TW202246315A - 對冠狀病毒s蛋白具特異性之化合物及其用途 - Google Patents
對冠狀病毒s蛋白具特異性之化合物及其用途 Download PDFInfo
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- 208000004043 venous thromboembolism Diseases 0.000 claims 1
- 230000003612 virological effect Effects 0.000 claims 1
- 230000003442 weekly effect Effects 0.000 claims 1
- JFCFGYGEYRIEBE-YVLHJLIDSA-N wob38vs2ni Chemical compound CO[C@@H]([C@@]1(O)C[C@H](OC(=O)N1)[C@@H](C)[C@@H]1O[C@@]1(C)[C@@H](OC(=O)[C@H](C)N(C)C(=O)CCC(C)(C)S)CC(=O)N1C)\C=C\C=C(C)\CC2=CC(OC)=C(Cl)C1=C2 JFCFGYGEYRIEBE-YVLHJLIDSA-N 0.000 claims 1
- 230000009286 beneficial effect Effects 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 208000037765 diseases and disorders Diseases 0.000 abstract 1
- 230000005764 inhibitory process Effects 0.000 abstract 1
- 238000006386 neutralization reaction Methods 0.000 abstract 1
- 230000003472 neutralizing effect Effects 0.000 abstract 1
- 102000040430 polynucleotide Human genes 0.000 abstract 1
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- 239000002157 polynucleotide Substances 0.000 abstract 1
Images
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
- C07K16/1002—Coronaviridae
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
- C07K16/1002—Coronaviridae
- C07K16/1003—Severe acute respiratory syndrome coronavirus 2 [SARS‐CoV‐2 or Covid-19]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pulmonology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
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US202163146090P | 2021-02-05 | 2021-02-05 | |
US63/146,090 | 2021-02-05 | ||
US202163151278P | 2021-02-19 | 2021-02-19 | |
US63/151,278 | 2021-02-19 | ||
US202163181467P | 2021-04-29 | 2021-04-29 | |
US63/181,467 | 2021-04-29 | ||
US202163187982P | 2021-05-13 | 2021-05-13 | |
US63/187,982 | 2021-05-13 |
Publications (1)
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TW202246315A true TW202246315A (zh) | 2022-12-01 |
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TW111104400A TW202246315A (zh) | 2021-02-05 | 2022-02-07 | 對冠狀病毒s蛋白具特異性之化合物及其用途 |
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TW (1) | TW202246315A (fr) |
WO (1) | WO2022170126A2 (fr) |
Cited By (1)
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CN114230674A (zh) * | 2020-12-01 | 2022-03-25 | 中国医学科学院基础医学研究所 | 一种含Fc结构域的新型冠状病毒S蛋白受体结合域融合蛋白及其用途 |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
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WO2023154824A1 (fr) * | 2022-02-10 | 2023-08-17 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Anticorps monoclonaux humains ciblant largement les coronavirus |
WO2024036313A2 (fr) * | 2022-08-12 | 2024-02-15 | The Rockefeller University | Anticorps anti-sars-cov-2 et procédés d'utilisation associés |
WO2024076982A2 (fr) * | 2022-10-05 | 2024-04-11 | University Of Washington | Vaccins à nanoparticules de pan-sarbecovirus |
WO2024089277A2 (fr) * | 2022-10-27 | 2024-05-02 | Oxford University Innovation Limited | Anticorps |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
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WO2005035732A2 (fr) * | 2003-02-19 | 2005-04-21 | Dyax Corporation | Ligands de papp-a |
US8008445B2 (en) * | 2008-03-03 | 2011-08-30 | Dyax Corp. | Metalloproteinase 9 binding proteins |
JO3701B1 (ar) * | 2014-05-23 | 2021-01-31 | Regeneron Pharma | مضادات حيوية بشرية لمتلازمة الشرق الأوسط التنفسية - بروتين كورونا فيروس الشوكي |
ES2753551T3 (es) * | 2014-07-22 | 2020-04-13 | Sutro Biopharma Inc | Anticuerpos anti-cd74, composiciones que comprenden anticuerpos anti-CD74 y procedimientos de uso de los anticuerpos anti-CD74 |
IL304950A (en) * | 2015-04-10 | 2023-10-01 | Amgen Inc | Interleukin for the expansion of myotonic control T-2 cells |
BR112019008063A2 (pt) * | 2016-10-21 | 2019-07-02 | Adimab Llc | anticorpos contra o vírus sincicial anti-respiratório e métodos de sua geração e uso |
KR20210057705A (ko) * | 2018-06-01 | 2021-05-21 | 유니버시티 오브 써던 캘리포니아 | 세포 요법을 위한 다양한 항원 결합 도메인, 신규한 플랫폼 및 다른 향상 |
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2022
- 2022-02-04 WO PCT/US2022/015357 patent/WO2022170126A2/fr active Application Filing
- 2022-02-07 TW TW111104400A patent/TW202246315A/zh unknown
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN114230674A (zh) * | 2020-12-01 | 2022-03-25 | 中国医学科学院基础医学研究所 | 一种含Fc结构域的新型冠状病毒S蛋白受体结合域融合蛋白及其用途 |
CN114230674B (zh) * | 2020-12-01 | 2023-09-26 | 中国医学科学院基础医学研究所 | 一种含Fc结构域的新型冠状病毒S蛋白受体结合域融合蛋白及其用途 |
Also Published As
Publication number | Publication date |
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WO2022170126A2 (fr) | 2022-08-11 |
WO2022170126A3 (fr) | 2022-09-15 |
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