TW358109B - Stabilized ophthalmically compatible compositions and method of stabilizing polymer compositions the invention relates to stabilized ophthalmically compatible compositions and method of stabilizing polymer compositions - Google Patents
Stabilized ophthalmically compatible compositions and method of stabilizing polymer compositions the invention relates to stabilized ophthalmically compatible compositions and method of stabilizing polymer compositionsInfo
- Publication number
- TW358109B TW358109B TW084113926A TW84113926A TW358109B TW 358109 B TW358109 B TW 358109B TW 084113926 A TW084113926 A TW 084113926A TW 84113926 A TW84113926 A TW 84113926A TW 358109 B TW358109 B TW 358109B
- Authority
- TW
- Taiwan
- Prior art keywords
- compositions
- stabilized
- ophthalmically compatible
- stabilizing polymer
- polymer compositions
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 6
- 229920000642 polymer Polymers 0.000 title abstract 4
- 230000000087 stabilizing effect Effects 0.000 title 2
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 abstract 2
- 229920002125 Sokalan® Polymers 0.000 abstract 2
- RPNUMPOLZDHAAY-UHFFFAOYSA-N Diethylenetriamine Chemical compound NCCNCCN RPNUMPOLZDHAAY-UHFFFAOYSA-N 0.000 abstract 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 abstract 1
- MKUXAQIIEYXACX-UHFFFAOYSA-N aciclovir Chemical compound N1C(N)=NC(=O)C2=C1N(COCCO)C=N2 MKUXAQIIEYXACX-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 239000011230 binding agent Substances 0.000 abstract 1
- 239000002738 chelating agent Substances 0.000 abstract 1
- 239000003292 glue Substances 0.000 abstract 1
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 abstract 1
- 125000000325 methylidene group Chemical group [H]C([H])=* 0.000 abstract 1
- 150000002903 organophosphorus compounds Chemical class 0.000 abstract 1
- 239000004584 polyacrylic acid Substances 0.000 abstract 1
- 229910052708 sodium Inorganic materials 0.000 abstract 1
- 239000011734 sodium Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
- C08K5/00—Use of organic ingredients
- C08K5/49—Phosphorus-containing compounds
- C08K5/51—Phosphorus bound to oxygen
- C08K5/53—Phosphorus bound to oxygen bound to oxygen and to carbon only
- C08K5/5317—Phosphonic compounds, e.g. R—P(:O)(OR')2
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Ophthalmology & Optometry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Polymers & Plastics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Preparation (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Materials For Medical Uses (AREA)
- Dental Preparations (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/493,761 US5683993A (en) | 1995-06-22 | 1995-06-22 | Compositions and methods for stabilizing polymers |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TW358109B true TW358109B (en) | 1999-05-11 |
Family
ID=23961593
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW084113926A TW358109B (en) | 1995-06-22 | 1995-12-27 | Stabilized ophthalmically compatible compositions and method of stabilizing polymer compositions the invention relates to stabilized ophthalmically compatible compositions and method of stabilizing polymer compositions |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US5683993A (enExample) |
| EP (1) | EP0833609B1 (enExample) |
| JP (3) | JP4260881B2 (enExample) |
| AT (1) | ATE208189T1 (enExample) |
| AU (1) | AU715686B2 (enExample) |
| CA (1) | CA2222646C (enExample) |
| CY (1) | CY2323B1 (enExample) |
| DE (1) | DE69616791T2 (enExample) |
| DK (1) | DK0833609T3 (enExample) |
| ES (1) | ES2167581T3 (enExample) |
| PT (1) | PT833609E (enExample) |
| TW (1) | TW358109B (enExample) |
| WO (1) | WO1997000669A1 (enExample) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2284202T3 (es) * | 1997-05-14 | 2007-11-01 | Senju Pharmaceutical Co., Ltd. | Preparaciones acuosas en suspension con excelente redispersabilidad. |
| DK0893121T3 (da) * | 1997-06-27 | 2002-06-17 | Akzo Nobel Nv | Flydende oral medicinopløsning |
| DE19744113A1 (de) * | 1997-10-06 | 1999-04-15 | Mann Gerhard Chem Pharm Fab | Dexamethason-Gel |
| EP0938896A1 (en) * | 1998-01-15 | 1999-09-01 | Novartis AG | Autoclavable pharmaceutical compositions containing a chelating agent |
| US5885550A (en) * | 1998-07-02 | 1999-03-23 | Vallier; Deandra K. | Ophthalmic whitening solution |
| US6627660B1 (en) * | 1999-11-16 | 2003-09-30 | New River Pharmaceuticals Inc. | Stabilized thyroxine compounds |
| WO2002070648A2 (en) | 2000-11-17 | 2002-09-12 | Hematech, Llc | Expression of xenogenous (human) immunoglobulins in cloned, transgenic ungulates |
| AU2002360939A1 (en) * | 2001-11-21 | 2003-06-10 | Novartis Ag | Composition for stabilizing hyaluronic acid |
| US20040115160A1 (en) * | 2002-12-13 | 2004-06-17 | Salamone Joseph C. | Quaternary ammonium esters for disinfection and preservation |
| US20050084468A1 (en) * | 2003-10-17 | 2005-04-21 | Colgate-Palmolive Company | Antimicrobial cleaning composition |
| TWI454286B (zh) | 2006-03-17 | 2014-10-01 | Johnson & Johnson Vision Care | 安定氧化性不安定組合物之方法 |
| JP5160757B2 (ja) * | 2006-09-01 | 2013-03-13 | ホーユー株式会社 | 毛髪脱染剤組成物 |
| TWI394564B (zh) * | 2006-09-21 | 2013-05-01 | Alcon Res Ltd | 自行保存型水性藥學組成物 |
| WO2008036855A2 (en) * | 2006-09-21 | 2008-03-27 | Alcon Research, Ltd. | Self-preserved aqueous pharmaceutical compositions |
| PL2066300T5 (pl) * | 2006-09-28 | 2020-03-31 | Novartis Ag | Samokonserwujące wodne kompozycje farmaceutyczne |
| JP5216596B2 (ja) * | 2006-10-26 | 2013-06-19 | 千寿製薬株式会社 | 眼科用水性液剤 |
| WO2008121199A2 (en) | 2007-03-28 | 2008-10-09 | University Of Iowa Research Foundation | Transgenic animal models of disease |
| US8759321B2 (en) | 2007-06-13 | 2014-06-24 | Bausch & Lomb Incorporated | Ophthalmic composition with hyaluronic acid and polymeric biguanide |
| US8119112B2 (en) | 2008-01-31 | 2012-02-21 | Bausch & Lomb Incorporated | Ophthalmic compositions with an amphoteric surfactant and hyaluronic acid |
| PL2254549T5 (pl) * | 2008-03-17 | 2019-12-31 | Alcon Research, Ltd. | Wodne kompozycje farmaceutyczne zawierające kompleksy boran-poliole |
| US8299079B2 (en) | 2009-05-22 | 2012-10-30 | Kaufman Herbert E | Preparations and methods for ameliorating or reducing presbyopia |
| WO2010135731A1 (en) * | 2009-05-22 | 2010-11-25 | Kaufman Herbert E | Preparations and methods for ameliorating or reducing presbyopia |
| TWI489997B (zh) | 2009-06-19 | 2015-07-01 | Alcon Res Ltd | 含有硼酸-多元醇錯合物之水性藥學組成物 |
| PT2709445T (pt) | 2011-05-16 | 2018-11-27 | Univ Missouri | Animais resistentes ao vírus da síntese reprodutiva e respiratória porcino |
| US9661831B2 (en) | 2011-11-03 | 2017-05-30 | University Of Iowa Research Foundation | Transgenic pig models of cystic fibrosis |
| US20130177599A1 (en) * | 2012-01-06 | 2013-07-11 | Insite Vision Incorporated | Methods and kits for extending contact lens use |
| KR101400791B1 (ko) | 2012-10-04 | 2014-05-29 | 주식회사대성미생물연구소 | 동물용 복합 기능성 항생제 조성물 |
| WO2016187426A1 (en) | 2015-05-19 | 2016-11-24 | Amorphex Therapeutics Llc | A device that delivers a sustained low-dose of a myopia-suppressing drug |
| US10231961B1 (en) | 2017-02-07 | 2019-03-19 | Genus Lifesciences Inc. | Pharmaceutical compositions and methods of using the same |
| US10413505B1 (en) | 2017-02-07 | 2019-09-17 | Genus Lifesciences Inc. | Pharmaceutical compositions and methods of using the same |
| US10149843B1 (en) | 2017-02-07 | 2018-12-11 | Gneus Lifescineces Inc. | Pharmaceutical compositions and methods of using the same |
| CN109387622A (zh) * | 2018-03-02 | 2019-02-26 | 国家纳米科学中心 | 一种高分子材料表面修饰方法及其应用 |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2322883A1 (de) * | 1973-05-07 | 1974-11-28 | Roehm Gmbh | Wasserloesliche polymerisate |
| DE2743764C2 (de) * | 1977-09-29 | 1982-07-22 | Hoechst Ag, 6000 Frankfurt | Wäßrige Kunststoffdispersion auf Basis von Vinylpolymeren |
| DE2810348A1 (de) * | 1978-03-10 | 1979-09-20 | Hoechst Ag | Waessrige kunststoffdispersion auf basis von vinylpolymeren |
| US4303568A (en) * | 1979-12-10 | 1981-12-01 | Betz Laboratories, Inc. | Corrosion inhibition treatments and method |
| US4474916A (en) * | 1982-07-27 | 1984-10-02 | Basf Aktiengesellschaft | Concentrated aqueous solutions of mixtures of organic complexing agents and dispersing agents based on polymeric aliphatic carboxylic acids |
| ATE151286T1 (de) * | 1983-11-14 | 1997-04-15 | Columbia Lab Inc | Bioadhäsive mittel |
| JPS60184013A (ja) * | 1984-03-01 | 1985-09-19 | Yoshitomi Pharmaceut Ind Ltd | 点眼剤 |
| US4540738A (en) * | 1984-12-07 | 1985-09-10 | The Kendall Company | Acrylic adhesive composition comprising an alpha amino phosphonic acid or salt having improved stability |
| US4889689A (en) * | 1986-10-14 | 1989-12-26 | Ciba-Geigy Corporation | Method of disinfecting a soft contact lens with a diethylene triamine penta(methylenephosphonic acid) stabilized hydrogen peroxide solution |
| US4900469A (en) * | 1986-10-21 | 1990-02-13 | The Clorox Company | Thickened peracid precursor compositions |
| US4812173A (en) * | 1987-05-01 | 1989-03-14 | Ciba-Geigy Corporation | Stabilized hydrogen peroxide contact lens disinfecting solution |
| US5192535A (en) * | 1988-02-08 | 1993-03-09 | Insite Vision Incorporated | Ophthalmic suspensions |
| DE3805663A1 (de) * | 1988-02-24 | 1989-09-07 | Henkel Kgaa | Oxaalkanpolyphosphonsaeuren, ihre verwendung als thresholder sowie diese verbindungen enthaltende, komplexierend wirkende zusammensetzungen |
| ATE141803T1 (de) * | 1988-08-04 | 1996-09-15 | Ciba Geigy Ag | Verfahren zur konservierung ophthalmischer lösungen und zusammensetzungen dafür |
| US4960799A (en) * | 1988-09-13 | 1990-10-02 | Ciba-Geigy Corporation | Stabilized aqueous solutions of pharmaceutically acceptable salts of ortho-(2,6-dichlorophenyl)-aminophenylacetic acid for opthalmic use |
| US5075104A (en) * | 1989-03-31 | 1991-12-24 | Alcon Laboratories, Inc. | Ophthalmic carboxy vinyl polymer gel for dry eye syndrome |
| US5034556A (en) * | 1989-04-03 | 1991-07-23 | Ppg Industries, Inc. | Reaction products of alpha-aminomethylene phosphonic acids and epoxy compounds and their use in coating compositions |
| US5300296A (en) * | 1989-11-06 | 1994-04-05 | Frank J. Holly | Antimicrobial agent for opthalmic formulations |
| JP3008131B2 (ja) * | 1990-11-14 | 2000-02-14 | ロレアル | グリセリンから誘導される非イオン両親媒性化合物、その調製方法、相応する中間体化合物及び前記化合物を含有する組成物 |
| EP0564510A1 (en) * | 1990-12-27 | 1993-10-13 | Allergan, Inc | Method and composition for disinfecting contact lenses |
| JP3107873B2 (ja) * | 1991-09-26 | 2000-11-13 | ユニ・チャーム株式会社 | 高吸水性ポリマーの経時着色防止方法および経時着色防止剤 |
| ES2087437T3 (es) * | 1991-11-26 | 1996-07-16 | Eniricerche Spa | Composicion gelificable acuosa que contiene un agente antisineresis. |
| JP2873530B2 (ja) * | 1991-12-13 | 1999-03-24 | 参天製薬株式会社 | ニュートン型粘性を示すカルボキシビニルポリマー含有点眼液基剤 |
| DE4209722C3 (de) * | 1992-03-25 | 1997-06-19 | Medproject Pharma Entwicklungs | Tropfbares Gel für die Augenheilkunde |
| SE500660C2 (sv) * | 1992-12-03 | 1994-08-01 | Mo Och Domsjoe Ab | Förfarande för framställning av grönlut vid kemikalieåtervinning i sulfat- och sulfitmassafabriker |
| US5340572A (en) * | 1993-02-08 | 1994-08-23 | Insite Vision Incorporated | Alkaline ophthalmic suspensions |
| DE59407521D1 (de) * | 1993-08-10 | 1999-02-04 | Ciba Geigy Ag | Mercerisiernetzmittel |
| FR2726762B1 (fr) * | 1994-11-10 | 1997-01-17 | Oreal | Composition cosmetique ou dermatologique sous forme d'une dispersion d'une phase huileuse dans une phase aqueuse stabilisee a l'aide de particules de gel cubique et son procede d'obtention |
| US5603929A (en) * | 1994-11-16 | 1997-02-18 | Alcon Laboratories, Inc. | Preserved ophthalmic drug compositions containing polymeric quaternary ammonium compounds |
-
1995
- 1995-06-22 US US08/493,761 patent/US5683993A/en not_active Expired - Lifetime
- 1995-12-27 TW TW084113926A patent/TW358109B/zh not_active IP Right Cessation
-
1996
- 1996-06-12 DK DK96922797T patent/DK0833609T3/da active
- 1996-06-12 EP EP96922797A patent/EP0833609B1/en not_active Expired - Lifetime
- 1996-06-12 ES ES96922797T patent/ES2167581T3/es not_active Expired - Lifetime
- 1996-06-12 AU AU63551/96A patent/AU715686B2/en not_active Ceased
- 1996-06-12 CA CA002222646A patent/CA2222646C/en not_active Expired - Fee Related
- 1996-06-12 PT PT96922797T patent/PT833609E/pt unknown
- 1996-06-12 AT AT96922797T patent/ATE208189T1/de active
- 1996-06-12 DE DE69616791T patent/DE69616791T2/de not_active Expired - Lifetime
- 1996-06-12 WO PCT/EP1996/002539 patent/WO1997000669A1/en not_active Ceased
- 1996-06-12 JP JP50343097A patent/JP4260881B2/ja not_active Expired - Fee Related
-
1997
- 1997-05-27 US US08/863,855 patent/US5858996A/en not_active Expired - Lifetime
-
2003
- 2003-04-30 CY CY0300035A patent/CY2323B1/xx unknown
-
2008
- 2008-03-21 JP JP2008072839A patent/JP2008248246A/ja active Pending
-
2012
- 2012-04-09 JP JP2012088780A patent/JP2012153710A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP2008248246A (ja) | 2008-10-16 |
| US5683993A (en) | 1997-11-04 |
| JP4260881B2 (ja) | 2009-04-30 |
| JP2012153710A (ja) | 2012-08-16 |
| DK0833609T3 (da) | 2002-02-18 |
| AU715686B2 (en) | 2000-02-10 |
| JPH11510480A (ja) | 1999-09-14 |
| DE69616791D1 (de) | 2001-12-13 |
| PT833609E (pt) | 2002-04-29 |
| DE69616791T2 (de) | 2002-05-29 |
| CA2222646C (en) | 2009-12-08 |
| WO1997000669A1 (en) | 1997-01-09 |
| US5858996A (en) | 1999-01-12 |
| EP0833609B1 (en) | 2001-11-07 |
| CY2323B1 (en) | 2003-11-14 |
| ES2167581T3 (es) | 2002-05-16 |
| ATE208189T1 (de) | 2001-11-15 |
| AU6355196A (en) | 1997-01-22 |
| CA2222646A1 (en) | 1997-01-09 |
| EP0833609A1 (en) | 1998-04-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | Annulment or lapse of patent due to non-payment of fees |