TW506840B - Apparatus and method for regulating fluid pump pressures - Google Patents
Apparatus and method for regulating fluid pump pressures Download PDFInfo
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- TW506840B TW506840B TW090116418A TW90116418A TW506840B TW 506840 B TW506840 B TW 506840B TW 090116418 A TW090116418 A TW 090116418A TW 90116418 A TW90116418 A TW 90116418A TW 506840 B TW506840 B TW 506840B
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- pressure
- liquid volume
- fluid
- volume
- control device
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Classifications
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
- F04B43/00—Machines, pumps, or pumping installations having flexible working members
- F04B43/02—Machines, pumps, or pumping installations having flexible working members having plate-like flexible members, e.g. diaphragms
- F04B43/06—Pumps having fluid drive
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/15—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with a cassette forming partially or totally the flow circuit for the treating fluid, e.g. the dialysate fluid circuit or the treating gas circuit
- A61M1/155—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with a cassette forming partially or totally the flow circuit for the treating fluid, e.g. the dialysate fluid circuit or the treating gas circuit with treatment-fluid pumping means or components thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/15—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with a cassette forming partially or totally the flow circuit for the treating fluid, e.g. the dialysate fluid circuit or the treating gas circuit
- A61M1/156—Constructional details of the cassette, e.g. specific details on material or shape
- A61M1/1565—Details of valves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/15—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with a cassette forming partially or totally the flow circuit for the treating fluid, e.g. the dialysate fluid circuit or the treating gas circuit
- A61M1/159—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with a cassette forming partially or totally the flow circuit for the treating fluid, e.g. the dialysate fluid circuit or the treating gas circuit specially adapted for peritoneal dialysis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/28—Peritoneal dialysis ; Other peritoneal treatment, e.g. oxygenation
- A61M1/282—Operational modes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
- A61M5/16804—Flow controllers
- A61M5/16809—Flow controllers by repeated filling and emptying of an intermediate volume
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- G—PHYSICS
- G05—CONTROLLING; REGULATING
- G05D—SYSTEMS FOR CONTROLLING OR REGULATING NON-ELECTRIC VARIABLES
- G05D16/00—Control of fluid pressure
- G05D16/20—Control of fluid pressure characterised by the use of electric means
- G05D16/2006—Control of fluid pressure characterised by the use of electric means with direct action of electric energy on controlling means
- G05D16/2066—Control of fluid pressure characterised by the use of electric means with direct action of electric energy on controlling means using controlling means acting on the pressure source
- G05D16/2073—Control of fluid pressure characterised by the use of electric means with direct action of electric energy on controlling means using controlling means acting on the pressure source with a plurality of pressure sources
-
- G—PHYSICS
- G05—CONTROLLING; REGULATING
- G05D—SYSTEMS FOR CONTROLLING OR REGULATING NON-ELECTRIC VARIABLES
- G05D7/00—Control of flow
- G05D7/06—Control of flow characterised by the use of electric means
- G05D7/0617—Control of flow characterised by the use of electric means specially adapted for fluid materials
- G05D7/0629—Control of flow characterised by the use of electric means specially adapted for fluid materials characterised by the type of regulator means
- G05D7/0635—Control of flow characterised by the use of electric means specially adapted for fluid materials characterised by the type of regulator means by action on throttling means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/15—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with a cassette forming partially or totally the flow circuit for the treating fluid, e.g. the dialysate fluid circuit or the treating gas circuit
- A61M1/152—Details related to the interface between cassette and machine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/33—Controlling, regulating or measuring
- A61M2205/3331—Pressure; Flow
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T137/00—Fluid handling
- Y10T137/0318—Processes
Landscapes
- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Emergency Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- Vascular Medicine (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Automation & Control Theory (AREA)
- Mechanical Engineering (AREA)
- General Engineering & Computer Science (AREA)
- Fluid Mechanics (AREA)
- External Artificial Organs (AREA)
- Reciprocating Pumps (AREA)
- Control Of Positive-Displacement Pumps (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Description
506840 A7 五、發明說明(1) 技術領域 本發明有關流體流動控制裝置,具體言之,本發明 有關調節泵壓力。特別是,本發明提供一種用於增加一流 體流動控制裝置中的流體流率並維持所需要的壓力程度之 5方法及裝置。本發明亦有關可決定一泵對於與泵導通之一 管線的一末端之相對海拔高度之系統。 背景技藝 流體流動控制裝置之一項功能在於調節將流體運送 分配通過一管線之速率,流體控制裝置的部份範例為腹腔 10透析機以及靜脈注射流體輸送系統。流體流動控制系統可 包括一永久性设體,此永久性殼體不會直接接觸運送流體 且其中放置有一暴露於流體的可棄式匣。撓性臈或可回應 麼力的其他結構可將永久性與可棄式組件之間保持分離。 此控制系統及其子組件(特別是閥)的範例係揭露於美國專 15 利 4, 778, 451、4, 976, 162、5, 178, 182 號中,這些專利案 均頒予凱門(Kamen)且均以引用方式併入本文中。 一項針對流體流動控制裝置之問題譬如係出現在透 析處理中,患者希望盡量減少聯結至腹腔透析機所耗費的 時間,為了滿足患者的需求,可藉由增大泵送壓力來成比 20例地增加泵送入患者的導管内之流體的流率。然而,國際 規範(言如EN50072)係規定了患者導管中所容許的最大與 最小壓力,所容許的最大正壓力設為15〇公厘汞杈(〜3磅 每平方吋(psi)),而最小(或最大負壓力或吸取壓力)壓力 設為-75公厘汞柱(〜—u磅每平方吋)。習知技藝的透析 (請先閱讀背面之注意事項再填寫本頁)
-n ϋ I I I n n^OJ* I I 經濟部智慧財產局員工消費合作社印製 本紙張尺度適用中國國家標準(CNS)A4規格(210 297公釐) 90. 11· 2,°°° 506840 A7 ____ B7 五、發明說明(2) (請先閱讀背面之注意事項再填寫本頁) 機在將流體泵送人患者體内時係使用大約75公厘采柱 U.5碎每平方对)的泵送壓力。如果透析機與患者位於相 同的海拔高度,則施加至泵的墨力將會非常接近患者導管 上之壓力,且患者導管上的壓力將會比施加至泵的壓力更 5高。因此,為了確保安全係數,將聚送壓力設為比最大容 許壓力更低’以補償患者相對於透析機之位置的任何不確 定性。 發明概要 提供一種調節流體泵壓力之方法,其中係藉由在與 10末端的閥式導通中提供至少一個液體容積而依據一流體流 動控制裝置與/流體管線的一末端之間的相對高度來調節 流體泵壓力。將液體容積的壓力測量值予以校準,並開啟 閥以在液體容積與流體管線末端之間建立導通。量測與液 體容積相關聯之一壓力,並依據所量測到的壓力來調整流 15 體泵壓力。 經濟部智慧財產局員工消費合作社印製 較佳,流體流動控制裝置具有兩個液體容積,一第 一液體容積係與一第二液體容積呈現閥式導通,流體管線 較佳與兩液體容積均呈閥式導通。將液體容積中之壓力予 以校準,並建立一液體容積與流體管線末端之間的導通。 20 量測一液體容積相關聯之一壓力,並依據所量測到的壓力 來調整流體泵壓力。 流體流動控制裝置較佳係包括··對於各液體容積之一 控制容積;對於各控制容積之/換能器,·及用於讀取與儲 存>1力值、計算與找出壓力值之間的相關聯性並依據所找 -4- 本紙張尺度適用中國國豕標準(CNS)A4規格(210 X 297公釐) 90. 11. 2,000 506840 A7 B7 經濟部智慧財產局員工消費合作社印製 五、發明說明(3) 出的相關聯性來計算出壓力值之-處理器。處理器可依據 壓力值及/或所調節的流體泵壓力來估算海拔高度差。苄 體流動控制裝置亦可包括壓力構件,藉以將二;二 以加壓。此裝置可進-步包括用於控制液體容積血管線末 5端之間的流體導通之多種閥配置的其中一種閱配置。處理 器亦可控制閥配置、用於將液體容積予以加壓之構件、 及流體泵壓力。 另一項實施例中,液體容積及控制容積本身係為— i的-部份。泵較佳包括-撓性膜,撓性膜係分隔液體容 1〇積與控制容積。其他實施例中,流體流動控制裝置包括一 系。 -種用於偵測-第-位置與-第二位置之間的相街 海拔高度之方法中,在第一位置上提供一流體流動控制裝 置’其中具有至少一個膜泵與第二位置呈閥式導通。膜泵 係與第二位置相隔離,並將膜泵的一壓力換能器予以^ 準。隨後將閥動開啟以建立膜泵與第二位置之間的導通^ 量測膜泵的壓力,並估算位於第一位置與第二位置之間 相對海拔高度。 另一項實施例中,壓力換能器的校準可能包括:藉由 與第一位置的壓力呈現平衡之流體來充注膜泵,量測二第 膜泵的一校準壓力,藉由與一已知(亦即預定或所量測到 的)校準壓力呈現平衡之流體來充注膜泵,以及量測膜泵 的一第二校準壓力。可依據已知的校準壓力、第一校準壓 力及第二校準壓力來估算第一位置與第二位置之間的相對 15 20 本纸張尺度適用中國國家標準(CNS)A4規^〇 x 297公爱 以 90· 11· 2,0〇〇 (請先閱讀背面之注意事項再填寫本頁)
506840 A7 五、發明說明( 10 15 經濟部智慧財產局員工消費合作社印製 20 海拔高度。 圖式簡覃說明 參照下列描述及圖式可更清楚瞭解本發明,其中: 圖1為一種習知技藝的流體流動控制裝置之立體圖; 圖2顯示圖1的裝置中所包含之一種膜基礎式流體 流動控制系統; 圖3(a)及3(b)示意顯示一流體管線的末端處所經歷 的壓力與流體流動控制裝置的相對海拔高度之間的關係; 圖4顯示根據本發明的一項實施例用於偵測相對海 拔高度並調節流體栗壓力之方塊圖; a 圖5(a)及5(b)為顯示根據未發明另一項實施例之校 準與調節方法之方塊圖; 圖6為圖5的方法所產生之關係的圖示。 特定實施例之詳細jgi 圖1顯示一種習知技藝的流體流動控制裝置2〇〇,一 可棄式匣201係穩固地安裝在流體流動控制裝置2〇〇上。 從一加熱的溶液袋202經由一溶液入口管線203維持與匣 201的流體導通,且亦保持導通至一出口 204的一末端 208。流體流動控制裝置2〇〇具有一阻斷板205,阻斷板 205在受到流體流動控制裝置2〇〇予以啟動時將會阻斷入 口管線203與出u管線204。圖中之流體流動控制裝置 200具有兩個泵300與31〇,各泵具有入口與出口閥 306、307、316 及 317。 (請先閱讀背面之注意事項再填寫本頁)
J3V _6_ 本紙張尺度適用中國國家標準(CNS)A4 <^(210 X 297公楚) 90· 11. 2,000 經濟部智慧財產局員工消費合作社印製 506840 A7 B7 五、發明說明(5) 圖2顯示圖1的流體流動控制裝置200中所使用並 具有一第一泵300及一第二泵310之一膜基礎式流體控制 流動裝置。撓性膜303在圖中將第一泵300分成一第一控 制容積301及一第一液體容積302,可經由一第一壓力管 5 線304將第一控制容積301予以加壓,藉由附接至第一控 制容積301並與其呈現流體導通之一第一壓力換能器305 來量測第一控制容積301中的壓力。同樣地,撓性膜313 將第二泵310分成一第二控制容積311及一第二液體容積 312,可經由一第二壓力管線314將第二控制容積311予 10 以加壓,藉由附接至第二控制容積311並與其呈現流體導 通之一第二壓力換能器315來量測第二控制容積311中的 壓力。可利用一種控制氣體或液體或藉由譬如泵、活塞、 加壓貯槽、閥及通口等此技藝習知的其他方法來產生加壓 作用。如上述,這些加壓裝置更詳細描述於以引用方式併 15 入本文中之頒予凱門的美國專利案。 一第一出口閥306係控制從第一液體容積302至出 口管線204之出口流,而一第二出口閥316則控制從第二 液體容積312至出口管線204之出口流。因此,來自第一 泵300及第二泵310之出口流彼此之間以及與出口管線 20 304的末端208(見圖1)之間係呈現流體導通。一第一入 口閥307係控制進入第一液體容積302之入口流,而一第 二入口閥317則控制進入第二液體容積312之入口流。來 自第一泵300及第二泵310之入口流在彼此之間以及經由 溶液入口管線203與加熱的溶液袋302之間係呈現流體導 本紙張尺度適用中國國家標準(CNS)A4規格(210 X 297公釐) 90. 11. 2,000 (請先閱讀背面之注意事項再填寫本頁) 訂.-------- 506840 經濟部智慧財產局員工消費合作社印製 A7 B7 ______ 五、發明說明(Ο 通。當受到啟動時,阻斷板205將出口管線204及溶液袋 202與泵300及310隔離開來,同時在任一組或兩組閥打 開時可讓兩泵300及310之間呈現流體導通。 圖3(a)示意顯示在與一流體流動控制裝置200相同 5海拔高度處與一主體31相導通之一流體管線204。當管 線204的末端208以及流體流動控制裝置200處於相同海 拔高度時,管線204末端208上的壓力係等於流體流動控 制裝置200中的壓力。圖3(b)示意顯示位於比流體流動 控制裝置200更低海拔高度處之一主體31,當發生此情 10 形時,管線204末端208中的壓力係大於流體流動控制裝 置200中的壓力。譬如,若流體流動控制裝置200為一種 腹腔透析機時,可計算出相對海拔高度與壓力差之間的關 係。在患者與透析機之間的0· 3公尺(一呎)海拔高度差將 造成透析機中的壓力與附接至患者的導管中的壓力之間具 15有大約25公厘汞柱(0· 5碌每平方忖)差。顯然,患者相 對於透析機處於愈低位置,則導管中的壓力將愈大。因 此’對於上述範例,如果能夠決定患者與透析機之相對海 拔高度’則泵送壓力將減小以保持安全係數。相反地.,上 述範例中,可以一較低壓力(較高的負壓力)從患者安全地 20 抽出流體而仍然保持相同的安全係數。 圖4為顯示根據本發明之一項實施例用於偵測相對 海拔高度及調節流體泵壓力之方法的方塊圖,此項實施例 中’採用圖2的流體流動控制系統。至少一個泵300及 310的壓力係與流體管線204末端208處的壓力具有相關 本紙張尺度適用中國國家標準(CNS)A4規格(210 x 297公釐) 90. 11. 2,000 I--I--— 丨 I —丨—丨 ί —丨訂— 1 — — - (請先閱讀背面之注意事項再填寫本頁)9
五、發明說明(7) 經濟部智慧財產局員工消費合作社印製 也1生,流體管線204末端208處的壓力則可能與海拔高度 差有關,因為在膜基礎式系統中,撓性膜3〇3及313係以 彈性能量方式來儲存部份的pV功而使得處於平衡的膜之 間具有略為不同的壓力,所以相關聯性彳艮複雜。因此,本 5發明係在量測相對海拔高度之前先行提供測量、相關聯性 以及關係的發展。若沒有此等相關聯性,相對海拔高度的 估异值可能具有高達8至1〇吋的誤差,本發明人已經發 現··此等系統中之新的膜表現出磁滯作用,此磁滯作用似 乎Ik著膜的反覆固定而遞減,因此,可在將膜予以撓屈的 10其他啟動程序完成之後進行校準。 參照圖2之各種標示物件,在程序4〇1中校準至少 一個泵300或310中之壓力。程序402中,在至少一個泵 300或310與管線204之間建立流體導通。在程序4〇3中 量測與管線相導通之泵中的靜壓力,並在程序4〇4中估算 15管線與流體流動控制裝置之間的相對海拔高度,可利用= 中所量測的靜壓力並利用-高度差與壓力差之間的一已知 關係(譬如每25公厘汞柱〇·3公尺(卜尺))來達成此作° 用。最後,可調整泵壓力以容納程序4〇5中的高度差。 圖5(a)係為突顯出根據本發明的一項實施例採用圖 20 2的流體流動控制系統之啟動及校準之方塊圖,因為任二 容積或兩容積可在先前程序中呈部份充滿狀,在程序 中將液體容積302及312排空,排空兩液體容積3〇2及 312之後,程序502中將出口閥3〇6及316均予以關閉。 在程序503中以流體藉由重力充注兩個液體容積3〇2及 (請先閱讀背面之注意事項再填寫本頁)
A7 _ B7
(請先閱讀背面之注意事項再填寫本頁) 506840 312。此項實施例中,如圖1所示從加熱的溶液袋2〇2經 由一入口管線獲取流體。因為溶液袋2〇2座落在流體流動 控制裝置200的頂部上,在溶液袋202與泵3〇〇及31〇之 間海拔咼度差造成之靜壓頭係為已知且很小。藉由重力充 5注作為溶液袋2〇2之液體容積302及312係位於比液體容 積302及312更高的海拔高度。 在程序504中利用壓力換能器305及315來量測控 制容積301及311中之壓力。換能器可為用於將一壓力轉 換成成5虎(較佳為電说说)之任何儀器。程序中所量 10測的壓力係與一零靜壓頭相關聯(或定義為零之靜壓頭)。 程序505中將兩個泵入口閥307及317均予關閉,並起動 阻斷板2 0 5,關閉以及啟動的順序並不重要。程序5 q 5的 作用在於隔離阻斷板205上游的出口管線2〇4以及液體容 積302及312中之流體。程序506中,兩出口閥3〇6及 15 316均打開,由於兩出口閥306及gig均打開而使得流體 忐夠泵送於兩液體容積302及312之間,同時使得位於液 體容積302及312内部之全體流體容積保持固定。 程序507中,將第一控制容積3〇1加壓至一預先選 定的正壓力,預先選定的正壓力之選擇取決於譬如相對海 20拔咼度的預期範圍以及壓力換能器305及315的動態範圍 等因素。第一控制容積301中的壓力係模擬一種已知的靜 壓頭。程序508中,藉由壓力換能器315來量測第二控制 容積311中的壓力。 假設兩膜具有相同的壓力傳輸效果,則可從兩組壓 -10- 本紙張尺度適用中國國家標準(CNS)A4規格(210 X 297公釐) 506840 A7 B7 經 濟 部 智 慧 財 產 局 員 工 消 費 合 作 社 印 製 五、發明說明(9) 力測量值獲得-種關係,可在此點計算校準常數。然而, 在本發明的其他實施例中,重覆進行程序5〇7及5〇8。此 時,在程序509中使用_預先選定的負壓力將第一控制容 積301加壓,並在程序51〇中量測第二控制容積中的壓 5力。在此項實施例的程序511中,從三組壓力測量值獲得 一種關係,並計算校準常數。 圖5(b)顯不在圖的啟動與校準程序之後的程序 之方塊圖,程序512中,再度以重力充注液體容積302及 312,在程序513中調整閥出口而能夠僅在第二泵31〇與 1〇出口管線204之間呈現流體導通,藉由排空第一控制容積 3〇1二關閉第一出口閥寫及對於阻斷板2〇5解除啟動來 達成,整,這些作用的結果可使得第二泵310與出口管線 2G4呈現流體導通同時將第二泵31G與系統的其餘部份隔 離開來&序514中,壓力換能器315係量測第二控制容 積311巾的壓力,並在程序515巾,依據第二控制容積中 的[力以及校準期間產生的校準常數來估算相對的海拔高 度。 ^ 採用相對海拔南度(縱座標袖)以及程序514中 、J的壓力p(控制容積橫座標軸)作為座標系之兩線性擬 66 [si — 靜豆二不,可藉由方程式冰從相對海拔高度來決定 产,齪力其中為p壓力,p為流體密度,g為重力加速 i直t:相對海拔高度。藉由橫座標軸上的p(控制容積)值在 (位於/與六個校準壓力值得出的線性擬合之交點來決定 <縱座標軸上的)一點Η。P遺後,在程序516巾可藉由 15 20
X 297公釐) 90. 11. 2,〇〇〇 (請先閲讀背面之注意事項再填寫本頁)
506840 A7 緩濟部智慧財產局員工消費合作社印製 五、發明說明(磅 海拔高度差來計算流體管線204的末端208上之壓力p 端)以容納高度差。 可採用一種電腦程式產品來實行本發明之方法,電 腦程式產品包含一電腦可使用的媒體,此媒體具有電腦可 5讀取的程式碼。電腦可讀取的程式係可能包含··用於讀取 與儲存液體容積302或312内的壓力值之程式螞;用於叶 算與找出所儲存壓力值之間的相關聯性之程式碼;用於依 據所找出的相關聯性來計算出壓力值之程式碼;以及用於 依據所計算出的壓力來估算海拔高度差之程式碼。電腦程 式產品亦可包括··用於依據海拔高度差來計算—所需要的 流體泵壓力之程式碼;以及用於根據所需要的系壓力來調 整系麼力之程式碼。 電腦程式產品可在作為㈣器之―資料處理單元上 運作,此單元可能能夠藉由調整泵壓力來調整果送至末端 208之流體的流率,譬如,如果計算決定出流體管線2〇4 的末端208以及流體控制系統處於相同高度則㈣力可 月匕女王也s加至间於75公厘汞柱而造成較快的流體流 率。並且’可在處理器控制下進行所有的方法程序,可提 供-記憶體依據末端208與系統之間的海拔高度差來 官線204末端208上之安全壓力的上限。能夠接收關於海 拔高度差的資料之-處理器隨後將可計算並控制壓力的程 度。 f然’在上述线巾’用料定相對海拔高度之液 體容積為包含膜的菜’可瞭解可提供分離的泵、控制容 (末 10 15 20 _ ^紙張尺度適用中國標規格(21〇><297公f 90* 21· 2,〇〇〇 -II —I! — — — - IIIIII — ^» — — — 111 — (請先M讀背面之注意事項再填寫本頁) 經濟部智慧財產局員工消費合作社印製 506840 A7 __B7_ 五、發明說明( 積、及液體容積,並且液體容積及控制容積可沿著前往流 體管線末端之流體路徑位於與泵不同的地點,此項實施例 中,液體容積與泵或控制容積之間的高度差應為固定,故 具有已知的高度差。亦應瞭解液體容積及加壓構件不需處 5 於相同位置,且第一及第二液體容積可同樣位於分離的位 置。 熟悉此技藝者進一步瞭解可作其他修改而不脫離申 請專利範圍所界定之本發明的精神與範圍。 本紙張尺度適用中國國家標準(CNS)A4規格(210 X 297公釐) 90. 11. 2,000 (請先閱讀背面之注意事項再填寫本頁)
506840 A7 B7 經濟部智慧財產局員工消費合作社印製 五、發明說明(4 圖式之代號說明 代表符號:名稱 31:主體 200:流體流動控制裝置 5 201:可棄式匣 202:加熱的溶液袋 203:溶液入口管線 204:出口管線 205:阻斷板 10 208:末端 300:第一泵 301:第一控制容積 302:第一液體容積 303:撓性膜 15 304:第一壓力管線 305:第一壓力換能器 306:第一出口閥 307:第一入口閥 310:第二泵 20 311:第二控制容積 312:第二液體容積 313:撓性膜 314:第二壓力管線 315:第二壓力換能器 -14- -------I-------------------- (請先閱讀背面之注意事項再填寫本頁) 本紙張尺度適用中國國家標準(CNS)A4規格(210 X 297公釐) 90. 11. 2,000 506840 A7 B7 五、發明說明( 316:第二出口閥 317:第二入口閥 經濟部智慧財產局員工消費合作社印製 -15- 本紙張尺度適用中國國家標準(CNS)A4規格(210 X 297 ;釐) (請先閱讀背面之注意事項再填寫本頁)
90. 11. 2,000
Claims (1)
- 506840 A8 B8 C8 D8 六、申請專利範圍 1 · 一種用於調節流體泵壓力之方法,該方法包含: (請先閱讀背面之注意事項再填寫本頁) 提供一流體流動控制裝置,該流體流動控制裝置具有 與一流體管線的一末端呈現閥式導通之至少一個液體 容積; 校準該液體容積中之壓力; 建立該液體容積與該末端之間的導通; 量測與該液體容積相關之一壓力;及 依據所量測之壓力來調整該流體泵壓力。 2·如申請專利範圍第1項之方法,其中該校準液體容積 係包含: 將該液體容積與該末端隔離開來; 量測與該液體容積呈現壓力導通之一控制容積的一第 一校準壓力; 將該液體容積加壓;及 量測該控制容積之一第二校準壓力。 3.如申請專利範圍第1項之方法,其中該校準液體容積 係包含: 將該液體容積與該末端隔離開來; 經濟部智慧財產局員工消費合作社印製 量測與該液體容積呈現壓力導通之一控制容積的壓 力; 對於該液體容積施力口正壓力; 在該液體容積受到正壓力時量測該控制容積的壓力; 對於該液體容積施加負壓力;及 在該液體容積受到負壓力時量測該控制容積的壓力。 16 90. 11. 2,000 本紙張尺度適用中國國家標準(CNS)A4規格(210 X 297公釐)六、申請專利範 圍 4.=申請專利範圍第丨項之方法,其中該液體容積包括 :撓性膜’該撓性膜將該液體容積與其中進行壓力測 量之一控制容積分離開來。 5· ^申請專利範圍第W之方法,其中該流體流動控制 裝置包括一泵。 6. 二種用於調節流體泵壓力之方法,該方法包含: 提流體流動控制裝置,該流體流動控制裝置 -第-液體容積及-第二液體容積,該第_液體ς 與該第二液體容積呈現閥式導通; 積 提供一流體管線,該流體管線具有盥該 ^ ^ ^ 、茨弟—液體容積 及该弟二液體容積呈現閥式導通之一末端; 、 校準該液體容積中之壓力; ’ 建立該液體容積與該末端之間的導通; 1測與該第一液體容積相關之一壓力; 依據所量測之壓力來調整該流體泵壓力。 7. =t專利範圍第6項之方法,其中該校準液體容積 將該液體容積與該末端隔離開來; 'Sr *:8ιί ^ ^ 一、、六碰办彳士 …… 關之第 量測與該該第二液體容積相關之第二校準壓力;及 依據所量測之壓力來調整該流體泵壓力。 如申請專利範圍第6項之方法,其巾職準液體容積 17 泰紙張尺度適用中國國家標準(CNS)A4規格公釐 90·江 2,000 -----------· I------訂—I-----1 (請先閱讀背面之注意事項再填寫本頁) 經濟部智慧財產局員工消費合作社印製 S測與該第一液體容積及該第二液體容積相 校準壓力; ' 將該第一液體容積加壓; 川 054U 六、申請專利範圍 係包含: 將該液體容積與該末端隔離開來; 量測與該第-液體容積及該第二液體容積 校準壓力; 弟一 對於該第一液體容積施加正壓力; 在該第-液體容積受到正勤時量測與該第 積相關之一第二校準壓力; 篮合 對於該第一液體容積施加負壓力; 在該第-液體容積受到負壓力時量測與該第二液 積相關之一第三校準壓力; " 依據所量測之壓力來調整該流體泵壓力。 訂 9. 如申請專利範圍第6項之方法,其中該等第_ «容2各包括__撓性膜’該触财贿體容積與 制容積分離開,且其中從該控制容積取得壓力測 10. 如申請專利範圍第6項之方法,其中該等第一及第二 液體容積係配置於一匿内。 圍第1〇項之方法’其中該賴動控制 12·^=於估异_第—位置與_第二位置之間的相對海 拔咼度之方法,該方法包含· 將-流體流動控制裝置放置在該第_ 流動控制裝置具有與該第二位置呈現間式導通之一膜 泵,該膜泵具有一屋力換能器; I______ 18 90* 2,〇〇〇 本紙張尺度適财_家標準((:Νϋ格(2】g χ 297公^ 506840 A8 B8 C8 D8 六、申請專利範圍 將該膜泵與該第二位置隔離開來; 校準該壓力換能器; (請先閱讀背面之注意事項再填寫本頁) 建立該膜泵與該第二位置之間的導通; 藉由該壓力換能器量測該膜泵中之壓力;及 依據該壓力估算相對海拔高度。 13. 如申請專利範圍第12項之方法,其中該校準壓力換能 器包含: 藉由與該第一位置的壓力呈現壓力平衡之流體來充注 該膜栗; 量測該膜泵中之一第一校準壓力; 藉由與一已知校準壓力呈現壓力平衡之流體來充注該 膜泵; 量測該膜泵中之一第二校準壓力;及 藉由依據該已知校準壓力、該第一校準壓力及該第二 校準壓力在壓力與相對海拔高度建立一線性擬合來估 算該相對海拔高度。 14. 如申請專利範圍第13項之方法,其中藉由一處理器來 決定該相對海拔高度。 經濟部智慧財產局員工消費合作社印製 15·—種電腦程式產品,其用於一處理器上以決定一第一 位置與一第二位置之間的一海拔高度差,其中一流體 流動控制裝置係位於該第一位置上,該流體流動控制 裝置包括經由一流體管線的一末端與一第二位置呈現 閥式導通之至少一個液體容積,該電腦程式產品包含 一電腦可使用的媒體,該媒體上具有電腦可讀取的程 19 90. 11. 2,000 本紙張尺度適用中國國家標準(CNS)A4規格(210 X 297公釐) 506840 六、申請專利範圍 式碼,該電腦可讀取的裎式碼係包含: 用於讀取及儲存該等泵内的壓力值之程式碼· =於計算及找出所儲麵力值之間的相_性之程式 用於依據所找出的相關聯性來計算出壓力值之矛。弋 碼,及 用於依據所計算出的壓力來估算該海拔高度差之程式 碼0 16.如申請專利範圍第15項之電腦程式產品,其進一步包 之 用於依據該海拔高度差來計算一所需要的栗送壓力 程式碼;及 用於依據該所需要的泵壓力來調整該流體流動控制裳 置内的泵送壓力之攀式馬^、 17·-種電腦程式產品,其用於一處理器上以調節流體泵 壓力,其中一流體流動控制裝置係位於該第一位置 上’该流體流動控制裝置包括、經由一流體管線的一末 立而與-第一位置呈現閥式導通之至少一個液體容積, 該電腦程式產品包含-電腦可使用的媒體,該媒體上 具有電腦可讀取的程式碼,該電腦可讀取的程式碼係 包括: 用於讀取及儲存該等泵内的壓力值之程式碼; 用於計算及找出所儲存麼力值之間的相關聯性之程式 碼; 90. 11. 2,000 經濟部智慧財產局員工消費合作社印製 506840 A8 B8 C8 D8 六、申請專利範圍 用於依據所找出的相關聯性來計算出壓力值之程式 碼;及 用於依據所找出的相關聯性來計算出一所需要的泵送 壓力之程式碼。 18.—種流體流動控制裝置,其用於偵測一第一位置與一 第二位置之間之一海拔高度差,其中該裝置係位於該 第一位置上,該流體流動控制裝置包含: 至少一個液體容積; 一流體管線,其與該液體容積呈現閥式壓力導通,該 流體管線具有位於該第二位置之一末端; 至少一個換能器,其用於量測與該液體容積相關之壓 力;及 一處理器,其用於: —讀取及儲存壓力值; —計算及找出該等壓力值之間的一相關聯性; 一依據所找出之相關聯性來計算出壓力值;及 依據該等所計算出的壓力來估算該海拔高度差。 19·如申請專利範圍第18項之裝置,其中所計算及找出之 該相關聯性為一線性擬合(linear fit)。 20. 如申請專利範圍第18項之裝置,其中該液體容積包括 一撓性膜,該撓性膜將該液體容積與一控制容積予以 分離,其中從該控制容積取得該等壓力測量值。 21. 如申請專利範圍第18項之裝置,其中該液體容積配置 於一匣内。 21 本紙張尺度適用中國國家標準(CNS)A4規格(210 X 297公釐) 90. 11. 2,000 -------II------------訂·-------- (請先閱讀背面之注意事項再填寫本頁) 經濟部智慧財產局員工消費合作社印製 506840 A8 B8 C8 D8 六、申請專利範圍 22.如申請專利範圍第18項之裝置,其進一步包含至少一 個栗。 23·如申請專利範圍第18項之裝置,其進一步包含至少一 個活塞。 24. —種用於調節流體泵壓力之系統,該系統包含: 一流體流動控制裝置,其具有與一流體管線的一末端 呈現閥式導通之至少一個液體容積,該流體流動控制 裝置包括用於將該液體容積加壓之壓力構件; 一閥配置,其用於控制該至少一個液體容積與該末端 之間的流體導通; 一換能器,其用於量測與該至少一個液體容積相關之 一壓力;及 一控制器,其用於控制該閥配置、該用於加壓液體容 積之構件、及該流體泵壓力,且其中該控制器係依據 該換能器所量測的壓力來調整該流體泵壓力。 25. —種用於調節流體泵壓力之系統,該系統包含·. 一流體流動控制裝置,其具有與彼此之間並與一流體 管線的一末端之間呈現閥式導通之第一及第二液體容 積,該流體流動控制裝置包括用於將至少一個液體容 積加壓之壓力構件; 一閥配置,其用於控制該液體容積之間以及與該末端 之間的流體導通, 一換能器,其用於量測與至少一個液體容積相關之一 壓力;及 22 本紙張尺度適用中國國家標準(CNS)A4規格(210 X 297公釐) 90. 11. 2,000 ---------I--i I----—訂·-------- (請先閱讀背面之注意事項再填寫本頁) 申清專利範圍 積其用於控制該閥配置、該用於减液體容 兮換At „„及°亥/;IL體果壓力’且其中該控制器係依據 該換μ所量測的壓力來調整該流體I壓力。 26·如申請專利範圍第25 、之糸、、先其中該控制器可使得 销配置將該液體容積與該末端隔離開來; 該換能器係量測與該末端隔離時之該第一液體容積相 關之壓力; ' 該用於加壓該第二液體容積之構件;及 量測在已經加壓該第二液體容積中的壓力之後與該第 一液體容積相關之壓力。 ^ A如申請專利範圍第25項之系統,其中該賴容積包括 一撓性膜。 28.如申請專利範圍第27項之系統,其中該至少一個液體 容積配置於一匣内。 且 經 濟 部 智 慧 財 產 局 員 工 消 費 合 社 印 製 本紙張尺度適用中國國家標準(CNS)A4規格(210 X 297公釐)
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2000
- 2000-07-10 US US09/612,005 patent/US6503062B1/en not_active Expired - Lifetime
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2001
- 2001-06-25 JP JP2003516606A patent/JP4900887B2/ja not_active Expired - Fee Related
- 2001-06-25 BR BRPI0112320A patent/BRPI0112320B8/pt not_active IP Right Cessation
- 2001-06-25 AU AU2001298000A patent/AU2001298000A1/en not_active Abandoned
- 2001-06-25 EP EP10075266A patent/EP2289577A1/en not_active Withdrawn
- 2001-06-25 WO PCT/US2001/041131 patent/WO2003011376A2/en active Search and Examination
- 2001-06-25 EP EP01274336A patent/EP1357958B1/en not_active Revoked
- 2001-06-25 MX MXPA03000328A patent/MXPA03000328A/es active IP Right Grant
- 2001-06-25 DE DE60142797T patent/DE60142797D1/de not_active Expired - Lifetime
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- 2001-07-05 TW TW090116418A patent/TW506840B/zh not_active IP Right Cessation
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- 2002-12-16 US US10/320,178 patent/US6808369B2/en not_active Expired - Lifetime
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- 2008-07-22 US US12/177,625 patent/US7853362B2/en not_active Expired - Fee Related
- 2008-09-29 JP JP2008249889A patent/JP4900969B2/ja not_active Expired - Fee Related
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2010
- 2010-12-14 US US12/967,846 patent/US8731726B2/en not_active Expired - Fee Related
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TWI401067B (zh) * | 2005-09-28 | 2013-07-11 | Alcon Inc | 用於眼內壓控制之手術匣 |
CN106730090A (zh) * | 2016-12-13 | 2017-05-31 | 中国船舶重工集团公司第七六研究所 | 自动腹膜透析机用压力传感器状态检测装置及方法 |
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JP2004536994A (ja) | 2004-12-09 |
BR0112320A (pt) | 2006-05-09 |
US20030086794A1 (en) | 2003-05-08 |
US20050118038A1 (en) | 2005-06-02 |
DE60142797D1 (de) | 2010-09-23 |
EP1357958A2 (en) | 2003-11-05 |
US20080031746A9 (en) | 2008-02-07 |
MXPA03000328A (es) | 2003-06-09 |
WO2003011376A2 (en) | 2003-02-13 |
AU2001298000A1 (en) | 2003-02-17 |
CA2418669A1 (en) | 2003-02-13 |
CA2418669C (en) | 2011-10-18 |
US7853362B2 (en) | 2010-12-14 |
US6808369B2 (en) | 2004-10-26 |
US8989906B2 (en) | 2015-03-24 |
BRPI0112320B8 (pt) | 2021-06-22 |
EP2289577A1 (en) | 2011-03-02 |
WO2003011376A8 (en) | 2003-09-12 |
US7421316B2 (en) | 2008-09-02 |
US20140249683A1 (en) | 2014-09-04 |
JP4900969B2 (ja) | 2012-03-21 |
US8731726B2 (en) | 2014-05-20 |
EP1357958B1 (en) | 2010-08-11 |
US20110085923A1 (en) | 2011-04-14 |
JP4900887B2 (ja) | 2012-03-21 |
JP2009068495A (ja) | 2009-04-02 |
US20080273996A1 (en) | 2008-11-06 |
US6503062B1 (en) | 2003-01-07 |
BR0112320B1 (pt) | 2011-08-09 |
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