TW202430203A - 用於處置或預防眼科疾病的環狀胜肽衍生物組成物 - Google Patents

用於處置或預防眼科疾病的環狀胜肽衍生物組成物 Download PDF

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Publication number
TW202430203A
TW202430203A TW112137716A TW112137716A TW202430203A TW 202430203 A TW202430203 A TW 202430203A TW 112137716 A TW112137716 A TW 112137716A TW 112137716 A TW112137716 A TW 112137716A TW 202430203 A TW202430203 A TW 202430203A
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TW
Taiwan
Prior art keywords
group
hydrogen atom
composition
mmol
alkyl group
Prior art date
Application number
TW112137716A
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English (en)
Chinese (zh)
Inventor
松本恒平
大西海斗
寺上佳奈
苅田祐馬
田部七大
安井航佑
正司武嗣
Original Assignee
日商第一工業製藥股份有限公司
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Application filed by 日商第一工業製藥股份有限公司 filed Critical 日商第一工業製藥股份有限公司
Publication of TW202430203A publication Critical patent/TW202430203A/zh

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
TW112137716A 2022-09-30 2023-10-02 用於處置或預防眼科疾病的環狀胜肽衍生物組成物 TW202430203A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2022159075 2022-09-30
JP2022-159075 2022-09-30

Publications (1)

Publication Number Publication Date
TW202430203A true TW202430203A (zh) 2024-08-01

Family

ID=90478092

Family Applications (1)

Application Number Title Priority Date Filing Date
TW112137716A TW202430203A (zh) 2022-09-30 2023-10-02 用於處置或預防眼科疾病的環狀胜肽衍生物組成物

Country Status (8)

Country Link
US (1) US20260091082A1 (https=)
EP (1) EP4595973A1 (https=)
JP (1) JPWO2024071370A1 (https=)
KR (1) KR20250077478A (https=)
CN (1) CN119947740A (https=)
IL (1) IL319591A (https=)
TW (1) TW202430203A (https=)
WO (1) WO2024071370A1 (https=)

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4172896A (en) 1978-06-05 1979-10-30 Dainippon Pharmaceutical Co., Ltd. Methane-sulfonamide derivatives, the preparation thereof and composition comprising the same
GB9217295D0 (en) 1992-08-14 1992-09-30 Wellcome Found Controlled released tablets
US5541231A (en) 1993-07-30 1996-07-30 Glaxo Wellcome Inc. Stabilized Pharmaceutical
GB9315856D0 (en) 1993-07-30 1993-09-15 Wellcome Found Stabilized pharmaceutical
US5358970A (en) 1993-08-12 1994-10-25 Burroughs Wellcome Co. Pharmaceutical composition containing bupropion hydrochloride and a stabilizer
DE69839355T2 (de) 1997-07-29 2009-06-04 Alcon Laboratories, Inc., Fort Worth Ophthalmische Zusammensetzungen enthaltend Galaktomannanpolymere und Borat
AU2483599A (en) 1998-01-29 1999-08-16 Sepracor, Inc. Pharmaceutical uses of optically pure (-)-bupropion
US8889112B2 (en) 1999-09-16 2014-11-18 Ocularis Pharma, Llc Ophthalmic formulations including selective alpha 1 antagonists
US6933289B2 (en) 2003-07-01 2005-08-23 Allergan, Inc. Inhibition of irritating side effects associated with use of a topical ophthalmic medication
EP1654002B2 (en) 2003-08-07 2014-01-29 Allergan, Inc. Compositions for delivery of therapeutics into the eyes
US20050059744A1 (en) 2003-09-12 2005-03-17 Allergan, Inc. Methods and compositions for the treatment of pain and other alpha 2 adrenergic-mediated conditions
WO2016047638A1 (ja) * 2014-09-24 2016-03-31 国立大学法人岩手大学 環状ペプチド誘導体とその製造方法および組成物
JP7486328B2 (ja) * 2020-03-05 2024-05-17 株式会社バイオコクーン研究所 神経突起伸長促進剤、神経細胞の樹状突起発現促進剤、及び神経栄養因子様作用物質
JP7695662B2 (ja) * 2020-11-02 2025-06-19 公立大学法人大阪 環状ペプチド誘導体の製造方法及び環状ペプチド化合物の製造方法

Also Published As

Publication number Publication date
WO2024071370A1 (ja) 2024-04-04
CN119947740A (zh) 2025-05-06
EP4595973A1 (en) 2025-08-06
KR20250077478A (ko) 2025-05-30
US20260091082A1 (en) 2026-04-02
IL319591A (en) 2025-05-01
JPWO2024071370A1 (https=) 2024-04-04

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