TW202502767A - 喹啉取代化合物之結晶 - Google Patents

喹啉取代化合物之結晶 Download PDF

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Publication number
TW202502767A
TW202502767A TW113120087A TW113120087A TW202502767A TW 202502767 A TW202502767 A TW 202502767A TW 113120087 A TW113120087 A TW 113120087A TW 113120087 A TW113120087 A TW 113120087A TW 202502767 A TW202502767 A TW 202502767A
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TW
Taiwan
Prior art keywords
crystal
compound
crystals
type
methyl
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TW113120087A
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English (en)
Chinese (zh)
Inventor
宇野貴夫
武田大典
Original Assignee
日商大鵬藥品工業股份有限公司
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Application filed by 日商大鵬藥品工業股份有限公司 filed Critical 日商大鵬藥品工業股份有限公司
Publication of TW202502767A publication Critical patent/TW202502767A/zh

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
TW113120087A 2023-05-31 2024-05-30 喹啉取代化合物之結晶 TW202502767A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2023-090561 2023-05-31
JP2023090561 2023-05-31

Publications (1)

Publication Number Publication Date
TW202502767A true TW202502767A (zh) 2025-01-16

Family

ID=93658111

Family Applications (1)

Application Number Title Priority Date Filing Date
TW113120087A TW202502767A (zh) 2023-05-31 2024-05-30 喹啉取代化合物之結晶

Country Status (5)

Country Link
EP (1) EP4722218A1 (https=)
JP (1) JPWO2024248083A1 (https=)
CN (1) CN121285557A (https=)
TW (1) TW202502767A (https=)
WO (1) WO2024248083A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025141465A1 (en) 2023-12-27 2025-07-03 Assia Chemical Industries Ltd. Solid state forms of zipalertinib hydrochloride and process for preparation thereof
WO2025167588A1 (zh) * 2024-02-05 2025-08-14 苏州科睿思制药有限公司 Zipalertinib的晶型及其制备方法和用途

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112016003247B1 (pt) 2013-08-22 2022-05-10 Taiho Pharmaceutical Co., Ltd Composto substituído por quinolina, composição farmacêutica compreendendo o referido composto e seu uso
JP2018002644A (ja) * 2016-06-30 2018-01-11 大鵬薬品工業株式会社 （Ｓ）−Ｎ−（４−アミノ−５−（キノリン−３−イル）−６，７，８，９−テトラヒドロピリミド［５，４−ｂ］インドリジン−８−イル）アクリルアミドの結晶
WO2022121967A1 (zh) * 2020-12-09 2022-06-16 南京药石科技股份有限公司 Egfr酪氨酸激酶抑制剂及其用途
CN115707704B (zh) * 2021-08-20 2024-09-13 广东医诺维申生物技术有限公司 氘代稠合三环类化合物及其组合物和用途
JP2025538804A (ja) * 2022-12-08 2025-11-28 アッシア ケミカル インダストリーズ リミテッド ジパレルチニブの固体状態の形態及びそれを調製するための方法
CN115785107B (zh) * 2022-12-15 2024-11-12 南京雷正医药科技有限公司 一种取代8,9-二氢嘧啶并[5,4-b]吲嗪类化合物、药物组合物及其用途

Also Published As

Publication number Publication date
WO2024248083A1 (ja) 2024-12-05
JPWO2024248083A1 (https=) 2024-12-05
CN121285557A (zh) 2026-01-06
EP4722218A1 (en) 2026-04-08

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