TW202345829A - 戊苯那嗪（valbenazine）於治療精神分裂症或情感性精神分裂症之用途 - Google Patents

戊苯那嗪（valbenazine）於治療精神分裂症或情感性精神分裂症之用途 Download PDF

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Publication number
TW202345829A
TW202345829A TW112107002A TW112107002A TW202345829A TW 202345829 A TW202345829 A TW 202345829A TW 112107002 A TW112107002 A TW 112107002A TW 112107002 A TW112107002 A TW 112107002A TW 202345829 A TW202345829 A TW 202345829A
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Taiwan
Prior art keywords
pyrido
isobutyl
hexahydro
isoquinolin
acid
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TW112107002A
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English (en)
Chinese (zh)
Inventor
克里斯多福 F 歐布萊恩
迪米崔 Ｅ 葛里高力亞迪斯
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美商紐羅克里生物科學有限公司
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Publication of TW202345829A publication Critical patent/TW202345829A/zh

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
TW112107002A 2016-12-02 2017-12-01 戊苯那嗪（valbenazine）於治療精神分裂症或情感性精神分裂症之用途 TW202345829A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662429652P 2016-12-02 2016-12-02
US62/429,652 2016-12-02

Publications (1)

Publication Number Publication Date
TW202345829A true TW202345829A (zh) 2023-12-01

Family

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Family Applications (3)

Application Number Title Priority Date Filing Date
TW113125691A TW202515564A (zh) 2016-12-02 2017-12-01 戊苯那嗪（valbenazine）於治療精神分裂症或情感性精神分裂症之用途
TW112107002A TW202345829A (zh) 2016-12-02 2017-12-01 戊苯那嗪（valbenazine）於治療精神分裂症或情感性精神分裂症之用途
TW106142147A TW201827051A (zh) 2016-12-02 2017-12-01 戊苯那嗪（valbenazine）於治療精神分裂症或情感性精神分裂症之用途

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TW113125691A TW202515564A (zh) 2016-12-02 2017-12-01 戊苯那嗪（valbenazine）於治療精神分裂症或情感性精神分裂症之用途

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TW106142147A TW201827051A (zh) 2016-12-02 2017-12-01 戊苯那嗪（valbenazine）於治療精神分裂症或情感性精神分裂症之用途

Country Status (5)

Country Link
US (2) US20200078352A1 (enExample)
EP (2) EP4400171A3 (enExample)
JP (3) JP2020500875A (enExample)
TW (3) TW202515564A (enExample)
WO (1) WO2018102673A1 (enExample)

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CN110818705A (zh) * 2018-08-14 2020-02-21 苏州鹏旭医药科技有限公司 缬苯那嗪的盐型和相应晶型与其制备方法
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US10940141B1 (en) 2019-08-23 2021-03-09 Neurocrine Biosciences, Inc. Methods for the administration of certain VMAT2 inhibitors
CN112933055B (zh) * 2021-03-23 2023-01-13 安徽九华华源药业有限公司 帕利哌酮胃滞留片及其制备方法
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Also Published As

Publication number Publication date
EP4400171A3 (en) 2024-09-11
JP2023015405A (ja) 2023-01-31
US20210113553A1 (en) 2021-04-22
JP2025071099A (ja) 2025-05-02
TW201827051A (zh) 2018-08-01
WO2018102673A1 (en) 2018-06-07
EP3548027A1 (en) 2019-10-09
TW202515564A (zh) 2025-04-16
EP4400171A2 (en) 2024-07-17
US20200078352A1 (en) 2020-03-12
JP2020500875A (ja) 2020-01-16

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