TW202239762A - 桿狀病毒表現系統 - Google Patents
桿狀病毒表現系統 Download PDFInfo
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- QFJCIRLUMZQUOT-HPLJOQBZSA-N sirolimus Chemical compound C1C[C@@H](O)[C@H](OC)C[C@@H]1C[C@@H](C)[C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@](O)(O2)[C@H](C)CC[C@H]2C[C@H](OC)/C(C)=C/C=C/C=C/[C@@H](C)C[C@@H](C)C(=O)[C@H](OC)[C@H](O)/C(C)=C/[C@@H](C)C(=O)C1 QFJCIRLUMZQUOT-HPLJOQBZSA-N 0.000 description 1
- 150000003384 small molecules Chemical class 0.000 description 1
- 229940063675 spermine Drugs 0.000 description 1
- 238000004114 suspension culture Methods 0.000 description 1
- 239000005460 tetrahydrofolate Substances 0.000 description 1
- 229960002663 thioctic acid Drugs 0.000 description 1
- 230000005026 transcription initiation Effects 0.000 description 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
- 239000012588 trypsin Substances 0.000 description 1
- OUYCCCASQSFEME-UHFFFAOYSA-N tyrosine Natural products OC(=O)C(N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-UHFFFAOYSA-N 0.000 description 1
- 238000000108 ultra-filtration Methods 0.000 description 1
- 230000007502 viral entry Effects 0.000 description 1
- 230000006648 viral gene expression Effects 0.000 description 1
- 239000013603 viral vector Substances 0.000 description 1
Images
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/14011—Baculoviridae
- C12N2710/14041—Use of virus, viral particle or viral elements as a vector
- C12N2710/14043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vectore
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/14011—Baculoviridae
- C12N2710/14041—Use of virus, viral particle or viral elements as a vector
- C12N2710/14044—Chimeric viral vector comprising heterologous viral elements for production of another viral vector
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/00022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/00041—Use of virus, viral particle or viral elements as a vector
- C12N2750/00043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Virology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063038603P | 2020-06-12 | 2020-06-12 | |
| US63/038,603 | 2020-06-12 | ||
| US202163147056P | 2021-02-08 | 2021-02-08 | |
| US63/147,056 | 2021-02-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TW202239762A true TW202239762A (zh) | 2022-10-16 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW110121552A TW202239762A (zh) | 2020-06-12 | 2021-06-11 | 桿狀病毒表現系統 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20230340527A1 (https=) |
| EP (1) | EP4164667A4 (https=) |
| JP (1) | JP2023530277A (https=) |
| KR (1) | KR20230036109A (https=) |
| CN (1) | CN116034160A (https=) |
| AU (1) | AU2021288051A1 (https=) |
| BR (1) | BR112022025221A2 (https=) |
| CA (1) | CA3186872A1 (https=) |
| IL (1) | IL298906A (https=) |
| MX (1) | MX2022015801A (https=) |
| TW (1) | TW202239762A (https=) |
| WO (1) | WO2021252943A2 (https=) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| TW202235622A (zh) * | 2020-12-23 | 2022-09-16 | 美商旗艦先鋒創新公司 | 包裹rna之指環病毒(anellovirus)蛋白殼之活體外組裝 |
| EP4288115A4 (en) * | 2021-02-08 | 2025-06-18 | Flagship Pioneering Innovations V, Inc. | Hybrid aav-anellovectors |
| KR20240114778A (ko) | 2021-12-15 | 2024-07-24 | 플래그쉽 파이어니어링 이노베이션스 브이, 인크. | 표면이 변형된 바이러스 입자 및 모듈형 바이러스 입자 |
| TW202529819A (zh) | 2023-10-13 | 2025-08-01 | 美商旗艦先鋒創新公司 | 組織特異性指環載體(anellovector)遞送 |
| CN117305365B (zh) * | 2023-11-28 | 2024-03-19 | 中国科学院生物物理研究所 | 昆虫细胞—哺乳动物细胞表达穿梭载体SmartBM-1及其应用 |
| WO2025160409A1 (en) | 2024-01-26 | 2025-07-31 | Flagship Pioneering Innovations V, Inc. | Viral vectors for modulating vegf function |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102256997A (zh) * | 2008-10-16 | 2011-11-23 | 美国辉瑞有限公司 | 细环病毒分离株和组合物 |
| WO2011046634A1 (en) * | 2009-10-16 | 2011-04-21 | Pfizer, Inc. | Infectious clones of torque teno virus |
| US9228242B2 (en) * | 2009-08-21 | 2016-01-05 | Virginia Tech Intellectual Properties, Inc. | Porcine torque teno virus vaccines and diagnosis |
| IL271275B1 (en) * | 2017-06-13 | 2026-04-01 | Flagship Pioneering Innovations V Inc | Preparations containing croons and their uses |
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2021
- 2021-06-11 KR KR1020237001348A patent/KR20230036109A/ko active Pending
- 2021-06-11 CA CA3186872A patent/CA3186872A1/en active Pending
- 2021-06-11 JP JP2022576003A patent/JP2023530277A/ja active Pending
- 2021-06-11 US US18/009,476 patent/US20230340527A1/en active Pending
- 2021-06-11 AU AU2021288051A patent/AU2021288051A1/en active Pending
- 2021-06-11 MX MX2022015801A patent/MX2022015801A/es unknown
- 2021-06-11 CN CN202180056408.9A patent/CN116034160A/zh active Pending
- 2021-06-11 IL IL298906A patent/IL298906A/en unknown
- 2021-06-11 EP EP21822121.6A patent/EP4164667A4/en active Pending
- 2021-06-11 BR BR112022025221A patent/BR112022025221A2/pt unknown
- 2021-06-11 TW TW110121552A patent/TW202239762A/zh unknown
- 2021-06-11 WO PCT/US2021/037076 patent/WO2021252943A2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| EP4164667A4 (en) | 2024-10-23 |
| KR20230036109A (ko) | 2023-03-14 |
| BR112022025221A2 (pt) | 2023-03-07 |
| AU2021288051A1 (en) | 2023-01-19 |
| WO2021252943A2 (en) | 2021-12-16 |
| CN116034160A (zh) | 2023-04-28 |
| IL298906A (en) | 2023-02-01 |
| WO2021252943A3 (en) | 2022-01-20 |
| JP2023530277A (ja) | 2023-07-14 |
| MX2022015801A (es) | 2023-05-19 |
| US20230340527A1 (en) | 2023-10-26 |
| CA3186872A1 (en) | 2021-12-16 |
| EP4164667A2 (en) | 2023-04-19 |
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