1282740 :/1-. •^•-'.-Nv-^f-·^·：··-·^»·,^ 玖.、發明說阻 【發明所屬之技術領域】 本發明係關於一種使用感良好的液狀化粧料，其即使 在做爲美白成分之水溶性L-抗壞血酸衍生物存在下，依然 保濕效果高且水嫩（young and fresh或fresh、juicy)並且無黏 腻感（sticy、tacky、viscous) 0 【先前技術】 一直以來，水溶性抗壞血酸衍生物因美白效果良好， 被配合於許多化粧料中。但，若化粧料中含有多量水溶个生 L-抗壞血酸衍生物則會伴隨有獨特之黏腻感或皮膜感，使 得很難得到良好使用感。爲了滿足使用感，有使用配合$ 溶性高分子或鱲、粉末等高分子量之物質以對抗黏腻感之 方法、或配合油等軟化劑以抑制黏腻感之方法等。比如有 ，配合糊精脂肪酸酯者（專利文獻1參照）、配合多孔質粉末 及/或吸水性粉末者（專利文獻2參照）、配合水溶性聚醚二 甲基聚矽氧烷（專利文獻3參照）、配合矽酮油（專利文獻4 參照）等者。 [專利文獻1]日本專利特開2002-020529號公報（申請專 利範圍、發明所屬之技術領域） [專利文獻2]特開2002-104919號公報（申請專利範圍、 發明所屬之技術領域） [專利文獻3]特開2000-290128號公報（申請專利範圍、 發明所屬之技術領域） [專利文獻4]特開2001-151623號公報（第2頁，右上第 6行至第16行） 1282740 【發明內容】 發明租欲解決之誤顆 但，該種方法要用於有流動性之液狀化粧料並實現水 嫩且不會有黏腻感在技術上有困難。而本發明係在這種現 狀下所產生的，即，本發明係關於一種液狀化粧料，其含 有水溶性L-抗壞血酸衍生物且使用感良好。 用以解_決課題之手段 本發明者爲解決上述課題，專心硏究的結果，發現含 有水溶性L-抗壞血酸衍生物之液狀化粧料中，若使含有聚 環氧丙烷二甘油及帶有3個以上羥基之多元醇，則可具有 良好使用感，並完成本發明。 即，本發明係關於含以下所示成分（a)〜(c)爲必要成分 之液狀化粧料。 (a) 聚環氧丙烷二甘油 (b) 水溶性L-抗壞血酸衍生物0.5〜5質量％ (c) 帶有3個以上羥基之多元醇 再者，係關於含有成分⑷乙醇之液狀化粧料，又，係 關於特徵爲成分（a)與成分（b)之含有質量比爲1:1〇〜i〇:i之 液狀化粧料。 【實施方式】 以下，說明本發明之構成。 本發明所使用之成分U)聚環氧丙烷二甘油係爲用以抑 制成分（b)水溶性L-抗壞血酸衍生物之黏腻感。成分（a)比 如有以下述通式（1)所示構造式者。成分（a)係在二甘油上加 1282740 成聚合環氧丙烷之化合物，環氧丙烷之平均加成莫耳數不 特別限定，但以二甘油每1莫爾帶有5〜20莫耳平均加成莫 耳數者對黏腻之抑制效果較佳。該等聚環氧丙烷二甘油可 依需求使用1種或組合2種以上使用。該等成分（a)之市售 品有Savondol GP-9(日本油脂）、普立司托魯DGP-09(米優喜 油脂）、SY-DP9、SY-DP14(以上，阪本藥品工業）等。 通式（1) H(0CHCH 丄-O-CHrCH-CHrO-CHrCH-CH-CHrCKCHCHO〉#1282740 :/1-. •^•-'.-Nv-^f-·^·:····^»····································· A good liquid cosmetic which has a high moisturizing effect and a moisturizing effect (young and fresh or fresh, juicy) and no sticky feeling (sticy, even in the presence of a water-soluble L-ascorbic acid derivative as a whitening ingredient. Tacky, viscous) 0 [Prior Art] Water-soluble ascorbic acid derivatives have been used in many cosmetic materials because of their good whitening effect. However, if the cosmetic contains a large amount of water-soluble L-ascorbic acid derivative, it will be accompanied by a unique sticky feeling or a feeling of film, making it difficult to obtain a good feeling of use. In order to satisfy the feeling of use, there is a method of using a high molecular weight substance such as a soluble polymer, a hydrazine or a powder to suppress a sticky feeling, or a method of blending a softening agent such as oil to suppress a sticky feeling. For example, those who have a dextrin fatty acid ester (refer to Patent Document 1), a porous powder and/or a water-absorbent powder (refer to Patent Document 2), and a water-soluble polyether dimethyl polyoxyalkylene (Patent Literature) 3)), and an anthrone oil (refer to Patent Document 4). [Patent Document 1] Japanese Patent Laid-Open Publication No. 2002-020529 (Patent Document No. JP-A-2002-104919) (Application No. 2002-104919) Japanese Laid-Open Patent Publication No. 2000-290128 (Patent Document No. JP-A No. 2001-151623 (page 2, upper right sixth line to the 16th line) 1282740 Contents] Invented by renting a desire to solve the problem, however, this method is technically difficult to use for a liquid liquid cosmetic material and to achieve a tender and non-sticky feeling. While the present invention has been made in such a state, the present invention relates to a liquid cosmetic containing a water-soluble L-ascorbic acid derivative and having a good feeling in use. Means for Solving the Problem The present inventors have found that a liquid cosmetic containing a water-soluble L-ascorbic acid derivative contains polypropylene oxide diglycerin and has a solution in order to solve the above problems. The polyol having three or more hydroxyl groups can have a good feeling of use and complete the present invention. That is, the present invention relates to a liquid cosmetic containing the components (a) to (c) shown below as essential components. (a) Polypropylene oxide diglycerin (b) Water-soluble L-ascorbic acid derivative 0.5 to 5% by mass (c) Polyol having three or more hydroxyl groups, and liquid cosmetic containing the component (4) ethanol Further, it is a liquid cosmetic which is characterized in that the mass ratio of the component (a) to the component (b) is 1:1〇~i〇:i. [Embodiment] Hereinafter, the configuration of the present invention will be described. The component U) used in the present invention is a polypropylene oxide diglycerin for suppressing the sticky feeling of the component (b) water-soluble L-ascorbic acid derivative. The component (a) has a structural formula represented by the following formula (1). The component (a) is a compound of 1,282,740 polymerized propylene oxide added to the diglycerin, and the average addition mole number of the propylene oxide is not particularly limited, but the average amount of the diglycerin is 1 to 20 mol per 1 m. Those who have a molar number have a better inhibitory effect on stickiness. These polypropylene oxide diglycerides may be used singly or in combination of two or more kinds as needed. Commercially available products of these components (a) include Savondol GP-9 (Japanese fats and oils), Priestor DGP-09 (Miyouxi oil), SY-DP9, SY-DP14 (above, Sakamoto Pharmaceutical Industries). General formula (1) H(0CHCH 丄-O-CHrCH-CHrO-CHrCH-CH-CHrCKCHCHO>#
(m+n+o+p = 5 〜20(較佳例）） 本發明中所使用成分（a)之含量較佳爲對液狀化粧料總 質量爲0.001〜30質量％(以下，單以「％」表示，又，在本 說明書中，「質量％」與「重量％」爲同義），更佳爲 0.1〜10%。若在此範圍內，可得到水嫩且保溼感良好之液狀 化粧料。 本發明所使用之成分（b)水溶性L-抗壞血酸衍生物係 爲用以賦予化粧料美白效果，且只要是水溶性者則不特別 限定。若具體例示，比如有L-抗壞血酸鈉、L-抗壞血酸鉀 、L-抗壞血酸鎂、L-抗壞血酸磷酸鈉、L-抗壞血酸磷酸鎂、 L-抗壞血酸磷酸鈣、L-抗壞血酸硫酸鈉、L-抗壞血酸硫酸鎂 1282740 、L-抗壞血酸硫酸鈣等。其中，以藥劑本身安定性或配合 時之簡便性的觀點，較佳者比如有，L-抗壞血酸磷酸鎂、 L-抗壞血酸磷酸鈉、L-抗壞血酸硫酸鈉等。該等可依需求 使用1種或組合2種以上使用。 本發明中所使用成分（b)之含量較佳爲對液狀化粧料總 質量爲0.5〜5質量％，更佳爲1〜3%。若在此範圍內，則可 得到美白效果良好，且無黏腻感且水嫩且保溼感良好之液 狀化粧料。 本發明所使用之成分（c)帶有3個以上羥基之多元醇係 爲用以賦予化粧料保溼效果，分子內帶有3個以上羥基之 多元醇比如有，甘油、二甘油、三甘油、四甘油等多甘油 、麥芽糖、麥芽糖醇、蔗糖、果糖、木糖醇、山梨糖醇、 麥芽三糖、赤蘚醇，其他還有聚乙二醇衍生物、葡萄糖衍 生物等。其中，由保溼效果之觀點，以分子內帶有3〜10個 左右羥基之多元醇爲較佳。該等分子內帶有3個以上羥基 之多元醇可依需求使用1種或組合2種以上使用。 本發明中所使用成分（c)之含量較佳爲對液狀化粧料總 質量爲0.001〜30質量％，更佳爲〇.1〜1〇%。若在此範圍內， 則特別可期待有足夠的保溼感。 本發明之液狀化粧料藉含有上述（a)〜(c)之成分可得到 使用感良好之液狀化粧料，藉進一步含有成分（d)乙醇，可 得到更能增進水嫩之使用感，並且更能抑制黏腻感之液狀 化粧料。成分(d)之含量較佳爲對液狀化粧料總質量爲丨〜％ 質量％，更佳爲3〜20%。 1282740 再者，若上述成分（a)與成分（b)之含有質量比（a):(b)在 1:10〜10:1，更佳爲1:5〜5:1之範圍時，黏腻感可更被抑制， 而使本發明之效果更爲顯著。（又，在本說明書中，「質量 比」與「重量比」爲同義） 又，本發明之液狀化粧料其液狀在一般狀態下使用時 爲有流動性，在20°C之黏度値爲5〜40000mPa· s之範圍內 。若較佳在10〜20000mPa · s之範圍，更佳在10〜5000mPa · s之範圍，則可期待成爲使用性更好的液狀化粧料。 本發明之液狀化粧料其調製方法不特別限定，可依化 粧料之處方特性適當選擇。作爲例示，比如有將醇中溶解 有界面活性劑、油劑等而成者分散於水系中以調製之凝縮 法、使用高壓均質機等機械力以調製之方法等。 本發明之液狀化粧料除化粧料，亦可利用於準醫藥品 、外用醫藥品等。化粧料比如可作成化粧水、美容液、芳 香用組成物等各種液狀製劑。再者，本液狀化粧料亦可用 周知之方法作成噴劑、慕斯等製劑，又，亦可含浸於不織 布等，製成片狀製劑。 本發明之液狀化粧料中只要使在不損害本發明效果之 範圍內可含有普通化粧料或準醫藥品、外用醫藥品等領域 所含有之成分。比如有，界面活性劑、油劑、保濕劑、高 分子類、紫外線吸收劑、多價螯合劑、中和劑、pH調整劑 、抗氧化劑、抗菌劑、防腐劑、色素、粉體、顏料、香料 、藥效劑等，可依需要適當使用。 1282740 (實施例） 以下舉實施例更詳細說明本發明，但並不因此而限定 本發明。 (實施例1〜12及比較例1〜5;化粧水） 製造表1(實施例）及表2(比較例）所示組成之化粧水， 並以無黏腻感度、水嫩度、保濕感之3個評價項目作使用 感之評價。 表1 成分 實施例(％) 1 2 3 4 5 6 7 8 9 10 11 12 1 聚環氧丙烷(9)二甘油 1 1 1 10 0.3 10 1 0.5 1 1 10 2 聚環氧丙院(14)二甘油 - - 3 甘油 5 • • 5 5 5 5 0.5 5 5 5 5 4 麥芽糖醇 - 5 - 5 三甘油 - • 5 - 6 L-抗壞血酸磷酸鎂 3 3 3 3 3 1 1 0.5 3 3 • - 7 L-抗壞血酸磷酸鈉 - 3 1 8 檸檬酸鈉 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 9 純水 殘量 殘量 殘量 殘量 殘量 殘量 殘量 殘量 殘量 殘量 殘量 殘量 10 乙醇 10 10 10 10 10 10 10 10 10 - 10 10 11 二丙二醇 10 • - 12 聚環氧乙烷(60)硬化篦麻油 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 成分⑻/成分(b) 1/3 1/3 1/3 10/3 1/10 10/1 1/1 1/1 1/3 1/3 1/3 10/1 判定 無黏腻感度 ◎ ◎ 〇 ◎ 〇 ◎ ◎ ◎ ◎ 〇 ◎ ◎ 水嫩度 ◎ ◎ ◎ 〇 〇 〇 ◎ ◎ ◎ 〇 ◎ 〇 保濕感 ◎ ◎ ◎ ◎ 〇 ◎ ◎ 〇 ◎ ◎ ◎ ◎ Μ 1282740 表2 成分 嫌例(％) 1 2 3 4 5 1 聚環氧丙烷(9)二甘油 - • 1 2 6 2 聚環氧丙院(14)二甘油 - - - - 3 甘油 - 5 - 5 5 4 麥芽糖醇 - - - - • 5 三甘油 - • _ - 6 L-抗壞血酸磷酸鎂 3 3 3 6 6 7 L-抗壞血酸磷酸鈉 - 雜 - • 8 檸檬酸鈉 0.1 0.1 0.1 0.1 0.1 9 純水 殘量 殘量 殘量 殘量 殘量 10 乙醇 10 10 10 10 10 11 二丙二醇 - - - - - 12 聚環氧乙烷(60)硬化篦麻油 0.1 0.1 0.1 0.1 0.1 成分⑻/成分(b) • - 1/3 1/3 1/1 判 定 無黏腻感度 X X 〇 X Δ 水嫩度 X X X Δ X 保濕感 X 〇 X 〇 〇(m+n+o+p = 5 to 20 (preferred)) The content of the component (a) used in the present invention is preferably 0.001 to 30% by mass based on the total mass of the liquid cosmetic (hereinafter, "%" indicates that, in this specification, "% by mass" is synonymous with "% by weight", and more preferably 0.1 to 10%. Within this range, a liquid cosmetic which is moist and has a good moisturizing feeling can be obtained. The component (b) water-soluble L-ascorbic acid derivative used in the present invention is a whitening effect for imparting a cosmetic, and is not particularly limited as long as it is water-soluble. Specific examples include, for example, sodium L-ascorbate, potassium L-ascorbate, magnesium L-ascorbate, sodium L-ascorbyl phosphate, magnesium L-ascorbyl phosphate, calcium L-ascorbyl phosphate, sodium L-ascorbate, magnesium sulfate L-ascorbate 1282740, L-ascorbyl sulfate, etc. Among them, preferred are, for example, L-ascorbyl magnesium phosphate, sodium L-ascorbyl phosphate, sodium L-ascorbate or the like from the viewpoint of stability of the drug itself or ease of compounding. These may be used singly or in combination of two or more kinds as needed. The content of the component (b) used in the present invention is preferably from 0.5 to 5% by mass, more preferably from 1 to 3%, based on the total mass of the liquid cosmetic. If it is within this range, a liquid cosmetic which has a good whitening effect, is not sticky, and is moist and has a good moisturizing feeling can be obtained. The component (c) used in the present invention is a polyol having three or more hydroxyl groups, which is a polyol for imparting a moisturizing effect to a cosmetic, and a polyhydric alcohol having three or more hydroxyl groups in the molecule, such as glycerin, diglycerin or triglycerin. Polyglycerol, maltose, maltitol, sucrose, fructose, xylitol, sorbitol, maltotriose, erythritol, and other polyethylene glycol derivatives, glucose derivatives, and the like. Among them, from the viewpoint of the moisturizing effect, a polyol having 3 to 10 or so hydroxyl groups in the molecule is preferred. The polyol having three or more hydroxyl groups in the molecule may be used singly or in combination of two or more kinds as needed. The content of the component (c) used in the present invention is preferably 0.001 to 30% by mass, more preferably 〇1 to 1% by mass based on the total mass of the liquid cosmetic. If it is in this range, it is especially desirable to have a sufficient moisturizing feeling. The liquid cosmetic of the present invention can provide a liquid cosmetic having a good feeling of use by containing the components (a) to (c), and further contains the component (d) ethanol to obtain a feeling of use which is more prone to moisturization. And it can suppress the liquid makeup of sticky feeling. The content of the component (d) is preferably 丨% to % by mass, more preferably 3 to 20%, based on the total mass of the liquid cosmetic. 1282740 Further, if the mass ratio (a) of the component (a) to the component (b) is (b) in the range of 1:10 to 10:1, more preferably 1:5 to 5:1, the viscosity is The greasy feeling can be more suppressed, and the effect of the present invention is more remarkable. (In addition, in the present specification, the "mass ratio" is synonymous with the "weight ratio"). Further, the liquid cosmetic of the present invention has fluidity when used in a normal state, and has a viscosity at 20 ° C. It is in the range of 5 to 40000 mPa·s. If it is preferably in the range of 10 to 20,000 mPa·s, more preferably in the range of 10 to 5,000 mPa·s, it is expected to be a liquid cosmetic which is more usable. The preparation method of the liquid cosmetic of the present invention is not particularly limited, and can be appropriately selected depending on the characteristics of the cosmetic material. For example, a method in which a surfactant, an oil agent, or the like is dissolved in an alcohol to disperse it in a water system to prepare a condensation method, or a mechanical force such as a high-pressure homogenizer is used to prepare the sample. The liquid cosmetic of the present invention can be used for quasi-drugs and external pharmaceuticals in addition to cosmetics. The cosmetic material can be used, for example, as a liquid preparation such as a lotion, a beauty liquid, or a fragrance composition. Further, the liquid cosmetic may be prepared into a spray, a mousse or the like by a known method, or may be impregnated with a non-woven fabric or the like to prepare a sheet-like preparation. The liquid cosmetic of the present invention may contain components contained in the fields of ordinary cosmetics, quasi-drugs, and external medicines as long as the effects of the present invention are not impaired. For example, surfactants, oils, humectants, polymers, UV absorbers, sequestrants, neutralizers, pH adjusters, antioxidants, antibacterial agents, preservatives, pigments, powders, pigments, Spices, medicinal agents, etc., can be used as needed. 1282740 (Embodiment) Hereinafter, the present invention will be described in more detail by way of examples, but the invention is not limited thereto. (Examples 1 to 12 and Comparative Examples 1 to 5; lotion) The lotion having the composition shown in Table 1 (Example) and Table 2 (Comparative Example) was produced, and was free from sticky feeling, tenderness, and moisturizing feeling. The evaluation items of the three evaluation items are evaluated. Table 1 Ingredient Example (%) 1 2 3 4 5 6 7 8 9 10 11 12 1 Polypropylene oxide (9) Diglycerin 1 1 1 10 0.3 10 1 0.5 1 1 10 2 Polyepoxypropyl (1) Diglycerin - - 3 Glycerol 5 • • 5 5 5 5 0.5 5 5 5 5 4 Maltitol - 5 - 5 Triglycerol - • 5 - 6 L-Ascorbyl Magnesium Phosphate 3 3 3 3 3 1 1 0.5 3 3 • - 7 L-ascorbyl phosphate - 3 1 8 Sodium citrate 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 9 Pure water residuals residuals residuals residuals residuals residuals residuals residuals residuals residuals residuals Amount 10 Ethanol 10 10 10 10 10 10 10 10 10 - 10 10 11 Dipropylene glycol 10 • - 12 Polyethylene oxide (60) hardened castor oil 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 Ingredients (8) / ingredients ( b) 1/3 1/3 1/3 10/3 1/10 10/1 1/1 1/1 1/3 1/3 1/3 10/1 Judging no sticky feeling ◎ ◎ 〇 ◎ 〇 ◎ ◎ ◎ ◎ 〇 ◎ ◎ Moisture ◎ ◎ ◎ 〇〇〇 ◎ ◎ ◎ 〇 ◎ 〇 〇 ◎ ◎ ◎ ◎ ◎ ◎ ◎ ◎ ◎ ◎ ◎ ◎ Μ 1282740 Table 2 Suspect (%) 1 2 3 4 5 1 Polypropylene oxide (9) Diglycerin - • 1 2 6 2 Polyethylene oxide (14) Diglycerin - - - - 3 Glycerol - 5 - 5 5 4 Maltitol - - - - • 5 Triglycerol - • _ - 6 L-ascorbyl magnesium phosphate 3 3 3 6 6 7 L-ascorbyl phosphate - miscellaneous - • 8 Sodium citrate 0.1 0.1 0.1 0.1 0.1 9 Pure water residual residue Residual amount 10 Ethanol 10 10 10 10 10 11 Dipropylene glycol - - - - - 12 Polyethylene oxide (60) Hardened castor oil 0.1 0.1 0.1 0.1 0.1 Ingredient (8) / Ingredient (b) • - 1/3 1 /3 1/1 Judging no sticky feeling XX 〇X Δ Moisture XXX Δ X Moisturizing feeling X 〇X 〇〇
11 1282740 (製造方法） A:將成分1〜9於40°C下混合並溶解。 B:將成分10〜12於室溫下混合並溶解。 C:將A添加至B中並混合，以得到化粧水。 (使用感之判定方法） 以10名專門之評價委員，對塗佈在皮膚時之使用性( 無黏腻感度、水嫩度、保濕感)依下述評價基準進行5階段 評價，再由其平均點依下述判定基準作判定。 [評價基準] 5點：非常良好 4點：良好 3點：普通 2點：不良 1點：非常不良 [判定基準] ◎:平均點4.5點以上 〇：平均點3.5點以上未滿4.5點 △:平均點2.5點以上未滿3.5點 X:平均點未滿2.5點 依以上評價方法所得到之結果倂列於表1、表2。 如表1之結果可了解，本發明之實施例1~12之化粧水 即使配合水溶性L-抗壞血酸磷酸鎂、水溶性L-抗壞血酸磷 酸鈉，使用感仍然良好。相對於此，表2之比較例1〜5中 ，無法得到可滿足所有項目者。11 1282740 (Manufacturing Method) A: Components 1 to 9 were mixed and dissolved at 40 °C. B: Components 10 to 12 were mixed and dissolved at room temperature. C: A was added to B and mixed to obtain a lotion. (Method of judging the feeling of use) The evaluation of the application to the skin (no stickiness, water tenderness, moisturizing feeling) was evaluated in five stages according to the following evaluation criteria, and the evaluation was carried out by the ten special evaluation committees. The average point is judged based on the following criteria. [Evaluation Criteria] 5 points: Very good 4 points: Good 3 points: Normal 2 points: 1 point bad: Very bad [Criteria for judgment] ◎: Average point of 4.5 points or more 〇: Average point of 3.5 points or more and less than 4.5 points △: The average point is 2.5 points or more and less than 3.5 points. X: The average point is less than 2.5 points. The results obtained by the above evaluation methods are listed in Tables 1 and 2. As is apparent from the results of Table 1, the lotions of Examples 1 to 12 of the present invention were excellent in use even when combined with water-soluble L-ascorbyl magnesium phosphate and water-soluble L-ascorbyl phosphate. On the other hand, in Comparative Examples 1 to 5 of Table 2, those who could satisfy all the items could not be obtained.
12 1282740 實施例13:化粧水 (成分） （％) 1. 環氧乙烷（60)硬化篦麻油 0.3 2. 油溶性甘草萃取物 0.01 3. 維生素E菸鹼酸 0.01 4. 乙醇 5.0 5. 甘油 10.0 6. 環氧乙烷（10)甲基配糖體 2.0 7. L-抗壞血酸磷酸鎂 3.0 8. 環氧丙烷（9)二甘油 0.5 9. 檸檬酸 0.01 10. 檸檬酸鈉 0.03 11. 甘菊萃取液 0.01 12. 薰衣草水 0.01 13丄-精胺酸 0.1 14. 防腐劑 適量 15. 純水 殘量 (製造方法） A:將成分1〜4於40°C下混合並溶解。 B:將成分5〜15於室溫下混合並溶解。 C:將A添加至B中並混合，以得到化粧水。 實施例13之化粧水具有充分的保濕感，少有水溶性L-抗壞血酸磷酸鎂之黏腻感，且爲水嫩之化粧水。 13 1282740 實施例14Ί化粧水 (成分） （％) 1. 環氧乙烷（40)異硬脂醚 0.1 2. 環氧乙烷（20)異硬脂醚 0.05 3. 環氧乙烷（6)烷基（C12-18)醚磷酸 0.1 4. 橄欖油 0.2 5. 天然維生素E 0.2 6. 油溶性迷迭香萃取物 0.01 7. 維生素E菸鹼酸 0.01 8. 乙醇 10.0 9. 山梨糖醇 3.0 10. 環氧丙烷（14)二甘油 3.0 11. 檸檬酸鈉 0.5 12. 乙二胺四乙酸二鈉 0.03 13. 薏苡仁萃取液 0.01 14. 甘菊萃取液 0.1 15. L-抗壞血酸磷酸鎂 1.0 16. 焦谷胺酸鈉 0.2 17. 乳酸鈉 0.1 18. 透明質酸鈉水溶液（1%) 2.0 19. 防腐劑 適量 20. 純水 殘量 (製造方法） A:將成分1〜8於40°C下混合並溶解。 B:將成分9〜20於室溫下混合並溶解。 C:將A添加至B中並混合，以得到化粧水。12 1282740 Example 13: Lotion (ingredients) (%) 1. Ethylene oxide (60) hardened castor oil 0.3 2. Oil-soluble licorice extract 0.01 3. Vitamin E nicotinic acid 0.01 4. Ethanol 5.0 5. Glycerin 10.0 6. Ethylene oxide (10) methyl glycoside 2.0 7. L-ascorbyl magnesium phosphate 3.0 8. Propylene oxide (9) diglycerol 0.5 9. Citric acid 0.01 10. Sodium citrate 0.03 11. Chamomile Extract 0.01 12. Lavender water 0.01 13丄-arginine 0.1 14. Preservative amount 15. Pure water residue (manufacturing method) A: Components 1 to 4 were mixed and dissolved at 40 °C. B: Components 5 to 15 were mixed and dissolved at room temperature. C: A was added to B and mixed to obtain a lotion. The lotion of Example 13 has a sufficient moisturizing feeling, and has a sticky feeling of water-soluble L-ascorbyl magnesium phosphate, and is a moisturizing lotion. 13 1282740 Example 14 Ί lotion (ingredients) (%) 1. Ethylene oxide (40) isostearyl ether 0.1 2. Ethylene oxide (20) isostearyl ether 0.05 3. Ethylene oxide (6) Alkyl (C12-18) ether phosphate 0.1 4. Olive oil 0.2 5. Natural vitamin E 0.2 6. Oil-soluble rosemary extract 0.01 7. Vitamin E nicotinic acid 0.01 8. Ethanol 10.0 9. Sorbitol 3.0 10 Propylene oxide (14) diglycerin 3.0 11. Sodium citrate 0.5 12. Disodium edetate 0.03 13. Coix seed extract 0.01 14. Chamomile extract 0.1 15. L-ascorbyl magnesium phosphate 1.0 16. Sodium pyroglutamate 0.2 17. Sodium lactate 0.1 18. Sodium hyaluronate aqueous solution (1%) 2.0 19. Preservative amount 20. Pure water residue (manufacturing method) A: Mix ingredients 1 to 8 at 40 ° C And dissolved. B: Components 9 to 20 were mixed and dissolved at room temperature. C: A was added to B and mixed to obtain a lotion.
14 1282740 實施例14之化粧水，少有水溶性L-抗壞血酸磷酸鎂之 黏腻感，且具有充分的柔軟感，爲經時安定性良好之化粧 水。 實施例15:美容液 (成分） (%) 1.加氫大豆磷脂質 1.0 2.環氧乙烷（10)膽固醇醚 0.03 3.醯基鞘氨醇3 0.1 4.硬脂酸 0.01 5.三-2-乙基己酸甘油 0.05 6.油溶性甘草精 0.01 7.維生素A棕櫚酸酯 0.01 8.二丙二醇 5.0 9.純水 15.0 10. L-抗壞血酸硫酸鈉 1.0 11.檸檬酸鈉 0.05 12.乙醇 3.0 13.溫椁子萃取物 15.0 14.環氧丙烷（9)二甘油 1.0 15.二甘油 5.0 16.咕噸膠1%水溶液 30.0 17.乙醯基谷胺酸 0.3 18.球狀尼龍粉末 1.0 19.防腐劑 適量 20.純水 殘量 1282740 (製造方法） A:將成分1〜8於85°C下混合並溶解。 B:將成分9加熱至85°C並在充分攪拌下加入A。 C:將成分B冷卻並以高壓均質機使微粒子化。 D:將成分10〜20於室溫下混合並溶解。 E:將C添加至D中並混合，以得到美容液。 實施例15之美容液少有水溶性L·抗壞血酸硫酸鈉之黏 腻感，且具有充分的保濕感，爲使用性良好之美容液。 發明之效果 如以上所詳述，本發明之液狀化粧料可一面活用水溶 性L-抗壞血酸衍生物之美白作用，且即使在水溶性L-抗壞 血酸衍生物存在下，使用感依然良好。14 1282740 The lotion of Example 14 has a sticky feeling of water-soluble L-ascorbyl magnesium phosphate and has a sufficient soft feeling, and is a lotion having good stability over time. Example 15: Beauty liquid (ingredient) (%) 1. Hydrogenated soybean phospholipid 1.0 2. Ethylene oxide (10) cholesterol ether 0.03 3. Mercapto sphingosine 3 0.1 4. Stearic acid 0.01 5. 2-ethylhexanoic acid glycerol 0.05 6. Oil-soluble liquorice 0.01 7. Vitamin A palmitate 0.01 8. Dipropylene glycol 5.0 9. Pure water 15.0 10. L-ascorbyl sulfate 1.0 11. Sodium citrate 0.05 12. Ethanol 3.0 13. Warm scorpion extract 15.0 14. Propylene oxide (9) diglycerin 1.0 15. Diglycerol 5.0 16. 咕 ton gel 1% aqueous solution 30.0 17. Ethyl glutamic acid 0.3 18. Spherical nylon powder 1.0 19. Preservative amount: 20. Pure water residue 1282740 (Manufacturing method) A: Components 1 to 8 were mixed and dissolved at 85 °C. B: Ingredient 9 was heated to 85 ° C and A was added with sufficient stirring. C: Component B was cooled and micronized by a high pressure homogenizer. D: Components 10 to 20 were mixed and dissolved at room temperature. E: C was added to D and mixed to obtain a cosmetic liquid. The cosmetic liquid of Example 15 has a sticky feeling of water-soluble L. sodium ascorbate and has a sufficient moisturizing feeling, and is a cosmetic liquid having good usability. EFFECT OF THE INVENTION As described in detail above, the liquid cosmetic of the present invention can exert a whitening action of a water-soluble L-ascorbic acid derivative, and the feeling of use is good even in the presence of a water-soluble L-ascorbic acid derivative.