TW202515596A - 用於抑制認知功能下降或改善認知功能之組成物，及用於阻礙β－分泌酶之組成物 - Google Patents

用於抑制認知功能下降或改善認知功能之組成物，及用於阻礙β－分泌酶之組成物 Download PDF

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Publication number
TW202515596A
TW202515596A TW113122523A TW113122523A TW202515596A TW 202515596 A TW202515596 A TW 202515596A TW 113122523 A TW113122523 A TW 113122523A TW 113122523 A TW113122523 A TW 113122523A TW 202515596 A TW202515596 A TW 202515596A
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TW
Taiwan
Prior art keywords
cyclo
composition
phe
inhibiting
arg
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TW113122523A
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English (en)
Chinese (zh)
Inventor
善美 楊
振杰 劉
晶晶 姚
加藤寛之
古元義
Original Assignee
日商三得利控股股份有限公司
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Application filed by 日商三得利控股股份有限公司 filed Critical 日商三得利控股股份有限公司
Publication of TW202515596A publication Critical patent/TW202515596A/zh

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    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/18—Peptides; Protein hydrolysates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/05—Dipeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/12—Cyclic peptides with only normal peptide bonds in the ring

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Polymers & Plastics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Food Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • Nutrition Science (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
TW113122523A 2023-06-19 2024-06-18 用於抑制認知功能下降或改善認知功能之組成物，及用於阻礙β－分泌酶之組成物 TW202515596A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2023099982 2023-06-19
JP2023-099982 2023-06-19

Publications (1)

Publication Number Publication Date
TW202515596A true TW202515596A (zh) 2025-04-16

Family

ID=93935282

Family Applications (1)

Application Number Title Priority Date Filing Date
TW113122523A TW202515596A (zh) 2023-06-19 2024-06-18 用於抑制認知功能下降或改善認知功能之組成物，及用於阻礙β－分泌酶之組成物

Country Status (3)

Country Link
JP (1) JPWO2024262349A1 (https=)
TW (1) TW202515596A (https=)
WO (1) WO2024262349A1 (https=)

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7202279B1 (en) * 1998-02-11 2007-04-10 Georgetown University Cyclic dipeptides and azetidinone compounds and their use in treating CNS injury and neurodegenerative disorders
WO2015194070A1 (ja) * 2014-06-20 2015-12-23 サントリーホールディングス株式会社 環状ジペプチド高含有組成物
JP6684277B2 (ja) * 2015-07-01 2020-04-22 サントリーホールディングス株式会社 レニン−アンジオテンシン系抑制用組成物
WO2017010133A1 (ja) * 2015-07-16 2017-01-19 サントリーホールディングス株式会社 動植物由来ペプチド含有血清カルノシン分解酵素阻害用組成物
WO2017010537A1 (ja) * 2015-07-16 2017-01-19 サントリーホールディングス株式会社 環状ジペプチド含有血清カルノシン分解酵素阻害用組成物
JP6719475B2 (ja) * 2015-09-04 2020-07-08 サントリーホールディングス株式会社 ウレアーゼ活性阻害剤
WO2017115438A1 (ja) * 2015-12-28 2017-07-06 サントリーホールディングス株式会社 ビールテイスト飲料
WO2017119481A1 (ja) * 2016-01-08 2017-07-13 サントリーホールディングス株式会社 環状ジペプチド含有神経性疾患予防用組成物
WO2017119476A1 (ja) * 2016-01-08 2017-07-13 サントリーホールディングス株式会社 神経性疾患予防用組成物
JP6598412B1 (ja) * 2019-06-04 2019-10-30 ゼライス株式会社 認知機能改善用食品
WO2022131026A1 (en) * 2020-12-18 2022-06-23 Suntory Holdings Limited Use of cyclic dipeptides in production of agent for inhibiting decline in cognitive function or ameliorating cognitive dysfunction
AU2022420239A1 (en) * 2021-12-23 2024-07-11 Suntory Holdings Limited Composition for suppressing or ameliorating cognitive function decline

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JPWO2024262349A1 (https=) 2024-12-26
WO2024262349A1 (ja) 2024-12-26

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