TW250482B - - Google Patents
Info
- Publication number
- TW250482B TW250482B TW081109861A TW81109861A TW250482B TW 250482 B TW250482 B TW 250482B TW 081109861 A TW081109861 A TW 081109861A TW 81109861 A TW81109861 A TW 81109861A TW 250482 B TW250482 B TW 250482B
- Authority
- TW
- Taiwan
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
- C07H13/06—Fatty acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US77610091A | 1991-10-11 | 1991-10-11 | |
| US07/935,050 US5530113A (en) | 1991-10-11 | 1992-08-25 | Anti-endotoxin compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TW250482B true TW250482B (enExample) | 1995-07-01 |
Family
ID=25106455
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW081109861A TW250482B (enExample) | 1991-10-11 | 1992-12-09 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US5530113A (enExample) |
| KR (1) | KR930007942A (enExample) |
| TW (1) | TW250482B (enExample) |
| ZA (1) | ZA927751B (enExample) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5648343A (en) * | 1994-02-28 | 1997-07-15 | The University Of Georgia Research Foundation | Method for treating LPS-mediated disorders |
| US6417172B1 (en) * | 1995-06-05 | 2002-07-09 | Eisai Co., Ltd. | Prevention and treatment of pulmonary bacterial infection or symptomatic pulmonary exposure to endotoxin by inhalation of antiendotoxin drugs |
| US5750664A (en) * | 1995-06-05 | 1998-05-12 | Eisai Co., Ltd. | Substituted liposaccharides useful in the treatment and prevention of endotoxemia |
| AU7254396A (en) * | 1995-09-29 | 1997-04-17 | Eisai Research Institute | Method for treating alcoholic liver disease |
| EP0909562B1 (en) * | 1996-07-03 | 2005-06-29 | Eisai Co., Ltd. | Injections containing lipid a analogues and process for the preparation thereof |
| US6172220B1 (en) | 1997-01-21 | 2001-01-09 | Board Of Regents Of University Of Nebraska | Isolated algal lipopolysaccharides and use of same to inhibit endotoxin-initiated sepsis |
| US6444654B1 (en) | 1997-01-21 | 2002-09-03 | Board Of Regents Of University Of Nebraska | Isolated asgal lipopolysaccharides and use of same to inhibit innate immune response |
| CA2301943C (en) * | 1997-08-29 | 2008-11-04 | The Johns Hopkins University | Antimicrobial compounds |
| AU2003200765B2 (en) * | 1997-08-29 | 2007-01-25 | The Johns Hopkins University | Antimicrobial compounds |
| US6713654B1 (en) * | 1997-08-29 | 2004-03-30 | The Johns Hopkins University School Of Medicine | Antimicrobial compounds |
| US6011066A (en) * | 1998-02-02 | 2000-01-04 | Veterans General Hospital-Taipei | Method for treating septic shock |
| DE60036790T2 (de) | 1999-01-14 | 2008-07-24 | Eisai R&D Management Co., Ltd. | Verwendung von e5564 zur behandlung von sepsis durch intravenöse infusion |
| US20040006242A1 (en) | 1999-02-01 | 2004-01-08 | Hawkins Lynn D. | Immunomodulatory compounds and method of use thereof |
| AU2008202882B2 (en) * | 1999-02-01 | 2011-06-16 | Eisai R & D Management Co., Ltd. | Immunological adjuvant compound |
| EP2452684B1 (en) | 2000-02-18 | 2018-01-24 | Eisai R&D Management Co., Ltd. | Micelles |
| WO2002085117A1 (en) * | 2001-04-24 | 2002-10-31 | Eisai Co., Ltd. | Methods and compositions for preventing and treating septic shock and endotoxemia |
| WO2003013440A2 (en) | 2001-08-10 | 2003-02-20 | Eisai Co., Ltd. | Treatment and prevention of heat shock protein-associated diseases and conditions |
| AU2003242470A1 (en) * | 2002-06-18 | 2003-12-31 | Sankyo Company, Limited | 1-carboxymethyl analogues of glucosyl lipid a |
| MXPA05007295A (es) | 2003-01-06 | 2005-09-30 | Corixa Corp | Ciertos compuestos de fosfato de aminoalquil glucosaminida y su uso. |
| US7960522B2 (en) | 2003-01-06 | 2011-06-14 | Corixa Corporation | Certain aminoalkyl glucosaminide phosphate compounds and their use |
| US7951232B2 (en) * | 2006-02-09 | 2011-05-31 | Elevance Renewable Sciences, Inc. | Surface coating compositions and methods |
| CN101969771A (zh) * | 2006-02-09 | 2011-02-09 | 埃莱文斯可更新科学公司 | 抗微生物组合物、方法和体系 |
| PT2486938T (pt) | 2006-09-26 | 2018-06-12 | Infectious Disease Res Inst | Composição para vacina contendo adjuvante sintético |
| US20090181078A1 (en) | 2006-09-26 | 2009-07-16 | Infectious Disease Research Institute | Vaccine composition containing synthetic adjuvant |
| US8563523B2 (en) * | 2007-09-07 | 2013-10-22 | University Of Georgia Research Foundation, Inc. | Synthetic lipid A derivative |
| LT2437753T (lt) * | 2009-06-05 | 2016-12-12 | Infectious Disease Research Institute | Sintetiniai gliukopiranozillipidų adjuvantai ir juos turinčios vakcinų kompozicijos |
| EP2537523B1 (en) | 2010-02-16 | 2016-03-30 | TFK Co., Ltd | Prophylactic/ameliorating agent for diseases, endurance improving agent and anti-fatigue agent, and pharmaceutical agent, food and beverage each comprising any one of those agents |
| CN103596586A (zh) | 2011-04-08 | 2014-02-19 | 免疫设计公司 | 免疫原性组合物及使用所述组合物诱导体液和细胞免疫反应的方法 |
| HRP20181102T1 (hr) | 2012-05-16 | 2018-09-07 | Immune Design Corp | Cjepiva za hsv-2 |
| HK1214510A1 (zh) | 2013-04-18 | 2016-07-29 | Immune Design Corp. | 用於癌症治疗的gla单一疗法 |
| US9463198B2 (en) | 2013-06-04 | 2016-10-11 | Infectious Disease Research Institute | Compositions and methods for reducing or preventing metastasis |
| FI3752182T3 (fi) | 2018-02-12 | 2024-07-30 | Inimmune Corp | Tollin kaltaisen reseptorin ligandeja |
| EP3897665A4 (en) | 2018-12-17 | 2022-09-28 | Eisai R&D Management Co., Ltd. | FORMULATION INCLUDING LIPOSOMES |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4495346A (en) * | 1981-03-30 | 1985-01-22 | Wisconsin Alumni Research Foundation | Method of preparing a disaccharide |
| US5057598A (en) * | 1983-05-06 | 1991-10-15 | Centocor, Inc. | Monoclonal antibodies reactive with endotoxin core |
| US4844894A (en) * | 1984-07-12 | 1989-07-04 | Ribi Immunochem Research Inc. | Method of inhibiting the onset of septicemia and endotoxemia |
| US4629722A (en) * | 1984-07-12 | 1986-12-16 | Ribi Immunochem Research, Inc. | Method of inhibiting the onset of acute radiation syndrome |
| JPS6153295A (ja) * | 1984-08-24 | 1986-03-17 | Dai Ichi Seiyaku Co Ltd | ジサツカライド誘導体 |
| US5066794A (en) * | 1984-08-24 | 1991-11-19 | Daiichi Pharmaceutical Co., Ltd. | Process for preparing a disaccharide derivative |
| HU199494B (en) * | 1985-06-28 | 1990-02-28 | Sandoz Ag | Process for producing new saccharides and pharmaceutical compositions comprising same |
| US4918163A (en) * | 1985-09-27 | 1990-04-17 | Pfizer Inc. | Monoclonal antibodies specific for lipid-A determinants of gram negative bacteria |
| US4877611A (en) * | 1986-04-15 | 1989-10-31 | Ribi Immunochem Research Inc. | Vaccine containing tumor antigens and adjuvants |
| US4929604A (en) * | 1986-05-28 | 1990-05-29 | Board Of Regents, The University Of Texas System | Lipopolysaccharides of reduced toxicity and the production thereof |
| JP2535048B2 (ja) * | 1988-02-29 | 1996-09-18 | 第一製薬株式会社 | 新規ジサッカライド誘導体及びその塩 |
| US5134230A (en) * | 1988-03-02 | 1992-07-28 | Daiichi Pharmaceutical Co., Ltd. | 2-Deoxy-2-aminoglucopyranoside derivatives |
| ZA881430B (enExample) * | 1988-03-02 | 1988-10-28 | ||
| US4912094B1 (en) * | 1988-06-29 | 1994-02-15 | Ribi Immunochem Research Inc. | Modified lipopolysaccharides and process of preparation |
| US5041427A (en) * | 1989-07-21 | 1991-08-20 | Wisconsin Alumni Research Foundation | Lipid A derivatives |
| US5158939A (en) * | 1989-07-21 | 1992-10-27 | Wisconsin Alumni Research Foundation | Method of stimulating the immune systems of animals and compositions useful therefor |
| JPH0655749B2 (ja) * | 1989-09-20 | 1994-07-27 | 日本たばこ産業株式会社 | リピッドａ単糖類縁体 |
| JP2839916B2 (ja) * | 1989-10-20 | 1998-12-24 | 三共株式会社 | リピドａ３位エーテル類縁体 |
| US5158941A (en) * | 1990-06-08 | 1992-10-27 | E. I. Du Pont De Nemours And Company | Lipid A analog as stimulant for production of interleukin-1 in human monocytes and tumor cell growth inhibitor |
| AU660325B2 (en) * | 1991-10-11 | 1995-06-22 | Eisai Co. Ltd. | Anti-endotoxin compounds and related molecules and methods |
-
1992
- 1992-08-25 US US07/935,050 patent/US5530113A/en not_active Expired - Lifetime
- 1992-10-08 ZA ZA927751A patent/ZA927751B/xx unknown
- 1992-10-09 KR KR1019920018710A patent/KR930007942A/ko not_active Ceased
- 1992-12-09 TW TW081109861A patent/TW250482B/zh active
Also Published As
| Publication number | Publication date |
|---|---|
| US5530113A (en) | 1996-06-25 |
| ZA927751B (en) | 1993-06-10 |
| KR930007942A (ko) | 1993-05-20 |