CN116034160A - 杆状病毒表达系统 - Google Patents

杆状病毒表达系统 Download PDF

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Publication number
CN116034160A
CN116034160A CN202180056408.9A CN202180056408A CN116034160A CN 116034160 A CN116034160 A CN 116034160A CN 202180056408 A CN202180056408 A CN 202180056408A CN 116034160 A CN116034160 A CN 116034160A
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nucleic acid
orf1
sequence
genetic element
molecule
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Pending
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CN202180056408.9A
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English (en)
Chinese (zh)
Inventor
S·德拉格拉夫
J·D·皮茨
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Flagship Pioneering Innovations V Inc
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Flagship Pioneering Innovations V Inc
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Publication of CN116034160A publication Critical patent/CN116034160A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/14011—Baculoviridae
    • C12N2710/14041—Use of virus, viral particle or viral elements as a vector
    • C12N2710/14043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vectore
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/14011—Baculoviridae
    • C12N2710/14041—Use of virus, viral particle or viral elements as a vector
    • C12N2710/14044—Chimeric viral vector comprising heterologous viral elements for production of another viral vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011—Details
    • C12N2750/00022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011—Details
    • C12N2750/00041—Use of virus, viral particle or viral elements as a vector
    • C12N2750/00043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CN202180056408.9A 2020-06-12 2021-06-11 杆状病毒表达系统 Pending CN116034160A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202063038603P 2020-06-12 2020-06-12
US63/038,603 2020-06-12
US202163147056P 2021-02-08 2021-02-08
US63/147,056 2021-02-08
PCT/US2021/037076 WO2021252943A2 (en) 2020-06-12 2021-06-11 Baculovirus expression systems

Publications (1)

Publication Number Publication Date
CN116034160A true CN116034160A (zh) 2023-04-28

Family

ID=78845950

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202180056408.9A Pending CN116034160A (zh) 2020-06-12 2021-06-11 杆状病毒表达系统

Country Status (12)

Country Link
US (1) US20230340527A1 (https=)
EP (1) EP4164667A4 (https=)
JP (1) JP2023530277A (https=)
KR (1) KR20230036109A (https=)
CN (1) CN116034160A (https=)
AU (1) AU2021288051A1 (https=)
BR (1) BR112022025221A2 (https=)
CA (1) CA3186872A1 (https=)
IL (1) IL298906A (https=)
MX (1) MX2022015801A (https=)
TW (1) TW202239762A (https=)
WO (1) WO2021252943A2 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117305365A (zh) * 2023-11-28 2023-12-29 中国科学院生物物理研究所 昆虫细胞—哺乳动物细胞表达穿梭载体SmartBM-1及其应用

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW202235622A (zh) * 2020-12-23 2022-09-16 美商旗艦先鋒創新公司 包裹rna之指環病毒(anellovirus)蛋白殼之活體外組裝
EP4288115A4 (en) * 2021-02-08 2025-06-18 Flagship Pioneering Innovations V, Inc. Hybrid aav-anellovectors
KR20240114778A (ko) 2021-12-15 2024-07-24 플래그쉽 파이어니어링 이노베이션스 브이, 인크. 표면이 변형된 바이러스 입자 및 모듈형 바이러스 입자
TW202529819A (zh) 2023-10-13 2025-08-01 美商旗艦先鋒創新公司 組織特異性指環載體(anellovector)遞送
WO2025160409A1 (en) 2024-01-26 2025-07-31 Flagship Pioneering Innovations V, Inc. Viral vectors for modulating vegf function

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110064758A1 (en) * 2008-10-16 2011-03-17 Pfizer Inc. Infectious clones of torque teno virus
WO2018232017A1 (en) * 2017-06-13 2018-12-20 Flagship Pioneering, Inc. Compositions comprising curons and uses thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011046634A1 (en) * 2009-10-16 2011-04-21 Pfizer, Inc. Infectious clones of torque teno virus
US9228242B2 (en) * 2009-08-21 2016-01-05 Virginia Tech Intellectual Properties, Inc. Porcine torque teno virus vaccines and diagnosis

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110064758A1 (en) * 2008-10-16 2011-03-17 Pfizer Inc. Infectious clones of torque teno virus
US20110150913A1 (en) * 2008-10-16 2011-06-23 Pfizer Inc. Torque teno virus (ttv) isolates and compositions
WO2018232017A1 (en) * 2017-06-13 2018-12-20 Flagship Pioneering, Inc. Compositions comprising curons and uses thereof

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
JOANNA KACZOROWSKA: "Human anelloviruses: diverse, omnipresent and commensal members of the virome", FEMS MICROBIOLOGY REVIEWS, vol. 44, no. 3, 19 March 2020 (2020-03-19) *
K. TAKAHASHI等: "Identification of a new human DNA virus (TTV-like mini virus, TLMV) intermediately related to TT virus and chicken anemia virus", ARCH VIROL, vol. 145, 31 December 2000 (2000-12-31) *
LAURA KAKKOLA等: "Expression of all six human Torque teno virus (TTV) proteins in bacteria and in insect cells, and analysis of their IgG responses", VIROLOGY, vol. 382, 22 October 2008 (2008-10-22) *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117305365A (zh) * 2023-11-28 2023-12-29 中国科学院生物物理研究所 昆虫细胞—哺乳动物细胞表达穿梭载体SmartBM-1及其应用
CN117305365B (zh) * 2023-11-28 2024-03-19 中国科学院生物物理研究所 昆虫细胞—哺乳动物细胞表达穿梭载体SmartBM-1及其应用

Also Published As

Publication number Publication date
EP4164667A4 (en) 2024-10-23
KR20230036109A (ko) 2023-03-14
TW202239762A (zh) 2022-10-16
BR112022025221A2 (pt) 2023-03-07
AU2021288051A1 (en) 2023-01-19
WO2021252943A2 (en) 2021-12-16
IL298906A (en) 2023-02-01
WO2021252943A3 (en) 2022-01-20
JP2023530277A (ja) 2023-07-14
MX2022015801A (es) 2023-05-19
US20230340527A1 (en) 2023-10-26
CA3186872A1 (en) 2021-12-16
EP4164667A2 (en) 2023-04-19

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