TW202320864A - 經工程改造之ｃａｓｘ抑制子系統 - Google Patents

經工程改造之ｃａｓｘ抑制子系統

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Publication number
TW202320864A
TW202320864A TW111135799A TW111135799A TW202320864A TW 202320864 A TW202320864 A TW 202320864A TW 111135799 A TW111135799 A TW 111135799A TW 111135799 A TW111135799 A TW 111135799A TW 202320864 A TW202320864 A TW 202320864A
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seq
sequence
gene
domain
grna
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TW111135799A
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Chinese (zh)
Inventor
傑森 費爾南德斯
羅斯 懷特
尚恩 希金斯
莎拉 丹妮
班傑明 奧克斯
埃梅里克 珍 馬里烏斯 查爾斯
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美商斯奎柏治療公司
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Publication of TW202320864A publication Critical patent/TW202320864A/zh

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    • C12N9/22—Ribonucleases [RNase]; Deoxyribonucleases [DNase]
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    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
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    • C12N2310/00—Structure or type of the nucleic acid
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    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14141—Use of virus, viral particle or viral elements as a vector
    • C12N2750/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

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TW111135799A 2021-09-21 2022-09-21 經工程改造之ｃａｓｘ抑制子系統 TW202320864A (zh)

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US202163246543P 2021-09-21 2021-09-21
US63/246,543 2021-09-21
US202263321517P 2022-03-18 2022-03-18
US63/321,517 2022-03-18

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EP (1) EP4405479A2 (enExample)
JP (1) JP2024534523A (enExample)
KR (1) KR20240095525A (enExample)
AU (1) AU2022349627A1 (enExample)
CA (1) CA3231909A1 (enExample)
CL (1) CL2024000835A1 (enExample)
GB (1) GB2625500B (enExample)
IL (1) IL311610A (enExample)
MX (1) MX2024003455A (enExample)
PE (1) PE20240728A1 (enExample)
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