JP2023549855A - 呼吸器処置 - Google Patents

呼吸器処置 Download PDF

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Publication number
JP2023549855A
JP2023549855A JP2023528658A JP2023528658A JP2023549855A JP 2023549855 A JP2023549855 A JP 2023549855A JP 2023528658 A JP2023528658 A JP 2023528658A JP 2023528658 A JP2023528658 A JP 2023528658A JP 2023549855 A JP2023549855 A JP 2023549855A
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JP
Japan
Prior art keywords
acid
lipopeptide
alkyl
optionally substituted
side chain
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Pending
Application number
JP2023528658A
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English (en)
Japanese (ja)
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JP2023549855A5 (https=
Inventor
ボミ フラムローゼ，
クロフォード リンデン アレクサンダー カリー，
Original Assignee
ホフセス バイオケア アーエスアー
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Publication of JP2023549855A publication Critical patent/JP2023549855A/ja
Publication of JP2023549855A5 publication Critical patent/JP2023549855A5/ja
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/101—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/1008—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1016—Tetrapeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pulmonology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2023528658A 2020-11-17 2021-11-15 呼吸器処置 Pending JP2023549855A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202063114976P 2020-11-17 2020-11-17
US63/114,976 2020-11-17
US202163211972P 2021-06-17 2021-06-17
US63/211,972 2021-06-17
PCT/US2021/059416 WO2022108883A1 (en) 2020-11-17 2021-11-15 Respiratory treatments

Publications (2)

Publication Number Publication Date
JP2023549855A true JP2023549855A (ja) 2023-11-29
JP2023549855A5 JP2023549855A5 (https=) 2024-11-20

Family

ID=81709617

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023528658A Pending JP2023549855A (ja) 2020-11-17 2021-11-15 呼吸器処置

Country Status (9)

Country Link
US (1) US20240002436A1 (https=)
EP (1) EP4247165A4 (https=)
JP (1) JP2023549855A (https=)
KR (1) KR20230110295A (https=)
AU (1) AU2021383599A1 (https=)
CA (1) CA3199088A1 (https=)
MX (1) MX2023005663A (https=)
TW (1) TW202233647A (https=)
WO (1) WO2022108883A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025101524A1 (en) * 2023-11-06 2025-05-15 Hbc Immunology Inc. Lipopeptide compounds, and use in modulating eosinophilia

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6284058A (ja) * 1985-10-09 1987-04-17 Suntory Ltd ペプチダ−ゼ阻害作用を有する新規化合物及びその製法並びに用途
WO2012128464A1 (ko) * 2011-03-18 2012-09-27 미원상사주식회사 언데세노일 디펩타이드 유도체 및 이를 함유하는 피부미백용 화장료 조성물
US20160272582A1 (en) * 2015-03-21 2016-09-22 Mohan Murali Alapati Compositions and methods for the treatment of hyperglycemia and metabolic syndrome
WO2017068477A1 (en) * 2015-10-18 2017-04-27 Rao M Surya Compound, composition and uses thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2546164B1 (fr) * 1983-05-16 1987-07-17 Centre Nat Rech Scient Nouveaux derives de peptides, leur preparation et leur application comme inhibiteurs de l'elastase
EP0201743B1 (en) * 1985-04-16 1992-04-01 Suntory Limited Dipeptide derivatives of fatty acids, process for preparing them, pharmaceutical composition and use
AU2003250586B2 (en) * 2002-08-12 2010-09-23 The Council Of The Queensland Institute Of Medical Research Novel immunogenic lipopeptides comprising T-helper and B-cell epitopes
WO2009046220A2 (en) * 2007-10-02 2009-04-09 Mdrna, Inc. Lipopeptides for delivery of nucleic acids
US20140154257A1 (en) * 2012-06-07 2014-06-05 Luanne Robalo DeChristopher Materials and methods for diagnosing and treating asthma and dietary Fru-AGEs related disorders including auto-immune and other diseases found to be associated with elevated RAGE. The specification describes methods to identify and make dietary derived advanced glycation end-products, known as Fru-AGEs, Fru-AGE-haptens, and Fru-AGE immune complexes, and to make monoclonal and polyclonal antibodies to this plurality of bio-molecules for use in immunoassays and for use as therapeutic agents

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6284058A (ja) * 1985-10-09 1987-04-17 Suntory Ltd ペプチダ−ゼ阻害作用を有する新規化合物及びその製法並びに用途
WO2012128464A1 (ko) * 2011-03-18 2012-09-27 미원상사주식회사 언데세노일 디펩타이드 유도체 및 이를 함유하는 피부미백용 화장료 조성물
US20160272582A1 (en) * 2015-03-21 2016-09-22 Mohan Murali Alapati Compositions and methods for the treatment of hyperglycemia and metabolic syndrome
WO2017068477A1 (en) * 2015-10-18 2017-04-27 Rao M Surya Compound, composition and uses thereof

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
BIOPOLYMERS, vol. 25, JPN6026002745, 1986, pages 1055 - 1067, ISSN: 0005779405 *
JOURNAL OF NATURAL PRODUCTS, vol. 82, JPN6026002746, 2019, pages 2608 - 2619, ISSN: 0005779404 *
MACROMOL. CHEM. PHYS., vol. 202, no. 6, JPN6026002744, 2001, pages 759 - 764, ISSN: 0005779406 *

Also Published As

Publication number Publication date
WO2022108883A1 (en) 2022-05-27
CA3199088A1 (en) 2022-05-27
US20240002436A1 (en) 2024-01-04
AU2021383599A1 (en) 2023-05-25
KR20230110295A (ko) 2023-07-21
EP4247165A4 (en) 2025-01-22
AU2021383599A9 (en) 2024-02-08
MX2023005663A (es) 2023-05-26
EP4247165A1 (en) 2023-09-27
TW202233647A (zh) 2022-09-01

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