TW202241929A - FimH突變體、其組成物及其用途 - Google Patents

FimH突變體、其組成物及其用途 Download PDF

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Publication number
TW202241929A
TW202241929A TW111101159A TW111101159A TW202241929A TW 202241929 A TW202241929 A TW 202241929A TW 111101159 A TW111101159 A TW 111101159A TW 111101159 A TW111101159 A TW 111101159A TW 202241929 A TW202241929 A TW 202241929A
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Taiwan
Prior art keywords
fimh
polypeptide
val
thr
seq
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TW111101159A
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English (en)
Chinese (zh)
Inventor
真 葛里傑帕斯崔
伊芙萊恩 馬林 維爾登柏格
傑羅恩 葛特森
凱林 克里斯西納 飛
路里斯 賈克伯 菲茲瑪
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美商詹森藥物公司
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Publication of TW202241929A publication Critical patent/TW202241929A/zh

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/245Escherichia (G)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/025Enterobacteriales, e.g. Enterobacter
    • A61K39/0258Escherichia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/10Drugs for disorders of the urinary system of the bladder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70Vectors or expression systems specially adapted for E. coli
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Urology & Nephrology (AREA)
  • General Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
TW111101159A 2021-01-12 2022-01-11 FimH突變體、其組成物及其用途 TW202241929A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP21151126 2021-01-12
EP21151126.6 2021-01-12

Publications (1)

Publication Number Publication Date
TW202241929A true TW202241929A (zh) 2022-11-01

Family

ID=74175646

Family Applications (1)

Application Number Title Priority Date Filing Date
TW111101159A TW202241929A (zh) 2021-01-12 2022-01-11 FimH突變體、其組成物及其用途

Country Status (12)

Country Link
US (3) US11725028B2 (https=)
EP (1) EP4277921A1 (https=)
JP (2) JP7532672B2 (https=)
KR (2) KR20250007029A (https=)
CN (1) CN116888140A (https=)
AR (1) AR124604A1 (https=)
AU (1) AU2022207740B2 (https=)
CA (1) CA3207841A1 (https=)
IL (1) IL303954B2 (https=)
MX (1) MX2023008251A (https=)
TW (1) TW202241929A (https=)
WO (1) WO2022153166A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LT4090363T (lt) 2020-01-16 2024-09-25 Janssen Pharmaceuticals, Inc. Fimh mutantas, kompozicijos su juo ir jų panaudojimas
US11725028B2 (en) 2021-01-12 2023-08-15 Janssen Pharmaceuticals, Inc. FimH mutants, compositions therewith and use thereof
PE20241621A1 (es) * 2021-12-17 2024-08-07 Pfizer Composiciones de polinucleotidos y sus usos

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Publication number Publication date
US11725028B2 (en) 2023-08-15
CN116888140A (zh) 2023-10-13
MX2023008251A (es) 2023-07-26
JP7532672B2 (ja) 2024-08-13
US20220220159A1 (en) 2022-07-14
JP2024109576A (ja) 2024-08-14
IL303954B1 (en) 2024-12-01
AR124604A1 (es) 2023-04-12
AU2022207740B2 (en) 2024-06-06
US20230406890A1 (en) 2023-12-21
US12297238B2 (en) 2025-05-13
KR20250007029A (ko) 2025-01-13
IL303954A (en) 2023-08-01
IL303954B2 (en) 2025-04-01
JP2024502854A (ja) 2024-01-23
CA3207841A1 (en) 2022-07-21
KR102746713B1 (ko) 2024-12-24
KR20230125842A (ko) 2023-08-29
US20250289854A1 (en) 2025-09-18
AU2022207740A1 (en) 2023-06-29
AU2022207740A9 (en) 2024-09-05
EP4277921A1 (en) 2023-11-22
WO2022153166A1 (en) 2022-07-21

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