TWI380820B - 包含黃體激素及／或雌激素及５-甲基-（６ｓ）-四氫葉酸鹽之醫藥組合物 - Google Patents
包含黃體激素及／或雌激素及５-甲基-（６ｓ）-四氫葉酸鹽之醫藥組合物 Download PDFInfo
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- TWI380820B TWI380820B TW095116905A TW95116905A TWI380820B TW I380820 B TWI380820 B TW I380820B TW 095116905 A TW095116905 A TW 095116905A TW 95116905 A TW95116905 A TW 95116905A TW I380820 B TWI380820 B TW I380820B
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- Prior art keywords
- tetrahydrofolate
- methyl
- agent
- dosage units
- daily
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- METQSPRSQINEEU-HXCATZOESA-N drospirenone Chemical compound C([C@]12[C@H]3C[C@H]3[C@H]3[C@H]4[C@@H]([C@]5(CCC(=O)C=C5[C@@H]5C[C@@H]54)C)CC[C@@]31C)CC(=O)O2 METQSPRSQINEEU-HXCATZOESA-N 0.000 claims description 18
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Landscapes
- Health & Medical Sciences (AREA)
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
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| DE102005023301A DE102005023301B4 (de) | 2005-05-13 | 2005-05-13 | Pharmazeutische Zusammensetzung enthaltend Gestagene und/oder Estrogene und 5-Methyl-(6S)-tetrahydrofolat |
| US68509305P | 2005-05-25 | 2005-05-25 | |
| US78861806P | 2006-04-03 | 2006-04-03 | |
| DE102006016285A DE102006016285A1 (de) | 2006-04-03 | 2006-04-03 | Pharmazeutische Zusammensetzung enthaltend Gestagene und/oder Estrogene und 5-Methyl-(6S)-tetrahydrofolat |
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| TW200711651A TW200711651A (en) | 2007-04-01 |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| TWI508730B (zh) * | 2006-07-06 | 2015-11-21 | Bayer Ip Gmbh | 含四氫葉酸之醫藥組合物 |
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| UY29527A1 (es) | 2005-05-13 | 2006-12-29 | Schering Ag | Composicinn farmaccutica que contienen gestrgenos y/o estrngenos y 5-metil - (6s) - tetrhidrofolato. |
| EP1891959A1 (de) * | 2006-08-14 | 2008-02-27 | Bayer Schering Pharma Aktiengesellschaft | Pharmazeutische Zusammensetzung zur Kontrazeption und zur Verminderung des Risikos angeborener Fehlbildungen |
| EP2037935A1 (de) * | 2006-07-06 | 2009-03-25 | Bayer Schering Pharma AG | Pharmazeutische zubereitung zur kontrazeption und zur verminderung des risikos angeborener fehlbildungen |
| US8617597B2 (en) | 2006-07-06 | 2013-12-31 | Bayer Intellectual Property Gmbh | Pharmaceutical composition containing a tetrahydrofolic acid |
| CL2008000999A1 (es) * | 2007-04-05 | 2008-10-10 | Bayer Schering Pharma Ag | Composicion farmaceutica que comprende drospirenona y 17beta estradiol; kit farmaceutico que comprende a dicha composicion, util para terapia hormonal y contracepcion en mujeres. |
| CA2710293A1 (en) * | 2007-12-20 | 2009-07-02 | Teva Women's Health, Inc. | Dosage regimens and pharmaceutical compositions and packages for emergency contraception |
| TW200942242A (en) * | 2008-03-10 | 2009-10-16 | Rolf Schurmann | New drospirenone/17β-estradiol regimen, pharmaceutical combination product and kit for performing this regimen |
| WO2009112232A2 (en) * | 2008-03-10 | 2009-09-17 | Vladimir Hanes | New drospirenone/17beta-estradiol regimen, pharmaceutical combination product and kit for performing this regimen |
| US20130137664A1 (en) | 2010-04-15 | 2013-05-30 | Bayer Intellectual Property Gmbh | Low-dosed solid oral dosage forms for hrt |
| EP2383279A1 (en) | 2011-07-19 | 2011-11-02 | Pantarhei Bioscience B.V. | Process for the preparation of estetrol |
| EP2617422A1 (en) * | 2012-01-20 | 2013-07-24 | Isofol Medical AB | Anti-tumor activity of reduced folates like methylene-tetrahydrofolate, tetrahydrofolate or methyl-tetrahydrofolate |
| EP2781214A1 (en) | 2013-03-22 | 2014-09-24 | Chemo Research, S.L. | Formulation of amorphous calcium L-5-methyltetrahydrofolate (L-5-MTHF-Ca) |
| CN104490887A (zh) * | 2014-09-04 | 2015-04-08 | 连云港金康和信药业有限公司 | (6s)-5-甲基-四氢叶酸钙盐的稳定药物组合物 |
| SMT201800232T1 (it) | 2015-06-18 | 2018-07-17 | Mithra Pharmaceuticals S A | Unita' di dosaggio orodispersibile contenente un componente di estetrolo |
| LT3310333T (lt) | 2015-06-18 | 2020-06-25 | Estetra Sprl | Burnoje dirperguojama vaisto formą, turinti estetrolio komponentą |
| PT3310345T (pt) | 2015-06-18 | 2021-05-28 | Estetra Sprl | Comprimido orodispersível contendo estetrol |
| CA3178291A1 (en) | 2016-08-05 | 2018-04-12 | Estetra Srl | Method for the management of dysmenorrhea and menstrual pain |
| CN106336444A (zh) * | 2016-08-23 | 2017-01-18 | 国家卫生计生委科学技术研究所 | 一种新晶型炔雌醇 |
| JOP20200260A1 (ar) | 2018-04-19 | 2019-10-19 | Estetra Sprl | مركبات واستخداماتها للتخفيف من الأعراض المصاحبة لانقطاع الطمث |
| TWI801561B (zh) | 2018-04-19 | 2023-05-11 | 比利時商依思特拉私人有限責任公司 | 化合物及其用於緩解絕經相關症狀的用途 |
| TWI893101B (zh) | 2020-04-16 | 2025-08-11 | 比利時商埃斯特拉有限責任公司 | 具有降低之副作用之避孕組成物 |
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| WO1999053910A2 (en) * | 1998-04-17 | 1999-10-28 | Ortho-Mcneil Pharmaceutical, Inc. | Folic acid-containing pharmaceutical compositions, and related methods and delivery systems |
| US6011040A (en) * | 1997-06-13 | 2000-01-04 | Eprova Ag | Use of tetrahydrofolates in natural stereoisomeric form for the production of a pharmaceutical preparation suitable for influencing the homocysteine level, particularly for assisting the remethylation of homocysteine |
| WO2003070255A1 (en) * | 2002-02-21 | 2003-08-28 | Schering Aktiengesellschaft | Pharmaceutical compositions comprising one or more steroids one or more tetrahydrofolate components and vitamin b12 |
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| IE61236B1 (en) * | 1986-07-15 | 1994-10-19 | American Home Prod | Combination dosage form for pre-menopausal women |
| ZA939565B (en) * | 1993-12-21 | 1994-08-11 | Applied Analytical Ind Inc | Method for preparing low dose pharmaceutical products. |
| US6083528A (en) * | 1995-09-28 | 2000-07-04 | Schering Aktiengesellschaft | Hormone replacement therapy method and hormone dispenser |
| AU7522896A (en) * | 1995-10-27 | 1997-05-15 | Merck & Co., Inc. | Wet granulation formulation of a growth hormone secretagogue |
| PT877563E (pt) | 1996-01-31 | 2004-08-31 | Univ South Alabama | Preparacoes alimentares e vitaminicas contendo o isomero natural de folatos reduzidos |
| US6326392B1 (en) | 1997-11-06 | 2001-12-04 | American Home Products Corporation | Anti-estrogen plus progestin containing oral contraceptives |
| ID24568A (id) * | 1997-11-06 | 2000-07-27 | American Home Prod | Kontrasepsi oral yang mengandung anti-estrogen plus progestin |
| JP2002527484A (ja) * | 1998-10-19 | 2002-08-27 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフトング | セントジョーンズワートならびにジヒドロおよびテトラヒドロ葉酸の誘導体を含有する、うつ病の治療および予防のための天然製剤 |
| US7014865B1 (en) | 1998-10-19 | 2006-03-21 | Merck Patent Gmbh | Natural formulation for the treatment and prevention of depression, containing St. John's Wort and derivatives of dihydro- and tetrahydrofolic acid |
| CH693905A5 (de) | 1999-04-15 | 2004-04-15 | Eprova Ag | Stabile kristalline Salze von 5-Methyltetrahydrofolsäure. |
| HU225779B1 (en) | 1999-07-28 | 2007-08-28 | Chinoin Gyogyszer Es Vegyeszet | Pharmaceutical composition containing paracetamol and drotaverine and process for producing it |
| US6787531B1 (en) | 1999-08-31 | 2004-09-07 | Schering Ag | Pharmaceutical composition for use as a contraceptive |
| RS50262B (sr) | 1999-08-31 | 2009-07-15 | Bayer Schering Pharma Aktiengesellschaft, | Farmaceutska kombinacija etinilestradiola i drospirenona za primenu kao kontraceptivnog sredstva |
| US6479545B1 (en) | 1999-09-30 | 2002-11-12 | Drugtech Corporation | Formulation for menopausal women |
| UA73119C2 (en) | 2000-04-19 | 2005-06-15 | American Home Products Corpoir | Derivatives of cyclic thiocarbamates, pharmaceutical composition including noted derivatives of cyclic thiocarbamates and active ingredients of medicines as modulators of progesterone receptors |
| DE10022510A1 (de) | 2000-05-10 | 2001-11-15 | Basf Ag | Zusammensetzungen enthaltend Folsäure und reduziertes Folat |
| JP2004538262A (ja) * | 2000-12-14 | 2004-12-24 | タフツ ユニバーシティー | 関節炎状態を治療するための化合物および方法 |
| US20030045510A1 (en) * | 2000-12-15 | 2003-03-06 | Schloss Caroline Maxine | Estrogen-plus |
| EP1216713A1 (en) | 2000-12-20 | 2002-06-26 | Schering Aktiengesellschaft | Compositions of estrogen-cyclodextrin complexes |
| US20060034954A1 (en) * | 2001-02-02 | 2006-02-16 | Bland Jeffrey S | Medical composition for balancing bodily processes |
| US20040220118A1 (en) * | 2001-02-02 | 2004-11-04 | Bland Jeffrey S. | Medical composition for balancing bodily processes |
| UY29527A1 (es) | 2005-05-13 | 2006-12-29 | Schering Ag | Composicinn farmaccutica que contienen gestrgenos y/o estrngenos y 5-metil - (6s) - tetrhidrofolato. |
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2006
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2010
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| WO1999053910A2 (en) * | 1998-04-17 | 1999-10-28 | Ortho-Mcneil Pharmaceutical, Inc. | Folic acid-containing pharmaceutical compositions, and related methods and delivery systems |
| WO2003070255A1 (en) * | 2002-02-21 | 2003-08-28 | Schering Aktiengesellschaft | Pharmaceutical compositions comprising one or more steroids one or more tetrahydrofolate components and vitamin b12 |
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| TWI508730B (zh) * | 2006-07-06 | 2015-11-21 | Bayer Ip Gmbh | 含四氫葉酸之醫藥組合物 |
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