KR20250077478A - 안과 질환을 처치 또는 예방하기 위한 고리형 펩티드 유도체 조성물 - Google Patents

안과 질환을 처치 또는 예방하기 위한 고리형 펩티드 유도체 조성물 Download PDF

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Publication number
KR20250077478A
KR20250077478A KR1020257008352A KR20257008352A KR20250077478A KR 20250077478 A KR20250077478 A KR 20250077478A KR 1020257008352 A KR1020257008352 A KR 1020257008352A KR 20257008352 A KR20257008352 A KR 20257008352A KR 20250077478 A KR20250077478 A KR 20250077478A
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KR
South Korea
Prior art keywords
group
hydrogen atom
composition
mmol
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
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KR1020257008352A
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English (en)
Korean (ko)
Inventor
고헤이 마츠모토
가이토 오니시
가나 데라가미
유마 가리타
시치다이 다나베
고스케 야스이
다케시 쇼스
Original Assignee
다이이치 고교 세이야쿠 가부시키가이샤
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Publication of KR20250077478A publication Critical patent/KR20250077478A/ko
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020257008352A 2022-09-30 2023-09-29 안과 질환을 처치 또는 예방하기 위한 고리형 펩티드 유도체 조성물 Pending KR20250077478A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2022159075 2022-09-30
JPJP-P-2022-159075 2022-09-30
PCT/JP2023/035591 WO2024071370A1 (ja) 2022-09-30 2023-09-29 眼科疾患を処置または予防するための環状ペプチド誘導体組成物

Publications (1)

Publication Number Publication Date
KR20250077478A true KR20250077478A (ko) 2025-05-30

Family

ID=90478092

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020257008352A Pending KR20250077478A (ko) 2022-09-30 2023-09-29 안과 질환을 처치 또는 예방하기 위한 고리형 펩티드 유도체 조성물

Country Status (8)

Country Link
US (1) US20260091082A1 (https=)
EP (1) EP4595973A1 (https=)
JP (1) JPWO2024071370A1 (https=)
KR (1) KR20250077478A (https=)
CN (1) CN119947740A (https=)
IL (1) IL319591A (https=)
TW (1) TW202430203A (https=)
WO (1) WO2024071370A1 (https=)

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4172896A (en) 1978-06-05 1979-10-30 Dainippon Pharmaceutical Co., Ltd. Methane-sulfonamide derivatives, the preparation thereof and composition comprising the same
GB9217295D0 (en) 1992-08-14 1992-09-30 Wellcome Found Controlled released tablets
US5541231A (en) 1993-07-30 1996-07-30 Glaxo Wellcome Inc. Stabilized Pharmaceutical
GB9315856D0 (en) 1993-07-30 1993-09-15 Wellcome Found Stabilized pharmaceutical
US5358970A (en) 1993-08-12 1994-10-25 Burroughs Wellcome Co. Pharmaceutical composition containing bupropion hydrochloride and a stabilizer
DE69839355T2 (de) 1997-07-29 2009-06-04 Alcon Laboratories, Inc., Fort Worth Ophthalmische Zusammensetzungen enthaltend Galaktomannanpolymere und Borat
AU2483599A (en) 1998-01-29 1999-08-16 Sepracor, Inc. Pharmaceutical uses of optically pure (-)-bupropion
US8889112B2 (en) 1999-09-16 2014-11-18 Ocularis Pharma, Llc Ophthalmic formulations including selective alpha 1 antagonists
US6933289B2 (en) 2003-07-01 2005-08-23 Allergan, Inc. Inhibition of irritating side effects associated with use of a topical ophthalmic medication
EP1654002B2 (en) 2003-08-07 2014-01-29 Allergan, Inc. Compositions for delivery of therapeutics into the eyes
US20050059744A1 (en) 2003-09-12 2005-03-17 Allergan, Inc. Methods and compositions for the treatment of pain and other alpha 2 adrenergic-mediated conditions
WO2016047638A1 (ja) * 2014-09-24 2016-03-31 国立大学法人岩手大学 環状ペプチド誘導体とその製造方法および組成物
JP7486328B2 (ja) * 2020-03-05 2024-05-17 株式会社バイオコクーン研究所 神経突起伸長促進剤、神経細胞の樹状突起発現促進剤、及び神経栄養因子様作用物質
JP7695662B2 (ja) * 2020-11-02 2025-06-19 公立大学法人大阪 環状ペプチド誘導体の製造方法及び環状ペプチド化合物の製造方法

Also Published As

Publication number Publication date
WO2024071370A1 (ja) 2024-04-04
CN119947740A (zh) 2025-05-06
EP4595973A1 (en) 2025-08-06
US20260091082A1 (en) 2026-04-02
IL319591A (en) 2025-05-01
TW202430203A (zh) 2024-08-01
JPWO2024071370A1 (https=) 2024-04-04

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Date Code Title Description
PA0105 International application

Patent event date: 20250313

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application