PE20090293A1 - COMPUESTO DERIVADO DE 3-(IMIDAZOLIL)-PIRAZOLO[3,4-b]PIRIDINAS, PROCEDIMIENTO DE PREPARACION Y COMPOSICIONES FARMACEUTICAS - Google Patents

COMPUESTO DERIVADO DE 3-(IMIDAZOLIL)-PIRAZOLO[3,4-b]PIRIDINAS, PROCEDIMIENTO DE PREPARACION Y COMPOSICIONES FARMACEUTICAS

Info

Publication number
PE20090293A1
PE20090293A1 PE2008000878A PE2008000878A PE20090293A1 PE 20090293 A1 PE20090293 A1 PE 20090293A1 PE 2008000878 A PE2008000878 A PE 2008000878A PE 2008000878 A PE2008000878 A PE 2008000878A PE 20090293 A1 PE20090293 A1 PE 20090293A1
Authority
PE
Peru
Prior art keywords
pharmaceutical compositions
preparation procedure
imidazolil
pirazolo
pyridines
Prior art date
Application number
PE2008000878A
Other languages
English (en)
Spanish (es)
Inventor
Penglie Zhang
Andrew M K Pennell
Lianfa Li
Original Assignee
Chemocentryx Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chemocentryx Inc filed Critical Chemocentryx Inc
Publication of PE20090293A1 publication Critical patent/PE20090293A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/08—Antiseborrheics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Dermatology (AREA)
  • Pulmonology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Rheumatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Vascular Medicine (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Urology & Nephrology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PE2008000878A 2007-05-22 2008-05-22 COMPUESTO DERIVADO DE 3-(IMIDAZOLIL)-PIRAZOLO[3,4-b]PIRIDINAS, PROCEDIMIENTO DE PREPARACION Y COMPOSICIONES FARMACEUTICAS PE20090293A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US93294807P 2007-05-22 2007-05-22

Publications (1)

Publication Number Publication Date
PE20090293A1 true PE20090293A1 (es) 2009-04-04

Family

ID=40075474

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2008000878A PE20090293A1 (es) 2007-05-22 2008-05-22 COMPUESTO DERIVADO DE 3-(IMIDAZOLIL)-PIRAZOLO[3,4-b]PIRIDINAS, PROCEDIMIENTO DE PREPARACION Y COMPOSICIONES FARMACEUTICAS

Country Status (26)

Country Link
US (4) US7629344B2 (enExample)
EP (1) EP2155712B1 (enExample)
JP (1) JP5457338B2 (enExample)
KR (1) KR101534661B1 (enExample)
CN (1) CN101743238B (enExample)
AR (2) AR066701A1 (enExample)
AU (1) AU2008256862B2 (enExample)
BR (1) BRPI0811849A8 (enExample)
CA (1) CA2687625C (enExample)
CL (1) CL2008001493A1 (enExample)
CO (1) CO6241152A2 (enExample)
DK (1) DK2155712T3 (enExample)
EA (1) EA015529B1 (enExample)
ES (1) ES2600477T3 (enExample)
HU (1) HUE032273T2 (enExample)
IL (1) IL202248A (enExample)
JO (1) JO3319B1 (enExample)
MA (1) MA31442B1 (enExample)
MX (1) MX2009012567A (enExample)
NZ (1) NZ581405A (enExample)
PE (1) PE20090293A1 (enExample)
PL (1) PL2155712T3 (enExample)
PT (1) PT2155712T (enExample)
TW (1) TWI418353B (enExample)
UA (1) UA99619C2 (enExample)
WO (1) WO2008147815A1 (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7777035B2 (en) * 2005-06-22 2010-08-17 Chemocentryx, Inc. Azaindazole compounds and methods of use
ATE480532T1 (de) 2006-07-10 2010-09-15 Paion Uk Ltd Benzodiazepinsalze mit kurzzeitwirkung und polymorphe formen davon
AU2009291749B2 (en) * 2007-05-22 2015-05-21 Chemocentryx, Inc. 4-amino-3-(imidazolyl)-pyrazolo[3,4-d]pyrimidines
NZ581405A (en) * 2007-05-22 2011-06-30 Chemocentryx Inc 3-(Imidazolyl)-pyrazolo[3,4-b]pyridines and their use in treating CCR1-mediated disorders
EP2305647A1 (en) 2009-09-18 2011-04-06 PAION UK Limited Process for preparing 3-[(4S)-8-bromo-1-methyl-6-(2-pyridinyl)-4 H-imidazo[1,2-a][1,4]benzodiazepine-4-yl] propionic acid methyl ester or the benzene sulfonate salt thereof, and compounds useful in that process
EP2450039A1 (en) 2010-11-08 2012-05-09 PAION UK Ltd. Dosing regimen for sedation with CNS 7056 (Remimazolam)
JP6339573B2 (ja) * 2012-08-27 2018-06-06 ケモセントリックス，インコーポレイティド ケモカイン受容体のアンタゴニスト
MX2015007051A (es) 2012-12-07 2016-01-12 Chemocentryx Inc Diazol lactamas.
AR094963A1 (es) 2013-03-04 2015-09-09 Ono Pharmaceutical Co Reacción de oxidación excelente en el índice de conversión
US20170195506A1 (en) * 2015-12-30 2017-07-06 Kabushiki Kaisha Toshiba Image forming apparatus forming location free print system and print job retrieval method by the same
PL3439653T3 (pl) 2016-04-07 2021-07-05 Chemocentryx, Inc. Zmniejszenie obciążenia guzem przez podawanie antagonistów ccr1 w skojarzeniu z inhibitorami pd-1 lub inhibitorami pd-l1
BR112021025888A2 (pt) 2019-07-10 2022-04-26 Chemocentryx Inc Indanos como inibidores de pd-l1
CN114585359B (zh) 2019-10-16 2025-08-12 凯莫森特里克斯股份有限公司 用于治疗pd-l1疾病的杂芳基联苯酰胺
US11866429B2 (en) 2019-10-16 2024-01-09 Chemocentryx, Inc. Heteroaryl-biphenyl amines for the treatment of PD-L1 diseases

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US715746A (en) * 1902-02-25 1902-12-16 Nat Tube Co Apparatus for handling tube-plates.
US4166452A (en) 1976-05-03 1979-09-04 Generales Constantine D J Jr Apparatus for testing human responses to stimuli
US4256108A (en) 1977-04-07 1981-03-17 Alza Corporation Microporous-semipermeable laminated osmotic system
NZ188742A (en) 1977-10-26 1981-03-16 Wellcome Found Imidazolines and pesticidal compositions
AU518569B2 (en) 1979-08-07 1981-10-08 Farmos-Yhtyma Oy 4-benzyl- and 4-benzoyl imidazole derivatives
US4265874A (en) 1980-04-25 1981-05-05 Alza Corporation Method of delivering drug with aid of effervescent activity generated in environment of use
LU86084A1 (fr) 1985-09-20 1987-04-02 Faco Sa Apparei de massage electrique
US5102417A (en) 1985-11-07 1992-04-07 Expandable Grafts Partnership Expandable intraluminal graft, and method and apparatus for implanting an expandable intraluminal graft
US4800882A (en) 1987-03-13 1989-01-31 Cook Incorporated Endovascular stent and delivery system
US4886062A (en) 1987-10-19 1989-12-12 Medtronic, Inc. Intravascular radially expandable stent and method of implant
US4927942A (en) 1988-12-15 1990-05-22 Texaco Chemical Co. Method for the preparation of imidazoles
WO1990013332A1 (en) 1989-05-11 1990-11-15 Cedars-Sinai Medical Center Stent with sustained drug delivery
CA2049973C (en) 1990-02-28 2002-12-24 Rodney G. Wolff Intralumenal drug eluting prosthesis
US5419760A (en) 1993-01-08 1995-05-30 Pdt Systems, Inc. Medicament dispensing stent for prevention of restenosis of a blood vessel
US5429634A (en) 1993-09-09 1995-07-04 Pdt Systems Biogenic implant for drug delivery and method
US6774278B1 (en) 1995-06-07 2004-08-10 Cook Incorporated Coated implantable medical device
US5833651A (en) 1996-11-08 1998-11-10 Medtronic, Inc. Therapeutic intraluminal stents
US6294192B1 (en) 1999-02-26 2001-09-25 Lipocine, Inc. Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents
US7842693B2 (en) 2002-06-12 2010-11-30 Chemocentryx, Inc. Substituted piperazines
JP4723242B2 (ja) 2002-06-12 2011-07-13 ケモセントリックス インコーポレーティッド 炎症および免疫障害治療用ｃｃｒ１アンタゴニストとして使用するための１−アリール−４−置換ピペラジン誘導体
US20050256130A1 (en) 2002-06-12 2005-11-17 Chemocentryx, Inc. Substituted piperazines
US7589199B2 (en) 2002-06-12 2009-09-15 Chemocentryx, Inc. Substituted piperazines
US6770729B2 (en) 2002-09-30 2004-08-03 Medtronic Minimed, Inc. Polymer compositions containing bioactive agents and methods for their use
US7435831B2 (en) 2004-03-03 2008-10-14 Chemocentryx, Inc. Bicyclic and bridged nitrogen heterocycles
JP4845873B2 (ja) 2004-03-03 2011-12-28 ケモセントリックス インコーポレーティッド 二環式および架橋した窒素複素環
US7777035B2 (en) * 2005-06-22 2010-08-17 Chemocentryx, Inc. Azaindazole compounds and methods of use
PL1906965T3 (pl) * 2005-06-22 2015-10-30 Chemocentryx Inc Związki azaindazolowe i sposoby zastosowania
KR200434921Y1 (ko) * 2006-07-10 2007-01-02 서용석 야외용 간이 화장실
NZ581405A (en) * 2007-05-22 2011-06-30 Chemocentryx Inc 3-(Imidazolyl)-pyrazolo[3,4-b]pyridines and their use in treating CCR1-mediated disorders

Also Published As

Publication number Publication date
AU2008256862A1 (en) 2008-12-04
DK2155712T3 (en) 2016-12-19
JP2010528038A (ja) 2010-08-19
EA015529B1 (ru) 2011-08-30
CA2687625C (en) 2015-12-22
US20080300257A1 (en) 2008-12-04
US7629344B2 (en) 2009-12-08
IL202248A (en) 2015-04-30
PL2155712T3 (pl) 2017-02-28
NZ581405A (en) 2011-06-30
CA2687625A1 (en) 2008-12-04
US8481545B2 (en) 2013-07-09
JO3319B1 (ar) 2019-03-13
AU2008256862B2 (en) 2013-01-31
ES2600477T3 (es) 2017-02-09
PT2155712T (pt) 2016-12-13
TWI418353B (zh) 2013-12-11
MX2009012567A (es) 2010-02-17
CN101743238B (zh) 2014-04-30
EP2155712A1 (en) 2010-02-24
BRPI0811849A8 (pt) 2019-01-15
EA200901572A1 (ru) 2010-04-30
AR066701A1 (es) 2009-09-09
HK1141524A1 (zh) 2010-11-12
EP2155712A4 (en) 2011-05-11
US7960388B2 (en) 2011-06-14
AU2008256862A8 (en) 2009-12-24
EP2155712B1 (en) 2016-09-07
US20130184289A1 (en) 2013-07-18
WO2008147815A1 (en) 2008-12-04
CL2008001493A1 (es) 2008-08-29
UA99619C2 (en) 2012-09-10
US20120010214A1 (en) 2012-01-12
CO6241152A2 (es) 2011-01-20
JP5457338B2 (ja) 2014-04-02
TW200906402A (en) 2009-02-16
KR20100022998A (ko) 2010-03-03
BRPI0811849A2 (pt) 2014-11-18
KR101534661B1 (ko) 2015-07-09
US20100173911A1 (en) 2010-07-08
HUE032273T2 (en) 2017-09-28
CN101743238A (zh) 2010-06-16
AR110128A2 (es) 2019-02-27
MA31442B1 (fr) 2010-06-01
IL202248A0 (en) 2010-06-16

Similar Documents

Publication Publication Date Title
PE20090293A1 (es) COMPUESTO DERIVADO DE 3-(IMIDAZOLIL)-PIRAZOLO[3,4-b]PIRIDINAS, PROCEDIMIENTO DE PREPARACION Y COMPOSICIONES FARMACEUTICAS
PE20090902A1 (es) Combinacion de un antimitotico e inhibidor de aurora quinasa como agentes anticancerigenos
PE20051094A1 (es) Derivados de acido 7-fenilamino-4-quinolona-3-carboxilico y procesos para su preparacion
PE20090038A1 (es) Composiciones para mejorar la absorcion gastrointestinal de nutrientes y de farmacos
EA200701114A1 (ru) Азоловые производные с антимускариновой активностью
NO20081212L (no) Xantinderivater som selektive HM74A agonister
CL2011001082A1 (es) Compuestos derivados de amino-tetrahidropiranos sustituidos con heterociclos, composicion farmaceutica; y uso en el tratamiento de una afeccion seleccionada de resistencia a la insulina, hiperglicemia y diabetes de tipo 2.
NO20083630L (no) Nye pyridinderivater
PE20091687A1 (es) Derivados de piridina o pirazina como inhibidores de cinasa-pi-3
PE20120002A1 (es) Derivados de benceno sustituido con glucopiranosilo como inhibidores de sglt2
EA200970519A1 (ru) Полиморфы сукцината 2-[6-(3-аминопиперидин-1-ил)-3-метил-2,4-диоксо-3,4-дигидро-2h-пиримидин-1-илметил]-4-фторбензонитрил и способы их применения
ATE539748T1 (de) Glucokinaseaktivatoren
MA32508B1 (fr) Composes organiques
GEP201706772B (en) Parasiticidal oral veterinary compositions comprising systemically-acting active agents, methods and uses thereof
GEP20146003B (en) Benzothiazole derivatives as anticancer agents
SV2010003673A (es) Compuestos heterociclicos novedosos y usos de los mismos
CR9195A (es) Mezclas fungicidas
MX2009004767A (es) Preparacion liquida que comprende un complejo de pimobendan y ciclodextrina.
WO2006131649A3 (fr) Utilisation de la fumagilline et de ses derives pour augmenter la biodisponibilite des lactones macrocycliques
UY37971A (es) Derivados de indol macrocíclicos sustituidos
AR067751A1 (es) Composicion veterinaria topica, proceso para la preparacion de una composicion y metodo para el tratamiento de infeccion endoparasitaria o infestacion en un animal homeotermico
MX2007006539A (es) Sistema para la absorcion percutanea mejorada de los agentes beneficiadores de la piel.
AR076598A1 (es) Derivados espirociclicos de furan y tiofuran, procesos de preparacion y composiciones pesticidas
EA201071369A1 (ru) Композиции для лечения выпадения волос
PE20221272A1 (es) Agente supresor del sabor desagradable

Legal Events

Date Code Title Description
FG Grant, registration
FD Application declared void or lapsed