TWI295374B - - Google Patents
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- Publication number
- TWI295374B TWI295374B TW95111331A TW95111331A TWI295374B TW I295374 B TWI295374 B TW I295374B TW 95111331 A TW95111331 A TW 95111331A TW 95111331 A TW95111331 A TW 95111331A TW I295374 B TWI295374 B TW I295374B
- Authority
- TW
- Taiwan
- Prior art keywords
- chromium
- trodat
- column
- dmga
- sample
- Prior art date
Links
- 238000004458 analytical method Methods 0.000 claims description 36
- WEVYAHXRMPXWCK-UHFFFAOYSA-N Acetonitrile Chemical compound CC#N WEVYAHXRMPXWCK-UHFFFAOYSA-N 0.000 claims description 27
- 239000000243 solution Substances 0.000 claims description 27
- 238000004128 high performance liquid chromatography Methods 0.000 claims description 10
- 238000000034 method Methods 0.000 claims description 9
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims description 6
- 229910052708 sodium Inorganic materials 0.000 claims description 6
- 239000011734 sodium Substances 0.000 claims description 6
- 102000006441 Dopamine Plasma Membrane Transport Proteins Human genes 0.000 claims description 5
- 108010044266 Dopamine Plasma Membrane Transport Proteins Proteins 0.000 claims description 5
- 239000000203 mixture Substances 0.000 claims description 4
- 239000003643 water by type Substances 0.000 claims description 4
- 239000002872 contrast media Substances 0.000 claims description 3
- 238000011160 research Methods 0.000 claims description 3
- 238000002360 preparation method Methods 0.000 claims description 2
- DUHQIGLHYXLKAE-UHFFFAOYSA-N 3,3-dimethylglutaric acid Chemical compound OC(=O)CC(C)(C)CC(O)=O DUHQIGLHYXLKAE-UHFFFAOYSA-N 0.000 claims 2
- VYFYYTLLBUKUHU-UHFFFAOYSA-N dopamine Chemical compound NCCC1=CC=C(O)C(O)=C1 VYFYYTLLBUKUHU-UHFFFAOYSA-N 0.000 claims 2
- 239000000126 substance Substances 0.000 claims 2
- RTBFRGCFXZNCOE-UHFFFAOYSA-N 1-methylsulfonylpiperidin-4-one Chemical compound CS(=O)(=O)N1CCC(=O)CC1 RTBFRGCFXZNCOE-UHFFFAOYSA-N 0.000 claims 1
- 241000283690 Bos taurus Species 0.000 claims 1
- 108010078791 Carrier Proteins Proteins 0.000 claims 1
- JFCQEDHGNNZCLN-UHFFFAOYSA-N anhydrous glutaric acid Natural products OC(=O)CCCC(O)=O JFCQEDHGNNZCLN-UHFFFAOYSA-N 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 125000000118 dimethyl group Chemical group [H]C([H])([H])* 0.000 claims 1
- 229960003638 dopamine Drugs 0.000 claims 1
- 239000008354 sodium chloride injection Substances 0.000 claims 1
- 238000012360 testing method Methods 0.000 description 32
- 230000014759 maintenance of location Effects 0.000 description 22
- 239000012535 impurity Substances 0.000 description 14
- 238000004587 chromatography analysis Methods 0.000 description 9
- 238000010586 diagram Methods 0.000 description 9
- HZLFSOZSLFKJKA-JSXRDJHFSA-N 2-[2-[[(1s,3s,4r,5r)-3-(4-chlorophenyl)-8-methyl-8-azabicyclo[3.2.1]octan-4-yl]methyl-(2-sulfanylethyl)amino]ethylamino]ethanethiol Chemical compound C1([C@@H]2[C@H](CN(CCS)CCNCCS)[C@H]3CC[C@@H](C2)N3C)=CC=C(Cl)C=C1 HZLFSOZSLFKJKA-JSXRDJHFSA-N 0.000 description 6
- 238000004925 denaturation Methods 0.000 description 6
- 230000036425 denaturation Effects 0.000 description 6
- VYZAMTAEIAYCRO-UHFFFAOYSA-N Chromium Chemical compound [Cr] VYZAMTAEIAYCRO-UHFFFAOYSA-N 0.000 description 5
- 229910052804 chromium Inorganic materials 0.000 description 5
- 239000011651 chromium Substances 0.000 description 5
- 239000007788 liquid Substances 0.000 description 3
- 230000005855 radiation Effects 0.000 description 3
- 238000011084 recovery Methods 0.000 description 3
- 101001068640 Nicotiana tabacum Basic form of pathogenesis-related protein 1 Proteins 0.000 description 2
- CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 description 2
- 238000012790 confirmation Methods 0.000 description 2
- 230000007850 degeneration Effects 0.000 description 2
- 238000000926 separation method Methods 0.000 description 2
- 230000003321 amplification Effects 0.000 description 1
- 238000004364 calculation method Methods 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000003199 nucleic acid amplification method Methods 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 230000037452 priming Effects 0.000 description 1
- 230000000750 progressive effect Effects 0.000 description 1
- 238000013094 purity test Methods 0.000 description 1
- 238000003908 quality control method Methods 0.000 description 1
- 229910000029 sodium carbonate Inorganic materials 0.000 description 1
- 238000010200 validation analysis Methods 0.000 description 1
Landscapes
- Sampling And Sample Adjustment (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| TW095111331A TW200736608A (en) | 2006-03-30 | 2006-03-30 | Purity analysis method of radioanalytical chemistry of a technetium-99m-TRODAT-1 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| TW095111331A TW200736608A (en) | 2006-03-30 | 2006-03-30 | Purity analysis method of radioanalytical chemistry of a technetium-99m-TRODAT-1 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TW200736608A TW200736608A (en) | 2007-10-01 |
| TWI295374B true TWI295374B (enExample) | 2008-04-01 |
Family
ID=45068418
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW095111331A TW200736608A (en) | 2006-03-30 | 2006-03-30 | Purity analysis method of radioanalytical chemistry of a technetium-99m-TRODAT-1 |
Country Status (1)
| Country | Link |
|---|---|
| TW (1) | TW200736608A (enExample) |
-
2006
- 2006-03-30 TW TW095111331A patent/TW200736608A/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| TW200736608A (en) | 2007-10-01 |
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