
• 150000003839 salts Chemical class 0.000 claims description 25
• 239000003814 drug Substances 0.000 claims description 17
• RAXXELZNTBOGNW-UHFFFAOYSA-N imidazole Natural products C1=CNC=N1 RAXXELZNTBOGNW-UHFFFAOYSA-N 0.000 claims description 17
• 239000008194 pharmaceutical composition Substances 0.000 claims description 16
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• 230000001404 mediated effect Effects 0.000 claims description 12
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• 239000003795 chemical substances by application Substances 0.000 claims description 9
• LEQAOMBKQFMDFZ-UHFFFAOYSA-N glyoxal Chemical compound O=CC=O LEQAOMBKQFMDFZ-UHFFFAOYSA-N 0.000 claims description 8
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• MTNDZQHUAFNZQY-UHFFFAOYSA-N imidazoline Chemical compound C1CN=CN1 MTNDZQHUAFNZQY-UHFFFAOYSA-N 0.000 claims description 5
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• 125000004194 piperazin-1-yl group Chemical group [H]N1C([H])([H])C([H])([H])N(*)C([H])([H])C1([H])[H] 0.000 description 9
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