TWI242431B - Pharmaceutical compositions for treating pulmonary diseases - Google Patents

Pharmaceutical compositions for treating pulmonary diseases Download PDF

Info

Publication number
TWI242431B
TWI242431B TW089123039A TW89123039A TWI242431B TW I242431 B TWI242431 B TW I242431B TW 089123039 A TW089123039 A TW 089123039A TW 89123039 A TW89123039 A TW 89123039A TW I242431 B TWI242431 B TW I242431B
Authority
TW
Taiwan
Prior art keywords
dose
clinical
fev
asthma
cilomalast
Prior art date
Application number
TW089123039A
Other languages
English (en)
Chinese (zh)
Inventor
Peter N Goodfellow
Richard Nieman
Theodore J Torphy
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Application granted granted Critical
Publication of TWI242431B publication Critical patent/TWI242431B/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
TW089123039A 1999-11-02 2000-11-22 Pharmaceutical compositions for treating pulmonary diseases TWI242431B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US16315899P 1999-11-02 1999-11-02

Publications (1)

Publication Number Publication Date
TWI242431B true TWI242431B (en) 2005-11-01

Family

ID=22588737

Family Applications (1)

Application Number Title Priority Date Filing Date
TW089123039A TWI242431B (en) 1999-11-02 2000-11-22 Pharmaceutical compositions for treating pulmonary diseases

Country Status (29)

Country Link
EP (1) EP1225866A4 (no)
JP (1) JP2003513028A (no)
KR (1) KR20020057988A (no)
CN (1) CN1387404A (no)
AP (1) AP2002002496A0 (no)
AR (1) AR029189A1 (no)
AU (1) AU1357501A (no)
BG (1) BG106748A (no)
BR (1) BR0015270A (no)
CA (1) CA2388333A1 (no)
CO (1) CO5261512A1 (no)
CZ (1) CZ20021512A3 (no)
DZ (1) DZ3225A1 (no)
EA (1) EA200200518A1 (no)
EC (1) ECSP003747A (no)
HK (1) HK1049107A1 (no)
HU (1) HUP0203152A3 (no)
IL (1) IL149367A0 (no)
MA (1) MA26841A1 (no)
MX (1) MXPA02004350A (no)
NO (1) NO20022057L (no)
OA (1) OA12076A (no)
PE (1) PE20011005A1 (no)
PL (1) PL355261A1 (no)
SK (1) SK7592002A3 (no)
TR (1) TR200201211T2 (no)
TW (1) TWI242431B (no)
WO (1) WO2001032127A2 (no)
ZA (1) ZA200203435B (no)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2459757C (en) * 2001-09-19 2011-08-30 Altana Pharma Ag Combination
MXPA04003668A (es) * 2001-10-31 2004-07-22 Merck Patent Gmbh Inhibidores de fosfodiesteresa de tipo 4 y usos de los mismos.
UA82323C2 (uk) * 2002-08-09 2008-04-10 Меда Фарма Гмбх & Ко. Кг Нова комбінація глюкокортикоїду та pde-інгібітору для лікування респіраторних захворювань, алергічних захворювань, астми та хронічних обструктивних легеневих захворювань
TW200410923A (en) * 2002-10-17 2004-07-01 Ono Pharmaceutical Co Therapeutic agent for chronic obstructive pulmonary disease
WO2004087149A1 (ja) * 2003-03-31 2004-10-14 Kyowa Hakko Kogyo Co. Ltd. 医薬組成物
US20050026883A1 (en) * 2003-07-31 2005-02-03 Robinson Cynthia B. Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with a PDE-4 inhibitor for treatment of asthma or chronic obstructive pulmonary disease
CA2584169A1 (en) * 2004-10-13 2006-04-20 Kyowa Hakko Kogyo Co., Ltd. Remedies/preventives for chronic skin disease
WO2007045980A1 (en) * 2005-10-19 2007-04-26 Ranbaxy Laboratories Limited Compositions of phosphodiesterase type iv inhibitors
US8991390B2 (en) 2010-01-05 2015-03-31 Microdose Therapeutx, Inc. Inhalation device and method
WO2015063669A1 (en) 2013-10-30 2015-05-07 Wockhardt Limited Pharmaceutical compositions comprising combination of roflumilast and acebrophylline or pharmaceutically acceptable salts thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU7174794A (en) * 1993-06-18 1995-01-17 Smithkline Beecham Corporation Compounds
DE4332041C2 (de) * 1993-09-21 1997-12-11 Rentschler Arzneimittel Verwendung von Pentoxifyllin bei bestimmten Lungenerkrankungen
PE44995A1 (es) * 1994-01-27 1995-12-18 Schering Corp Furoato de mometasona para el tratamiento de las enfermedades pulmonares y de las vias respiratorias
SE9801368D0 (sv) * 1998-04-20 1998-04-20 Astra Ab New use

Also Published As

Publication number Publication date
EP1225866A4 (en) 2004-04-21
CN1387404A (zh) 2002-12-25
AR029189A1 (es) 2003-06-18
WO2001032127A3 (en) 2001-12-06
PL355261A1 (en) 2004-04-05
OA12076A (en) 2006-05-04
JP2003513028A (ja) 2003-04-08
IL149367A0 (en) 2002-11-10
HK1049107A1 (zh) 2003-05-02
PE20011005A1 (es) 2001-09-28
NO20022057D0 (no) 2002-04-30
ECSP003747A (es) 2002-05-23
CO5261512A1 (es) 2003-03-31
AU1357501A (en) 2001-05-14
CZ20021512A3 (cs) 2003-04-16
SK7592002A3 (en) 2002-11-06
CA2388333A1 (en) 2001-05-10
KR20020057988A (ko) 2002-07-12
WO2001032127A2 (en) 2001-05-10
NO20022057L (no) 2002-06-27
EA200200518A1 (ru) 2002-10-31
MXPA02004350A (es) 2002-11-07
HUP0203152A3 (en) 2004-06-28
BG106748A (en) 2003-02-28
MA26841A1 (fr) 2004-12-20
HUP0203152A2 (hu) 2003-01-28
TR200201211T2 (tr) 2002-08-21
DZ3225A1 (fr) 2001-05-10
BR0015270A (pt) 2002-06-18
EP1225866A2 (en) 2002-07-31
ZA200203435B (en) 2003-06-25
AP2002002496A0 (en) 2002-06-30

Similar Documents

Publication Publication Date Title
Bateman et al. Efficacy and safety of roflumilast in the treatment of asthma
US20050070514A1 (en) Therapies for treating respiratory diseases
KIPS et al. Long-acting inhaled β2-agonist therapy in asthma
JP4097285B2 (ja) 種々の頑固な疾患の治療のための医薬の製造に有用な組成物
EP3189836B1 (en) Desferrioxamine-metal complexes for the treatment of immune-related disorders
SA04250122B1 (ar) دواء جديد يحتوي على العامل المساعد بيتا 2 شديد الفعالية وطويل المفعول وذلك بالاتحاد مع مكونات فعاله أخرى
US20060069155A1 (en) Method for reducing exacerbations associated with COPD
TWI242431B (en) Pharmaceutical compositions for treating pulmonary diseases
Huerta et al. Forskolin compared with beclomethasone for prevention of asthma attacks: a single-blind clinical trial
US20040176419A1 (en) Composition comprising a pde-4 inhibitor and h1-receptor antagonist and the use thereof for the manufacture of a medicament for the treatment of respiratory diseases
Sabbah et al. Azelastine eye drops in the treatment of seasonal allergic conjunctivitis or rhinoconjunctivitis in young children
Meltzer Pharmacological treatment options for allergic rhinitis and asthma.
JP2005508963A (ja) 喘息を治療するためのサルメテロールとフルチカゾンプロピオネートを含む医薬の組み合せ
JP2004505039A (ja) Ｃｏｐｄに付随する増悪の減少方法
US20060035877A1 (en) Method and compositions for treating pulmonary diseases
JP2003522142A (ja) 炎症性疾患の治療法および治療用組成物
Gross et al. Fluticasone Propionate Versus Triamcinolone Acetonide
Lin et al. Treatment of allergic asthma
WO2001060358A1 (en) Method and compositions for treating fibrotic diseases
US20070053930A1 (en) Combination therapy for treatment of high cholesterol
AU2004205324A1 (en) Method and compositions for treating pulmonary diseases
US20030018071A1 (en) Method and compositions for treating fibrotic diseases
Beute et al. Evaluation of Real-Life Investigational Use of Enoximone in Asthma, the Third Step in Drug Repurposing: A Preliminary Report
JP4372723B2 (ja) 慢性疼痛の治療のための医薬の製造に有用な組成物
Dose Procaterol hydrochloride hydrate

Legal Events

Date Code Title Description
MM4A Annulment or lapse of patent due to non-payment of fees