TWI342221B - Solid pharmaceutical dosage form - Google Patents

Solid pharmaceutical dosage form Download PDF

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Publication number
TWI342221B
TWI342221B TW093125927A TW93125927A TWI342221B TW I342221 B TWI342221 B TW I342221B TW 093125927 A TW093125927 A TW 093125927A TW 93125927 A TW93125927 A TW 93125927A TW I342221 B TWI342221 B TW I342221B
Authority
TW
Taiwan
Prior art keywords
dosage form
weight
soluble polymer
copolymer
surfactant
Prior art date
Application number
TW093125927A
Other languages
English (en)
Chinese (zh)
Other versions
TW200522979A (en
Inventor
Joerg Rosenberg
Ulrich Reinhold
Bernd Liepold
Gunther Berndl
Jorg Breitenbach
Laman Alani
Soumojeet Ghosh
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34217089&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=TWI342221(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of TW200522979A publication Critical patent/TW200522979A/zh
Application granted granted Critical
Publication of TWI342221B publication Critical patent/TWI342221B/zh

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • AIDS & HIV (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
TW093125927A 2003-08-28 2004-08-27 Solid pharmaceutical dosage form TWI342221B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10/650,178 US20050048112A1 (en) 2003-08-28 2003-08-28 Solid pharmaceutical dosage form

Publications (2)

Publication Number Publication Date
TW200522979A TW200522979A (en) 2005-07-16
TWI342221B true TWI342221B (en) 2011-05-21

Family

ID=34217089

Family Applications (1)

Application Number Title Priority Date Filing Date
TW093125927A TWI342221B (en) 2003-08-28 2004-08-27 Solid pharmaceutical dosage form

Country Status (31)

Country Link
US (1) US20050048112A1 (fr)
EP (6) EP2258346B1 (fr)
JP (6) JP4815348B2 (fr)
KR (5) KR101563222B1 (fr)
CN (5) CN102772380B (fr)
AT (1) ATE516017T1 (fr)
AU (3) AU2004283087C1 (fr)
CA (2) CA2536638C (fr)
CR (3) CR8256A (fr)
CY (5) CY1111981T1 (fr)
DK (5) DK2258346T3 (fr)
EA (4) EA033224B1 (fr)
EC (1) ECSP066397A (fr)
ES (5) ES2367173T3 (fr)
HK (4) HK1094766A1 (fr)
HR (1) HRP20110555T1 (fr)
HU (3) HUE038792T2 (fr)
IL (3) IL173939A (fr)
ME (2) MEP17608A (fr)
MX (2) MX358033B (fr)
NO (3) NO330282B1 (fr)
NZ (2) NZ579622A (fr)
PL (5) PL1663183T3 (fr)
PT (5) PT2258344E (fr)
RS (2) RS57663B1 (fr)
SG (3) SG145690A1 (fr)
SI (5) SI2258344T1 (fr)
TW (1) TWI342221B (fr)
UA (1) UA85564C2 (fr)
WO (1) WO2005039551A2 (fr)
ZA (3) ZA200801362B (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI381840B (zh) * 2005-02-23 2013-01-11 Abbott Lab 固態醫藥劑量配方

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KR101794032B1 (ko) * 2011-09-21 2017-11-07 (주)바이오시네틱스 나노입자 제조방법
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US9789063B2 (en) 2012-09-27 2017-10-17 Basf Se Storage-stable dust-free homogeneous particulate formulation
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CN104684545B (zh) 2012-09-27 2018-04-03 巴斯夫欧洲公司 包含至少一种水溶性维生素e衍生物和至少一种亲水聚合物的储存稳定的无粉尘均质颗粒状配制剂
JP6275726B2 (ja) 2012-09-27 2018-02-07 ビーエーエスエフ ソシエタス・ヨーロピアＢａｓｆ Ｓｅ 少なくとも１種の水溶性ビタミンｅ誘導体および少なくとも１種の親水性ポリマーを含む、保存において安定な無塵の均質な粒子製剤
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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI381840B (zh) * 2005-02-23 2013-01-11 Abbott Lab 固態醫藥劑量配方

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Publication number Publication date
EA201890737A3 (ru) 2019-01-31
AU2010238573A1 (en) 2010-11-18
PT2258345T (pt) 2017-01-20
EP1663183B9 (fr) 2012-06-13
CR8256A (es) 2008-01-11
KR101132602B1 (ko) 2012-04-06
PL2258345T3 (pl) 2017-03-31
CN102772380B (zh) 2015-08-19
CY1113596T1 (el) 2016-06-22
HK1094766A1 (en) 2007-04-13
ZA200601718B (en) 2009-11-25
AU2007249115B2 (en) 2010-08-12
UA85564C2 (ru) 2009-02-10
CN101919858A (zh) 2010-12-22
JP5498411B2 (ja) 2014-05-21
KR20150044031A (ko) 2015-04-23
DK2258345T3 (en) 2017-01-16
AU2004283087C1 (en) 2008-04-24
CR20120661A (es) 2013-03-13
NO330282B1 (no) 2011-03-21
EP1663183A2 (fr) 2006-06-07
RS20060140A (en) 2008-09-29
EP3354261A1 (fr) 2018-08-01
NO20061342L (no) 2006-05-29
KR20060121837A (ko) 2006-11-29
ATE516017T1 (de) 2011-07-15
NZ545499A (en) 2009-11-27
EP2258344A3 (fr) 2011-01-19
IL173939A (en) 2017-03-30
MEP17608A (en) 2010-06-10
PL1663183T3 (pl) 2011-10-31
ES2653762T3 (es) 2018-02-08
CA2536638A1 (fr) 2005-05-06
IL254581A0 (en) 2017-11-30
NZ579622A (en) 2011-01-28
SG179401A1 (en) 2012-04-27
CY1120138T1 (el) 2018-12-12
PL2258344T3 (pl) 2013-04-30
EP2258344B1 (fr) 2012-11-14
CA2689639C (fr) 2014-06-10
CN102764244A (zh) 2012-11-07
ECSP066397A (es) 2006-08-30
HUE031153T2 (en) 2017-07-28
CN1901884B (zh) 2012-07-25
DK2258346T3 (da) 2017-11-13
SI2942051T1 (en) 2018-06-29
RS57663B1 (sr) 2018-11-30
PL2258346T3 (pl) 2018-01-31
ZA200801361B (en) 2011-11-30
KR101281994B1 (ko) 2013-07-04
JP2016094433A (ja) 2016-05-26
MX358033B (es) 2018-08-02
SI2258346T1 (sl) 2017-12-29
KR20110122771A (ko) 2011-11-10
ES2367173T3 (es) 2011-10-31
EA200600473A1 (ru) 2006-10-27
HUE035985T2 (hu) 2018-06-28
JP5395125B2 (ja) 2014-01-22
EP2942051A1 (fr) 2015-11-11
HRP20110555T1 (hr) 2011-09-30
NO20100367L (no) 2006-05-29
PT1663183E (pt) 2011-08-25
ES2608720T3 (es) 2017-04-12
DK2258344T3 (da) 2013-01-02
JP4815348B2 (ja) 2011-11-16
HK1145969A1 (en) 2011-05-13
JP2007504142A (ja) 2007-03-01
IL173939A0 (en) 2006-07-05
CR20120662A (es) 2013-03-13
WO2005039551A2 (fr) 2005-05-06
EP2258346A3 (fr) 2011-01-19
DK1663183T3 (da) 2011-08-29
CN1901884A (zh) 2007-01-24
ZA200801362B (en) 2009-03-25
EA200900292A1 (ru) 2009-06-30
EA201890737A2 (ru) 2018-08-31
EP2258344A2 (fr) 2010-12-08
KR20140046078A (ko) 2014-04-17
EP2258346B1 (fr) 2017-09-27
EP2942051B1 (fr) 2018-01-17
CN105106104A (zh) 2015-12-02
HUE038792T2 (hu) 2018-11-28
CY1118505T1 (el) 2017-07-12
EA201301045A1 (ru) 2014-05-30
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MXPA06002346A (es) 2006-05-19
HK1257502A1 (zh) 2019-10-25
AU2010238573B2 (en) 2012-12-13
SI2258344T1 (sl) 2013-03-29
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TW200522979A (en) 2005-07-16
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KR101457967B1 (ko) 2014-11-07
US20050048112A1 (en) 2005-03-03
AU2004283087A1 (en) 2005-05-06
PT2258344E (pt) 2013-02-18
EP2258346A2 (fr) 2010-12-08
CY1119651T1 (el) 2018-04-04
CN102772380A (zh) 2012-11-14
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IL207260A (en) 2017-10-31
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SG10201507902UA (en) 2015-10-29
NO334418B1 (no) 2014-03-03
ME00130B (fr) 2010-10-10
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CA2689639A1 (fr) 2005-05-06
PT2942051T (pt) 2018-04-23
CY1111981T1 (el) 2015-11-04
EA033224B1 (ru) 2019-09-30
NO335326B1 (no) 2014-11-10
SI2258345T1 (sl) 2017-01-31
DK2942051T3 (en) 2018-05-07
EP2258345B1 (fr) 2016-09-21
AU2007249115A1 (en) 2008-01-10
EP2258345A3 (fr) 2011-01-19
EP2258345A2 (fr) 2010-12-08
WO2005039551A3 (fr) 2006-08-03

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