TWI317653B - Centrifuge with removable core for scalable centrifugation, and method for achieving linear separation of particles of a product during centrifugation - Google Patents

Centrifuge with removable core for scalable centrifugation, and method for achieving linear separation of particles of a product during centrifugation

Info

Publication number
TWI317653B
TWI317653B TW091134339A TW91134339A TWI317653B TW I317653 B TWI317653 B TW I317653B TW 091134339 A TW091134339 A TW 091134339A TW 91134339 A TW91134339 A TW 91134339A TW I317653 B TWI317653 B TW I317653B
Authority
TW
Taiwan
Prior art keywords
centrifugation
centrifuge
particles
scalable
product during
Prior art date
Application number
TW091134339A
Other languages
English (en)
Other versions
TW200300706A (en
Inventor
Sandra Patricia Merino
Steven J Dalessio
Robin Roy Louis Rudy Otten
Original Assignee
Alfa Wasserman Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alfa Wasserman Inc filed Critical Alfa Wasserman Inc
Publication of TW200300706A publication Critical patent/TW200300706A/zh
Application granted granted Critical
Publication of TWI317653B publication Critical patent/TWI317653B/zh

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B5/00—Other centrifuges
    • B04B5/10—Centrifuges combined with other apparatus, e.g. electrostatic separators; Sets or systems of several centrifuges
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B1/00—Centrifuges with rotary bowls provided with solid jackets for separating predominantly liquid mixtures with or without solid particles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B13/00—Control arrangements specially designed for centrifuges; Programme control of centrifuges
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B5/00—Other centrifuges
    • B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0442—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B7/00—Elements of centrifuges
    • B04B7/08—Rotary bowls
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B7/00—Elements of centrifuges
    • B04B7/08—Rotary bowls
    • B04B7/12—Inserts, e.g. armouring plates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B5/00—Other centrifuges
    • B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0442—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • B04B2005/0464—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation with hollow or massive core in centrifuge bowl
TW091134339A 2001-11-27 2002-11-26 Centrifuge with removable core for scalable centrifugation, and method for achieving linear separation of particles of a product during centrifugation TWI317653B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/995,054 US20030114289A1 (en) 2001-11-27 2001-11-27 Centrifuge with removable core for scalable centrifugation

Publications (2)

Publication Number Publication Date
TW200300706A TW200300706A (en) 2003-06-16
TWI317653B true TWI317653B (en) 2009-12-01

Family

ID=25541334

Family Applications (1)

Application Number Title Priority Date Filing Date
TW091134339A TWI317653B (en) 2001-11-27 2002-11-26 Centrifuge with removable core for scalable centrifugation, and method for achieving linear separation of particles of a product during centrifugation

Country Status (9)

Country Link
US (5) US20030114289A1 (zh)
EP (2) EP1450961B1 (zh)
AU (1) AU2002362023A1 (zh)
CA (2) CA2821623C (zh)
IL (1) IL162186A0 (zh)
NZ (3) NZ556344A (zh)
SG (2) SG156518A1 (zh)
TW (1) TWI317653B (zh)
WO (1) WO2003045568A1 (zh)

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US20030114289A1 (en) * 2001-11-27 2003-06-19 Merino Sandra Patricia Centrifuge with removable core for scalable centrifugation
US7479123B2 (en) 2002-03-04 2009-01-20 Therakos, Inc. Method for collecting a desired blood component and performing a photopheresis treatment
US7211037B2 (en) 2002-03-04 2007-05-01 Therakos, Inc. Apparatus for the continuous separation of biological fluids into components and method of using same
JP4111048B2 (ja) * 2003-04-28 2008-07-02 日立工機株式会社 連続遠心分離機
US7396324B2 (en) * 2003-10-17 2008-07-08 Hitachi Koki Co., Ltd. Centrifugal separator with first and second control panels
JP2008542015A (ja) * 2005-06-03 2008-11-27 アルファ ワッサーマン インコーポレイテッド 遠心分離機用ロータ及びその使用方法
CA2620666C (en) 2005-12-09 2014-04-01 Alfa Wassermann, Inc. Automated fraction collection system
WO2008122026A1 (en) * 2007-04-02 2008-10-09 Mark Allen Systems, devices, and methods for reaction and/or separation
JP4771294B2 (ja) * 2007-05-31 2011-09-14 日立工機株式会社 遠心分離機
FR2918074B1 (fr) * 2007-06-27 2009-10-09 Sanofi Pasteur Procede de purification d'une suspension virale.
TWI414364B (zh) 2007-12-21 2013-11-11 Alfa Wassermann Inc 連續流超離心系統
US8099430B2 (en) 2008-12-18 2012-01-17 International Business Machines Corporation Computer method and apparatus of information management and navigation
JP5105313B2 (ja) * 2008-09-25 2012-12-26 日立工機株式会社 遠心分離機
US9186668B1 (en) 2010-06-04 2015-11-17 Sandia Corporation Microfluidic devices, systems, and methods for quantifying particles using centrifugal force
US8962346B2 (en) 2010-07-08 2015-02-24 Sandia Corporation Devices, systems, and methods for conducting assays with improved sensitivity using sedimentation
US8945914B1 (en) * 2010-07-08 2015-02-03 Sandia Corporation Devices, systems, and methods for conducting sandwich assays using sedimentation
US9795961B1 (en) 2010-07-08 2017-10-24 National Technology & Engineering Solutions Of Sandia, Llc Devices, systems, and methods for detecting nucleic acids using sedimentation
US9244065B1 (en) 2012-03-16 2016-01-26 Sandia Corporation Systems, devices, and methods for agglutination assays using sedimentation
US9903001B1 (en) 2012-07-19 2018-02-27 National Technology & Engineering Solutions Of Sandia, Llc Quantitative detection of pathogens in centrifugal microfluidic disks
US9304128B1 (en) 2013-02-01 2016-04-05 Sandia Corporation Toxin activity assays, devices, methods and systems therefor
US20140274649A1 (en) * 2013-03-14 2014-09-18 Sean Kerr Bone Marrow Concentrator
US9500579B1 (en) 2013-05-01 2016-11-22 Sandia Corporation System and method for detecting components of a mixture including tooth elements for alignment
AU2013206123B2 (en) * 2013-05-31 2018-08-09 Watanabe Oyster Laboratory Co., Ltd. Method of extracting and manufacturing oyster meat extract using continuous centrifuge
US9803238B1 (en) 2013-11-26 2017-10-31 National Technology & Engineering Solutions Of Sandia, Llc Method and apparatus for purifying nucleic acids and performing polymerase chain reaction assays using an immiscible fluid
CA2878645C (en) 2014-01-22 2017-02-21 Alfa Wassermann, Inc. Centrifugation systems with non-contact seal assemblies
JP6379682B2 (ja) * 2014-05-30 2018-08-29 工機ホールディングス株式会社 遠心機
US9702871B1 (en) 2014-11-18 2017-07-11 National Technology & Engineering Solutions Of Sandia, Llc System and method for detecting components of a mixture including a valving scheme for competition assays
WO2016114992A2 (en) 2015-01-13 2016-07-21 Alfa Wassermann, Inc. Methods of purifying adeno-associated virus (aav) and/or recombinant adeno-associated virus (raav) and gradients and flow-through buffers therefore
DE102015103752A1 (de) * 2015-03-13 2016-09-15 Andreas Hettich Gmbh & Co. Kg Zentrifuge
US10254298B1 (en) 2015-03-25 2019-04-09 National Technology & Engineering Solutions Of Sandia, Llc Detection of metabolites for controlled substances
JP6693152B2 (ja) * 2016-01-29 2020-05-13 工機ホールディングス株式会社 遠心機
CN107398358B (zh) 2016-05-19 2020-04-21 阿尔法韦士曼公司 具有部分通道的离心转子芯
US10406528B1 (en) 2016-08-04 2019-09-10 National Technology & Engineering Solutions Of Sandia, Llc Non-contact temperature control system for microfluidic devices
US10981174B1 (en) 2016-08-04 2021-04-20 National Technology & Engineering Solutions Of Sandia, Llc Protein and nucleic acid detection for microfluidic devices
US10786811B1 (en) 2016-10-24 2020-09-29 National Technology & Engineering Solutions Of Sandia, Llc Detection of active and latent infections with microfluidic devices and systems thereof
DE102020121422A1 (de) 2020-08-14 2022-02-17 Gea Westfalia Separator Group Gmbh Separator
DE102020121419A1 (de) 2020-08-14 2022-02-17 Gea Westfalia Separator Group Gmbh Separator
DE102020121420A1 (de) 2020-08-14 2022-02-17 Gea Westfalia Separator Group Gmbh Separator
JP2023548067A (ja) 2020-11-02 2023-11-15 バイオマリン ファーマシューティカル インコーポレイテッド アデノ随伴ウイルスを濃縮するためのプロセス
US11459536B1 (en) 2021-07-26 2022-10-04 Shanghai Longevity Co., Ltd. Closed cell culturing and harvesting system
EP4397414A1 (en) * 2021-08-31 2024-07-10 Eppendorf Himac Technologies Co., Ltd. Rotor and centrifuge using same

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US446248A (en) * 1891-02-10 Milk testing and separating machine
US3073517A (en) * 1959-04-07 1963-01-15 Beckman Instruments Inc Continuous flow centrifuge apparatus and rotor therefor
US3114289A (en) 1962-07-12 1963-12-17 William E Aulabaugh Muzzle brake
US3288360A (en) * 1964-06-16 1966-11-29 Edwin F Babelay Liquid centrifuge core
US3456876A (en) * 1966-03-23 1969-07-22 Beckman Instruments Inc Apparatus and articles for increasing the rate of particle separation and removal
US3446248A (en) * 1967-06-20 1969-05-27 Resistoflex Corp Reinforced hose
US3430849A (en) * 1967-08-01 1969-03-04 Atomic Energy Commission Liquid centrifuge for large-scale virus separation
US3899128A (en) * 1968-08-23 1975-08-12 Int Equipment Co Zonal centrifuge rotors
US3536253A (en) * 1969-02-24 1970-10-27 Atomic Energy Commission Zonal centrifuge
US3708111A (en) * 1969-12-19 1973-01-02 P Sheeler Apparatus and method for gradient zonal centrifugation
US3730422A (en) * 1971-05-25 1973-05-01 Atomic Energy Commission Continuous flow centrifuge with means for reducing pressure drop
DE3771148D1 (de) * 1986-07-22 1991-08-08 Haemonetics Corp Zentrifugengehaeuse oder rotor fuer plasmapherese.
WO2002082079A1 (en) 2001-03-22 2002-10-17 The State Of Oregon, Acting By And Through The State Board Of Higher Education On Behalf Of The University Of Oregon Enhanced protein separation and analysis
US20030114289A1 (en) * 2001-11-27 2003-06-19 Merino Sandra Patricia Centrifuge with removable core for scalable centrifugation

Also Published As

Publication number Publication date
US7862494B2 (en) 2011-01-04
US20110136648A1 (en) 2011-06-09
IL162186A0 (en) 2005-11-20
US7837609B2 (en) 2010-11-23
NZ556344A (en) 2009-09-25
EP1450961A1 (en) 2004-09-01
NZ533241A (en) 2006-05-26
CA2821623C (en) 2015-03-17
CA2821623A1 (en) 2003-06-05
EP2474363A1 (en) 2012-07-11
AU2002362023A1 (en) 2003-06-10
CA2468337A1 (en) 2003-06-05
EP2474363B1 (en) 2015-02-25
EP1450961A4 (en) 2009-11-25
SG156519A1 (en) 2009-11-26
TW200300706A (en) 2003-06-16
EP1450961B1 (en) 2015-02-25
US20050176571A1 (en) 2005-08-11
US20030114289A1 (en) 2003-06-19
WO2003045568A1 (en) 2003-06-05
NZ544529A (en) 2008-03-28
US20050215410A1 (en) 2005-09-29
CA2468337C (en) 2013-10-01
SG156518A1 (en) 2009-11-26
US20100041536A9 (en) 2010-02-18
US20060258524A1 (en) 2006-11-16
US9050609B2 (en) 2015-06-09

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MM4A Annulment or lapse of patent due to non-payment of fees