TW202108037A - 紫外光管理包裝及保護蓋件 - Google Patents
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Abstract
本文描述一種隱形眼鏡包裝，其含有用於固持一隱形眼鏡之一碗體。該碗體係藉由接合該碗體的一膜來密封，以便在該碗體與該膜之間固持一隱形眼鏡。一鏡片經置放於該碗體與該膜之間的鹽水中。最後，含有附接至該碗體的一光管理保護蓋件。此控制通過該蓋件且至該碗體上的光類型。一般而言，該蓋件係不透紫外光的。
Description
本發明係關於隱形眼鏡消費者所使用的包裝。更具體而言，本包裝幫助抑制紫外光穿過包裝的透射，且因此保護隱形眼鏡免受UV曝露。此特性將可有益於包裝含有任何光敏感性或UV敏感性化合物（諸如藥物及/或光敏感化合物（諸如光致變色化合物））的隱形眼鏡。已知鏡片若曝露於紫外光或可見光，會導致折損光敏感性化合物之功效，雖不至對使用者造成危險，但會失去其獨特產品效益。
隱形眼鏡當前正擴展其供貨選擇，使得產品組合將包括含有光吸收或UV吸收化合物之隱形眼鏡，諸如光致變色隱形眼鏡、或高能量可見(HEV)光吸收隱形眼鏡，其中一些為光敏感性。
舉例而言，目前的主要包裝（聚丙烯泡殼及箔層壓封膜(lidstock)）無法提供對於UV光或可見光之透射的防護，且可造成光致變色鏡片之可能活化，導致鏡片的光疲勞以及其功效的損失。
本發明係提供一種一種隱形眼鏡包裝，其包含：一碗體，其用於固持一隱形眼鏡；一膜，其接合該碗體，以便在該碗體與該膜之間固持一隱形眼鏡；及一光管理保護蓋件，其附接至該碗體，使得該蓋件控制通過該蓋件且至該碗體上的光類型。
本發明另提供一種隱形眼鏡包裝，其包含：一碗體，其用於固持一隱形眼鏡；一大致上半透明蓋件，其置放在該碗體上方；及一光管理保護插件，其附接至該蓋件，使得該插件控制通過該插件且至該蓋件上的光類型。
本發明另提供一種隱形眼鏡包裝，其包含：一碗體，其用於固持一隱形眼鏡；一膜，其接合該碗體，以便在該碗體與該膜之間固持一隱形眼鏡；及及一光管理保護蓋件，其可釋離地附接至該碗體，使得該蓋件控制通過該蓋件且至該碗體上的光類型；及一隱形眼鏡，其被固持在該包裝內。
光敏感性之另一實例包括含有光敏感性化合物（諸如HEV光吸收化合物）的隱形眼鏡，其當曝露於UV光時展現光劣化。光敏感性可藉由在400 nm至450 nm之波長範圍內的至少2百分比之平均透射率變化來表示。可使用各種曝光方法。較佳的光曝露方法係於1996年11月公布之由國際醫藥法規協和會(International Conference on Harmonisation (ICH) of Technical Requirements for Registration of Pharmaceuticals for Human Use guideline)的Q1B新藥物及產品之光穩定性測試(Q1B Photostability Testing of New Drug Substances and Products)所描述者。較佳地，曝光係使用Option 2光源，以1.5192 × 106
勒克司時（168.8小時曝露時間）之估計的照度曝露、及259.4瓦時/m2
（16.2小時曝露時間）之估計的紫外光照射曝露，較佳地於控制在25℃/Amb RH下的光穩定性室中，在ICH光穩定性準則下進行。在曝光後，收集樣本之UV/Vis光譜並且與經保護免受曝露之樣本的光譜比較。舉例而言，根據本發明之含有光敏感性化合物之隱形眼鏡在曝露於如上所述之在ICH準則Q1B條件下（有時在本文中簡稱為「ICH準則Q1B」或「Q1B條件」）的光後，展現在400 nm至450 nm的波長範圍內至少2百分比、或至少5百分比、或至少7百分比、或至少10百分比之其等平均透射率的變化。此種變化可計算為有曝光及無曝光之平均透射率（在指定波長範圍內）之間差的絕對值。
「光致變色化合物(Photochromic compound)」可視為通常在曝露於特定強度及波長的光時可逆地變暗的化合物。
限制高能可見光之一或多種波長的光透射通過鏡片的化合物（例如在400 nm至450 nm的範圍內）可視為「高能可見光吸收」化合物、或「HEV光吸收」化合物。材料吸收特定波長之光的能力可藉由測量其UV/Vis的透射或吸收光譜來判定。
UV光可視為具有在100 nm至400 nm之範圍內的波長之光。
開發「光管理保護蓋件(Light Management Protective Cover, LMPC)」以解決過早使光曝露至光致變色及其他光敏感性產品的問題。LMPC係在目前隱形眼鏡主要包裝表面上使用的可附接或經黏著/接合的蓋件/遮蓋，以防止/限制使光曝露（包括但不限於UV）至其內容物（包括但不限於隱形眼鏡）。
LMPC係在滅菌後施加至該隱形眼鏡碗體的下側，並且意欲保持固定至主要包裝的外側。因此，本發明不會影響與鏡片包裝一起使用的熱封或滅菌程序，其為用於確保滅菌阻障包裝系統的兩個最重要處理技術。此外，LPMC蓋件不會與包裝溶液或實體鏡片本身接觸，且該主要包裝碗體提供介於蓋件與鏡片之間足夠的阻障。因此，此解決方案減少關於該蓋件之任何材料浸入於包裝內部中之任何者、浸入含有鏡片的溶液、或浸入於鏡片本身的疑慮，因為所有這些元件從未與LPMC接觸。
如圖1所見，描述在蓋件100上將與標準隱形眼鏡包裝200搭配使用的扣合件，如圖1B中所見。蓋件100具有呈現為凸片105之扣合(snap-on)特徵，該凸片經置放在蓋件100之一端處。這些凸片105與包裝200上的凸緣205緊密配接。因此，蓋件100能夠附接至包裝200之碗體部分210，而不需要另行將蓋件100接合至碗體210，或實際上至包裝200。
如前文所提及，蓋件100係不透明且阻擋紫外光，使得若有置放於碗體210中之一隱形眼鏡而使得該鏡片被光活化，該蓋件會防止鏡片無意的活化，或替代地防止存在於鏡片中的藥物劣化。
圖2描述圖1之蓋件的修改。如圖2中可見，描述一蓋件120，其含有在凸緣122、124上之扣合件。這些凸緣122、124經提供在蓋件120的任一端121、123處，使得蓋件120可附接在泡殼包裝200的兩端，即為在圖1之蓋件100的描述中展示的相同包裝200。圖2之經修改設計120確保蓋件120與包裝200之間更佳的接觸，從而減少光穿透過其中的可能性。此特徵使蓋件120能夠附接至包裝200之碗體210，而無需在蓋件120與碗體210之間建立任何種類的接合。
圖3A、圖3B、及圖3C描述前述設計的進一步修改。如在這些圖式中所見，蓋件100、120之「扣合」特徵被移除。現在，蓋件140、145及150併入用於超音波焊接的特徵。此等係在這三個圖式之各者中描述為所見的凸片142、147、152。這些修改現在進一步減少鏡片曝露於光的可能性。如圖3A、圖3B及圖3C中所見，進一步強化蓋件140、145或150與碗體210之間的接觸，使得任何扣合特徵被消除。凸緣142、147、152之各者可藉由超音波或熱端焊接程序來熔合接合或焊接至碗體210，其等係包裝產業中已知的標準技術。
圖4A、圖4B及圖4C描述圖3A、圖3B及圖3C之概念的進一步修改。現在，如圖4A、圖4B及圖4C中可見，提供較大的焊接點，其提供隔開鄰接包裝200之碗體210之熱密封環220的距離。這些延伸翼或尾部129、149、159使蓋件225至包裝碗體210的焊接能夠與熱密封環220隔開。此特徵確保對於在碗體210與包裝封膜之間已經產生之熱密封接合的最小損害，並且在包裝200上維持滅菌阻障。該封膜係由可壓力成形箔所形成，包括經層壓聚酯及鋁箔層壓複合物。
最後，圖5展示在圖4C中所見之蓋件的「方形化(squared up)」修改，使得降低光滲漏的可能。提供蓋件500至包裝550之附接，使得有一增加的表面積用於焊接。此特徵提供碗體510之強化覆蓋，使碗體510至蓋件500之焊接更容易，且與熱密封環隔開更遠。
如最佳於圖5可見，蓋件500及包裝550經理想地設計用於容納光致變色隱形眼鏡。該包裝經組態以處理及最小化光致變色隱形眼鏡之UV曝露。用於蓋件500的較佳材料係具有UV阻斷劑及TiO2之聚丙烯。當與由聚丙烯所形成且具有介於0.55 mm與0.85 mm之間的壁厚度的一般隱形眼鏡包裝搭配使用時，蓋件500的較佳材料厚度約為0.375 mm。此允許蓋件為柔軟但又堅固地附接至包裝550。然而瞭解到，蓋件500之厚度可在0.025 mm至1.0 mm之範圍內，以滿足特定產品要求。同樣地，當然亦可使用其他材料，也將於下文說明。
設想可用作為LMPC蓋件的材料的範圍相當廣。選擇材料應與用於主要包裝550且特別是碗體510的材料相容，使得當熔融接合或焊接時，形成兩種材料之間的接合。舉例來說，如果碗體510係由聚丙烯製成，則用於作為蓋件500的較佳材料亦為聚丙烯，雖然可使用任何其他熱塑性聚合物，諸如基於丙烯之彈性體、聚丙烯與聚乙烯之摻合物、EVA等。所需要的是，蓋件500能夠限制UV光通過。
同樣地，如果碗體510係由環烯烴聚合物(COP)製成，LMPC蓋件500的較佳材料選項亦為COP，但可使用任何其他熱塑性聚合物，諸如COP摻合物、環烯烴共聚物(COC)或COC摻合物、EVA等、或任何其他UV限制材料。取決於產品關鍵品質因素要求(CTQs)及主要包裝碗體510的材料組成，蓋件500應含有具有或不具有添加劑（諸如TiO2
、UV阻斷劑、著色母料等）的相容熱塑性樹脂。蓋件500中的UV吸收劑可為諸如以下之材料的添加劑：苯并三唑；二苯基酮(benzophenone)；三
；或這些添加劑中之兩者或更多者之組合。
蓋件500應固定地附接至包裝550。較佳的固定方法係藉由將蓋件500熱焊接至泡殼包裝來將該蓋件接合至泡殼包裝，諸如藉由使用熱工具尖端作為外部熱源，以在蓋件500周圍的具體有用區施加熱。此處所指的施加熱，將傾向最低程度地但又充分地熔化形成蓋件500的聚合物，從而在蓋件500與包裝550之表面之間建立機械接合。自然地，設想可利用其他附接手段，諸如熱附接（雷射、紅外線）及摩擦（諸如振動、超音波）接合技術之形式。
如圖6A及圖6B可見，描述本發明之包裝的進一步修改。在此，包裝600具有附接至碗體605的預成形蓋件601。此蓋件601一般係藉由射出成型製成。蓋件601通常藉由雷射焊接、後期製作來附接至碗體605。當然，其為不透UV光的，與本發明之揭露一致。蓋件601通常經按壓適配至碗體605中，但替代地其可經雷射焊接或音波焊接至碗體605。如圖605中可見，包裝之組態使得可在生產中形成一串之包裝600。然後，可將蓋件601連續地施加至碗體605。
以此方式，包裝之開啟及閉合功能不會被影響，也不能被影響。然而，由於附接至隱形眼鏡包裝之本發明的蓋件，特定形式的光（諸如UV光）被抑制而不穿透包裝（例如包裝550）及含在其內部溶液中之隱形眼鏡570。此配置保存鏡片之光致變色態樣的功能。
上文實施例中所描述之包裝亦可用於保護含有其他光敏感性化合物之隱形眼鏡，包括光敏性HEV吸收化合物。
前述發明應與隨附之申請專利範圍一併理解，考慮到所有適當的等效物。
[相關申請案之交互參照]
本申請案係於2019年7月17日申請之序號第16/514437號之部分延續申請案，該案全文以引用方式併入本文中。
100:蓋件
105:凸片
120:蓋件
121:端
122:凸緣
123:端
124:凸緣
129:延伸翼或尾部
140:蓋件
142:凸緣
145:蓋件
147:凸緣
149:延伸翼或尾部
150:蓋件
152:凸緣
159:延伸翼或尾部
200:包裝
205:凸緣
210:碗體
220:熱密封環
225:蓋件
500:蓋件
510:碗體
550:包裝
570:隱形眼鏡
600:包裝
601:蓋件
605:碗體
［圖1］係根據本文所包含之本發明描述所製造的隱形眼鏡包裝蓋件之透視圖，其與如圖1B與圖1C（分別為平視圖及立視圖，無蓋件）之隱形眼鏡泡殼碗體(blister bowl)搭配使用；
［圖2］係對圖1之包裝的一修改的透視圖；
［圖3A］、［圖3B］及［圖3C］係本發明之進一步修改，其中蓋件經超音波焊接至包裝；
［圖4A］、［圖4B］及［圖4C］係圖3A、圖3B及圖3C之蓋件之修改；
［圖5］描述將蓋件附接至包裝的進一步組態；及
［圖6A］及［圖6B］描述附接至鏡片包裝之蓋件的其他修改。
100:蓋件
105:凸片
200:包裝
205:凸緣
210:碗體
Claims (18)
- 一種隱形眼鏡包裝，其包含： 一碗體，其用於固持一隱形眼鏡； 一膜，其接合該碗體，以便在該碗體與該膜之間固持一隱形眼鏡；及 及一光管理保護蓋件，其附接至該碗體，使得該蓋件控制通過該蓋件且至該碗體上的光類型。
- 如請求項1所述之包裝，其中該蓋件防止紫外光通過。
- 如請求項1所述之包裝，其中該碗體大致上為半透明。
- 如請求項1所述之包裝，其中該蓋件扣合在該碗體上方。
- 如請求項1所述之包裝，其中該蓋件經焊接至該碗體。
- 如請求項1所述之包裝，其中該蓋件進一步含有供一使用者之手指抓握的凸緣。
- 如請求項1所述之包裝，其中該蓋件經超音波焊接至該碗體。
- 一種隱形眼鏡包裝，其包含： 一碗體，其用於固持一隱形眼鏡； 一大致上半透明蓋件，其置放在該碗體上方；及 及一光管理保護插件，其附接至該蓋件，使得該插件控制通過該插件且至該蓋件上的光類型。
- 如請求項8所述之包裝，其中該蓋件防止紫外光通過。
- 如請求項8所述之包裝，其中該碗體大致上為半透明。
- 如請求項8所述之包裝，其中該蓋件扣合在該碗體上方。
- 如請求項8所述之包裝，其中該蓋件經焊接至該碗體。
- 如請求項8所述之包裝，其中該蓋件進一步含有供一使用者之手指抓握的凸緣。
- 如請求項8所述之包裝，其中該蓋件經焊接至該碗體。
- 組合：一隱形眼鏡包裝，其包含： 一碗體，其用於固持一隱形眼鏡； 一膜，其接合該碗體，以便在該碗體與該膜之間固持一隱形眼鏡；及 及一光管理保護蓋件，其可釋離地附接至該碗體，使得該蓋件控制通過該蓋件且至該碗體上的光類型；及 一隱形眼鏡，其被固持在該包裝內。
- 一種蓋件，其經調適以置放在該碗體上方形成一隱形眼鏡包裝之外側，該蓋件阻擋紫外光通過至該碗體中。
- 如請求項15所述之包裝，其進一步包括附接至該碗體的一封膜(lidstock)，該封膜係由一可壓力成形箔所形成。
- 如請求項17所述之包裝，其中該可壓力成形箔係一層壓聚酯或一鋁箔複合物。
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|---|---|---|---|
| US16/514,437 US20210015227A1 (en) | 2019-07-17 | 2019-07-17 | UV Light Management Package and Protective Cover |
| US16/514,437 | 2019-07-17 | ||
| US16/901,097 US20210018661A1 (en) | 2019-07-17 | 2020-06-15 | UV Light Management Package and Protective Cover |
| US16/901,097 | 2020-06-15 |
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| TW202108037A true TW202108037A (zh) | 2021-03-01 |
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| EP (1) | EP3766800A1 (zh) |
| JP (1) | JP2021018439A (zh) |
| KR (1) | KR20210010380A (zh) |
| CN (1) | CN112239015A (zh) |
| AU (1) | AU2020204376A1 (zh) |
| MA (1) | MA53839A (zh) |
| TW (1) | TW202108037A (zh) |
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| TWI821026B (zh) * | 2022-11-17 | 2023-11-01 | 晶碩光學股份有限公司 | 舒壓隱形眼鏡 |
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| US11360240B2 (en) | 2019-12-19 | 2022-06-14 | Johnson & Johnson Vision Care, Inc. | Contact lens containing photosensitive chromophore and package therefor |
| JP1669253S (zh) * | 2020-03-10 | 2020-09-28 | ||
| USD965287S1 (en) * | 2021-12-30 | 2022-10-04 | Shenzhen Xin'an Innovation Technology Co., Ltd. | GPS case |
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|---|---|---|---|---|
| JPH01279222A (ja) * | 1988-05-02 | 1989-11-09 | Masaaki Haga | コンタクトレンズ簡易保存容器 |
| NZ250453A (en) * | 1992-12-21 | 1996-12-20 | Johnson & Johnson Vision Prod | Ophthalmic lens package; planar surface with concave bowl for containing lens, sealing sheet covering bowl with lens therein |
| US5375698A (en) * | 1993-05-07 | 1994-12-27 | Allergan, Inc. | Prefilled, resealable contact lens container |
| EP0694017A1 (en) * | 1993-04-21 | 1996-01-31 | Allergan, Inc. | Contact lens containers and methods of using |
| JP4550352B2 (ja) * | 2002-07-22 | 2010-09-22 | 富山化学工業株式会社 | 透明包装袋及びこれで外包装された液状製剤包装体 |
| CA2498678A1 (en) * | 2002-09-13 | 2004-03-25 | 1-800 Contacts, Inc. | Contact lens package and storage case, holder, and system and method of making and using |
| US7404994B2 (en) * | 2003-03-12 | 2008-07-29 | Reynolds Packaging Llc | Lidstock material having improved burst strength |
| US20050205451A1 (en) * | 2004-03-18 | 2005-09-22 | Brown-Skrobot Susan K | Contact lens packages |
| US8459445B2 (en) * | 2006-07-21 | 2013-06-11 | Menicon, Co., Ltd. | Colored contact lens primary packaging |
| EP2407817B1 (en) * | 2009-03-12 | 2013-12-18 | Menicon Co., Ltd. | Storage method for contact lens and contact lens package |
| US8365910B2 (en) * | 2011-06-02 | 2013-02-05 | Cook Medical Technologies Llc | Medical device packaging |
| SG189576A1 (en) * | 2011-10-18 | 2013-05-31 | Menicon Singapore Pte Ltd | Packaging for disposable soft contact lenses having pre-formed multi-layer structural laminate |
| KR101836759B1 (ko) * | 2014-03-31 | 2018-03-08 | 쿠퍼비젼 인터내셔날 홀딩 캄파니, 엘피 | 콘택트 렌즈 포장 및 포장된 콘택트 렌즈를 제조하는 방법 |
-
2020
- 2020-06-15 US US16/901,097 patent/US20210018661A1/en not_active Abandoned
- 2020-06-30 AU AU2020204376A patent/AU2020204376A1/en active Pending
- 2020-07-15 KR KR1020200087469A patent/KR20210010380A/ko unknown
- 2020-07-15 TW TW109123825A patent/TW202108037A/zh unknown
- 2020-07-16 MA MA053839A patent/MA53839A/fr unknown
- 2020-07-16 EP EP20186313.1A patent/EP3766800A1/en not_active Withdrawn
- 2020-07-16 JP JP2020121969A patent/JP2021018439A/ja active Pending
- 2020-07-17 CN CN202010691601.7A patent/CN112239015A/zh active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI821026B (zh) * | 2022-11-17 | 2023-11-01 | 晶碩光學股份有限公司 | 舒壓隱形眼鏡 |
Also Published As
| Publication number | Publication date |
|---|---|
| MA53839A (fr) | 2021-12-01 |
| US20210018661A1 (en) | 2021-01-21 |
| RU2020123085A3 (zh) | 2022-01-13 |
| AU2020204376A1 (en) | 2021-02-04 |
| KR20210010380A (ko) | 2021-01-27 |
| CN112239015A (zh) | 2021-01-19 |
| RU2020123085A (ru) | 2022-01-13 |
| JP2021018439A (ja) | 2021-02-15 |
| EP3766800A1 (en) | 2021-01-20 |
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