TW202233647A - 呼吸治療 - Google Patents
呼吸治療 Download PDFInfo
- Publication number
- TW202233647A TW202233647A TW110142132A TW110142132A TW202233647A TW 202233647 A TW202233647 A TW 202233647A TW 110142132 A TW110142132 A TW 110142132A TW 110142132 A TW110142132 A TW 110142132A TW 202233647 A TW202233647 A TW 202233647A
- Authority
- TW
- Taiwan
- Prior art keywords
- lipopeptide
- acid
- alkyl
- optionally substituted
- side chain
- Prior art date
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- 238000011282 treatment Methods 0.000 title claims abstract description 17
- 230000000241 respiratory effect Effects 0.000 title claims abstract description 16
- 239000000203 mixture Substances 0.000 claims abstract description 116
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims abstract description 115
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- 238000000034 method Methods 0.000 claims abstract description 81
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- C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
- C07K5/101—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
- C07K5/1008—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1016—Tetrapeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Virology (AREA)
- Engineering & Computer Science (AREA)
- Dispersion Chemistry (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pulmonology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Immunology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063114976P | 2020-11-17 | 2020-11-17 | |
| US63/114,976 | 2020-11-17 | ||
| US202163211972P | 2021-06-17 | 2021-06-17 | |
| US63/211,972 | 2021-06-17 |
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| TW202233647A true TW202233647A (zh) | 2022-09-01 |
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| TW110142132A TW202233647A (zh) | 2020-11-17 | 2021-11-12 | 呼吸治療 |
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| EP (1) | EP4247165A4 (https=) |
| JP (1) | JP2023549855A (https=) |
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| AU (1) | AU2021383599A1 (https=) |
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| TW (1) | TW202233647A (https=) |
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| WO2025101524A1 (en) * | 2023-11-06 | 2025-05-15 | Hbc Immunology Inc. | Lipopeptide compounds, and use in modulating eosinophilia |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2546164B1 (fr) * | 1983-05-16 | 1987-07-17 | Centre Nat Rech Scient | Nouveaux derives de peptides, leur preparation et leur application comme inhibiteurs de l'elastase |
| JPH0611754B2 (ja) * | 1985-10-09 | 1994-02-16 | サントリー株式会社 | ペプチダ−ゼ阻害作用を有する新規化合物及びその製法並びに用途 |
| EP0201743B1 (en) * | 1985-04-16 | 1992-04-01 | Suntory Limited | Dipeptide derivatives of fatty acids, process for preparing them, pharmaceutical composition and use |
| AU2003250586B2 (en) * | 2002-08-12 | 2010-09-23 | The Council Of The Queensland Institute Of Medical Research | Novel immunogenic lipopeptides comprising T-helper and B-cell epitopes |
| WO2009046220A2 (en) * | 2007-10-02 | 2009-04-09 | Mdrna, Inc. | Lipopeptides for delivery of nucleic acids |
| KR101250812B1 (ko) * | 2011-03-18 | 2013-04-04 | 미원상사주식회사 | 언데세노일 디펩타이드 유도체 및 이를 함유하는 피부미백용 화장료 조성물 |
| US20140154257A1 (en) * | 2012-06-07 | 2014-06-05 | Luanne Robalo DeChristopher | Materials and methods for diagnosing and treating asthma and dietary Fru-AGEs related disorders including auto-immune and other diseases found to be associated with elevated RAGE. The specification describes methods to identify and make dietary derived advanced glycation end-products, known as Fru-AGEs, Fru-AGE-haptens, and Fru-AGE immune complexes, and to make monoclonal and polyclonal antibodies to this plurality of bio-molecules for use in immunoassays and for use as therapeutic agents |
| US9371276B1 (en) * | 2015-03-21 | 2016-06-21 | Mohan Murali Alapati | Compositions and methods for the treatment of hyperglycemia and metabolic syndrome |
| WO2017068477A1 (en) * | 2015-10-18 | 2017-04-27 | Rao M Surya | Compound, composition and uses thereof |
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2021
- 2021-11-12 TW TW110142132A patent/TW202233647A/zh unknown
- 2021-11-15 US US18/036,382 patent/US20240002436A1/en active Pending
- 2021-11-15 MX MX2023005663A patent/MX2023005663A/es unknown
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- 2021-11-15 KR KR1020237019970A patent/KR20230110295A/ko active Pending
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| WO2022108883A1 (en) | 2022-05-27 |
| CA3199088A1 (en) | 2022-05-27 |
| US20240002436A1 (en) | 2024-01-04 |
| AU2021383599A1 (en) | 2023-05-25 |
| KR20230110295A (ko) | 2023-07-21 |
| EP4247165A4 (en) | 2025-01-22 |
| AU2021383599A9 (en) | 2024-02-08 |
| MX2023005663A (es) | 2023-05-26 |
| EP4247165A1 (en) | 2023-09-27 |
| JP2023549855A (ja) | 2023-11-29 |
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