TWI340139B - Organic compounds - Google Patents

Organic compounds

Info

Publication number
TWI340139B
TWI340139B TW093112339A TW93112339A TWI340139B TW I340139 B TWI340139 B TW I340139B TW 093112339 A TW093112339 A TW 093112339A TW 93112339 A TW93112339 A TW 93112339A TW I340139 B TWI340139 B TW I340139B
Authority
TW
Taiwan
Prior art keywords
organic compounds
compounds
organic
Prior art date
Application number
TW093112339A
Other languages
English (en)
Other versions
TW200505920A (en
Inventor
Stephen Paul Collingwood
Brian Cox
Urs Baettig
Gurdip Bhalay
Nicholas James Devereux
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=33420896&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=TWI340139(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB0324887A external-priority patent/GB0324887D0/en
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of TW200505920A publication Critical patent/TW200505920A/zh
Application granted granted Critical
Publication of TWI340139B publication Critical patent/TWI340139B/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Otolaryngology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
TW093112339A 2003-05-02 2004-04-30 Organic compounds TWI340139B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0310232 2003-05-02
GB0324887A GB0324887D0 (en) 2003-10-24 2003-10-24 Organic compounds

Publications (2)

Publication Number Publication Date
TW200505920A TW200505920A (en) 2005-02-16
TWI340139B true TWI340139B (en) 2011-04-11

Family

ID=33420896

Family Applications (1)

Application Number Title Priority Date Filing Date
TW093112339A TWI340139B (en) 2003-05-02 2004-04-30 Organic compounds

Country Status (32)

Country Link
US (2) US20070060563A1 (zh)
EP (1) EP1631569B1 (zh)
JP (1) JP4416786B2 (zh)
KR (1) KR100896544B1 (zh)
AR (1) AR044134A1 (zh)
AT (1) ATE440840T1 (zh)
AU (1) AU2004234069B2 (zh)
BR (1) BRPI0410238A (zh)
CA (1) CA2523436C (zh)
CL (1) CL2004000918A1 (zh)
CO (1) CO5700782A2 (zh)
CY (1) CY1109655T1 (zh)
DE (1) DE602004022805D1 (zh)
DK (1) DK1631569T3 (zh)
EC (1) ECSP056134A (zh)
ES (1) ES2331185T3 (zh)
HK (1) HK1087704A1 (zh)
HR (1) HRP20050933A2 (zh)
IL (1) IL171591A (zh)
IS (1) IS2746B (zh)
MA (1) MA27775A1 (zh)
MX (1) MXPA05011739A (zh)
MY (1) MY142652A (zh)
NO (1) NO20055688L (zh)
NZ (1) NZ542995A (zh)
PE (1) PE20050465A1 (zh)
PL (1) PL1631569T3 (zh)
PT (1) PT1631569E (zh)
RU (1) RU2363700C2 (zh)
SI (1) SI1631569T1 (zh)
TW (1) TWI340139B (zh)
WO (1) WO2004096800A2 (zh)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2239546B1 (es) * 2004-03-15 2006-12-01 Almirall Prodesfarma, S.A. Nuevos esteres de quinuclidina cuaternizados.
GB0410712D0 (en) 2004-05-13 2004-06-16 Novartis Ag Organic compounds
GB0424284D0 (en) * 2004-11-02 2004-12-01 Novartis Ag Organic compounds
GB0428416D0 (en) * 2004-12-24 2005-02-02 Novartis Ag Organic compounds
GB0601951D0 (en) 2006-01-31 2006-03-15 Novartis Ag Organic compounds
EP1900737A1 (en) * 2006-08-31 2008-03-19 Novartis AG Polymorph of (R)-3-(2-hydroxy-2,2-diphenyl-acetoxy)-1-(isoxazol-3-ylcarbamoyl-methyl)-1-azonia-bicyclo-[2.2.2]octane bromide
EP1894568A1 (en) * 2006-08-31 2008-03-05 Novartis AG Pharmaceutical compositions for the treatment of inflammatory or obstructive airway diseases
TW200825084A (en) * 2006-11-14 2008-06-16 Astrazeneca Ab New compounds 521
RU2009120229A (ru) * 2006-12-19 2011-01-27 Астразенека Аб (Se) Производные хинуклидинола в качестве антагонистов мускариновых рецепторов
EP1950196A1 (de) * 2007-01-29 2008-07-30 Boehringer Ingelheim Pharma GmbH & Co. KG Verfahren zur Herstellung von Ammoniumhexafluorophosphaten
WO2009035542A2 (en) 2007-09-07 2009-03-19 Theravance, Inc. Guanidine-containing compounds useful as muscarinic receptor antagonists
EP2222637A1 (en) 2007-12-14 2010-09-01 Theravance, Inc. Amidine-containing compounds useful as muscarinic receptor antagonists
PL2231642T3 (pl) 2008-01-11 2014-04-30 Novartis Ag Pirymidyny jako inhibitory kinazy
EA017627B1 (ru) * 2008-05-13 2013-01-30 Астразенека Аб Хинуклидиновые производные в качестве антагонистов мускаринового м3 рецептора
BRPI0912657A2 (pt) * 2008-05-13 2016-01-26 Astrazeneca Ab produto farmacêutico compreendendo um antagonista de receptor muscarínico e um agonista beta2-adrenorreceptor
GB0808709D0 (en) * 2008-05-13 2008-06-18 Astrazeneca Ab New combination 295
US20090326004A1 (en) 2008-06-03 2009-12-31 Ranbaxy Laboratories Limited Muscarinic receptor antagonists
WO2009153536A1 (en) * 2008-06-17 2009-12-23 Argenta Discovery Limited 1-aza-bicyclo [2.2.2] octane derivatives useful as muscarinic receptor antagonists
GB0811100D0 (en) * 2008-06-17 2008-07-23 Astrazeneca Ab New combination
EP2585459B1 (en) * 2010-06-22 2015-01-07 Chiesi Farmaceutici S.p.A. Alkaloid aminoester derivatives and medicinal compositions thereof
UY33597A (es) 2010-09-09 2012-04-30 Irm Llc Compuestos y composiciones como inhibidores de la trk
WO2012034095A1 (en) 2010-09-09 2012-03-15 Irm Llc Compounds and compositions as trk inhibitors
US9102671B2 (en) 2011-02-25 2015-08-11 Novartis Ag Compounds and compositions as TRK inhibitors
JP2011195593A (ja) * 2011-06-30 2011-10-06 Astrazeneca Ab ムスカリンｍ３受容体アンタゴニストとしてのキヌクリジン誘導体
CN104011043B (zh) * 2011-12-30 2016-11-16 奇斯药制品公司 作为抗毒蕈碱剂的1-氮杂杂环基乙酸的奎宁环酯、它们的制备方法及其药用组合物
CN104470515B (zh) 2012-05-03 2016-12-07 圣路易斯药学院 用于增加神经营养肽的组合物和方法
TWI647227B (zh) * 2013-02-28 2019-01-11 日商安斯泰來製藥股份有限公司 ２－醯胺噻唑衍生物或其鹽
CZ306791B6 (cs) 2013-10-29 2017-07-12 Zentiva, K.S. Průmyslově využitelný způsob přípravy aklidinium bromidu o vysoké čistotě
PT108370B (pt) * 2015-03-30 2018-10-25 Hovione Farm S A Processo de preparação de brometo de aclidínio
PT3111978T (pt) 2015-07-03 2021-12-06 Novartis Ag Inalador adaptado para ler informação armazenada num meio de armazenamento de dados de um recipiente

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1219606A (en) * 1968-07-15 1971-01-20 Rech S Et D Applic Scient Soge Quinuclidinol derivatives and preparation thereof
DK534178A (da) * 1977-12-16 1979-06-17 Interx Research Corp Anticholinerge midler med sektrtionshaemmende virkning
ES2165768B1 (es) * 1999-07-14 2003-04-01 Almirall Prodesfarma Sa Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen.
EP1302458A4 (en) * 2000-07-11 2005-10-19 Banyu Pharma Co Ltd ESTERDERIVATE
EE05404B1 (et) * 2000-12-28 2011-04-15 Almirall Prodesfarma Ag Kinuklidiini derivaat, selle saamine ja kasutamine ravimi valmistamiseks, mis on ette n„htud respiratoorsete, kuseelundite v?i mao-soolte haiguste ravimiseks, ning seda sisaldav ravimkompositsioon
US7452904B2 (en) * 2001-12-20 2008-11-18 Chiesi Farmaceutici S.P.A. 1-alkyl-1-azoniabicyclo' 2.2.2 octane carbamate derivatives and their use as muscarinic receptor antagonists
GB0424284D0 (en) * 2004-11-02 2004-12-01 Novartis Ag Organic compounds
EP1900737A1 (en) * 2006-08-31 2008-03-19 Novartis AG Polymorph of (R)-3-(2-hydroxy-2,2-diphenyl-acetoxy)-1-(isoxazol-3-ylcarbamoyl-methyl)-1-azonia-bicyclo-[2.2.2]octane bromide

Also Published As

Publication number Publication date
MXPA05011739A (es) 2006-01-26
EP1631569B1 (en) 2009-08-26
PL1631569T3 (pl) 2010-02-26
BRPI0410238A (pt) 2006-05-16
US20100041887A1 (en) 2010-02-18
HRP20050933A2 (en) 2006-12-31
US8168654B2 (en) 2012-05-01
IS2746B (is) 2011-08-15
WO2004096800A2 (en) 2004-11-11
MA27775A1 (fr) 2006-02-01
CA2523436C (en) 2011-11-01
PE20050465A1 (es) 2005-07-18
CO5700782A2 (es) 2006-11-30
CY1109655T1 (el) 2014-08-13
NZ542995A (en) 2009-02-28
AU2004234069B2 (en) 2008-02-21
PT1631569E (pt) 2009-11-26
CA2523436A1 (en) 2004-11-11
DK1631569T3 (da) 2009-11-23
NO20055688D0 (no) 2005-12-01
US20070060563A1 (en) 2007-03-15
TW200505920A (en) 2005-02-16
ATE440840T1 (de) 2009-09-15
HK1087704A1 (en) 2006-10-20
AU2004234069A1 (en) 2004-11-11
EP1631569A2 (en) 2006-03-08
DE602004022805D1 (de) 2009-10-08
ECSP056134A (es) 2006-04-19
WO2004096800A3 (en) 2005-01-06
KR20060015572A (ko) 2006-02-17
AR044134A1 (es) 2005-08-24
JP2006525267A (ja) 2006-11-09
RU2005137360A (ru) 2006-07-27
IS8158A (is) 2005-11-30
MY142652A (en) 2010-12-15
NO20055688L (no) 2006-01-09
JP4416786B2 (ja) 2010-02-17
IL171591A (en) 2010-11-30
KR100896544B1 (ko) 2009-05-07
ES2331185T3 (es) 2009-12-23
RU2363700C2 (ru) 2009-08-10
CL2004000918A1 (es) 2005-02-11
SI1631569T1 (sl) 2010-01-29

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Legal Events

Date Code Title Description
MM4A Annulment or lapse of patent due to non-payment of fees