TWI368030B - Method and system for viewing a biological specimen - Google Patents

Method and system for viewing a biological specimen

Info

Publication number
TWI368030B
TWI368030B TW095146714A TW95146714A TWI368030B TW I368030 B TWI368030 B TW I368030B TW 095146714 A TW095146714 A TW 095146714A TW 95146714 A TW95146714 A TW 95146714A TW I368030 B TWI368030 B TW I368030B
Authority
TW
Taiwan
Prior art keywords
viewing
biological specimen
specimen
biological
Prior art date
Application number
TW095146714A
Other languages
English (en)
Chinese (zh)
Other versions
TW200730870A (en
Inventor
Scott Wolpert
David Zahniser
Original Assignee
Cytyc Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38173033&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=TWI368030(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Cytyc Corp filed Critical Cytyc Corp
Publication of TW200730870A publication Critical patent/TW200730870A/zh
Application granted granted Critical
Publication of TWI368030B publication Critical patent/TWI368030B/zh

Links

Classifications

    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/06—Means for illuminating specimens
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/06—Means for illuminating specimens
    • G02B21/08—Condensers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/12—Generating the spectrum; Monochromators
    • G01J3/18—Generating the spectrum; Monochromators using diffraction elements, e.g. grating
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/06—Means for illuminating specimens
    • G02B21/08—Condensers
    • G02B21/082—Condensers for incident illumination only
    • G02B21/084—Condensers for incident illumination only having annular illumination around the objective
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
    • G06V10/00—Arrangements for image or video recognition or understanding
    • G06V10/10—Image acquisition
    • G06V10/12—Details of acquisition arrangements; Constructional details thereof
    • G06V10/14—Optical characteristics of the device performing the acquisition or on the illumination arrangements
    • G06V10/141—Control of illumination
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
    • G06V20/00—Scenes; Scene-specific elements
    • G06V20/60—Type of objects
    • G06V20/69—Microscopic objects, e.g. biological cells or cellular parts
    • G06V20/693—Acquisition

Landscapes

  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Theoretical Computer Science (AREA)
  • Multimedia (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Microscoopes, Condenser (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Circuit Arrangement For Electric Light Sources In General (AREA)
TW095146714A 2005-12-20 2006-12-13 Method and system for viewing a biological specimen TWI368030B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US11/313,365 US7433026B2 (en) 2005-12-20 2005-12-20 Microscope with LED illumination source

Publications (2)

Publication Number Publication Date
TW200730870A TW200730870A (en) 2007-08-16
TWI368030B true TWI368030B (en) 2012-07-11

Family

ID=38173033

Family Applications (1)

Application Number Title Priority Date Filing Date
TW095146714A TWI368030B (en) 2005-12-20 2006-12-13 Method and system for viewing a biological specimen

Country Status (11)

Country Link
US (1) US7433026B2 (enExample)
EP (1) EP1971955A2 (enExample)
JP (1) JP2009520991A (enExample)
KR (1) KR101349664B1 (enExample)
CN (1) CN101341495B (enExample)
AU (1) AU2006340771B2 (enExample)
BR (1) BRPI0620052A2 (enExample)
CA (1) CA2631722C (enExample)
IL (1) IL192118A (enExample)
TW (1) TWI368030B (enExample)
WO (1) WO2007111735A2 (enExample)

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ITMI20050019A1 (it) * 2005-01-07 2006-07-08 Fraen Corp Srl Microscopio a fluorescenza in luce trasmessa e kit di adattamento di un microscopio alla modalita' di lavoro a fluorescenza in luce trasmessa
US7561329B2 (en) * 2006-12-14 2009-07-14 Cytyc Corporation Illumination source for stained biological samples
CN101828139A (zh) * 2007-09-05 2010-09-08 致茂电子股份有限公司 具有波长转换磷光体的光源
US7848019B2 (en) * 2007-12-10 2010-12-07 Cytyc Corporation Microscope calibration apparatus and method and stage including calibration apparatus
US8325414B2 (en) * 2007-12-27 2012-12-04 Cytyc Corporation Apparatus for single-handed control of microscope functions
US8174763B2 (en) * 2007-12-27 2012-05-08 Cytyc Corporation Methods and systems for controlably scanning a cytological specimen
GB0809252D0 (en) * 2008-05-21 2008-06-25 Ntnu Technology Transfer As Underwater hyperspectral imaging
DE102009005839A1 (de) * 2009-01-21 2010-07-22 Carl Zeiss Surgical Gmbh Lichtquelle für ein optisches Beobachtungsgerät
US9310598B2 (en) 2009-03-11 2016-04-12 Sakura Finetek U.S.A., Inc. Autofocus method and autofocus device
JP5253309B2 (ja) * 2009-07-02 2013-07-31 オリンパス株式会社 顕微鏡システム、及び該制御方法
US10139613B2 (en) 2010-08-20 2018-11-27 Sakura Finetek U.S.A., Inc. Digital microscope and method of sensing an image of a tissue sample
US9060684B2 (en) 2010-08-30 2015-06-23 Panasonic Healthcare Holdings Co., Ltd. Observation device, observation program, and observation system
WO2012090416A1 (ja) * 2010-12-28 2012-07-05 オリンパス株式会社 検査装置
JP5445499B2 (ja) * 2011-03-30 2014-03-19 三洋電機株式会社 観察装置
WO2013074978A1 (en) 2011-11-17 2013-05-23 Datalogic ADC, Inc. Systems and methods for reading color optical codes
JP5892594B2 (ja) * 2012-01-24 2016-03-23 学校法人東京電機大学 複数点照明による培養細胞観察システム
DE102013006996A1 (de) 2013-04-19 2014-10-23 Carl Zeiss Microscopy Gmbh Verfahren zur Beleuchtung eines Objektes in einem digitalen Lichtmikroskop, digitales Lichtmikroskop und Hellfeld-Auflichtbeleuchtungsvorrichtung für ein digitales Lichtmikroskop
DE102013103971A1 (de) 2013-04-19 2014-11-06 Sensovation Ag Verfahren zum Erzeugen eines aus mehreren Teilbildern zusammengesetzten Gesamtbilds eines Objekts
JP5866534B2 (ja) * 2013-07-11 2016-02-17 パナソニックＩｐマネジメント株式会社 画像計測装置及び画像計測方法
US10007102B2 (en) 2013-12-23 2018-06-26 Sakura Finetek U.S.A., Inc. Microscope with slide clamping assembly
JP6550262B2 (ja) * 2015-05-08 2019-07-24 オリンパス株式会社 顕微鏡システムおよび照明操作装置
DE102015116488A1 (de) 2015-09-29 2017-03-30 Carl Zeiss Microscopy Gmbh Mikroskop sowie Beleuchtungsvorrichtung und Beleuchtungssatz für ein Mikroskop
DE102016116621A1 (de) * 2016-09-06 2019-04-18 Stiftung Caesar Center Of Advanced European Studies And Research LED-Beleuchtungsmodul für ein Mikroskop
DE102016015870A1 (de) 2016-09-06 2019-04-04 Stiftung Caesar Center Of Advanced European Studies And Research LED-Beleuchtungsmodul für ein Mikroskop
US11280803B2 (en) 2016-11-22 2022-03-22 Sakura Finetek U.S.A., Inc. Slide management system
US10268860B2 (en) * 2016-12-22 2019-04-23 Datalogic ADC, Inc. White illumination for barcode scanners with improved power efficiency and cost
DE102017115658A1 (de) * 2017-07-12 2019-01-17 Carl Zeiss Microscopy Gmbh Flackern bei Winkel-variabler Beleuchtung
EP3669179B1 (en) 2017-08-17 2023-07-19 Abbott Point Of Care Inc Systems for performing optical and electrochemical assays
WO2019035077A1 (en) 2017-08-17 2019-02-21 Abbott Point Of Care Inc. DEVICES, SYSTEMS AND METHODS FOR PERFORMING OPTICAL ASSAYS
CN108050429B (zh) * 2017-12-12 2025-01-07 苏州科医世凯半导体技术有限责任公司 一种led多光谱共光路光源照明装置
CN109060309B (zh) * 2018-06-28 2024-04-02 广东工业大学 一种色差最优分辨配色仪及其测试方法
CN110927950A (zh) * 2019-12-25 2020-03-27 上海睿钰生物科技有限公司 荧光照明装置和显微成像系统
CN115210753A (zh) * 2020-05-13 2022-10-18 3M创新有限公司 用于菌落计数的图像中的强度差异补偿
CN116482848B (zh) * 2023-04-28 2023-10-24 广州市明美光电技术有限公司 一种用于光学仪器的匀光光源系统、方法及显微镜

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JPH07122694B2 (ja) 1986-10-16 1995-12-25 オリンパス光学工業株式会社 顕微鏡用照明装置
GB9703156D0 (en) * 1997-02-15 1997-04-02 Univ Strathclyde Optical element
US6016038A (en) * 1997-08-26 2000-01-18 Color Kinetics, Inc. Multicolored LED lighting method and apparatus
US6459919B1 (en) * 1997-08-26 2002-10-01 Color Kinetics, Incorporated Precision illumination methods and systems
JP2001041882A (ja) * 1999-07-28 2001-02-16 Kubota Corp 検卵装置
CN1292286A (zh) * 1999-09-23 2001-04-25 上海第二医科大学附属瑞金医院 含木芙蓉叶提取物的药剂及制备方法
AU780529B2 (en) * 1999-10-29 2005-03-24 Cytyc Corporation Cytological imaging system and method
US6665060B1 (en) * 1999-10-29 2003-12-16 Cytyc Corporation Cytological imaging system and method
EP1150154B1 (de) 2000-04-26 2003-03-26 COBRA electronic GmbH Anordnung und Verfahren zur ringförmigen Beleuchtung, insbesondere zur Auflichtbeleuchtung bei Mikroskopen
US6921920B2 (en) 2001-08-31 2005-07-26 Smith & Nephew, Inc. Solid-state light source
WO2003021853A2 (en) * 2001-09-05 2003-03-13 Genicon Sciences Corporation Apparatus for reading signals generated from resonance light scattered particle labels
JP3889992B2 (ja) * 2002-05-17 2007-03-07 株式会社ミツトヨ リング照明装置
US6683419B2 (en) * 2002-06-24 2004-01-27 Dialight Corporation Electrical control for an LED light source, including dimming control
CA2505967A1 (en) * 2002-11-27 2004-06-17 3M Innovative Properties Company Biological growth plate scanner
DE20304412U1 (de) * 2003-03-19 2003-06-12 Schott Glas, 55122 Mainz Steuereinheit für Mischlichtbeleuchtungen
JP2005017905A (ja) * 2003-06-27 2005-01-20 Olympus Corp 実体顕微鏡
JP2005070021A (ja) * 2003-08-28 2005-03-17 Yokogawa Electric Corp 検査用光源装置
DE10339618A1 (de) * 2003-08-28 2005-03-24 Leica Microsystems (Schweiz) Ag Leuchtdioden-Beleuchtung für ein optisches Beobachtungsgerät, insbesondere ein Stereo- oder ein Stereooperationsmikroskop
JP4091079B2 (ja) * 2003-11-14 2008-05-28 オリンパス株式会社 マルチスペクトル撮像装置、マルチスペクトル照明装置
JP4290131B2 (ja) * 2004-03-31 2009-07-01 キヤノン株式会社 記録媒体識別装置および記録装置

Also Published As

Publication number Publication date
CN101341495B (zh) 2011-09-21
IL192118A (en) 2013-01-31
US20070139638A1 (en) 2007-06-21
TW200730870A (en) 2007-08-16
IL192118A0 (en) 2009-08-03
AU2006340771A1 (en) 2007-10-04
KR101349664B1 (ko) 2014-01-09
EP1971955A2 (en) 2008-09-24
KR20080077988A (ko) 2008-08-26
CA2631722C (en) 2013-07-30
CA2631722A1 (en) 2007-10-04
JP2009520991A (ja) 2009-05-28
AU2006340771B2 (en) 2011-04-14
WO2007111735A2 (en) 2007-10-04
CN101341495A (zh) 2009-01-07
BRPI0620052A2 (pt) 2011-11-01
WO2007111735A3 (en) 2008-02-21
US7433026B2 (en) 2008-10-07

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